JP4323571B2 - 光学装置 - Google Patents
光学装置 Download PDFInfo
- Publication number
- JP4323571B2 JP4323571B2 JP53276398A JP53276398A JP4323571B2 JP 4323571 B2 JP4323571 B2 JP 4323571B2 JP 53276398 A JP53276398 A JP 53276398A JP 53276398 A JP53276398 A JP 53276398A JP 4323571 B2 JP4323571 B2 JP 4323571B2
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- Prior art keywords
- flow
- reflector
- electromagnetic radiation
- particle
- particle flow
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
- G01N15/1436—Optical arrangements the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B5/00—Optical elements other than lenses
- G02B5/04—Prisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
- G01N2015/1452—Adjustment of focus; Alignment
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6463—Optics
- G01N2021/6469—Cavity, e.g. ellipsoid
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Optics & Photonics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Optical Elements Other Than Lenses (AREA)
- Polarising Elements (AREA)
- Glass Compositions (AREA)
- Eye Examination Apparatus (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Surgical Instruments (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ31416997 | 1997-01-31 | ||
| NZ314169 | 1997-01-31 | ||
| PCT/NZ1998/000009 WO1998034094A1 (en) | 1997-01-31 | 1998-02-02 | Optical apparatus |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007006458A Division JP4727595B2 (ja) | 1997-01-31 | 2007-01-15 | 光学装置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001509266A JP2001509266A (ja) | 2001-07-10 |
| JP2001509266A5 JP2001509266A5 (enExample) | 2005-10-06 |
| JP4323571B2 true JP4323571B2 (ja) | 2009-09-02 |
Family
ID=19926129
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP53276398A Expired - Lifetime JP4323571B2 (ja) | 1997-01-31 | 1998-02-02 | 光学装置 |
| JP2007006458A Expired - Lifetime JP4727595B2 (ja) | 1997-01-31 | 2007-01-15 | 光学装置 |
| JP2011058447A Expired - Lifetime JP5512579B2 (ja) | 1997-01-31 | 2011-03-16 | 光学装置 |
| JP2014042303A Expired - Lifetime JP6016830B2 (ja) | 1997-01-31 | 2014-03-05 | 光学装置 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007006458A Expired - Lifetime JP4727595B2 (ja) | 1997-01-31 | 2007-01-15 | 光学装置 |
| JP2011058447A Expired - Lifetime JP5512579B2 (ja) | 1997-01-31 | 2011-03-16 | 光学装置 |
| JP2014042303A Expired - Lifetime JP6016830B2 (ja) | 1997-01-31 | 2014-03-05 | 光学装置 |
Country Status (8)
| Country | Link |
|---|---|
| US (8) | US6819411B1 (enExample) |
| EP (4) | EP1017987B1 (enExample) |
| JP (4) | JP4323571B2 (enExample) |
| AT (1) | ATE298084T1 (enExample) |
| AU (1) | AU752985B2 (enExample) |
| CA (1) | CA2279574C (enExample) |
| DE (1) | DE69830598T2 (enExample) |
| WO (1) | WO1998034094A1 (enExample) |
Families Citing this family (109)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1017987B1 (en) | 1997-01-31 | 2005-06-15 | The Horticulture And Food Research Institute Of New Zealand Limited | Optical apparatus and method |
| US6149867A (en) | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
| US6071689A (en) | 1997-12-31 | 2000-06-06 | Xy, Inc. | System for improving yield of sexed embryos in mammals |
| DK1100534T3 (da) | 1998-07-30 | 2008-03-10 | Xy Inc | System til ikke-kirurgisk kunstig insemination af heste |
| US7208265B1 (en) | 1999-11-24 | 2007-04-24 | Xy, Inc. | Method of cryopreserving selected sperm cells |
| CA2408939C (en) | 2000-05-09 | 2011-11-08 | Xy, Inc. | High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa |
| AU2001236517A2 (en) | 2000-10-05 | 2002-04-15 | Xy, Inc. | System of hysteroscopic insemination of mares |
| US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
| AU2002220018A1 (en) | 2000-11-29 | 2002-06-11 | Colorado State University | System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations |
| WO2002092247A1 (en) * | 2001-05-17 | 2002-11-21 | Cytomation, Inc. | Flow cytometer with active automated optical alignment system |
| DE10202999B4 (de) * | 2002-01-26 | 2004-04-15 | Palas Gmbh Partikel- Und Lasermesstechnik | Verfahren und Vorrichtung zum Messen der Größenverteilung und Konzentration von Partikeln in einem Fluid |
| JP4595067B2 (ja) | 2002-08-01 | 2010-12-08 | エックスワイ,エルエルシー | 低圧精子細胞分離システム |
| US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
| US20050229046A1 (en) * | 2002-08-02 | 2005-10-13 | Matthias Marke | Evaluation of received useful information by the detection of error concealment |
