|
GB1303061A
(enExample)
*
|
1969-05-03 |
1973-01-17 |
|
|
|
GB1293565A
(en)
|
1969-05-03 |
1972-10-18 |
Aspro Nicholas Ltd |
Aminophthalazines and pharmaceutical compositions thereof
|
|
GB2063249A
(en)
*
|
1979-10-09 |
1981-06-03 |
Mitsubishi Yuka Pharma |
4-Phenylphthalazine derivatives
|
|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
|
WO1989011279A1
(en)
|
1988-05-16 |
1989-11-30 |
Georgia State University Foundation, Inc. |
Nucleic acid interacting unfused heteropolycyclic compounds
|
|
ATE115136T1
(de)
|
1990-03-30 |
1994-12-15 |
Mitsubishi Chem Ind |
4-phenylphthalazin-derivate.
|
|
JPH03284669A
(ja)
*
|
1990-03-30 |
1991-12-16 |
Mitsubishi Kasei Corp |
4―フェニルフタラジン誘導体
|
|
TW279162B
(enExample)
*
|
1991-09-26 |
1996-06-21 |
Mitsubishi Chem Corp |
|
|
JP2668163B2
(ja)
|
1992-01-23 |
1997-10-27 |
ファイザー インク. |
コレステロール血症および抗アテローム動脈硬化症薬としての4−アリール−3−(ヘテロアリールウレイド)−1,2−ジヒドロ−2−オキソ−キノリン誘導体
|
|
US5565472A
(en)
|
1992-12-21 |
1996-10-15 |
Pfizer Inc. |
4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
|
|
DE4417746A1
(de)
|
1994-05-20 |
1995-11-23 |
Bayer Ag |
Neue Farbstoffe zum Massefärben von Kunststoffen
|
|
DE69533057T2
(de)
*
|
1994-08-09 |
2005-06-16 |
Eisai Co., Ltd. |
Kondensierte pyridazinverbindungen
|
|
US5763263A
(en)
|
1995-11-27 |
1998-06-09 |
Dehlinger; Peter J. |
Method and apparatus for producing position addressable combinatorial libraries
|
|
CA2258079A1
(en)
|
1996-08-20 |
1998-02-26 |
Mayu Shibazaki |
Remedy for erection failure comprising fused pyridazine compound
|
|
US20030124053A1
(en)
|
1996-10-07 |
2003-07-03 |
Barrett John Andrew |
Radiopharmaceuticals for imaging infection and inflammation
|
|
AU5614198A
(en)
|
1996-12-18 |
1998-07-15 |
Neurogen Corporation |
Isoquinolinamine and phthalazinamine derivatives which interact with crf receptors
|
|
US6486158B1
(en)
|
1998-08-14 |
2002-11-26 |
Cell Pathways, Inc. |
[4,5]-fused-3,6-disubstituted-pyridazines with sulfur-containing substituents in position three for the treatment of neoplasia
|
|
CN1161341C
(zh)
|
1999-03-22 |
2004-08-11 |
布里斯托尔-迈尔斯斯奎布公司 |
cGMP磷酸二酯酶的稠合吡啶并哒嗪抑制剂
|
|
JP2005510568A
(ja)
|
2001-11-30 |
2005-04-21 |
ファイザー・プロダクツ・インク |
アリール基が結合したアザポリサイクリック化合物
|
|
WO2004099158A1
(en)
|
2003-04-30 |
2004-11-18 |
Ricerca Biosciences, Llc. |
Monocyclic diazodioxide based bcl-2 protein antagonists
|
|
WO2005016000A1
(en)
|
2003-08-05 |
2005-02-24 |
Avalon Pharmaceuticals |
Derivatives of cyclic quinone and uses thereof
|
|
US7087621B2
(en)
|
2003-09-05 |
2006-08-08 |
Bristol-Myers Squibb Company |
Benzo- and azabenzodithiazole compounds
|
|
WO2005033288A2
(en)
|
2003-09-29 |
2005-04-14 |
The Johns Hopkins University |
Hedgehog pathway antagonists
|
|
JP5221952B2
(ja)
|
2004-05-08 |
2013-06-26 |
ノバルティス・インターナショナル・ファーマシューティカル・リミテッド |
3−アリール−5,6−ジ置換ピリダジン類
|
|
KR101179382B1
(ko)
|
2004-06-09 |
2012-09-03 |
에릭 엠. 카레이라 |
모노포스핀 화합물, 그의 전이 금속 착체 및 상기 착체를비대칭 촉매로서 사용하는 광학 활성 화합물의 제조 방법
|
|
US20060156485A1
(en)
|
2005-01-14 |
2006-07-20 |
The Procter & Gamble Company |
Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof
|
|
WO2006090273A2
(en)
|
2005-02-22 |
2006-08-31 |
Warner-Lambert Company Llc |
[1,8]naphthyridin-2-ones and related compounds with keto or hydroxyl linkers for the treatment of schizophrenia
|
|
WO2006110516A1
(en)
|
2005-04-11 |
2006-10-19 |
Abbott Laboratories |
Acylhydrazide p2x7 antagonists and uses thereof
