JP4620253B2 - 菌類細胞中で遺伝子を発現させるためのプロモーター - Google Patents

菌類細胞中で遺伝子を発現させるためのプロモーター Download PDF

Info

Publication number
JP4620253B2
JP4620253B2 JP2000606759A JP2000606759A JP4620253B2 JP 4620253 B2 JP4620253 B2 JP 4620253B2 JP 2000606759 A JP2000606759 A JP 2000606759A JP 2000606759 A JP2000606759 A JP 2000606759A JP 4620253 B2 JP4620253 B2 JP 4620253B2
Authority
JP
Japan
Prior art keywords
seq
promoter
nucleic acid
polypeptide
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2000606759A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002539793A (ja
JP2002539793A5 (https=
Inventor
エム． バーカ，ランディー
ダブリュ． レイ，マイケル
ブラウン，キンバリー
エイチ． ブラウン，スティーブン
Original Assignee
ノボザイムス，インコーポレイティド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノボザイムス，インコーポレイティド filed Critical ノボザイムス，インコーポレイティド
Publication of JP2002539793A publication Critical patent/JP2002539793A/ja
Publication of JP2002539793A5 publication Critical patent/JP2002539793A5/ja
Application granted granted Critical
Publication of JP4620253B2 publication Critical patent/JP4620253B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
JP2000606759A 1999-03-22 2000-03-22 菌類細胞中で遺伝子を発現させるためのプロモーター Expired - Fee Related JP4620253B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27444999A 1999-03-22 1999-03-22
US09/274,449 1999-03-22
PCT/US2000/007815 WO2000056900A2 (en) 1999-03-22 2000-03-22 Promoter sequences derived from fusarium venenatum and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010109995A Division JP5264825B2 (ja) 1999-03-22 2010-05-12 菌類細胞中で遺伝子を発現させるためのプロモーター

Publications (3)

Publication Number Publication Date
JP2002539793A JP2002539793A (ja) 2002-11-26
JP2002539793A5 JP2002539793A5 (https=) 2007-05-17
JP4620253B2 true JP4620253B2 (ja) 2011-01-26

Family

ID=23048245

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2000606759A Expired - Fee Related JP4620253B2 (ja) 1999-03-22 2000-03-22 菌類細胞中で遺伝子を発現させるためのプロモーター
JP2010109995A Expired - Fee Related JP5264825B2 (ja) 1999-03-22 2010-05-12 菌類細胞中で遺伝子を発現させるためのプロモーター
JP2013021124A Pending JP2013121360A (ja) 1999-03-22 2013-02-06 菌類細胞中で遺伝子を発現させるためのプロモーター
JP2013021169A Ceased JP2013121361A (ja) 1999-03-22 2013-02-06 菌類細胞中で遺伝子を発現させるためのプロモーター

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2010109995A Expired - Fee Related JP5264825B2 (ja) 1999-03-22 2010-05-12 菌類細胞中で遺伝子を発現させるためのプロモーター
JP2013021124A Pending JP2013121360A (ja) 1999-03-22 2013-02-06 菌類細胞中で遺伝子を発現させるためのプロモーター
JP2013021169A Ceased JP2013121361A (ja) 1999-03-22 2013-02-06 菌類細胞中で遺伝子を発現させるためのプロモーター

Country Status (6)

Country Link
EP (2) EP2278016B1 (https=)
JP (4) JP4620253B2 (https=)
CN (5) CN100482801C (https=)
AU (1) AU4025700A (https=)
DK (1) DK2278016T3 (https=)
WO (1) WO2000056900A2 (https=)