| WO2004017041A2 (en) | 2002-08-15 | 2004-02-26 | Xy, Inc. | High resolution flow cytometer |
| US7169548B2 (en) | 2002-09-13 | 2007-01-30 | Xy, Inc. | Sperm cell processing and preservation systems |
| US6936828B2 (en) | 2003-02-14 | 2005-08-30 | Honeywell International Inc. | Particle detection system and method |
| ES2930062T3 (es) | 2003-03-28 | 2022-12-05 | Inguran Llc | Aparato para detectar el punto de rotura de un sistema de generación de gotitas |
| AU2004242121B2 (en) * | 2003-05-15 | 2010-06-24 | Xy, Llc. | Efficient haploid cell sorting for flow cytometer systems |
| FR2860869B1 (fr) * | 2003-10-10 | 2007-04-20 | Optis | Dispositif portable de mesure de l'intensite lumineuse d'un objet et utilisation d'un tel dispositif |
| JP2007531523A (ja) | 2004-03-29 | 2007-11-08 | モンサント テクノロジー エルエルシー | Xまたはy染色体担持豊富化集団に仕分けるための精子懸濁液 |
| AR049732A1 (es) | 2004-07-22 | 2006-08-30 | Monsanto Co | Proceso para enriquecer una poblacion de celulas de esperma |
| US7430046B2 (en) | 2004-07-30 | 2008-09-30 | Biovigilant Systems, Inc. | Pathogen and particle detector system and method |
| US7110192B2 (en) * | 2005-01-12 | 2006-09-19 | Dako Denmark A/S | System and method for a composite lens for a flow cytometer |
| DE102005031647A1 (de) * | 2005-07-06 | 2007-01-11 | Chromasens Gmbh | Beleuchtungsvorrichtung zur Dunkelfeldbeleuchtung für eine optische Testvorrichtung und Verfahren zum optischen Abtasten eines Objektes |
| US7738099B2 (en) | 2005-07-15 | 2010-06-15 | Biovigilant Systems, Inc. | Pathogen and particle detector system and method |
| US7618770B2 (en) | 2005-07-29 | 2009-11-17 | Xy, Inc. | Methods and apparatus for reducing protein content in sperm cell extenders |
| WO2007041458A2 (en) * | 2005-10-03 | 2007-04-12 | The Salk Institute For Biological Studies | Maximal-aperture reflecting objective |
| DE102005054184B4 (de) * | 2005-11-14 | 2020-10-29 | Carl Zeiss Microscopy Gmbh | Multispektrale Beleuchtungsvorrichtung und Messverfahren |
| US7671985B1 (en) * | 2006-03-13 | 2010-03-02 | Milan Milosevic | Device for small spot analysis using fiber optic interfaced spectrometers |
| CN101467306B (zh) * | 2006-04-24 | 2012-12-26 | 睿励科学仪器(上海)有限公司 | 光谱椭偏仪 |
| WO2008019130A2 (en) * | 2006-08-04 | 2008-02-14 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health | Wide-area fluorescence detection system for multi-photon microscopy |
| US20080055755A1 (en) * | 2006-08-31 | 2008-03-06 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Electromagnetic device and method |
| CN101236150B (zh) * | 2007-02-02 | 2012-09-05 | 深圳迈瑞生物医疗电子股份有限公司 | 用于基于流式细胞术的仪器的光电传感器及其照射单元 |
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| JP5546454B2 (ja) * | 2007-08-15 | 2014-07-09 | マルベルン インスツルメンツ リミテッド | 広幅分光計 |
| JP5252892B2 (ja) * | 2007-11-20 | 2013-07-31 | オリンパス株式会社 | 光学ユニット |
| US8628976B2 (en) | 2007-12-03 | 2014-01-14 | Azbil BioVigilant, Inc. | Method for the detection of biologic particle contamination |
| EP2232231A4 (en) * | 2007-12-04 | 2015-12-02 | Particle Measuring Syst | SYSTEMS AND METHODS FOR DETECTION OF NON-ORTHOGONAL PARTICLES |
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| PL2248073T3 (pl) * | 2008-02-05 | 2016-10-31 | Generator wzorca optycznego stosujący segmenty aksikonu | |
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| US8251887B2 (en) * | 2009-01-24 | 2012-08-28 | Xihe Li | Reproductive technology of low dose semen production and in vitro/in vitro fertilization in domestic animals |
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| EP2495682B1 (en) * | 2009-10-30 | 2018-07-25 | Fujitsu Frontech Limited | Illumination optical system of image capturing device |
| KR101739162B1 (ko) * | 2010-03-09 | 2017-05-23 | 베크만 컬터, 인코포레이티드 | 유세포 분석 시스템 및 방법에 대한 액적 지연 계산 |
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| US9625810B2 (en) * | 2011-03-16 | 2017-04-18 | Kla-Tencor Corporation | Source multiplexing illumination for mask inspection |
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| US9888990B2 (en) | 2012-06-06 | 2018-02-13 | Inguran, Llc | Methods for use of sex sorted semen to improve genetic management in swine |
| JP5841498B2 (ja) * | 2012-06-18 | 2016-01-13 | 国立大学法人東京工業大学 | 対象物検出装置 |
| CN103575632B (zh) * | 2012-08-09 | 2015-09-23 | 深圳开立生物医疗科技股份有限公司 | 一种鞘流装置及血液分析仪 |
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1998
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