|
|
CA2622677A1
(en)
|
2005-09-23 |
2007-04-05 |
Richard Schumacher |
Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
|
|
US8106066B2
(en)
|
2005-09-23 |
2012-01-31 |
Memory Pharmaceuticals Corporation |
Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
|
|
FR2891828B1
(fr)
|
2005-10-12 |
2007-12-21 |
Sanofi Aventis Sa |
Derives de la 1-amino-phtalazine substituee, leur preparation et leur application en therapeutique
|
|
AU2006311851A1
(en)
|
2005-11-03 |
2007-05-18 |
Ilypsa, Inc. |
Azaindole compounds and use thereof as phospholipase-A2 inhibitors
|
|
WO2007056281A2
(en)
|
2005-11-03 |
2007-05-18 |
Ilypsa, Inc. |
Multivalent indole compounds and use thereof as phospholipase-a2 inhibitors
|
|
WO2007056580A2
(en)
|
2005-11-08 |
2007-05-18 |
Pharmadyn, Inc. |
Methods and compositions for treating diseases associated with pathogenic proteins
|
|
JP2009120486A
(ja)
|
2005-12-05 |
2009-06-04 |
Mitsubishi Pharma Corp |
核内オーファン受容体の新規活性化剤及びその用途
|
|
AU2007208351C1
(en)
|
2006-01-23 |
2011-07-07 |
Amgen Inc. |
Aurora kinase modulators and method of use
|
|
US7560551B2
(en)
|
2006-01-23 |
2009-07-14 |
Amgen Inc. |
Aurora kinase modulators and method of use
|
|
US8658801B2
(en)
|
2006-02-16 |
2014-02-25 |
Syngenta Crop Protection, Llc |
Pesticides containing a bicyclic bisamide structure
|
|
CA2660114A1
(en)
|
2006-08-09 |
2008-02-14 |
Merck Frosst Canada Ltd. |
Azacycloalkane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
|
|
WO2008128968A1
(en)
|
2007-04-19 |
2008-10-30 |
Novartis Ag |
Nicotinic acid derivatives as modulators of metabotropic glutamate receptor-5
|
|
AU2008248165B2
(en)
|
2007-05-04 |
2011-12-08 |
Amgen Inc. |
Diazaquinolones that inhibit prolyl hydroxylase activity
|
|
US9023490B2
(en)
|
2007-06-15 |
2015-05-05 |
Versitech Limited |
Extended pi-conjugated platinum (II) complexes
|
|
WO2009035568A1
(en)
|
2007-09-07 |
2009-03-19 |
Amgen Inc. |
Annelated pyridazines for the treatment of tumors driven by inappropriate hedgehog signalling
|
|
WO2009038812A1
(en)
|
2007-09-20 |
2009-03-26 |
Amgen Inc. |
Condensed piperidine derivatives useful as vanilloid receptor ligands
|
|
WO2009079008A1
(en)
|
2007-12-19 |
2009-06-25 |
Yangbo Feng |
Benzopyrans and analogs as rho kinase inhibitors
|
|
AU2008345225A1
(en)
|
2007-12-21 |
2009-07-09 |
University Of Rochester |
Method for altering the lifespan of eukaryotic organisms
|
|
US8932557B2
(en)
|
2008-02-14 |
2015-01-13 |
Eli Lilly And Company |
Imaging agents for detecting neurological dysfunction
|
|
WO2009126947A2
(en)
|
2008-04-11 |
2009-10-15 |
The Regents Of The University Of Michigan |
Heteroaryl-substituted bicyclic smac mimetics and the uses thereof
|
|
AU2009246626A1
(en)
|
2008-05-15 |
2009-11-19 |
Merck Sharp & Dohme Corp. |
Oxazolobenzimidazole derivatives
|
|
WO2009152909A1
(en)
|
2008-06-16 |
2009-12-23 |
Merck Patent Gmbh |
Quinoxalinedione derivatives
|
|
WO2009157386A1
(ja)
|
2008-06-25 |
2009-12-30 |
住友化学株式会社 |
光学活性アミン化合物の製造方法
|
|
US20110218211A1
(en)
|
2008-08-16 |
2011-09-08 |
Genentech, Inc. |
Azaindole inhibitors of iap
|
|
WO2010036544A1
(en)
|
2008-09-26 |
2010-04-01 |
Merck Sharp & Dohme Corp. |
Oxazolobenzimidazole derivatives
|
|
MX2011009213A
(es)
|
2009-03-02 |
2011-12-14 |
Sirtris Pharmaceuticals Inc |
Quinolinas 8-sustituidas y analogos relacionados como moduladores de sirtuina.