Families Citing this family (493)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7883872B2 (en) 1996-10-10 2011-02-08 Dyadic International (Usa), Inc. Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose
ES2237159T3 (es) 1998-10-06 2005-07-16 Mark Aaron Emalfarb Sistema de transformacion en el campo de los hongos micoticos filamentosos en chrysosporium.
DE10036491A1 (de) 2000-07-25 2002-02-07 Roche Diagnostics Gmbh Expression von Alkalischer Phosphatase in Hefe
US7063962B2 (en) * 2001-07-20 2006-06-20 Novozymes A/S DNA sequences for regulating transcription
AUPR945901A0 (en) 2001-12-13 2002-01-24 Macquarie University Gene promoters
WO2004046373A2 (en) 2002-11-18 2004-06-03 Novozymes Biotech, Inc. Promoter variants for expressing genes in a fungal cell
DE602004022929D1 (de) 2003-03-31 2009-10-15 Novozymes Inc Verfahren zur produktion biologischer substanzen i
ES2437198T3 (es) 2003-10-28 2014-01-09 Novozymes Inc. Polipéptidos con actividad de beta-glucosidasa y polinucleótidos aislados que codifican los polipéptidos
ES2468366T3 (es) 2004-01-30 2014-06-16 Novozymes Inc. Polip�ptidos con actividad de mejora celulol�tica y polinucle�tidos que los codifican
EP1715736A4 (en) 2004-02-12 2008-09-03 Novozymes Inc POLYPEPTIDES HAVING XYLANASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME
DK1735454T3 (en) 2004-03-25 2017-08-28 Novozymes Inc PROCEDURES FOR DEVELOPMENT OR CONVERSION OF PLANT CELL CELL POLICY ACCHARIDES
US9045748B2 (en) 2004-05-27 2015-06-02 Novozymes, Inc. Methods for transforming and expression screening of filamentous fungal cells with a DNA library
CN104195123A (zh) 2004-06-29 2014-12-10 诺维信股份有限公司 具有α-葡糖苷酶活性的多肽及编码其的多核苷酸
CN1308452C (zh) * 2004-09-14 2007-04-04 上海永业农科生物工程有限公司 一种含有改组乙醇氧化酶启动子的毕赤酵母植酸酶表达系统
EP2295555A3 (en) 2004-09-30 2011-08-10 Novozymes, Inc. Polypeptides having lipase activity and polynucleotides encodig same
EP1809747B1 (en) 2004-10-04 2016-12-14 Novozymes A/S Polypeptides having phytase activity and polynucleotides encoding same
AR050895A1 (es) 2004-10-04 2006-11-29 Novozymes As Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican
EP1814996A2 (en) 2004-11-19 2007-08-08 Novozymes A/S Polypeptides having antimicrobial activity and polynucleotides encoding same
EP2365068B1 (en) 2004-12-22 2017-03-01 Novozymes A/S Enzymes for starch processing
CN101194015B (zh) * 2004-12-22 2013-05-08 诺维信北美公司 具有葡糖淀粉酶活性的多肽以及编码该多肽的多核苷酸
NZ561009A (en) 2005-03-16 2009-07-31 Novozymes As Recombinant expression of defensins in filamentous fungi
AU2006226729B2 (en) 2005-03-22 2012-02-16 Novozymes A/S Polypeptides and nucleic acids encoding same
CN101253263B (zh) 2005-04-27 2014-07-02 诺维信股份有限公司 具有内切葡聚糖酶活性的多肽和编码该多肽的多核苷酸
CA2620125C (en) 2005-08-26 2013-08-20 Novozymes A/S Polypeptides having antimicrobial activity and polynucleotides encoding same
EP2385110A3 (en) 2005-09-30 2011-11-16 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
WO2007045248A1 (en) 2005-10-17 2007-04-26 Novozymes A/S Use of fungal mutants for expression of antibodies
US8262646B2 (en) * 2006-01-20 2012-09-11 Lensar, Inc. System and method for providing the shaped structural weakening of the human lens with a laser
BRPI0708949B1 (pt) 2006-03-20 2017-04-04 Novozymes As métodos para degradar ou converter um material celulósico, para produzir uma susbtância, e para produzir um polipeptídeo tendo atividade endoglucanase, e, célula microbiana recombinante
US8063267B2 (en) 2006-03-30 2011-11-22 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
CN103451164A (zh) 2006-07-14 2013-12-18 诺维信股份有限公司 用于产生具有生物学活性的分泌型多肽的方法
US8940502B2 (en) 2006-07-14 2015-01-27 Novozymes, Inc. Nucleic acid constructs and methods of making protein
DK2046819T3 (da) 2006-07-21 2015-06-22 Novozymes Inc Fremgangsmåder til forøgelse af secernering af polypeptider med biologisk aktivitet
CN103540562A (zh) 2006-11-30 2014-01-29 诺维信公司 重组宿主细胞中的脱氧核糖核酸酶表达
EP2505651A3 (en) 2006-12-10 2013-01-09 Dyadic International, Inc. Isolated fungus with reduced protease activity
PL2069490T5 (pl) * 2006-12-21 2018-09-28 Basf Enzymes Llc Amylazy i glukoamylazy, kwasy nukleinowe kodujące te związki oraz sposoby wytwarzania tych związków oraz stosowania ich
JP5643083B2 (ja) 2007-03-26 2014-12-17 ノボザイムス アクティーゼルスカブ ハフニア・フィターゼ
DE102007016139A1 (de) 2007-03-30 2008-10-02 Jenabios Gmbh Verfahren zur regioselektiven Oxygenierung von N-Heterozyklen
CN101835801B (zh) 2007-08-08 2014-09-10 诺维信生物制药丹麦公司 转铁蛋白变体和偶联物
JP5769142B2 (ja) * 2007-09-04 2015-08-26 独立行政法人酒類総合研究所 ピヒア属酵母において異種タンパク質を高分泌させる方法
CA2736661A1 (en) 2007-09-07 2009-03-12 Dyadic International, Inc. Novel fungal enzymes
EP2193195B1 (en) 2007-09-18 2014-12-17 Novozymes A/S Polypeptides having tyrosinase activity and polynucleotides encoding same
EP2215224B1 (en) 2007-11-27 2013-10-16 Novozymes A/S Polypeptides having alpha-glucuronidase activity and polynucleotides encoding same
WO2009073709A1 (en) 2007-12-06 2009-06-11 Novozymes A/S Polypeptides having acetylxylan esterase activity and polynucleotides encoding same
EP2235173A2 (en) 2007-12-19 2010-10-06 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CN102292444A (zh) 2008-11-20 2011-12-21 诺维信股份有限公司 具有淀粉分解增强活性的多肽和编码该多肽的多核苷酸
EP2373788A1 (en) 2008-12-04 2011-10-12 Novozymes Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US20110296557A1 (en) 2008-12-12 2011-12-01 Novozymes, Inc. Polypeptides Having Lipase Activity And Polynucleotides Encoding Same
US9493759B2 (en) 2008-12-12 2016-11-15 Novozymes, Inc. Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same
WO2010074972A1 (en) 2008-12-15 2010-07-01 Novozymes, Inc. Polypeptides having catalase activity and polynucleotides encoding same
CA2746757A1 (en) 2008-12-16 2010-07-08 Novozymes, Inc. Polypeptides having alpha-mannosidase activity and polynucleotides encoding same
WO2010074955A1 (en) 2008-12-16 2010-07-01 Novozymes, Inc. Polypeptides having carboxypeptidase activity and polynucleotides encoding same
US8426158B2 (en) 2008-12-19 2013-04-23 Novozymes, Inc. Methods for increasing enzymatic hydrolysis of cellulosic material in the presence of a peroxidase
CN102325889A (zh) 2008-12-19 2012-01-18 诺维信股份有限公司 增加纤维素材料水解的方法
CN102325879A (zh) 2008-12-19 2012-01-18 诺维信股份有限公司 在纤维二糖脱氢酶存在下增加纤维素材料水解的方法
US8338121B2 (en) 2008-12-19 2012-12-25 Novozymes, Inc. Methods for determining cellulolytic enhancing activity of a polypeptide
KR20110104539A (ko) 2008-12-23 2011-09-22 대니스코 에이/에스 자일라나제 활성을 갖는 폴리펩타이드
ES2558698T3 (es) 2009-01-21 2016-02-08 Novozymes A/S Polipéptidos con actividad de esterasa y ácidos nucleicos que codifican los mismos
EP2391715A1 (en) 2009-01-28 2011-12-07 Novozymes Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
WO2010088447A1 (en) 2009-01-30 2010-08-05 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
US8629324B2 (en) 2009-01-30 2014-01-14 Novozymes, Inc. Polypeptides having expansin activity and polynucleotides encoding same
WO2010091221A1 (en) 2009-02-06 2010-08-12 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
JP2012516878A (ja) 2009-02-06 2012-07-26 ノボザイムス バイオファーマ デーコー アクティーゼルスカブ 精製プロセス
KR101722961B1 (ko) 2009-02-11 2017-04-04 알부메딕스 에이/에스 알부민 변이체 및 접합체
WO2010106068A1 (en) 2009-03-17 2010-09-23 Novozymes A/S Polypeptides having tyrosinase activity and polynucleotides encoding same
CA2752007A1 (en) 2009-03-24 2010-09-30 Novozymes A/S Polypeptides having acetyl xylan esterase activity and polynucleotides encoding same
EP2248893A1 (en) 2009-05-06 2010-11-10 Novozymes A/S DFPase Enzymes from Octopus Vulgaris
BRPI1011597B1 (pt) 2009-05-29 2019-08-20 Novozymes, Inc. Métodos para degradar um material celulósico, para produzir um produto de fermentação, e para fermentar um material celulósico, e, composição de enzima
WO2010141325A1 (en) 2009-06-02 2010-12-09 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
WO2010151787A1 (en) 2009-06-26 2010-12-29 Novozymes North America, Inc. Heat-stable carbonic anhydrases and their use
WO2011005867A1 (en) 2009-07-07 2011-01-13 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity activity and polynucleotides encoding same
MX2012001060A (es) 2009-07-24 2012-03-14 Novozymes As Carbohidrato-oxidasas.
WO2011014458A1 (en) 2009-07-28 2011-02-03 Novozymes, Inc. Polypeptides having phytase activity and polynucleotides encoding same
WO2011015633A1 (en) 2009-08-07 2011-02-10 Novozymes A/S Method of producing a sweet protein
US8409830B2 (en) 2009-08-21 2013-04-02 Novozymes A/S Polypeptides having isoamylase activity and methods of use
CA2772695A1 (en) 2009-09-01 2011-03-10 Novozymes, Inc. Methods for improving malic acid production in filamentous fungi
WO2011035027A2 (en) 2009-09-17 2011-03-24 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2478095A1 (en) 2009-09-18 2012-07-25 Novozymes Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
CN102648277B (zh) 2009-09-25 2015-05-20 诺维信公司 蛋白酶变体的用途
WO2011036263A1 (en) 2009-09-25 2011-03-31 Novozymes A/S Subtilase variants
DK2483403T3 (en) 2009-09-29 2018-02-12 Novozymes Inc POLYPEPTIDES WITH XYLANASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM
MX2012003473A (es) 2009-09-29 2012-05-22 Novozymes Inc Polipeptidos que tienen actividad celulitica mejorada y polinucleotidos que codifican para los mismos.
WO2011041504A1 (en) 2009-09-30 2011-04-07 Novozymes, Inc. Polypeptides derived from thermoascus crustaceus having cellulolytic enhancing activity and polynucleotides encoding same
EP2483402A1 (en) 2009-09-30 2012-08-08 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2011050037A1 (en) 2009-10-23 2011-04-28 Novozymes, Inc. Cellobiohydrolase variants and polynucleotides encoding same
WO2011059740A1 (en) 2009-10-29 2011-05-19 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
CN102947442B (zh) 2009-11-06 2016-03-09 诺维信股份有限公司 用于糖化纤维素材料的组合物
CN104694517B (zh) 2009-11-06 2019-06-28 诺维信股份有限公司 具有木聚糖酶活性的多肽和编码该多肽的多核苷酸
US9267125B2 (en) 2009-11-06 2016-02-23 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
WO2011066560A1 (en) 2009-11-30 2011-06-03 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
MX2012006096A (es) 2009-11-30 2012-07-03 Novozymes North America Inc Polipeptidos que tienen actividad glucoamilasa y polinucleotidos que codifican para los mismos.
ES2534067T3 (es) 2009-12-01 2015-04-17 Novozymes A/S Polipéptidos que tienen actividad de glucoamilasa y polinucleótidos que codifican los mismos
WO2011067349A1 (en) 2009-12-03 2011-06-09 Novozymes A/S Variants of a polypeptide with lipolytic activity and improved stability
CN102753023A (zh) 2009-12-09 2012-10-24 诺维信公司 产生gh8木聚糖酶变体的方法
MX350399B (es) 2009-12-18 2017-09-06 Novozymes Inc Metodos para producir polipeptidos en mutantes de trichoderma deficientes en proteasa.
EP2501792A2 (en) 2009-12-29 2012-09-26 Novozymes A/S Gh61 polypeptides having detergency enhancing effect
US20120270267A1 (en) 2010-01-04 2012-10-25 Novozymes A/S Alpha-Amylases
WO2011104284A1 (en) 2010-02-25 2011-09-01 Novozymes A/S Polypeptides having antimicrobial activity
CA2791353A1 (en) 2010-03-03 2011-09-09 Novozymes, Inc. Xylanase variants and polynucleotides encoding same
CN102918151B (zh) 2010-03-31 2015-09-09 诺维信股份有限公司 纤维二糖水解酶变体及编码其的多核苷酸
MX338068B (es) 2010-04-14 2016-04-01 Novozymes As Polipeptidos que tienen actividad de glucoamilasa y polinucleotidos que codifican los mismos.
EP2576606B1 (en) 2010-06-04 2014-12-10 Novozymes, Inc. C4 dicarboxylic acid production in filamentous fungi
US8835604B2 (en) 2010-06-12 2014-09-16 Adenium Biotech Aos Antimicrobial peptide variants and polynucleotides encoding same
