BR112015013166A2 - dispositivo de interrogação óptica - Google Patents
dispositivo de interrogação ópticaInfo
- Publication number
- BR112015013166A2 BR112015013166A2 BR112015013166A BR112015013166A BR112015013166A2 BR 112015013166 A2 BR112015013166 A2 BR 112015013166A2 BR 112015013166 A BR112015013166 A BR 112015013166A BR 112015013166 A BR112015013166 A BR 112015013166A BR 112015013166 A2 BR112015013166 A2 BR 112015013166A2
- Authority
- BR
- Brazil
- Prior art keywords
- sample
- light
- excitation
- excitation light
- luminescent
- Prior art date
Links
- 230000003287 optical effect Effects 0.000 title abstract 4
- 230000005284 excitation Effects 0.000 abstract 8
- 238000004020 luminiscence type Methods 0.000 abstract 2
- 230000003595 spectral effect Effects 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/443—Emission spectrometry
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6445—Measuring fluorescence polarisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
- G01N21/763—Bioluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/10—Arrangements of light sources specially adapted for spectrometry or colorimetry
- G01J2003/102—Plural sources
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/021—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using plane or convex mirrors, parallel phase plates, or particular reflectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0213—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using attenuators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0216—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using light concentrators or collectors or condensers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0218—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
- G01N2021/6419—Excitation at two or more wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6463—Optics
- G01N2021/6471—Special filters, filter wheel
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6484—Optical fibres
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/061—Sources
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Microscoopes, Condenser (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
1/1 resumo dispositivo de interrogação óptica um dispositivo de interrogação para detectar luz luminescente produzida por analisados em uma amostra excitada por múltiplos feixes de luz de excitação cada tendo conteúdos espectrais individuais, compreendendo uma pluralidade de fontes de luz cada gerando um feixe de luz de excitação; pelo menos um detector para detectar a luz luminescente produzida pela amostra; e um conjunto óptico definindo percursos de luz de excitação distintos e fixos para cada dos feixes de luz de excitação a partir das fontes de luz para um local de excitação comum sobre a amostra e definindo um percurso de luz de luminescência compartilhada para a luz luminescente a partir do local de excitação sobre a amostra para pelo menos um detector, os percursos de luz de excitação e o percurso de luz de luminescência estando em um mesmo lado da amostra, o conjunto óptico incluindo óptica do lado de amostra projetando a luz de excitação em direção à amostra e coletando luz luminescente a partir da amostra.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261733653P | 2012-12-05 | 2012-12-05 | |
US201361813864P | 2013-04-19 | 2013-04-19 | |
PCT/IB2013/060686 WO2014087380A1 (en) | 2012-12-05 | 2013-12-05 | Optical interrogation device |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015013166A2 true BR112015013166A2 (pt) | 2017-07-11 |
Family
ID=50882881