|
|
TW201040191A
(en)
|
2009-03-27 |
2010-11-16 |
Abbott Gmbh & Co Kg |
Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors
|
|
CN102369199A
(zh)
|
2009-04-01 |
2012-03-07 |
巴斯夫欧洲公司 |
用于防治无脊椎动物害虫的异*唑啉化合物
|
|
EP2416772A1
(en)
|
2009-04-06 |
2012-02-15 |
PTC Therapeutics, Inc. |
Combinations of a hcv inhibitor such as bicyclic pyrrole derivatives and a therapeutic agent
|
|
WO2010117935A1
(en)
|
2009-04-06 |
2010-10-14 |
Schering Corporation |
Compounds and methods for antiviral treatment
|
|
WO2010151791A1
(en)
|
2009-06-25 |
2010-12-29 |
Amgen Inc. |
Heterocyclic compounds and their uses
|
|
US8981087B2
(en)
|
2009-07-29 |
2015-03-17 |
Karus Therapeutics Limited |
Benzo [E] [1,3] oxazin-4-one derivatives as phosphoinositide 3-kinase inhibitors
|
|
EP2464647B1
(en)
|
2009-08-11 |
2016-09-21 |
Bristol-Myers Squibb Company |
Azaindazoles as btk kinase modulators and use thereof
|
|
CN102791687B
(zh)
|
2009-12-18 |
2015-02-11 |
北京凯因科技股份有限公司 |
C型肝炎病毒复制的新型抑制剂
|
|
US8759535B2
(en)
|
2010-02-18 |
2014-06-24 |
High Point Pharmaceuticals, Llc |
Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof
|
|
UY33304A
(es)
|
2010-04-02 |
2011-10-31 |
Amgen Inc |
Compuestos heterocíclicos y sus usos
|
|
EP2571876B1
(en)
|
2010-05-21 |
2016-09-07 |
Merck Sharp & Dohme Corp. |
Substituted seven-membered heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes
|
|
CN102958930B
(zh)
|
2010-06-28 |
2018-04-27 |
默克专利有限公司 |
作为用于对抗癌症的激酶抑制剂的2,4-二芳基取代的[1,8]二氮杂萘化合物
|
|
MX2012015143A
(es)
|
2010-06-30 |
2013-07-03 |
Amgen Inc |
Compuestos heterociclicos que contienen nitrogeno como inhibidores de pi3k delta.