US8497103B2 (en) 2010-06-21 2013-07-30 Novozymes, Inc. Methods for C4-dicarboxylic acid production in filamentous fungi
MX2012014627A (es) 2010-06-21 2013-02-21 Novozymes Inc Polipeptidos derivados de aspergillus aculeatus con actividad transportadora de acido dicarboxilico c4 y polinucleotidos que los codifican.
WO2011161206A1 (en) 2010-06-25 2011-12-29 Novozymes A/S Polynucleotides having leader sequence function
EP2588604B1 (en) 2010-06-30 2016-06-29 Novozymes, Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
CN103459600B (zh) 2010-07-01 2016-10-19 帝斯曼知识产权资产管理有限公司 用于生产感兴趣的化合物的方法
US9394555B2 (en) 2010-08-12 2016-07-19 Novozymes, Inc. Compositions comprising a polypeptide having cellulolytic enhancing activity and a dioxy compound and uses thereof
WO2012025577A1 (en) 2010-08-24 2012-03-01 Novozymes A/S Heat-stable persephonella carbonic anhydrases and their use
WO2012030844A1 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
US9303074B2 (en) 2010-08-30 2016-04-05 Novoyzmes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US20130212746A1 (en) 2010-08-30 2013-08-15 Novoyzmes A/S Polypeptides Having Hemicellulolytic Activity And Polynucleotides Encoding Same
US9187742B2 (en) 2010-08-30 2015-11-17 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
US8624082B2 (en) 2010-08-30 2014-01-07 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
US8629325B2 (en) 2010-08-30 2014-01-14 Novozymes A/S Polypeptides having beta-glucosidase activity and polynucleotides encoding same
MX2013003237A (es) 2010-09-30 2013-05-30 Novozymes Inc Variantes de polipeptidos que tienen actividad potenciadora celulolitica y polinucleotidos que codifican a los mismos.
DK2622068T3 (en) 2010-09-30 2016-10-17 Novozymes Inc Variants of polypeptides having cellulolytic enhancing ACTIVITY AND POLYNUCLEOTIDES ENCODING THEM
DK3023492T3 (en) 2010-10-01 2018-03-05 Novozymes Inc Beta-glucosidase variants and polynucleotides encoding them
CA2809916A1 (en) 2010-10-01 2012-04-05 Novozymes A/S Polypeptides having endopeptidase activity and polynucleotides encoding same
WO2012058293A1 (en) 2010-10-26 2012-05-03 Novozymes North America, Inc. Methods of saccharifying sugarcane trash
EP2632943A1 (en) 2010-10-29 2013-09-04 Novozymes A/S Polypeptides having succinyl-coa:aceto acetate transferase activity and polynucleotides encoding same
JP2013544083A (ja) 2010-10-29 2013-12-12 ノボザイムス アクティーゼルスカブ 組み換えｎ−プロパノール及びイソプロパノール生産
ES2541492T3 (es) 2010-11-02 2015-07-21 Novozymes, Inc. Métodos para pretratar material celulósico con polipéptido GH61
US9212354B2 (en) 2010-11-04 2015-12-15 Novozymes Inc. Polypeptides having cellobiohydrolase activitiy and polynucleotides encoding same
EP2637515B1 (en) 2010-11-08 2017-09-06 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
CN103298932B (zh) 2010-11-08 2016-08-10 诺维信公司 具有葡糖淀粉酶活性的多肽和编码该多肽的多核苷酸
BR112013009026A2 (pt) 2010-11-12 2016-07-12 Novozymes Inc polipeptídeo isolado, célula hospedeira recombinante, métodos para produzir um polipeptídeo, um mutante de uma célula precursora, uma proteína, e um produto de fermentação, para inibir a expressão de um polipeptídeo, para degradar ou converter um material celulósico, e método para fermentar um material celulósico, planta transgênica, parte de planta ou célula de planta, molécula de rna inibidora de filamento duplo, polinucleotídeo isolado, e, formulação de caldo integral ou composição de cultura de célula
RU2013126882A (ru) 2010-11-12 2014-12-20 Новозимс А/С Полипептиды, обладающие активностью фосфолипазы с, и полинуклеотиды, кодирующие их
DK2640833T3 (en) 2010-11-18 2016-11-28 Novozymes Inc Chimeric polypeptides having cellulolytic enhancing ACTIVITY AND POLYNUCLEOTIDES ENCODING THEM
CN105420267A (zh) 2010-11-30 2016-03-23 诺维信股份有限公司 用于在真菌细胞中表达基因的启动子
EP2649188A1 (en) 2010-12-06 2013-10-16 Novozymes North America, Inc. Methods of hydrolyzing oligomers in hemicellulosic liquor
AU2011338504B2 (en) 2010-12-07 2015-01-22 Vnomics Corp. System and method for measuring and reducing vehicle fuel waste
US9284588B2 (en) 2010-12-16 2016-03-15 Novozymes, Inc. Promoters for expressing genes in a fungal cell
WO2012103350A1 (en) 2011-01-26 2012-08-02 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
US9353363B2 (en) 2011-01-26 2016-05-31 Novozymes A/S Glycoside hydrolases from thermophilic fungi
CN103517986B (zh) 2011-01-26 2016-12-07 诺维信公司 具有纤维二糖水解酶活性的多肽及编码该多肽的多核苷酸
WO2012103322A1 (en) 2011-01-26 2012-08-02 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
DK2668266T3 (en) 2011-01-26 2018-03-26 Novozymes Inc POLYPEPTIDES WITH CELLOBIO HYDROASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM
US9434972B2 (en) 2011-01-31 2016-09-06 Novozymes North America, Inc. Processes for enzymatic refining of pretreated cellulosic material for saccharification
CN103384678B (zh) 2011-02-23 2017-01-18 诺维信股份有限公司 具有纤维素水解增强活性的多肽及其编码多核苷酸
EP2678427A2 (en) 2011-02-23 2014-01-01 DuPont Nutrition Biosciences ApS Method for producing recombinant enzymes capable of hydrolysing chlorophyll or a chlorophyll derivative
EP2681307A1 (en) 2011-02-28 2014-01-08 Novozymes, Inc. Microorganism for c4-dicarboxylic acid production
US9150842B2 (en) 2011-03-09 2015-10-06 Novozymes A/S Methods of increasing the cellulolytic enhancing activity of a polypeptide
US9409958B2 (en) 2011-03-10 2016-08-09 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CN103596970A (zh) 2011-03-11 2014-02-19 帝斯曼知识产权资产管理有限公司 载体-宿主系统
WO2012130120A1 (en) 2011-03-25 2012-10-04 Novozymes A/S Method for degrading or converting cellulosic material
WO2012135659A2 (en) 2011-03-31 2012-10-04 Novozymes A/S Methods for enhancing the degradation or conversion of cellulosic material
EP2691519A1 (en) 2011-03-31 2014-02-05 Novozymes, Inc. Cellulose binding domain variants and polynucleotides encoding same
CN103649308A (zh) 2011-04-28 2014-03-19 诺维信股份有限公司 具有内切葡聚糖酶活性的多肽和编码该多肽的多核苷酸
US9624518B2 (en) 2011-04-29 2017-04-18 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
US8993286B2 (en) 2011-05-19 2015-03-31 Novozymes, Inc. Methods for enhancing the degradation of cellulosic material with chitin binding proteins
WO2012159007A1 (en) 2011-05-19 2012-11-22 Novozymes, Inc. Methods for enhancing the degradation of cellulosic material with chitin binding proteins
EP2527448A1 (en) 2011-05-23 2012-11-28 Novozymes A/S Simultaneous site-specific integrations of multiple gene-copies in filamentous fungi
EP2527432A1 (en) 2011-05-23 2012-11-28 Novozymes A/S Bi-directional cytosine deaminase-encoding selection marker
EP2723858B1 (en) 2011-06-24 2017-04-12 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
WO2013001087A2 (en) 2011-06-30 2013-01-03 Novozymes A/S Method for screening alpha-amylases
ES2834102T3 (es) 2011-06-30 2021-06-16 Novozymes As Variantes de alfa-amilasa
BR112014000143B1 (pt) 2011-07-06 2021-04-06 Novozymes A/S Variante de alfa-amilase, polinucleotídeo isolado, vetor de expressão, célula hospedeira, métodos de produzir uma variante de alfa-amilase, para produzir um produto de fermentação a partir de um material contendo amido, e, para a produção um derivado de amido enzimaticamente modificado
WO2013010783A1 (en) 2011-07-15 2013-01-24 Novozymes A/S Lipase variants and polynucleotides encoding same
EP2734633B1 (en) 2011-07-22 2019-05-01 Novozymes North America, Inc. Processes for pretreating cellulosic material and improving hydrolysis thereof
DK3382016T3 (da) 2011-08-04 2019-11-18 Novozymes Inc Polypeptider med xylanaseaktivitet og polynukleotider, der koder for dem
BR112014002405A2 (pt) 2011-08-04 2017-04-04 Novozymes As polopeptídeo e polinucleotídeo isolados, composição, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, planta transgênica, parte da planta ou célula de planta, métodos para produzir um polipeptídeo e uma proteína, e, processos para degradar um material celulóssico, para produzir um produto de fermentação, e para fermentar um material celulósico
EP2742060B1 (en) 2011-08-10 2017-03-01 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021060A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021059A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021065A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021062A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021064A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
US9382559B2 (en) 2011-08-10 2016-07-05 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
EP2744898A1 (en) 2011-08-15 2014-06-25 Novozymes A/S Polypeptides having cellulase activity and polynucleotides encoding same
US20140295027A1 (en) 2011-08-19 2014-10-02 Novozymes A/S Polypeptides Having Protease Activity
CN103917649A (zh) 2011-08-19 2014-07-09 诺维信股份有限公司 用于生产c4-二羧酸的重组微生物
EP2748321A2 (en) 2011-08-24 2014-07-02 Novozymes, Inc. Methods for obtaining positive transformants of a filamentous fungal host cell
US9493790B2 (en) 2011-08-24 2016-11-15 Novozymes, Inc. Methods for producing multiple recombinant polypeptides in a filamentous fungal host cell
CN103890169A (zh) 2011-08-24 2014-06-25 诺维信股份有限公司 烟曲霉纤维素分解酶组合物及其用途
BR112014004186B1 (pt) 2011-08-24 2020-12-15 Novozymes, Inc. Composição enzimática, célula hospedeira de fungo filamentoso recombinante, método para produzir uma composição enzimática, processos para degradar um material celulósico, para sintetizar um produto de fermentação, e, para fermentar um material celulósico
CA2846690A1 (en) 2011-08-26 2013-03-07 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
EA201490568A1 (ru) 2011-09-06 2014-06-30 Новозимс А/С Варианты глюкоамилазы и кодирующие их полинуклеотиды
CA2847236A1 (en) 2011-09-09 2013-03-14 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
US9670510B2 (en) 2011-09-13 2017-06-06 Novozymes A/S Methods of hydrolyzing and fermenting cellulosic material
WO2013043910A1 (en) 2011-09-20 2013-03-28 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
ES2628190T3 (es) 2011-09-22 2017-08-02 Novozymes A/S Polipéptidos con actividad de proteasa y polinucleótidos que codifican los mismos
BR112014007651A2 (pt) 2011-09-30 2017-04-11 Novozymes Inc polipeptídeo quimérico isolado, polinucleotídeo isolado, métodos para produzir um polipeptídeo quimérico e um produto de fermentação, para degradar ou converter um material celulósico, e para fermentar um material celulósico, planta, parte de planta ou célula de planta transgênica, e, formulação de caldo inteiro ou composição de cultura de células
US8728788B1 (en) 2011-09-30 2014-05-20 Novozymes A/S Dehydrogenase variants and polynucleotides encoding same
CA2850070A1 (en) 2011-09-30 2013-04-04 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
EA201490649A1 (ru) 2011-10-11 2014-07-30 Новозимс А/С Варианты глюкоамилазы и кодирующие их полинуклеотиды
EP2748316B1 (en) 2011-10-17 2018-12-19 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
HUE039835T2 (hu) 2011-10-17 2019-02-28 Novozymes As Alfa-amiláz variánsok és az azokat kódoló polinukleotidok
DK2773656T3 (da) 2011-10-31 2019-09-09 Novozymes Inc Polypeptider med cellulolyseforbedrende aktivitet og polynukleotider, som koder for dem
EP3409769A1 (en) 2011-11-18 2018-12-05 Novozymes A/S Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same
DK3219794T3 (da) 2011-11-21 2019-12-16 Novozymes Inc GH61-polypeptidvarianter og polynukleotider, som koder for dem
WO2013075644A1 (en) 2011-11-22 2013-05-30 Novozymes, Inc. Polypeptides having beta-xylosidase activity and polynucleotides encoding same
RU2619051C2 (ru) 2011-11-25 2017-05-11 Новозимс А/С Полипептиды с лизоцимной активностью и полинуклеотиды, кодирующие их
