WO2012135522A2 - Process for manufacturing conjugates of improved homogeneity - Google Patents

Process for manufacturing conjugates of improved homogeneity Download PDF

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Publication number
WO2012135522A2
WO2012135522A2 PCT/US2012/031253 US2012031253W WO2012135522A2 WO 2012135522 A2 WO2012135522 A2 WO 2012135522A2 US 2012031253 W US2012031253 W US 2012031253W WO 2012135522 A2 WO2012135522 A2 WO 2012135522A2
Authority
WO
WIPO (PCT)
Prior art keywords
process
cell
anti
antibody
acid
Prior art date
Application number
PCT/US2012/031253
Other languages
French (fr)
Other versions
WO2012135522A3 (en
Inventor
Shengjin Jin
Original Assignee
Immunogen, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201161468981P priority Critical
Priority to US201161468997P priority
Priority to US61/468,981 priority
Priority to US61/468,997 priority
Application filed by Immunogen, Inc. filed Critical Immunogen, Inc.
Priority claimed from BR112013025228A external-priority patent/BR112013025228A2/en
Publication of WO2012135522A2 publication Critical patent/WO2012135522A2/en
Publication of WO2012135522A3 publication Critical patent/WO2012135522A3/en

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