|
|
US20130165440A1
(en)
|
2010-09-14 |
2013-06-27 |
Exelixis, Inc. |
JAK1 Inhibitors
|
|
CN103119035B
(zh)
|
2010-09-27 |
2015-09-30 |
雅培股份有限两合公司 |
杂环化合物和它们作为糖原合成酶激酶-3抑制剂的用途
|
|
US20140107151A1
(en)
|
2011-05-17 |
2014-04-17 |
Principia Biophama Inc. |
Tyrosine kinase inhibitors
|
|
CN103534237B
(zh)
|
2011-05-18 |
2016-06-15 |
先正达参股股份有限公司 |
基于芳硫基乙酰胺衍生物的杀虫化合物
|
|
JP5978302B2
(ja)
|
2011-08-08 |
2016-08-24 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung |
リゾホスファチジン酸アンタゴニストとしての(n−ベンズイミダゾール−2−イル)−シクロプロパンカルボキサミド
|
|
JP2014524459A
(ja)
|
2011-08-25 |
2014-09-22 |
シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト |
シロアリおよびアリの防除方法
|
|
WO2013078254A1
(en)
|
2011-11-22 |
2013-05-30 |
Array Biopharma Inc. |
Bicyclic heteroaryl derivatives as kinase inhibitors
|
|
UA112897C2
(uk)
|
2012-05-09 |
2016-11-10 |
Байєр Фарма Акцієнгезелльшафт |
Біциклічно заміщені урацили та їх застосування для лікування і/або профілактики захворювань
|
|
WO2013176698A1
(en)
|
2012-05-22 |
2013-11-28 |
Eli Lilly And Company |
Carboline and carbazole based imaging agents for detecting neurological dysfunction
|
|
TWI610916B
(zh)
|
2012-08-03 |
2018-01-11 |
廣東東陽光藥業有限公司 |
作爲丙型肝炎抑制劑的橋環化合物及其在藥物中的應用
|
|
US9675073B2
(en)
|
2012-11-21 |
2017-06-13 |
Syngenta Participations Ag |
Insecticidal compounds based on N-arylsulfanylmethylcarboxamidearylthiosulfonamides derivatives
|
|
WO2014080291A2
(en)
|
2012-11-21 |
2014-05-30 |
Rvx Therapeutics Inc. |
Biaryl derivatives as bromodomain inhibitors
|
|
WO2014079935A1
(en)
|
2012-11-21 |
2014-05-30 |
Syngenta Participations Ag |
Insecticidal compounds based on arylthioacetamide derivatives
|
|
WO2014086737A1
(de)
|
2012-12-06 |
2014-06-12 |
Bayer Cropscience Ag |
Kondensierte 2-pyridon-3-carboxamide und ihre verwendung als herbizide
|
|
TW201439060A
(zh)
|
2013-02-27 |
2014-10-16 |
Sunshine Lake Pharma Co Ltd |
作爲丙型肝炎抑制劑的橋環化合物及其藥物組合物和用途
|
|
GB201311953D0
(en)
|
2013-07-03 |
2013-08-14 |
Redx Pharma Ltd |
Compounds
|
|
AR097631A1
(es)
|
2013-09-16 |
2016-04-06 |
Bayer Pharma AG |
Trifluorometilpirimidinonas sustituidas con heterociclos y sus usos
|
|
UY35809A
(es)
|
2013-11-05 |
2015-05-29 |
Bayer Pharma AG |
(aza)piridopirazolopirimidinonas e indazolopirimidinonas y sus usos
|
|
CN106458912B
(zh)
|
2014-04-04 |
2020-10-27 |
辉瑞公司 |
双环稠合的杂芳基或芳基化合物以及它们作为irak4拟制剂的用途
|
|
CN103992311B
(zh)
|
2014-06-20 |
2017-01-25 |
东南大学 |
Hedgehog信号通路抑制剂
|
|
US9617279B1
(en)
|
2014-06-24 |
2017-04-11 |
Bristol-Myers Squibb Company |
Imidazooxadiazole compounds
|
|
US9763922B2
(en)
|
2014-11-27 |
2017-09-19 |
Genentech, Inc. |
Therapeutic compounds and uses thereof
|
|
RU2741387C2
(ru)
|
2014-12-22 |
2021-01-25 |
Акарна Терапьютикс, Лтд. |
Конденсированные бициклические соединения для лечения заболевания
|
|
US20180093956A1
(en)
|
2015-02-06 |
2018-04-05 |
Abbvie Inc. |
Substituted phthalazines
|
|
KR102727059B1
(ko)
|
2015-02-16 |
2024-11-05 |
더 유니버서티 어브 퀸슬랜드 |
설포닐우레아와 관련 화합물 및 그 용도
|
|
CN113750101A
(zh)
|
2015-12-10 |
2021-12-07 |
Ptc医疗公司 |
用于治疗亨廷顿病的方法
|
|
FR3046933B1
(fr)
|
2016-01-25 |
2018-03-02 |
Galderma Research & Development |
Inhibiteurs nlrp3 pour le traitement des pathologies cutanees inflammatoires
|
|
BR112018067442A8
(pt)
|
2016-02-12 |
2024-01-09 |
Pharmaxis Ltd |
Composto, composição farmacêutica, método de inibir a atividade da amina oxidase, método de tratar uma condição e uso de um composto
|
|
WO2017140778A1
(en)
|
2016-02-16 |