BR112014012417A2 (pt) 2011-12-01 2017-06-06 Novozymes Inc polipeptídeo e polinucleotídeo isolados, célula hospedeira recombinante, métodos para a produção de um polipeptídeo, de um mutante de uma célula de origem, e de uma proteína, e para a inibição da expressão de um polipeptídeo, planta transgênica, parte da planta ou célula de planta, molécula de rna, processos para degradar ou converter um material celulósico ou contendo xilano, para produzir um produto de fermentação, e de fermentação de um material celulósico ou contendo xilano, e, formulação de caldo integral ou composição de cultura de células
US9404093B2 (en) 2011-12-02 2016-08-02 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013079531A2 (en) 2011-12-02 2013-06-06 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
EP3272862A1 (en) 2011-12-16 2018-01-24 Novozymes, Inc. Polypeptides having laccase activity and polynucleotides encoding same
BR112014014697A2 (pt) 2011-12-19 2020-10-27 Novozymes, Inc. polipeptídeo isolado, composição, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, métodos para produzir um polipeptídeo e uma proteína, para gerar oxigênio molecular, e para remover peróxido de hidrogênio do tecido, processos para degradar ou converter um material celulósico, e para produzir um produto de fermentação, e, formulação de caldo integral ou composição de cultura de células
BR112014015228B1 (pt) 2011-12-20 2022-07-05 Novozymes, Inc. Variante de celobiohidrolase genitora, processos para degradação ou conversão de um material celulósico, para produção de um produto de fermentação, e de fermentação de um material celulósico, formulação de caldo inteiro ou composição de cultura celular, e, célula hospedeira microbiana transgênica
US10174301B2 (en) 2011-12-28 2019-01-08 Novozymes A/S Methods for improving the nutritional value of the animal feed using a protease
BR112014017919A2 (pt) 2012-01-26 2017-06-27 Novozymes As uso de um poliptídeo variante, composição, polinucleotídeo isolado, constructo de ácido nucleico ou vetor de expressão, célula hospedeira de expressão recombinante, métodos de produção do pilipeptídeo, para melhoria do valor nutricional de uma ração animal, e para o tratamento de proteínas, planta, parte de planta ou célula de planta transgênica, aditivo de ração animal, ração animal, e, composição de ração animal ou detergente
MX353896B (es) 2012-02-03 2018-02-01 Procter & Gamble Composiciones y metodos para el tratamiento de superficies con lipasas.
EP2809779B1 (en) 2012-02-03 2017-09-13 Novozymes A/S Lipase variants and polynucleotides encoding same
BR112014018876A2 (pt) 2012-02-20 2017-07-04 Novozymes As polipeptídeo isolado com atividade endoglicanase, composição, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, e, método de produção de um polipeptídeo
CN107988181A (zh) 2012-04-02 2018-05-04 诺维信公司 脂肪酶变体以及编码其的多核苷酸
EP2841569A2 (en) 2012-04-23 2015-03-04 Novozymes A/S Polypeptides having alpha-glucuronidase activity and polynucleotides encoding same
US9394556B2 (en) 2012-04-23 2016-07-19 Novozymes A/S Polypeptides having glucuronyl esterase activity and polynucleotides encoding same
CA2868308A1 (en) 2012-04-27 2013-10-31 Novozymes, Inc. Gh61 polypeptide variants and polynucleotides encoding same
DK2847308T3 (en) 2012-05-07 2017-10-23 Novozymes As Polypeptides with xanthan-degrading activity and polynucleotides encoding them
CN109234250A (zh) 2012-05-31 2019-01-18 诺维信公司 具有有机磷水解酶活性的多肽
CN104395454B (zh) 2012-05-31 2021-11-30 诺维信公司 改善的真菌选择
AU2013279440B2 (en) 2012-06-20 2016-10-06 Novozymes A/S Use of polypeptides having protease activity in animal feed and detergents
WO2014009473A1 (en) 2012-07-12 2014-01-16 Novozymes A/S Polypeptides having lipase activity and polynucleotides encoding same
AU2013291936B2 (en) 2012-07-19 2019-01-17 Dsm Ip Assets B.V. AgsE-deficient strain
CN104603269A (zh) 2012-08-17 2015-05-06 诺维信公司 用于在丝状真菌菌株中共沉默基因表达的方法及其应用
US9828595B2 (en) 2012-08-17 2017-11-28 Novozymes A/S Thermostable asparaginase variants and polynucleotides encoding same
EP2888361A1 (en) 2012-08-22 2015-07-01 Novozymes A/S Metalloprotease from exiguobacterium
US9315791B2 (en) 2012-08-22 2016-04-19 Novozymes A/S Metalloproteases from alicyclobacillus
DK2893012T3 (en) 2012-09-05 2018-12-03 Novozymes As Polypeptides with protease activity
JP5971661B2 (ja) * 2012-09-19 2016-08-17 国立大学法人 東京大学 神経活動依存的プロモータ活性を有するｄｎａ、及びこれを含むベクター
CN104685052A (zh) 2012-09-19 2015-06-03 诺维信股份有限公司 用于增强纤维素材料的降解或转化的方法
US10035996B2 (en) 2012-10-08 2018-07-31 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CN104704116B (zh) 2012-10-12 2018-09-28 诺维信公司 具有过氧合酶活性的多肽
WO2014056920A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
CN104704115B (zh) 2012-10-12 2018-11-02 诺维信公司 具有过氧合酶活性的多肽
CN104718287B (zh) 2012-10-12 2018-02-06 诺维信公司 具有过氧合酶活性的多肽
WO2014056916A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
EP2906689B1 (en) 2012-10-12 2018-12-12 Novozymes A/S Polypeptides having peroxygenase activity
US9499801B2 (en) 2012-10-12 2016-11-22 Novozymes A/S Polypeptides having peroxygenase activity
US20150275194A1 (en) 2012-10-24 2015-10-01 Novozymes A/S Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same
WO2014076232A2 (en) 2012-11-19 2014-05-22 Novozymes A/S Isopropanol production by recombinant hosts using an hmg-coa intermediate
WO2014086706A1 (en) 2012-12-07 2014-06-12 Novozymes A/S Method for generating site-specific mutations in filamentous fungi
RU2015126866A (ru) 2012-12-11 2017-01-19 Новозимс А/С Полипептиды, обладающие активностью фосфолипазы с, и полинуклеотиды, кодирующие их
WO2014093835A1 (en) 2012-12-14 2014-06-19 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CA2894261C (en) 2012-12-17 2022-01-04 Novozymes A/S Alpha-amylases and polynucleotides encoding same
US20150337280A1 (en) 2012-12-19 2015-11-26 Novozymes A/S Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same
EP2934177B1 (en) 2012-12-21 2017-10-25 Novozymes A/S Polypeptides having protease activiy and polynucleotides encoding same
WO2014101753A1 (en) 2012-12-24 2014-07-03 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
US9902946B2 (en) 2013-01-03 2018-02-27 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
EP2951296A2 (en) 2013-02-04 2015-12-09 DSM IP Assets B.V. Carbohydrate degrading polypeptide and uses thereof
AU2014214032A1 (en) 2013-02-06 2015-07-09 Novozymes A/S Use of polypeptides having protease activity in animal feed
CN110628749A (zh) 2013-03-08 2019-12-31 诺维信公司 纤维二糖水解酶变体和编码它们的多核苷酸
WO2014145768A2 (en) 2013-03-15 2014-09-18 Bp Corporation North America Inc. Use of non-fungal 5' utrs in filamentous fungi
EP3533866A1 (en) 2013-03-21 2019-09-04 Novozymes A/S Polypeptides having phospholipase a activity and polynucleotides encoding same
US9631164B2 (en) 2013-03-21 2017-04-25 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
CN105378050A (zh) 2013-04-18 2016-03-02 诺维信公司 具有蛋白酶活性的多肽和编码它们的多核苷酸
CA2904022C (en) 2013-04-30 2022-04-19 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
WO2014177541A2 (en) 2013-04-30 2014-11-06 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
CN105283546B (zh) 2013-05-10 2025-08-12 国投生物科技投资有限公司 具有木聚糖酶活性的多肽以及对其进行编码的多核苷酸
AR096270A1 (es) 2013-05-14 2015-12-16 Novozymes As Composiciones detergentes
US20160083703A1 (en) 2013-05-17 2016-03-24 Novozymes A/S Polypeptides having alpha amylase activity
US10538751B2 (en) 2013-06-06 2020-01-21 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
WO2014202622A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202620A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202624A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202621A1 (en) 2013-06-20 2014-12-24 Dsm Ip Assets B.V. Carbohydrate degrading polypeptide and uses thereof
US20160152925A1 (en) 2013-07-04 2016-06-02 Novozymes A/S Polypeptides Having Anti-Redeposition Effect and Polynucleotides Encoding Same
EP3019603A1 (en) 2013-07-09 2016-05-18 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
HUE040545T2 (hu) 2013-07-17 2019-03-28 Novozymes As Pullulanáz kimérák és az azokat kódoló polinukleotidok
CA2917690A1 (en) 2013-07-26 2015-01-29 Biomethodes Novel variant trichoderma reesei endoglucanases
CN104342419B (zh) * 2013-08-06 2017-03-08 上海康地恩生物科技有限公司 一种来源于黑葡萄穗霉的葡糖淀粉酶
WO2015022429A1 (en) 2013-08-15 2015-02-19 Novozymes A/S Polypeptides having beta-1,3-galactanase activity and polynucleotides encoding same
WO2015059133A1 (en) 2013-10-22 2015-04-30 Novozymes A/S Cellobiose dehydrogenase variants and polynucleotides encoding same
EP3060666B1 (en) 2013-10-25 2020-09-30 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
US20170166939A1 (en) 2013-11-26 2017-06-15 Novozymes A/S Enzyme Compositions and Uses Thereof
EP2876156A1 (en) 2013-11-26 2015-05-27 Commissariat A L'energie Atomique Et Aux Energies Alternatives New enzymes and method for preparing hydroxylated L-lysine or L-ornithine and analogs thereof
CN105793418A (zh) 2013-11-29 2016-07-20 诺维信公司 过氧合酶变体
DK3077517T3 (en) 2013-12-02 2019-02-11 Dsm Ip Assets Bv ISSTRUCTURING PROTEIN
WO2015085920A1 (en) 2013-12-11 2015-06-18 Novozymes A/S Cutinase variants and polynucleotides encoding same
EP2886656A1 (en) 2013-12-18 2015-06-24 Commissariat A L'energie Atomique Et Aux Energies Alternatives New enzyme and method for preparing 4-hydroxyl benzyl alcohol and derivatives thereof
EP3083954B1 (en) 2013-12-20 2018-09-26 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
EP3415624B1 (en) 2014-01-22 2021-08-04 Novozymes A/S Pullulanase variants and polynucleotides encoding same
US20170073890A1 (en) 2014-03-05 2017-03-16 Novozymes A/S Compositions and Methods for Functionalizing and Linking Materials
EP3114272A1 (en) 2014-03-05 2017-01-11 Novozymes A/S Compositions and methods for improving properties of cellulosic textile materials with xyloglucan endotransglycosylase
US20160348035A1 (en) 2014-03-05 2016-12-01 Novozymes A/S Compositions and Methods for Improving Properties of Non-Cellulosic Textile Materials with Xyloglucan Endotransglycosylase
BR112016020374A2 (pt) 2014-03-05 2018-01-23 Novozymes As formulação, e, métodos para potenciar o crescimento de plantas e para formular um ou mais agentes agricolamente benéficos
EP3113609B1 (en) 2014-03-05 2019-07-31 Novozymes A/S Methods for improving post-harvest properties of agricultural crops
US10155935B2 (en) 2014-03-12 2018-12-18 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
US20170015950A1 (en) 2014-04-01 2017-01-19 Novozymes A/S Polypeptides having alpha amylase activity
EP3129478B1 (en) 2014-04-10 2019-03-27 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
BR112016023188A2 (pt) 2014-04-11 2018-01-16 Novozymes As uso de um polipeptídeo, composição detergente, métodos de lavagem para a lavagem de um item e de produção do polipeptídeo, polipeptídeo isolado, construção de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, e, formulação de caldo inteiro ou composição de cultura de células
CN106715465B (zh) 2014-04-15 2021-10-08 诺维信公司 具有脂肪酶活性的多肽和编码它们的多核苷酸
WO2015177153A1 (en) 2014-05-19 2015-11-26 Dsm Ip Assets B.V. Proline-specific endoprotease
WO2015177152A1 (en) 2014-05-19 2015-11-26 Dsm Ip Assets B.V. Proline-specific endoprotease
WO2015177171A1 (en) 2014-05-19 2015-11-26 Dsm Ip Assets B.V. Proline-specific endoprotease
EP3760713A3 (en) 2014-05-27 2021-03-31 Novozymes A/S Lipase variants and polynucleotides encoding same
CA2950273C (en) 2014-05-30 2022-06-21 Novozymes A/S Variants of gh family 11 xylanase and polynucleotides encoding same
