WO2002076396A3 - Compounds useful as kinase inhibitors for the treatment of hyperproliferative diseases - Google Patents

Compounds useful as kinase inhibitors for the treatment of hyperproliferative diseases Download PDF

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Publication number
WO2002076396A3
WO2002076396A3 PCT/US2002/008968 US0208968W WO02076396A3 WO 2002076396 A3 WO2002076396 A3 WO 2002076396A3 US 0208968 W US0208968 W US 0208968W WO 02076396 A3 WO02076396 A3 WO 02076396A3
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
kinase inhibitors
compounds useful
hyperproliferative diseases
hyperproliferative
Prior art date
Application number
PCT/US2002/008968
Other languages
French (fr)
Other versions
WO2002076396A2 (en
Inventor
William E Bondinell
Dennis A Holt
Maria Amparo Lago
Michael J Neeb
Marcus A Semones
Original Assignee
Smithkline Beecham Corp
William E Bondinell
Dennis A Holt
Maria Amparo Lago
Michael J Neeb
Marcus A Semones
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, William E Bondinell, Dennis A Holt, Maria Amparo Lago, Michael J Neeb, Marcus A Semones filed Critical Smithkline Beecham Corp
Priority to AU2002303145A priority Critical patent/AU2002303145A1/en
Publication of WO2002076396A2 publication Critical patent/WO2002076396A2/en
Publication of WO2002076396A3 publication Critical patent/WO2002076396A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

Novel kinase inhibitors and methods of using them are provided.
PCT/US2002/008968 2001-03-23 2002-03-22 Compounds useful as kinase inhibitors for the treatment of hyperproliferative diseases WO2002076396A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002303145A AU2002303145A1 (en) 2001-03-23 2002-03-22 Compounds useful as kinase inhibitors for the treatment of hyperproliferative diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27811701P 2001-03-23 2001-03-23
US60/278,117 2001-03-23

Publications (2)

Publication Number Publication Date
WO2002076396A2 WO2002076396A2 (en) 2002-10-03
WO2002076396A3 true WO2002076396A3 (en) 2002-12-19

Family

ID=23063740

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/008968 WO2002076396A2 (en) 2001-03-23 2002-03-22 Compounds useful as kinase inhibitors for the treatment of hyperproliferative diseases

Country Status (2)

Country Link
AU (1) AU2002303145A1 (en)
WO (1) WO2002076396A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR045037A1 (en) 2003-07-10 2005-10-12 Aventis Pharma Sa TETRAHIDRO-1H-PIRAZOLO [3,4-C] SUBSTITUTED PYRIDINS, COMPOSITIONS THAT CONTAIN THEM AND ITS USE.
GB0614471D0 (en) 2006-07-20 2006-08-30 Syngenta Ltd Herbicidal Compounds
US8048892B2 (en) 2006-12-18 2011-11-01 Amgen Inc. Azaquinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
WO2008076427A2 (en) 2006-12-18 2008-06-26 Amgen Inc. Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
WO2008130600A2 (en) 2007-04-18 2008-10-30 Amgen Inc. Quinolones and azaquinolones that inhibit prolyl hydroxylase
WO2008130508A1 (en) 2007-04-18 2008-10-30 Amgen Inc. Indanone derivatives that inhibit prolyl hydroxylase
EP2150251B9 (en) 2007-05-04 2013-02-27 Amgen, Inc Thienopyridine and thiazolopyridine derivatives that inhibit prolyl hydroxylase activity
WO2008137084A2 (en) 2007-05-04 2008-11-13 Amgen Inc. Diazaquinolones that inhibit prolyl hydroxylase activity
US20100190777A1 (en) 2007-07-17 2010-07-29 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
US8389533B2 (en) 2008-04-07 2013-03-05 Amgen Inc. Gem-disubstituted and spirocyclic amino pyridines/pyrimidines as cell cycle inhibitors
NZ762856A (en) 2017-10-05 2020-07-31 Fulcrum Therapeutics Inc P38 kinase inhibitors reduce dux4 and downstream gene expression for the treatment of fshd
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1195378A1 (en) * 2000-10-03 2002-04-10 Warner-Lambert Company Pyridotriazines and pyridopyridazines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1195378A1 (en) * 2000-10-03 2002-04-10 Warner-Lambert Company Pyridotriazines and pyridopyridazines

Also Published As

Publication number Publication date
AU2002303145A1 (en) 2002-10-08
WO2002076396A2 (en) 2002-10-03

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