2017-08-24 |
The University Of Queensland |
Sulfonylureas and related compounds and use of same
|
|
WO2017144341A1
(de)
|
2016-02-23 |
2017-08-31 |
Bayer Cropscience Aktiengesellschaft |
Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
|
|
EP3236267B1
(en)
|
2016-04-18 |
2021-09-08 |
Roche Diagnostics GmbH |
Decapper and apparatus
|
|
AU2017254523B2
(en)
|
2016-04-18 |
2021-09-02 |
Novartis Ag |
Compounds and compositions for treating conditions associated with NLRP activity
|
|
AU2017253937B2
(en)
|
2016-04-18 |
2021-08-05 |
Novartis Ag |
Compounds and compositions for treating conditions associated with NLRP activity
|
|
EP3272739A1
(en)
|
2016-07-20 |
2018-01-24 |
NodThera Limited |
Sulfonyl urea derivatives and their use in the control of interleukin-1 activity
|
|
WO2018031680A1
(en)
|
2016-08-10 |
2018-02-15 |
Fronthera U.S. Pharmaceuticals Llc |
Novel compounds, uses and methods for their preparation
|
|
KR102507847B1
(ko)
*
|
2016-10-28 |
2023-03-08 |
서울대학교병원 |
페닐 프탈라진 유도체, 이의 제조 방법 및 이를 포함하는 약학적 조성물
|
|
WO2018138050A1
(de)
|
2017-01-26 |
2018-08-02 |
Bayer Aktiengesellschaft |
Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
|
|
IL312367A
(en)
|
2017-01-31 |
2024-06-01 |
Arvinas Operations Inc |
Cereblon ligands and bifunctional compounds comprising the same
|
|
WO2018172925A1
(en)
|
2017-03-23 |
2018-09-27 |
Vitas Pharma Research Pvt Ltd |
Inhibitors of dna gyrase for treatment of bacterial infections
|
|
KR101943428B1
(ko)
|
2017-03-24 |
2019-01-30 |
엘티소재주식회사 |
유기 발광 소자 및 유기 발광 소자의 유기물층용 조성물
|
|
WO2018174678A1
(ko)
|
2017-03-24 |
2018-09-27 |
희성소재(주) |
헤테로고리 화합물 및 이를 포함하는 유기 발광 소자
|
|
JOP20190272A1
(ar)
|
2017-05-22 |
2019-11-21 |
Amgen Inc |
مثبطات kras g12c وطرق لاستخدامها
|
|
JP2020521741A
(ja)
|
2017-05-25 |
2020-07-27 |
アラクセス ファーマ エルエルシー |
がんの処置のための化合物およびその使用の方法
|
|
WO2018221433A1
(ja)
|
2017-05-29 |
2018-12-06 |
第一三共株式会社 |
ヘテロアリールアミン誘導体
|
|
TWI684637B
(zh)
|
2017-07-20 |
2020-02-11 |
南韓商Lg化學股份有限公司 |
化合物及包括此化合物的有機發光裝置
|
|
TW201910316A
(zh)
|
2017-08-15 |
2019-03-16 |
愛爾蘭商英弗雷佐姆有限公司 |
新穎化合物
|
|
CA3073333A1
(en)
|
2017-08-21 |
2019-02-28 |
Merck Patent Gmbh |
Bezimidazole derivatives as adenosine receptor antagonists
|
|
CN110526898A
(zh)
|
2018-05-25 |
2019-12-03 |
北京诺诚健华医药科技有限公司 |
3-吲唑啉酮类化合物、其制备方法及其在医药学上的应用
|
|
CN110563722A
(zh)
|
2018-06-06 |
2019-12-13 |
上海青煜医药科技有限公司 |
吡啶或哒嗪并环化合物及其应用
|
|
WO2020021015A1
(en)
|
2018-07-26 |
2020-01-30 |
Esteve Pharmaceuticals, S.A. |
New imidazopyridine derivatives for treating pain and pain related conditions
|
|
US12453279B2
(en)
|
2018-08-22 |
2025-10-21 |
Universal Display Corporation |
Organic electroluminescent materials and devices
|
|
CN119320388A
(zh)
|
2019-02-04 |
2025-01-17 |
斯基霍克疗法公司 |
用于调节剪接的方法和组合物
|
|
KR102721075B1
(ko)
|
2019-02-15 |
2024-10-24 |
삼성전자주식회사 |
축합환 화합물 및 이를 포함한 유기 발광 소자
|
|
UY38687A
(es)
*
|
2019-05-17 |
2023-05-15 |
Novartis Ag |
Inhibidores del inflamasoma nlrp3, composiciones, combinaciones de los mismos y métodos para su uso
|
|
US11618751B1
(en)
|
2022-03-25 |
2023-04-04 |
Ventus Therapeutics U.S., Inc. |
Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives
|
|
JP7738910B2
(ja)
*
|
2020-03-27 |
2025-09-16 |
テンヴィー・セラピューティクス,インコーポレーテッド |
置換ピリダジン化合物
|
|
JP2023527010A
(ja)
|
2020-05-28 |
2023-06-26 |
ヤンセン ファーマシューティカ エヌ.ベー. |
化合物
|
|
MX2022015812A
(es)
|
2020-06-09 |
2023-04-05 |
Pardes Biosciences Inc |
Inhibidores de cisteina proteasas y sus metodos de uso.
