KR20060130552A - 비절단성 링커를 통해 연결된 세포결합물질 메이탠시노이드접합체를 사용한 특정세포집단 표적화 방법, 상기 접합체및 상기 접합체 생산방법 - Google Patents

비절단성 링커를 통해 연결된 세포결합물질 메이탠시노이드접합체를 사용한 특정세포집단 표적화 방법, 상기 접합체및 상기 접합체 생산방법 Download PDF

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KR20060130552A
KR20060130552A KR1020067006874A KR20067006874A KR20060130552A KR 20060130552 A KR20060130552 A KR 20060130552A KR 1020067006874 A KR1020067006874 A KR 1020067006874A KR 20067006874 A KR20067006874 A KR 20067006874A KR 20060130552 A KR20060130552 A KR 20060130552A
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cell
maytansinoid
cell binding
binding material
ester
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KR1020067006874A
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English (en)
Korean (ko)
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리타 스티브스
로버트 루츠
라비 체리
홍시엥 시에
옐레나 코브툰
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이뮤노젠 아이엔씨
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    • C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
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KR1020067006874A 2003-10-10 2004-10-12 비절단성 링커를 통해 연결된 세포결합물질 메이탠시노이드접합체를 사용한 특정세포집단 표적화 방법, 상기 접합체및 상기 접합체 생산방법 KR20060130552A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US50990103P 2003-10-10 2003-10-10
US60/509,901 2003-10-10
US10/960,602 2004-10-08
US10/960,602 US8088387B2 (en) 2003-10-10 2004-10-08 Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates

Related Child Applications (2)

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