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015013166A BR112015013166A2 (pt) | 2012-12-05 | 2013-12-05 | dispositivo de interrogação óptica |
Country Status (7)
Country | Link |
---|---|
US (1) | US10101274B2 (pt) |
EP (1) | EP2929308A4 (pt) |
JP (1) | JP6501714B2 (pt) |
CN (1) | CN105008878B (pt) |
BR (1) | BR112015013166A2 (pt) |
CA (1) | CA2862766C (pt) |
WO (1) | WO2014087380A1 (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
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JP6720526B2 (ja) * | 2015-12-25 | 2020-07-08 | 東洋紡株式会社 | 検査装置 |
EP3420338B1 (en) * | 2016-02-26 | 2023-05-03 | Single Technologies AB | Method and apparatus for high throughput imaging |
JP7008029B2 (ja) * | 2016-03-01 | 2022-01-25 | モレキュラー デバイシーズ, エルエルシー | 源自己蛍光を低減させ、均一性を改良するための散乱を伴う撮像システムおよび方法 |
KR20180051196A (ko) * | 2016-11-08 | 2018-05-16 | 삼성전자주식회사 | 분광기, 생체정보 측정 장치 및 방법 |
CN106353295A (zh) * | 2016-11-11 | 2017-01-25 | 中国科学院生物物理研究所 | 一种蛋白质热稳定分析仪 |
US11199449B1 (en) * | 2017-09-26 | 2021-12-14 | The United States Of America, As Represented By The Secretary Of The Navy | Automated noncontact method to discriminate whether cooling or heating is occurring |
SG11201912279RA (en) | 2018-03-29 | 2020-01-30 | Illumina Inc | Illumination for fluorescence imaging using objective lens |
CN108681056B (zh) * | 2018-06-26 | 2024-05-28 | 深圳市吉斯迪科技有限公司 | 面向活体的多波长偏振光生物医学显微成像装置 |
CN112423883A (zh) | 2018-07-12 | 2021-02-26 | 卢米耐克斯公司 | 用于进行可变样品制备和分析过程的系统和方法 |
CN110066723A (zh) * | 2019-05-05 | 2019-07-30 | 京东方科技集团股份有限公司 | 基因测序芯片、设备、制造方法 |
EP3736550A1 (en) * | 2019-05-10 | 2020-11-11 | X-Rite Switzerland GmbH | Illumination device for a spectrophotometer having integrated mixing optics, and method for illuminating a sample |
EP3770567B1 (de) * | 2019-07-23 | 2021-09-01 | Sick Ag | Optoelektronischer sensor |
EP4372100A1 (en) * | 2022-11-15 | 2024-05-22 | Stilla Technologies | Data analysis method for multiplex digital pcr using color-combination |
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DE102010010741A1 (de) | 2010-03-09 | 2011-09-15 | Beckman Coulter, Inc. | Lichtleitervorrichtung zum Abstrahlen und Empfangen von Licht, System, Verfahren und Computerprogrammprodukt |
CN102834711A (zh) | 2010-04-02 | 2012-12-19 | 3M创新有限公司 | 包括光学被分析物传感器和光学读取器的过滤系统 |
CN201785391U (zh) | 2010-08-27 | 2011-04-06 | 浙江大学 | 一种实时荧光定量pcr仪荧光信号检测装置 |
PT3270141T (pt) | 2011-03-08 | 2020-08-28 | Univ Laval | Dispositivo centrípeto fluídico |
CN103814289A (zh) | 2011-07-22 | 2014-05-21 | 比奥森西亚专利有限公司 | 用于发光免疫测定的读取器装置 |
WO2013092766A1 (en) | 2011-12-21 | 2013-06-27 | Imec | Optical fluorescence-based chemical and biochemical sensors and methods for fabricating such sensors |
-
2013
- 2013-12-05 CN CN201380063826.6A patent/CN105008878B/zh active Active
- 2013-12-05 WO PCT/IB2013/060686 patent/WO2014087380A1/en active Application Filing
- 2013-12-05 EP EP13860485.5A patent/EP2929308A4/en not_active Withdrawn
- 2013-12-05 US US14/649,660 patent/US10101274B2/en active Active
- 2013-12-05 BR BR112015013166A patent/BR112015013166A2/pt not_active Application Discontinuation
- 2013-12-05 JP JP2015546140A patent/JP6501714B2/ja active Active
- 2013-12-05 CA CA2862766A patent/CA2862766C/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA2862766C (en) | 2016-01-19 |
JP6501714B2 (ja) | 2019-04-17 |
EP2929308A1 (en) | 2015-10-14 |
CA2862766A1 (en) | 2014-06-12 |
US10101274B2 (en) | 2018-10-16 |
CN105008878A (zh) | 2015-10-28 |
JP2016502670A (ja) | 2016-01-28 |
US20150308958A1 (en) | 2015-10-29 |
EP2929308A4 (en) | 2015-12-16 |
CN105008878B (zh) | 2017-09-19 |
WO2014087380A1 (en) | 2014-06-12 |
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