|
|
WO2022135567A1
(zh)
|
2020-12-25 |
2022-06-30 |
上海拓界生物医药科技有限公司 |
一类含哒嗪的化合物及其医药用途
|
|
WO2022166890A1
(zh)
|
2021-02-08 |
2022-08-11 |
南京明德新药研发有限公司 |
取代的哒嗪苯酚类衍生物
|
|
IL307157A
(en)
|
2021-04-07 |
2023-11-01 |
Forma Therapeutics Inc |
Ubiquitin-specific protease 1 (USP1) inhibition
|
|
US11319319B1
(en)
|
2021-04-07 |
2022-05-03 |
Ventus Therapeutics U.S., Inc. |
Compounds for inhibiting NLRP3 and uses thereof
|
|
WO2022230912A1
(ja)
|
2021-04-28 |
2022-11-03 |
アステラス製薬株式会社 |
置換トリアジン化合物
|
|
BR112023022471A2
(pt)
|
2021-04-29 |
2024-01-16 |
Janssen Pharmaceutica Nv |
Derivados de ftalazinona como inibidores de inflamassoma nlrp3
|
|
FI4337652T3
(fi)
|
2021-05-12 |
2025-06-20 |
Hoffmann La Roche |
NLRP3:n estäjiä
|
|
AR126053A1
(es)
|
2021-06-04 |
2023-09-06 |
Hoffmann La Roche |
Derivados de triazina
|
|
US20240294542A1
(en)
|
2021-06-05 |
2024-09-05 |
Transthera Sciences (Nanjing), Inc. |
Nlrp3 inflammasome inhibitor and application thereof
|
|
JP2024529839A
(ja)
|
2021-06-29 |
2024-08-14 |
ズーマゲン バイオサイエンシーズ エルティーディー |
Nlrp3モジュレーター
|
|
DK4363406T3
(da)
|
2021-07-02 |
2025-12-01 |
Astrazeneca Ab |
Nlrp3-inflammasomhæmmere
|
|
AU2022306289A1
(en)
|
2021-07-09 |
2024-01-18 |
Aligos Therapeutics, Inc. |
Anti-viral compounds
|
|
IL310264A
(en)
|
2021-07-21 |
2024-03-01 |
Nico Therapeutics Inc |
Annulated pyridazine compound
|
|
WO2023028536A1
(en)
|
2021-08-25 |
2023-03-02 |
Ptc Therapeutics, Inc. |
1,2,4-triazine derivatives useful as inhibitors of nlrp3
|
|
KR20240052009A
(ko)
|
2021-08-25 |
2024-04-22 |
자이두스 라이프사이언시즈 리미티드 |
신경염증성 장애의 치료
|
|
WO2023028534A1
(en)
|
2021-08-25 |
2023-03-02 |
Ptc Therapeutics, Inc. |
Inhibitors of nlrp3
|
|
CA3233482A1
(en)
|
2021-09-30 |
2023-04-06 |
Origiant Pharmaceutical Co., Ltd |
Pharmaceutical use and preparation method for substituted heteroaryl phthalazine derivative
|
|
AR127386A1
(es)
|
2021-10-19 |
2024-01-17 |
Hoffmann La Roche |
Compuestos heteroarilicos bicíclicos fusionados útiles como inhibidores de nlrp3
|
|
CN116102535A
(zh)
|
2021-10-22 |
2023-05-12 |
索智生物科技(浙江)有限公司 |
一种含氮化合物、其制备方法及应用
|
|
JP2024540445A
(ja)
|
2021-11-17 |
2024-10-31 |
エフ. ホフマン-ラ ロシュ アーゲー |
複素環式nlrp3阻害剤
|
|
WO2023088987A1
(en)
|
2021-11-19 |
2023-05-25 |
F. Hoffmann-La Roche Ag |
Pyridazine derivatives as inhibitors of nlrp3
|
|
US20250074888A1
(en)
|
2021-12-29 |
2025-03-06 |
Neumora Therapeutics, Inc. |
Pyridazine derivatives as modulators of nlrp3 inflammasome and related methods
|
|
