LTC1412357I2 - Beta-amino tetrahidroimidazo(1,2-a)pirazinai ir tetrahidrotrazolo(4,3-A)pirazinai kaip dipeptidilpeptidazės inhibitoriai, skirti diabeto gydymui arba prevencijai - Google Patents

Beta-amino tetrahidroimidazo(1,2-a)pirazinai ir tetrahidrotrazolo(4,3-A)pirazinai kaip dipeptidilpeptidazės inhibitoriai, skirti diabeto gydymui arba prevencijai

Info

Publication number
LTC1412357I2
LTC1412357I2 LTPA2007006C LTPA2007006C LTC1412357I2 LT C1412357 I2 LTC1412357 I2 LT C1412357I2 LT PA2007006 C LTPA2007006 C LT PA2007006C LT PA2007006 C LTPA2007006 C LT PA2007006C LT C1412357 I2 LTC1412357 I2 LT C1412357I2
Authority
LT
Lithuania
Prior art keywords
pyrazines
tetrahydrotrazole
diabetes
beta
prevention
Prior art date
Application number
LTPA2007006C
Other languages
English (en)
Lithuanian (lt)
Original Assignee
Merck Sharp & Dohme Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23172273&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LTC1412357(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp & Dohme Corp. filed Critical Merck Sharp & Dohme Corp.
Publication of LTPA2007006I1 publication Critical patent/LTPA2007006I1/lt
Publication of LTC1412357I2 publication Critical patent/LTC1412357I2/lt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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LTPA2007006C 2001-07-06 2007-09-12 Beta-amino tetrahidroimidazo(1,2-a)pirazinai ir tetrahidrotrazolo(4,3-A)pirazinai kaip dipeptidilpeptidazės inhibitoriai, skirti diabeto gydymui arba prevencijai LTC1412357I2 (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30347401P 2001-07-06 2001-07-06
PCT/US2002/021349 WO2003004498A1 (en) 2001-07-06 2002-07-05 Beta-amino tetrahydroimidazo (1, 2-a) pyrazines and tetrahydrotrioazolo (4, 3-a) pyrazines as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes

Publications (2)

Publication Number Publication Date
LTPA2007006I1 LTPA2007006I1 (lt) 2020-04-27
LTC1412357I2 true LTC1412357I2 (lt) 2021-01-11

Family

ID=23172273

Family Applications (1)

Application Number Title Priority Date Filing Date
LTPA2007006C LTC1412357I2 (lt) 2001-07-06 2007-09-12 Beta-amino tetrahidroimidazo(1,2-a)pirazinai ir tetrahidrotrazolo(4,3-A)pirazinai kaip dipeptidilpeptidazės inhibitoriai, skirti diabeto gydymui arba prevencijai

Country Status (45)

Country Link
US (9) US6699871B2 (instruction)
EP (4) EP1625847B1 (instruction)
JP (1) JP3762407B2 (instruction)
KR (1) KR100606871B1 (instruction)
CN (2) CN1861077A (instruction)
AR (1) AR036114A1 (instruction)
AT (2) ATE471148T1 (instruction)
AU (1) AU2002320303B2 (instruction)
BE (1) BE2007C047I2 (instruction)
BG (1) BG108493A (instruction)
BR (1) BRPI0210866B8 (instruction)
CA (1) CA2450740C (instruction)
CR (1) CR7235A (instruction)
CY (3) CY2007019I2 (instruction)
DE (4) DE122007000056I1 (instruction)
DK (2) DK1625847T3 (instruction)
DO (1) DOP2002000438A (instruction)
EA (2) EA012701B1 (instruction)
EC (1) ECSP044935A (instruction)
ES (2) ES2259713T3 (instruction)
FR (2) FR07C0041I2 (instruction)
GE (2) GEP20053734B (instruction)
HR (1) HRP20031098B1 (instruction)
HU (2) HU225695B1 (instruction)
IL (3) IL159109A0 (instruction)
IS (2) IS2218B (instruction)
JO (1) JO2230B1 (instruction)
LT (1) LTC1412357I2 (instruction)
LU (2) LUC91360I2 (instruction)
MA (1) MA27053A1 (instruction)
ME (1) ME00439B (instruction)
MX (1) MXPA04000018A (instruction)
MY (1) MY127961A (instruction)
NL (2) NL300287I2 (instruction)
NO (4) NO321999B1 (instruction)
NZ (1) NZ529833A (instruction)
PE (1) PE20030654A1 (instruction)
PL (1) PL196278B6 (instruction)
PT (2) PT1412357E (instruction)
RS (1) RS50737B (instruction)
SI (1) SI1412357T1 (instruction)
TW (1) TWI226331B (instruction)
UA (1) UA74912C2 (instruction)
WO (1) WO2003004498A1 (instruction)
ZA (1) ZA200309294B (instruction)

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PL376822A1 (pl) 2002-11-07 2006-01-09 Merck & Co., Inc. Pochodne fenyloalaniny jako inhibitory dipeptydylopeptydazy do leczenia lub zapobiegania cukrzycy
WO2004050022A2 (en) * 2002-12-04 2004-06-17 Merck & Co., Inc. Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
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