EP3152315B1 (en) 2014-06-06 2018-08-15 Novozymes A/S Enzyme compositions and uses thereof
WO2015200659A1 (en) 2014-06-25 2015-12-30 Novozymes A/S Xylanase variants and polynucleotides encoding same
EP3183339A1 (en) 2014-08-20 2017-06-28 Novozymes A/S Xyloglucan endotransglycosylase variants and polynucleotides encoding same
EP3594335B1 (en) 2014-09-05 2024-05-01 Novozymes A/S Carbohydrate binding module variants and polynucleotides encoding same
WO2016062875A2 (en) 2014-10-23 2016-04-28 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
BR112017009320A2 (pt) 2014-11-04 2017-12-19 Novozymes As ração animal ou aditivo de ração animal, uso de ração animal ou aditivo de ração animal, e, métodos para preparação de uma ração animal, para melhoria do valor nutricional de uma ração animal, para tratamento de proteínas aumento da digestibilidade e/ou solubilidade da proteína, para melhoria de um ou mais parâmetros de desempenho em um animal e para produção de um polipeptídeo.
US10287562B2 (en) 2014-11-20 2019-05-14 Novoszymes A/S Alicyclobacillus variants and polynucleotides encoding same
EP3227438B1 (en) 2014-12-02 2024-03-27 Novozymes A/S Laccase variants and polynucleotides encoding same
EP4067485A3 (en) 2014-12-05 2023-01-04 Novozymes A/S Lipase variants and polynucleotides encoding same
WO2016096996A1 (en) 2014-12-16 2016-06-23 Novozymes A/S Polypeptides having n-acetyl glucosamine oxidase activity
MX383142B (es) 2014-12-19 2025-03-13 Novozymes As Composiciones que comprenden polipéptidos que tienen actividad xilanasa y polipéptidos que tienen actividad arabinofuranosidasa.
WO2016100910A1 (en) 2014-12-19 2016-06-23 Novozymes A/S Recombinant host cells for the production of 3-hydroxypropionic acid
DK3739045T3 (da) 2015-02-24 2024-10-21 Novozymes As Cellobiohydrolasevarianter og polynukleotider, som koder for dem
WO2016138303A1 (en) 2015-02-27 2016-09-01 Novozymes A/S Mutant host cells for the production of 3-hydroxypropionic acid
WO2016145084A1 (en) 2015-03-09 2016-09-15 Novozymes A/S Methods of introducing multiple expression constructs into a eukaryotic cell
CN107667177A (zh) 2015-04-07 2018-02-06 诺维信公司 用于选择具有增强活性的酶的方法
CN107864658A (zh) 2015-04-07 2018-03-30 诺维信公司 用于选择具有脂肪酶活性的酶的方法
AR104205A1 (es) 2015-04-09 2017-07-05 Dsm Ip Assets Bv Fosfolipasa c
CN116676293A (zh) 2015-05-27 2023-09-01 国投生物科技投资有限公司 具有纤维二糖水解酶活性的多肽以及对其进行编码的多核苷酸
EP3302076A1 (en) 2015-06-02 2018-04-11 DSM IP Assets B.V. Use of ice structuring protein afp19 expressed in filamentous fungal strains for preparing food
CN108012543B (zh) 2015-06-16 2022-01-04 诺维信公司 具有脂肪酶活性的多肽和编码它们的多核苷酸
US10676727B2 (en) 2015-06-18 2020-06-09 Novozymes A/S Polypeptides having trehalase activity and the use thereof in process of producing fermentation products
EP3313990A4 (en) 2015-06-26 2019-01-23 Novozymes A/S BIO-finishing system
BR112017028063B1 (pt) 2015-06-26 2022-05-17 Novozymes A/S Método para produção de um extrato de café
WO2016207373A1 (en) 2015-06-26 2016-12-29 Novozymes A/S Polypeptides having peroxygenase activity
AU2016286612B2 (en) 2015-07-02 2021-01-28 Novozymes A/S Animal feed compositions and uses thereof
CN107969136B (zh) 2015-07-06 2021-12-21 诺维信公司 脂肪酶变体以及编码它们的多核苷酸
US20180216089A1 (en) 2015-07-24 2018-08-02 Novozymes, Inc. Polypeptides Having Beta-Xylosidase Activity And Polynucleotides Encoding Same
BR112018001041A2 (pt) 2015-07-24 2018-09-11 Novozymes Inc polipeptídeo isolado, composição, formulação de caldo inteiro ou composição de cultura de células, célula hospedeira recombinante, métodos para produção de um polipeptídeo e para produção de uma proteína, planta, parte de planta ou célula de planta transgênica, e, processos para degradação de um material celulósico ou hemicelulósico, para produção de um produto de fermentação e para fermentação de um material celulósico ou hemicelulósico.
EP3330375A1 (en) 2015-07-29 2018-06-06 Abengoa Bioenergía Nuevas Tecnologías, S. A. Expression of recombinant beta-xylosidase enzymes
US20180265902A1 (en) 2015-08-24 2018-09-20 Novozymes A/S Beta-Alanine Aminotransferases For The Production of 3-Hydroxypropionic Acid
CN108350443B (zh) 2015-09-17 2022-06-28 诺维信公司 具有黄原胶降解活性的多肽以及编码它们的多核苷酸
CN108350044B (zh) 2015-09-22 2022-05-24 诺维信公司 具有纤维二糖水解酶活性的多肽以及对其进行编码的多核苷酸
WO2017050652A1 (en) 2015-09-25 2017-03-30 Dsm Ip Assets B.V. Asparaginase
CN116064474A (zh) 2015-10-07 2023-05-05 诺维信公司 多肽
US10479981B2 (en) 2015-10-14 2019-11-19 Novozymes A/S DNase variants
US20180171318A1 (en) 2015-10-14 2018-06-21 Novozymes A/S Polypeptides Having Protease Activity and Polynucleotides Encoding Same
US10494685B2 (en) 2015-10-14 2019-12-03 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
WO2017070219A1 (en) 2015-10-20 2017-04-27 Novozymes A/S Lytic polysaccharide monooxygenase (lpmo) variants and polynucleotides encoding same
WO2017075426A1 (en) 2015-10-30 2017-05-04 Novozymes A/S Polynucleotide constructs for in vitro and in vivo expression
CN108473974A (zh) 2015-11-24 2018-08-31 诺维信公司 具有蛋白酶活性的多肽以及编码其的多核苷酸
CN108431217B (zh) 2015-12-01 2022-06-21 诺维信公司 用于产生脂肪酶的方法
MX2018006610A (es) 2015-12-02 2019-05-27 Inst Nat De La Rech Agronomique Inra Nuevos peptidos que tienen actividad antimicrobiana y nueva enzima capaces de convertir un residuo de configuracion l en un aminoacido de configuracion d en un peptido.
JP7146637B2 (ja) 2015-12-22 2022-10-04 アルブミディクス リミティド 改善されたタンパク質発現株
EP3394243A1 (en) 2015-12-22 2018-10-31 Albumedix Ltd. Improved protein expression strains
JP7626576B2 (ja) 2015-12-30 2025-02-07 ノボザイムス アクティーゼルスカブ 酵素変異体およびこれをコードするポリヌクレオチド
MX2018008051A (es) 2016-01-29 2018-08-23 Novozymes As Variantes de beta-glucanasa y polinucleotidos que las codifican.
US11685911B2 (en) 2016-02-16 2023-06-27 Monaghan Mushroom S Group Fungal polypeptides having lysozyme activity
EP3420104A1 (en) 2016-02-23 2019-01-02 Novozymes A/S Improved next-generation sequencing
US10738293B2 (en) 2016-03-02 2020-08-11 Novozymes A/S Cellobiohydrolase variants and polynucleotides encoding same
DK3433358T3 (da) 2016-03-24 2022-09-26 Novozymes As Cellobiohydrolasevarianter og polynukleotider, der koder for dem
EP3440207A1 (en) 2016-04-07 2019-02-13 Novozymes A/S Methods for selecting enzymes having protease activity
CN108779155A (zh) 2016-04-19 2018-11-09 诺维信公司 RlmA灭活的丝状真菌宿主细胞
EP3693449A1 (en) 2016-04-29 2020-08-12 Novozymes A/S Detergent compositions and uses thereof
EP3452497B1 (en) 2016-05-03 2021-02-17 Novozymes A/S Alpha-amylase variants and polynucleotides encoding the same
EP3455352B1 (en) 2016-05-09 2026-03-18 Novozymes A/S Variant polypeptides with improved performance and use of the same
EP3246401A1 (en) 2016-05-20 2017-11-22 Commissariat À L'Énergie Atomique Et Aux Énergies Alternatives New fatty acid decarboxylase and its uses
CN109312321A (zh) 2016-05-24 2019-02-05 诺维信公司 包含具有半乳聚糖酶活性的多肽和具有β-半乳糖苷酶活性的多肽的组合物
WO2017202997A1 (en) 2016-05-24 2017-11-30 Novozymes A/S Compositions comprising polypeptides having galactanase activity and polypeptides having beta-galactosidase activity
BR112018073875A2 (pt) 2016-05-24 2019-02-26 Novozymes As polipeptídeo isolado, composição, grânulo, aditivo de ração animal, formulação líquida, ração animal, métodos para liberar galactose de material à base de planta, para melhorar um ou mais parâmetros de desempenho de um animal e o valor nutricional de uma ração animal, para preparar uma ração animal e para produzir o polipeptídeo, uso, polinucleotídeo, construto de ácido nucleico ou vetor de expressão, e, célula hospedeira recombinante.
DK3462904T3 (da) 2016-05-24 2025-01-02 Novozymes As Polypeptider med alfa-galactosidaseaktivitet og polynukleotider, der koder for samme
WO2017205535A1 (en) 2016-05-27 2017-11-30 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2017211803A1 (en) 2016-06-07 2017-12-14 Novozymes A/S Co-expression of heterologous polypeptides to increase yield
WO2017211930A1 (en) 2016-06-10 2017-12-14 Dsm Ip Assets B.V. Mutant lipase and use thereof
EP3263699B1 (en) 2016-06-30 2020-07-01 Fornia BioSolutions, Inc. Novel phytases and uses thereof
WO2018002261A1 (en) 2016-07-01 2018-01-04 Novozymes A/S Detergent compositions
WO2018007435A1 (en) 2016-07-05 2018-01-11 Novozymes A/S Pectate lyase variants and polynucleotides encoding same
US20190185847A1 (en) 2016-07-06 2019-06-20 Novozymes A/S Improving a Microorganism by CRISPR-Inhibition
WO2018007573A1 (en) 2016-07-08 2018-01-11 Novozymes A/S Detergent compositions with galactanase
BR112019000125A2 (pt) 2016-07-08 2019-07-09 Novozymes As grânulo, polipeptídeo isolado, composição, aditivo de ração animal, ração animal peletizada, métodos de aprimoramento de um ou mais parâmetros de desempenho de um animal, de preparação de uma ração animal, para aprimorar o valor nutricional de uma ração animal, de solubilização de xilana a partir do material à base de planta e de produção do polipeptídeo, polinucleotídeo, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, e, uso do grânulo
CN109415710A (zh) 2016-07-08 2019-03-01 诺维信公司 木聚糖酶变体和对其编码的多核苷酸
ES3000090T3 (en) 2016-07-13 2025-02-27 Procter & Gamble Bacillus cibi dnase variants and uses thereof
EP3485008B1 (en) 2016-07-18 2024-01-31 Novozymes A/S Lipase variants, polynucleotides encoding same and the use thereof
WO2018017792A1 (en) 2016-07-20 2018-01-25 Novozymes A/S Heat-stable metagenomic carbonic anhydrases and their use
MX2019000743A (es) 2016-07-21 2019-05-20 Novozymes As Variantes de serinproteasa y polinucleotidos que las codifican.
CA3028875A1 (en) 2016-07-21 2018-01-25 Novozymes A/S Serine protease variants and polynucleotides encoding same
WO2018015444A1 (en) 2016-07-22 2018-01-25 Novozymes A/S Crispr-cas9 genome editing with multiple guide rnas in filamentous fungi
CN109476714A (zh) 2016-07-22 2019-03-15 诺维信公司 改善的丝状真菌宿主
WO2018026868A1 (en) 2016-08-01 2018-02-08 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
US10988747B2 (en) 2016-08-24 2021-04-27 Henkel Ag & Co. Kgaa Detergent composition comprising GH9 endoglucanase variants I
CA3031609A1 (en) 2016-08-24 2018-03-01 Novozymes A/S Gh9 endoglucanase variants and polynucleotides encoding same
KR102483218B1 (ko) 2016-08-24 2023-01-02 헨켈 아게 운트 코. 카게아아 크산탄 리아제 변이체 i을 포함하는 세제 조성물
US11512300B2 (en) 2016-08-24 2022-11-29 Novozymes A/S Xanthan lyase variants and polynucleotides encoding same
WO2018050666A1 (en) 2016-09-15 2018-03-22 Novozymes A/S Genomic integration of dna fragments in fungal host cells
EP3532592A1 (en) 2016-10-25 2019-09-04 Novozymes A/S Detergent compositions
US20210284991A1 (en) 2016-11-21 2021-09-16 Novozymes A/S Yeast Cell Extract Assisted Construction of DNA Molecules
AU2017380488B2 (en) 2016-12-21 2023-09-14 Novozymes A/S Polypeptides having lysozyme activity, polynucleotides encoding same and uses and compositions thereof
CN110234747B (zh) 2017-02-01 2021-11-09 宝洁公司 包含淀粉酶变体的清洁组合物
BR112019015943A2 (pt) 2017-02-01 2020-04-07 Novozymes A/S variantes de alfa-amilase
CN110431224A (zh) 2017-03-13 2019-11-08 帝斯曼知识产权资产管理有限公司 锌双核簇转录调控因子缺陷型菌株
WO2018167153A1 (en) 2017-03-17 2018-09-20 Novozymes A/S Improved filamentous fungal host cell
WO2018172155A1 (en) 2017-03-23 2018-09-27 Novozymes A/S Improved filamentous fungal host cells
WO2018177938A1 (en) 2017-03-31 2018-10-04 Novozymes A/S Polypeptides having dnase activity
WO2018177203A1 (en) 2017-03-31 2018-10-04 Novozymes A/S Polypeptides having dnase activity
US11053483B2 (en) 2017-03-31 2021-07-06 Novozymes A/S Polypeptides having DNase activity
EP3601551A1 (en) 2017-03-31 2020-02-05 Novozymes A/S Polypeptides having rnase activity