WO2023131277A1
(zh)
|
2022-01-07 |
2023-07-13 |
药捷安康(南京)科技股份有限公司 |
Nlrp3炎症小体抑制剂及其应用
|
|
CN116726020A
(zh)
|
2022-03-08 |
2023-09-12 |
上海拓界生物医药科技有限公司 |
一类含哒嗪的化合物的药物组合物及其医药用途
|
|
AU2023234527A1
(en)
|
2022-03-15 |
2024-10-31 |
Zomagen Biosciences Ltd |
Nlrp3 modulators
|
|
AU2023238121A1
(en)
|
2022-03-25 |
2024-10-10 |
Ventus Therapeutics U.S., Inc. |
Pyrido-[3,4-d]pyridazine amine derivatives useful as nlrp3 derivatives
|
|
AU2023245348A1
(en)
|
2022-03-31 |
2024-09-12 |
Hangzhou Highlightll Pharmaceutical Co., Ltd |
Nlrp3 inflammasome inhibitors
|
|
AR129012A1
(es)
|
2022-04-07 |
2024-07-03 |
Takeda Pharmaceuticals Co |
Derivados de piridazina fusionados
|
|
CN116969920A
(zh)
|
2022-04-29 |
2023-10-31 |
上海辉启生物医药科技有限公司 |
稠合哒嗪衍生物及其制备方法与医药用途
|
|
IL316607A
(en)
|
2022-05-13 |
2024-12-01 |
Neumora Therapeutics Inc |
NLRP3 inflammasome modulators and related products and methods
|
|
WO2023232917A1
(en)
|
2022-06-03 |
2023-12-07 |
F. Hoffmann-La Roche Ag |
Novel compounds
|
|
WO2024006559A1
(en)
|
2022-07-01 |
2024-01-04 |
Neumora Therapeutics, Inc. |
Modulators of nlrp3 inflammasome and related products and methods
|
|
WO2024012551A1
(zh)
|
2022-07-14 |
2024-01-18 |
南京明德新药研发有限公司 |
氘取代的哒嗪苯并噻吩化合物及其应用
|
|
KR20250036233A
(ko)
|
2022-07-14 |
2025-03-13 |
에이씨 이뮨 에스에이 |
Nlrp3 인플라마좀 경로의 조절제로서의 피롤로트리아진 및 이미다조트리아진 유도체
|
|
EP4558499A1
(en)
|
2022-07-21 |
2025-05-28 |
F. Hoffmann-La Roche AG |
Nlrp3 inhibitors
|
|
JP2025526423A
(ja)
|
2022-07-28 |
2025-08-13 |
エーシー・イミューン・エス・アー |
新規化合物
|
|
UY40374A
(es)
|
2022-08-03 |
2024-02-15 |
Novartis Ag |
Inhibidores de inflamasoma nlrp3
|
|
JP2025526692A
(ja)
|
2022-08-10 |
2025-08-15 |
武田薬品工業株式会社 |
複素環式化合物
|
|
CN116789674B
(zh)
|
2022-08-24 |
2024-05-24 |
杭州高光制药有限公司 |
Nlrp3炎性小体抑制剂
|
|
US20240124451A1
(en)
|
2022-09-23 |
2024-04-18 |
Merck Sharp & Dohme Llc |
Phthalazine derivatives useful as inhibitors of nod-like receptor protein 3
|
|
WO2024090469A1
(ja)
|
2022-10-26 |
2024-05-02 |
アステラス製薬株式会社 |
縮環ピリダジン誘導体
|
|
US12331048B2
(en)
|
2022-10-31 |
2025-06-17 |
Ventus Therapeutics U.S., Inc. |
Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors
|
|
WO2024097629A1
(en)
|
2022-10-31 |
2024-05-10 |
Ventus Therapeutics U.S., Inc. |
Bridged bicyclic heterocycloalkyl pyrido-[3,4-d]pyridazine amine derivatives useful as nlrp3 inhibitors
|
|
WO2024097598A1
(en)
|
2022-11-02 |
2024-05-10 |
Merck Sharp & Dohme Llc |
Triazines useful as inhibitors of nod-like receptor protein 3
|
|
TW202419090A
(zh)
|
2022-11-04 |
2024-05-16 |
大陸商藥捷安康(南京)科技股份有限公司 |
Nlrp3炎症小體抑制劑及其應用
|
|
WO2024094150A1
(en)
|
2022-11-04 |
2024-05-10 |
Insilico Medicine Ip Limited |
Nlrp3 inflammasome inhibitors and uses thereof
|
|
WO2024099992A1
(en)
|
2022-11-09 |
2024-05-16 |
F. Hoffmann-La Roche Ag |
Triazinone derivatives as nlrp3 inhibitors
|
|
PE20251675A1
(es)
|
2022-11-09 |
2025-06-30 |
Hoffmann La Roche |
Derivados de triazinona como inhibidores de nlrp3
|
|
CN120152964A
(zh)
|
2022-11-09 |
2025-06-13 |
豪夫迈·罗氏有限公司 |
作为nlrp3抑制剂的三嗪酮衍生物
|
|
CN118056822A
(zh)
|
2022-11-18 |
2024-05-21 |
正大天晴药业集团股份有限公司 |
一种哒嗪并环化合物及其用途
|
|
CN120225506A
(zh)
|
2022-11-25 |
2025-06-27 |
成都赜灵生物医药科技有限公司 |
桥环并哒嗪类化合物及其用途
|
|
PE20251845A1
(es)
|
2022-12-07 |
2025-07-17 |
Hoffmann La Roche |
Compuestos novedosos como moduladores de la inhibicion de nlrp3
|
|
AR131282A1
(es)
|
2022-12-08 |
2025-03-05 |
Hoffmann La Roche |
Compuestos novedosos
|
|
EP4637746A1
(en)
|
2022-12-19 |
2025-10-29 |
Merck Sharp & Dohme LLC |
6,6 bicyclic heterocyles useful as inhibitors of nod-like receptor protein 3
|
|
EP4638434A1
(en)
|
2022-12-23 |
2025-10-29 |
Neumora Therapeutics, Inc. |
Modulators of nlrp3 inflammasome and related products and methods
|
|
CN120379995A
(zh)
|
2022-12-27 |
2025-07-25 |
正大天晴药业集团股份有限公司 |
一种哒嗪稠芳环化合物及其用途
|
|
EP4644380A1
(en)
|
2022-12-28 |
2025-11-05 |
Changchun Genescience Pharmaceutical Co., Ltd. |
Pyridazine nlrp3 inhibitor compound, pharmaceutical composition, and preparation method therefor and use thereof
|
|
CN120584106A
(zh)
|
2022-12-28 |
2025-09-02 |
阿斯利康(瑞典)有限公司 |
Nlrp3炎性小体抑制剂
|
|
AU2023414924A1
(en)
|
2022-12-30 |
2025-07-03 |
Ptc Therapeutics, Inc. |
Heterocyclic and heteroaryl compounds as inhibitors of nlrp3
|
|
AU2024206808A1
(en)
|
2023-01-03 |
2025-07-17 |
Kodiak Sciences Inc. |
Organic compounds as nlrp3 inhibitors
|
|
CN120981462A
(zh)
|
2023-01-31 |
2025-11-18 |
詹森药业有限公司 |
咪唑并[1,2-d][1,2,4]三嗪作为NLRP3抑制剂
|
|
CN121001996A
(zh)
|
2023-01-31 |
2025-11-21 |
詹森药业有限公司 |
作为nlrp3抑制剂的吡啶-2(1h)-酮和嘧啶-4(3h)-酮
|
|
CN120957980A
(zh)
|
2023-01-31 |
2025-11-14 |
詹森药业有限公司 |
作为nlrp3抑制剂的2-(哒嗪-3-基)-5-(三氟甲基)苯酚
|
|
EP4658654A1
(en)
|
2023-01-31 |
2025-12-10 |
Janssen Pharmaceutica NV |
Pyrrolo[1,2-d][1,2,4]triazines and pyrazolo[1,5-d] [1,2,4]triazines as nlrp3 inhibitors
|
|
EP4658649A1
(en)
|
2023-01-31 |
2025-12-10 |
Janssen Pharmaceutica NV |
[1,2,4]triazolo[4,3-a]pyridines and [1,2,4]triazolo[4,3-a]pyrazines as nlrp3 inhibitors
|