US20200109352A1 (en) 2017-04-04 2020-04-09 Novozymes A/S Polypeptide compositions and uses thereof
US20200109354A1 (en) 2017-04-04 2020-04-09 Novozymes A/S Polypeptides
WO2018185181A1 (en) 2017-04-04 2018-10-11 Novozymes A/S Glycosyl hydrolases
CN110651048A (zh) 2017-04-11 2020-01-03 诺维信公司 葡糖淀粉酶变体和编码它们的多核苷酸
US11078445B2 (en) 2017-05-05 2021-08-03 Novozymes A/S Compositions comprising lipase and sulfite
WO2018206535A1 (en) 2017-05-08 2018-11-15 Novozymes A/S Carbohydrate-binding domain and polynucleotides encoding the same
EP3401385A1 (en) 2017-05-08 2018-11-14 Henkel AG & Co. KGaA Detergent composition comprising polypeptide comprising carbohydrate-binding domain
WO2018224035A1 (en) 2017-06-09 2018-12-13 Novozymes A/S Polypeptide, use and method for hydrolysing protein
JP7282693B2 (ja) 2017-06-20 2023-05-29 アルブミディクス リミティド 改良されたタンパク質発現株
WO2018234465A1 (en) 2017-06-22 2018-12-27 Novozymes A/S Xylanase variants and polynucleotides encoding same
ES2908190T3 (es) 2017-06-28 2022-04-28 Novozymes As Polipéptidos con actividad de trehalasa y polinucleótidos que los codifican
WO2019023222A1 (en) 2017-07-24 2019-01-31 Novozymes A/S GH5 AND GH30 IN WET MILLING
US10081800B1 (en) 2017-08-03 2018-09-25 Fornia Biosolutions, Inc. Lactonase enzymes and methods of using same
CA3070281A1 (en) 2017-08-08 2019-02-14 Novozymes A/S Polypeptides having trehalase activity and the use thereof in process of producing fermentation products
US11624059B2 (en) 2017-08-24 2023-04-11 Henkel Ag & Co. Kgaa Detergent compositions comprising GH9 endoglucanase variants II
US11525128B2 (en) 2017-08-24 2022-12-13 Novozymes A/S GH9 endoglucanase variants and polynucleotides encoding same
US20210130744A1 (en) 2017-08-24 2021-05-06 Henkel Ag & Co. Kgaa Detergent composition comprising xanthan lyase variants ii
WO2019038057A1 (en) 2017-08-24 2019-02-28 Novozymes A/S VARIANTS OF XANTHANE LYASE AND POLYNUCLEOTIDES ENCODING THE SAME
WO2019046703A1 (en) 2017-09-01 2019-03-07 Novozymes A/S METHODS OF ENHANCING GENOME EDITION IN FUNGI
AR112955A1 (es) 2017-09-01 2020-01-08 Novozymes As Aditivos de alimento animal que comprenden polipéptidos que tienen actividad proteasa y usos de los mismos
CN111050565A (zh) 2017-09-01 2020-04-21 诺维信公司 包含具有蛋白酶活性的多肽的动物饲料添加剂及其用途
WO2019063614A1 (en) 2017-09-26 2019-04-04 Bunge Global Innovation, Llc. ENZYMATIC REMOVAL OF CHLOROPHYLLIC SUBSTRATES FROM TRIACYLGLYCEROL OILS
JP7317811B2 (ja) 2017-09-27 2023-07-31 ノボザイムス アクティーゼルスカブ リパーゼ変異体及びかかるリパーゼ変異体を含むマイクロカプセル組成物
US11634673B2 (en) * 2017-09-29 2023-04-25 Dupont Nutrition Biosciences Aps Production of brewer's wort having increase fermentable sugars for fermentation
WO2019068715A1 (en) 2017-10-02 2019-04-11 Novozymes A/S POLYPEPTIDES HAVING MANNANASE ACTIVITY AND POLYNUCLEOTIDES ENCODING THESE POLYPEPTIDES
US11746310B2 (en) 2017-10-02 2023-09-05 Novozymes A/S Polypeptides having mannanase activity and polynucleotides encoding same
MX2020004145A (es) 2017-10-27 2020-08-03 Novozymes As Variantes de desoxirribonucleasa (dnasa).
PL3476935T3 (pl) 2017-10-27 2022-03-28 The Procter & Gamble Company Kompozycje detergentowe zawierające odmiany polipeptydowe
DE102017125560A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine iii enthalten
DE102017125558A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine i enthalten
DE102017125559A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine ii enthalten
EP3707252A1 (en) 2017-11-10 2020-09-16 Novozymes A/S Temperature-sensitive cas9 protein
WO2019096903A1 (en) 2017-11-20 2019-05-23 Novozymes A/S New galactanases (ec 3.2.1.89) for use in soy processing
EP3485734A1 (en) 2017-11-21 2019-05-22 Technische Universität München Method for preparing food products comprising rye
EP3488854A1 (en) 2017-11-22 2019-05-29 Technische Universität München Method for preparing xyloglucan-oligosaccharides
CN111670248A (zh) 2017-12-04 2020-09-15 诺维信公司 脂肪酶变体以及编码其的多核苷酸
EP3502242A1 (en) 2017-12-20 2019-06-26 Technische Universität München New xylanase with improved thermostability and increased enzyme activity on arabinoxylan
US20210017544A1 (en) 2017-12-22 2021-01-21 Novozymes A/S Counter-Selection by Inhibition of Conditionally Essential Genes
KR101992345B1 (ko) * 2017-12-29 2019-09-27 (주)메디톡스 프로모터 폴리뉴클레오티드, 신호 폴리펩티드 및 그의 용도
WO2019154952A1 (en) 2018-02-08 2019-08-15 Novozymes A/S Lipase variants and compositions thereof
EP3749761A1 (en) 2018-02-08 2020-12-16 Novozymes A/S Lipases, lipase variants and compositions thereof
EP3775222B1 (en) 2018-03-26 2024-01-03 Novozymes A/S Fungal chaperone proteins
CN112105729B (zh) 2018-04-09 2024-05-14 诺维信公司 具有α-淀粉酶活性的多肽以及编码它们的多核苷酸
EP3781680A1 (en) 2018-04-19 2021-02-24 Novozymes A/S Stabilized cellulase variants
EP3781679A1 (en) 2018-04-19 2021-02-24 Novozymes A/S Stabilized cellulase variants
KR20210013097A (ko) 2018-05-18 2021-02-03 디에스엠 아이피 어셋츠 비.브이. 돌연변이체 리파아제 및 이의 용도
WO2019219903A2 (en) 2018-05-18 2019-11-21 Dsm Ip Assets B.V. Mutant lipase and use thereof
WO2020002575A1 (en) 2018-06-28 2020-01-02 Novozymes A/S Polypeptides having pectin lyase activity and polynucleotides encoding same
US20210301285A1 (en) 2018-08-02 2021-09-30 Novozymes A/S Preparation of Combinatorial Libraries of DNA Constructs
US11473076B2 (en) 2018-08-31 2022-10-18 Novozymes A/S Animal feed additives and compositions comprising an S8 serine protease
EP3861008A1 (en) 2018-10-03 2021-08-11 Novozymes A/S Polypeptides having alpha-mannan degrading activity and polynucleotides encoding same
EP3864136A1 (en) 2018-10-09 2021-08-18 Novozymes A/S Modified filamentous fungal host cell
CN113039278A (zh) 2018-10-31 2021-06-25 诺维信公司 通过指导的内切核酸酶和单链寡核苷酸进行基因组编辑
CN120040562A (zh) 2018-11-28 2025-05-27 诺维信公司 改善的丝状真菌宿主细胞
JP7609774B2 (ja) 2018-11-28 2025-01-07 ノボザイムス アクティーゼルスカブ 修飾された糸状菌宿主細胞
CN113302293A (zh) 2018-12-12 2021-08-24 诺维信公司 具有木聚糖酶活性的多肽以及编码这些多肽的多核苷酸
CN109652417B (zh) * 2018-12-17 2021-07-27 江南大学 一种构建高效枯草芽孢杆菌启动子的方法
DK3898985T5 (da) 2018-12-21 2024-08-05 Novozymes As Proteinekspression i tandem
CN113366103A (zh) 2018-12-21 2021-09-07 诺维信公司 具有肽聚糖降解活性的多肽以及编码其的多核苷酸
EP3908654A1 (en) 2019-01-11 2021-11-17 River Stone Biotech ApS Recombinant host cells with improved production of l-dopa, dopamine, (s)-norcoclaurine or derivatives thereof
WO2020161354A1 (en) 2019-02-08 2020-08-13 Pili Recombinant host cells to produce anthraquinone derivatives
WO2020173817A1 (en) 2019-02-28 2020-09-03 Novozymes A/S Calcite binding proteins
EP3737751A1 (en) 2019-03-21 2020-11-18 Fornia BioSolutions, Inc. Additional phytase variants and methods
US11098265B2 (en) 2019-03-27 2021-08-24 Bunge Global Innovation, Llc Silica adsorbent treatment for removal of chlorophyll derivatives from triacylglycerol-based oils
MX2021011981A (es) 2019-04-03 2021-11-03 Novozymes As Polipeptidos que tienen actividad de beta-glucanasa, polinucleotidos que los codifican y usos de los mismos en composiciones de limpieza y de detergente.
EP3953462A1 (en) 2019-04-10 2022-02-16 Novozymes A/S Polypeptide variants
CN113795576A (zh) 2019-04-12 2021-12-14 诺维信公司 稳定化的糖苷水解酶变体
WO2020229191A1 (en) 2019-05-15 2020-11-19 Novozymes A/S Temperature-sensitive rna-guided endonuclease
CA3141928A1 (en) 2019-05-27 2020-12-03 Octarine Bio Ivs Genetically modified host cells producing glycosylated cannabinoids
MX2021015382A (es) 2019-06-24 2022-01-24 Procter & Gamble Composiciones de limpieza que comprenden variantes de amilasa.
EP3987022A1 (en) 2019-06-24 2022-04-27 Novozymes A/S Alpha-amylase variants
EP3990629A1 (en) 2019-06-25 2022-05-04 Novozymes A/S Counter-selection by inhibition of conditionally essential genes
EP3994255A1 (en) 2019-07-02 2022-05-11 Novozymes A/S Lipase variants and compositions thereof
EP4004211A1 (en) 2019-07-25 2022-06-01 Novozymes A/S Filamentous fungal expression system
CN114555777A (zh) 2019-07-26 2022-05-27 诺维信公司 经修饰的丝状真菌宿主细胞
WO2021048172A2 (en) 2019-09-09 2021-03-18 River Stone Biotech Aps Delivery vehicle for in situ delivering of pharmaceutical agents
CA3152952A1 (en) 2019-09-16 2021-03-25 Novozymes A/S Polypeptides having beta-glucanase activity and polynucleotides encoding same
US20220340843A1 (en) 2019-10-03 2022-10-27 Novozymes A/S Polypeptides comprising at least two carbohydrate binding domains
WO2021122867A2 (en) 2019-12-19 2021-06-24 Novozymes A/S Xylanase variants and polynucleotides encoding same
WO2021123307A2 (en) 2019-12-20 2021-06-24 Novozymes A/S Polypeptides having proteolytic activity and use thereof
BR112022014573A2 (pt) 2020-01-24 2022-10-04 Novozymes As Mutantes de uma célula fúngica filamentosa com produtividade aumentada na produção de um polipeptídeo
JP7731360B2 (ja) 2020-01-31 2025-08-29 ノボザイムス アクティーゼルスカブ マンナナーゼバリアント及びそれをコードするポリヌクレオチド
US12497606B2 (en) 2020-01-31 2025-12-16 Novozymes A/S Mannanase variants and polynucleotides encoding same
US20230142991A1 (en) 2020-02-10 2023-05-11 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
US20240228996A1 (en) 2020-02-10 2024-07-11 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
US20230235367A1 (en) 2020-02-10 2023-07-27 Novozymes A/S Process for producing ethanol from raw starch using alpha-amylase variants
EP4110909A1 (en) 2020-02-26 2023-01-04 Novozymes A/S Polypeptide variants
WO2021183622A1 (en) 2020-03-12 2021-09-16 Novozymes A/S Crispr-aid using catalytically inactive rna-guided endonuclease
EP3892708A1 (en) 2020-04-06 2021-10-13 Henkel AG & Co. KGaA Cleaning compositions comprising dispersin variants
US20230143128A1 (en) 2020-04-08 2023-05-11 Novozymes A/S Carbohydrate binding module variants
WO2021214059A1 (en) 2020-04-21 2021-10-28 Novozymes A/S Cleaning compositions comprising polypeptides having fructan degrading activity
BR112023003468A2 (pt) 2020-08-25 2023-04-11 Novozymes As Variantes de uma xiloglucanase da família 44
US20230265408A1 (en) 2020-08-28 2023-08-24 Novozymes A/S Protease variants with improved solubility
EP4229189A1 (en) 2020-10-13 2023-08-23 Novozymes A/S Glycosyltransferase variants for improved protein production
BR112023008326A2 (pt) 2020-10-29 2023-12-12 Novozymes As Variantes de lipase e composições compreendendo tais variantes de lipase
WO2022090564A1 (en) 2020-11-02 2022-05-05 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
CN116583534A (zh) 2020-11-02 2023-08-11 诺维信公司 前导肽和编码其的多核苷酸
EP4026900A3 (en) 2020-12-17 2022-10-05 Fornia BioSolutions, Inc. Xylanase variants and methods
AR124921A1 (es) 2021-02-18 2023-05-17 Novozymes As Polipéptidos inactivos que contienen hemo
EP4305146A1 (en) 2021-03-12 2024-01-17 Novozymes A/S Polypeptide variants
EP4060036A1 (en) 2021-03-15 2022-09-21 Novozymes A/S Polypeptide variants
CN116615536A (zh) 2021-03-15 2023-08-18 宝洁公司 含有多肽变体的清洁组合物
US20240060061A1 (en) 2021-03-15 2024-02-22 Novozymes A/S Dnase variants
US20240150805A1 (en) 2021-05-07 2024-05-09 River Stone Biotech Aps Glycosylated Opioids
BR112023024706A2 (pt) 2021-05-27 2024-02-15 Novozymes As Reguladores da transcrição e polinucleotídeos que os codificam
EP4359518A1 (en) 2021-06-23 2024-05-01 Novozymes A/S Alpha-amylase polypeptides
WO2023006699A1 (en) 2021-07-30 2023-02-02 Københavns Universitet Cells and method for producing isoprenoid molecules with canonical and non-canonical structures
AU2023376563A1 (en) 2022-11-08 2025-05-01 River Stone Biotech Aps Genetically modified benzylisoquinoline alkaloid-producing host cells with modified efflux transporter gene expression
CN116675748A (zh) * 2023-04-28 2023-09-01 河南农业大学 一种假禾谷镰孢分泌的植物免疫激活蛋白FpCDP1及其应用
WO2026017657A1 (fr) 2024-07-15 2026-01-22 Pili Production d'acide p-aminobenzoïque par un microorganisme recombinant

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
DE3854249T2 (de) 1987-08-28 1996-02-29 Novonordisk As Rekombinante Humicola-Lipase und Verfahren zur Herstellung von rekombinanten Humicola-Lipasen.
DE69129988T2 (de) 1990-09-13 1999-03-18 Novo Nordisk A/S, Bagsvaerd Lipase-varianten
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
GB9316883D0 (en) * 1993-08-13 1993-09-29 Univ Leeds Production of heterologous peptices
WO1995033836A1 (en) 1994-06-03 1995-12-14 Novo Nordisk Biotech, Inc. Phosphonyldipeptides useful in the treatment of cardiovascular diseases
ATE294871T1 (de) * 1994-06-30 2005-05-15 Novozymes Biotech Inc Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren
EP2295581A3 (en) 1996-01-19 2011-05-04 Novozymes Biotech, Inc. Morphological mutants of filamentous fungi
CN1190673A (zh) * 1996-04-29 1998-08-19 中国科学院微生物研究所 丝状真菌中独立复制的表达载体及表达系统
AU4424597A (en) 1996-09-13 1998-04-02 Novo Nordisk Biotech, Inc. Cells having dna insertion mutations which produce altered amounts of a polypeptide
ATE195140T1 (de) 1996-12-20 2000-08-15 Novo Nordisk As Peniophora phytase

Also Published As

Publication number Publication date
AU4025700A (en) 2000-10-09
JP2002539793A (ja) 2002-11-26
EP2278016A1 (en) 2011-01-26
CN1526820A (zh) 2004-09-08
EP2278016B1 (en) 2012-09-26
CN1536089A (zh) 2004-10-13
CN1526820B (zh) 2010-05-26
WO2000056900A3 (en) 2002-01-31
DK2278016T3 (da) 2012-11-26
JP2013121360A (ja) 2013-06-20
CN1526821A (zh) 2004-09-08
JP5264825B2 (ja) 2013-08-14
CN1940067A (zh) 2007-04-04
JP2010227108A (ja) 2010-10-14
JP2013121361A (ja) 2013-06-20
WO2000056900A2 (en) 2000-09-28
CN100510096C (zh) 2009-07-08
EP1194572A2 (en) 2002-04-10
CN1367838A (zh) 2002-09-04
CN100532561C (zh) 2009-08-26
CN100482801C (zh) 2009-04-29

Similar Documents

Publication Publication Date Title
JP4620253B2 (ja) 菌類細胞中で遺伝子を発現させるためのプロモーター
CN1425068B (zh) 在制备多肽的方法中有效的真菌转录激活因子
US7919275B2 (en) Oxaloacetate hydrolase deficient fungal host cells
JP4563585B2 (ja) ポリペプチドの生成方法において有用な菌類転写活性化因子
JP2011101651A (ja) オキサロ酢酸ヒドロラーゼ欠陥真菌宿主細胞
JP2009543560A (ja) 真菌細胞中の遺伝子発現を上昇させる方法
US8426164B2 (en) Fungal transcriptional activator useful in methods for producing polypeptides
EP1078081B1 (en) Methods for producing heterologous polypeptides in trichothecene-deficient filamentous fungal mutant cells
EP1616580B1 (en) Alpha-amylase transcription factor
JP4927281B2 (ja) 共通翻訳開始配列を用いるポリペプチドの産生方法
EP1078080A1 (en) Methods for producing polypeptides in filamentous fungal mutant cells
US6692940B2 (en) Promoters for expressing genes in a fungal cell
CN1969041B (zh) 用于生产多肽的信号肽
EP1032683B1 (en) Polypeptides having 5-aminolevulinic acid synthase activity and nucleic acids encoding same

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070314

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070314

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20091117

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100216

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100223

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100512

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100810

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100830

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20100928

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20101028

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20131105

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees