JP2020502047A5 - - Google Patents
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- Publication number
- JP2020502047A5 JP2020502047A5 JP2019523589A JP2019523589A JP2020502047A5 JP 2020502047 A5 JP2020502047 A5 JP 2020502047A5 JP 2019523589 A JP2019523589 A JP 2019523589A JP 2019523589 A JP2019523589 A JP 2019523589A JP 2020502047 A5 JP2020502047 A5 JP 2020502047A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- solvate
- compound according
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662423095P | 2016-11-16 | 2016-11-16 | |
| US62/423,095 | 2016-11-16 | ||
| PCT/US2017/061867 WO2018093946A1 (en) | 2016-11-16 | 2017-11-15 | Magl inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020502047A JP2020502047A (ja) | 2020-01-23 |
| JP2020502047A5 true JP2020502047A5 (enExample) | 2020-12-17 |
| JP6987859B2 JP6987859B2 (ja) | 2022-01-05 |
Family
ID=62107273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019523589A Expired - Fee Related JP6987859B2 (ja) | 2016-11-16 | 2017-11-15 | Ｍａｇｌ阻害剤 |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US9981930B1 (enExample) |
| EP (1) | EP3541822B1 (enExample) |
| JP (1) | JP6987859B2 (enExample) |
| KR (1) | KR20190077087A (enExample) |
| CN (1) | CN110248947B (enExample) |
| AR (1) | AR110088A1 (enExample) |
| AU (1) | AU2017361250A1 (enExample) |
| BR (1) | BR112019009991A2 (enExample) |
| CA (1) | CA3043612A1 (enExample) |
| CL (1) | CL2019001335A1 (enExample) |
| CO (1) | CO2019005038A2 (enExample) |
| CR (1) | CR20190243A (enExample) |
| DO (1) | DOP2019000121A (enExample) |
| EA (1) | EA201991074A1 (enExample) |
| EC (1) | ECSP19035377A (enExample) |
| ES (1) | ES2908632T3 (enExample) |
| IL (1) | IL266550A (enExample) |
| JO (1) | JOP20190105A1 (enExample) |
| MA (1) | MA46860A (enExample) |
| MX (1) | MX2019005771A (enExample) |
| NI (1) | NI201900050A (enExample) |
| PE (1) | PE20191146A1 (enExample) |
| PH (1) | PH12019501102A1 (enExample) |
| RU (1) | RU2019116514A (enExample) |
| TN (1) | TN2019000150A1 (enExample) |
| TW (1) | TW201831458A (enExample) |
| WO (1) | WO2018093946A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2793148T3 (es) | 2012-01-06 | 2020-11-13 | Lundbeck La Jolla Research Center Inc | Compuestos de carbamato y métodos para fabricarlos y usarlos |
| CA2984480A1 (en) | 2015-05-11 | 2016-11-17 | Abide Therapeutics, Inc. | Methods of treating inflammation or neuropathic pain |
| US10899737B2 (en) | 2016-09-19 | 2021-01-26 | Lundbeck La Jolla Research Center, Inc. | Piperazine carbamates and methods of making and using same |
| AU2017361254B2 (en) | 2016-11-16 | 2021-09-23 | H. Lundbeck A/S. | Pharmaceutical formulations |
| EP3541807B1 (en) | 2016-11-16 | 2021-09-29 | H. Lundbeck A/S | A crystalline form of a magl inhibitor |
| JOP20190106A1 (ar) * | 2016-11-16 | 2019-05-09 | Lundbeck La Jolla Research Center Inc | مثبطات أحادي أسيل جليسرول ليباز (magl) |
| JOP20190107A1 (ar) | 2016-11-16 | 2019-05-09 | Lundbeck La Jolla Research Center Inc | مثبطات أحادي أسيل جليسرول ليباز (magl) |
| CA3072923A1 (en) | 2017-08-29 | 2019-03-07 | Lundbeck La Jolla Research Center, Inc. | Spirocycle compounds and methods of making and using same |
| GEP20227373B (en) * | 2017-11-02 | 2022-04-25 | Aicuris Gmbh & Co Kg | Novel, highly active amino-thiazole substituted indole-2-carboxamides active against the hepatitis b virus (hbv) |
| CR20200545A (es) | 2018-05-15 | 2020-12-17 | Lundbeck La Jolla Research Center Inc | Inhibidores magl |
| CN115427403A (zh) * | 2020-04-21 | 2022-12-02 | H.隆德贝克有限公司 | 单酰基甘油脂肪酶抑制剂的合成 |
| TWI904281B (zh) | 2020-11-13 | 2025-11-11 | 丹麥商Ｈ 朗德貝克公司 | Magl抑制劑 |
| CA3242372A1 (en) | 2021-12-29 | 2023-07-06 | Psy Therapeutics, Inc. | Inhibiting monoacylglycerol lipase (magl) |
| AU2023264787A1 (en) | 2022-05-04 | 2024-10-31 | H. Lundbeck A/S | Crystalline form of 1,1,1,3,3,3-hexafluoropropan-2-yl (s)-1-(pyridazin-3-ylcarbamoyl)-6 azaspiro[2.5]octane-6-carboxylate as monoacylglycerol lipase inhibitor. |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1593586A (enExample) | 1967-10-17 | 1970-06-01 | ||
| JPS6183073A (ja) | 1984-10-01 | 1986-04-26 | Oki Electric Ind Co Ltd | 印字装置の用紙送り方法 |
| WO1989011794A1 (fr) | 1988-06-07 | 1989-12-14 | Rikagaku Kenkyusho | Inhibiteur de la croissance de plantes |
| DE69211015T2 (de) | 1991-11-27 | 1997-01-09 | Du Pont | Herbizide acylierte amino-(phenyl-oder-pyridinyl-oder thienyl-)phenyl derivate |
| DE69408873T2 (de) | 1993-12-22 | 1998-07-09 | Shell Int Research | Verfahren zur herstellung von carbamaten |
| EP0863879A1 (en) | 1995-11-15 | 1998-09-16 | Zeneca Limited | Herbicidal substituted pyrazole compounds |
| AU3440597A (en) | 1996-07-02 | 1998-01-21 | Novartis Ag | N-phenylimino heterocyclic derivatives and their use as herbicides |
| RU2167150C2 (ru) | 1998-03-25 | 2001-05-20 | Фокин Александр Васильевич | Полифторалкил-n-арилкарбаматы, обладающие антимикробной активностью |
| ATE432993T1 (de) | 1999-10-04 | 2009-06-15 | Univ New Jersey Med | Tar rna bindende peptide |
| EP1201298A1 (en) | 2000-10-24 | 2002-05-02 | Urea Casale S.A. | Carbamate condensation unit |
| DE10348022A1 (de) | 2003-10-15 | 2005-05-25 | Imtm Gmbh | Neue Dipeptidylpeptidase IV-Inhibitoren zur funktionellen Beeinflussung unterschiedlicher Zellen und zur Behandlung immunologischer, entzündlicher, neuronaler und anderer Erkrankungen |
| FR2864080B1 (fr) | 2003-12-23 | 2006-02-03 | Sanofi Synthelabo | Derives de 1-piperazine-et-1-homopiperazine-carboxylates, leur preparation et leur application en therapeutique |
| WO2005063698A1 (en) | 2003-12-31 | 2005-07-14 | Council Of Scientific & Industrial Research | Process for preparing carbamates |
| KR20070026382A (ko) | 2004-02-18 | 2007-03-08 | 아스트라제네카 아베 | 아세틸린성 피페라진 화합물 및 대사성 글루타메이트수용체 길항제로서 이들의 용도 |
| AR048528A1 (es) * | 2004-04-07 | 2006-05-03 | Millennium Pharm Inc | Compuestos derivados de quinolina como antagonistas del receptor de pgd2 para el tratamiento de enfermedades inflamatorias y composiciones farmacéuticas que los contienen. |
| CA2589877A1 (en) | 2004-12-23 | 2006-06-29 | F. Hoffmann-La Roche Ag | Carbamate substituted imidazo- and pyrrolo-pyridines as protein kinase inhibitors |
| RS56194B1 (sr) | 2004-12-30 | 2017-11-30 | Janssen Pharmaceutica Nv | Derivativi fenilamida 4-(benzil)-piperazin-1-karboksilne kiseline i slična jedinjenja kao modulatori hidrolaze amida masnih kiselina (faah) za lečenje anksioznosti, bola i ostalih stanja |
| JP2009523729A (ja) | 2006-01-13 | 2009-06-25 | ピーティーシー セラピューティクス，インコーポレーテッド | Ｃ型肝炎の治療方法 |
| US20100234351A1 (en) | 2006-02-23 | 2010-09-16 | Takeda Pharmaceutical Company Limited | Fused nitrogen-comprising heterocyclic compound |
| MX2009006706A (es) | 2006-12-22 | 2009-07-02 | Astex Therapeutics Ltd | Compuestos heterociclicos biciclicos como inhibidores del receptor del factor de crecimiento de fibroblastos. |
| CN101711154A (zh) | 2007-02-26 | 2010-05-19 | 科森生物科学公司 | 氨基甲酸酯化合物 |
| JP2008239616A (ja) * | 2007-02-28 | 2008-10-09 | Iyaku Bunshi Sekkei Kenkyusho:Kk | Ｈｄｌ上昇剤 |
| US8188098B2 (en) | 2008-05-19 | 2012-05-29 | Hoffmann-La Roche Inc. | GPR119 receptor agonists |
| EP2328897A1 (en) | 2008-07-16 | 2011-06-08 | Schering Corporation | Bicyclic heterocycle derivatives and their use as gpcr modulators |
| EP2373315A4 (en) | 2008-11-14 | 2012-06-27 | Scripps Research Inst | METHOD AND COMPOSITIONS RELATED TO TARGETING OF MONOACYLGLYCEROLLIPASE |
| CA2755806A1 (en) | 2009-03-23 | 2010-09-30 | Msd K.K. | Novel aminopyridine derivatives having aurora a selective inhibitory action |
| UA107791C2 (en) | 2009-05-05 | 2015-02-25 | Dow Agrosciences Llc | Pesticidal compositions |
| ES2433235T3 (es) | 2009-11-03 | 2013-12-10 | Bayer Intellectual Property Gmbh | Fluorouretanos como aditivos en una formulación de fotopolímero |
| FR2960875B1 (fr) | 2010-06-04 | 2012-12-28 | Sanofi Aventis | Derives de carbamates d'hexafluoroisopropyle, leur preparation et leur application en therapeutique |
| ES2793148T3 (es) | 2012-01-06 | 2020-11-13 | Lundbeck La Jolla Research Center Inc | Compuestos de carbamato y métodos para fabricarlos y usarlos |
| KR101893112B1 (ko) | 2012-01-06 | 2018-08-30 | 아지오스 파마슈티컬스 아이엔씨. | 치료학적으로 활성인 화합물 및 이의 이용 방법 |
| WO2013142307A1 (en) * | 2012-03-19 | 2013-09-26 | Abide Therapeutics | Carbamate compounds and of making and using same |
| US9551036B2 (en) | 2013-02-25 | 2017-01-24 | Whitehead Institute For Biomedical Research | Metabolic gene mesenchymal signatures and uses thereof |
| JP6647592B2 (ja) | 2013-07-03 | 2020-02-14 | ルンドベック ラ ホーヤ リサーチ センター，インク． | ピロロピロールカルバメート、および関連する有機化合物、医薬組成物、ならびにその医学的使用 |
| CA2979537C (en) | 2015-03-18 | 2023-08-29 | Abide Therapeutics, Inc. | Piperazine carbamates and methods of making and using same |
| CA2984480A1 (en) * | 2015-05-11 | 2016-11-17 | Abide Therapeutics, Inc. | Methods of treating inflammation or neuropathic pain |
| US10463753B2 (en) * | 2016-02-19 | 2019-11-05 | Lundbeck La Jolla Research Center, Inc. | Radiolabeled monoacylglycerol lipase occupancy probe |
| ES2861648T3 (es) * | 2016-05-12 | 2021-10-06 | Lundbeck La Jolla Research Center Inc | Compuestos de espirociclo y procedimientos de fabricación y uso de los mismos |
| JOP20190107A1 (ar) * | 2016-11-16 | 2019-05-09 | Lundbeck La Jolla Research Center Inc | مثبطات أحادي أسيل جليسرول ليباز (magl) |
| JOP20190267A1 (ar) * | 2017-05-23 | 2019-11-18 | Lundbeck La Jolla Research Center Inc | مثبطات بيرازول magl |
-
2017
- 2017-06-16 JO JOP/2019/0105A patent/JOP20190105A1/ar unknown
- 2017-11-15 PE PE2019001015A patent/PE20191146A1/es unknown
- 2017-11-15 BR BR112019009991A patent/BR112019009991A2/pt not_active Application Discontinuation
- 2017-11-15 AU AU2017361250A patent/AU2017361250A1/en not_active Abandoned
- 2017-11-15 JP JP2019523589A patent/JP6987859B2/ja not_active Expired - Fee Related
- 2017-11-15 MA MA046860A patent/MA46860A/fr unknown
- 2017-11-15 CN CN201780083635.4A patent/CN110248947B/zh not_active Expired - Fee Related
- 2017-11-15 AR ARP170103183A patent/AR110088A1/es unknown
- 2017-11-15 TN TNP/2019/000150A patent/TN2019000150A1/en unknown
- 2017-11-15 KR KR1020197016859A patent/KR20190077087A/ko not_active Withdrawn
- 2017-11-15 EA EA201991074A patent/EA201991074A1/ru unknown
- 2017-11-15 US US15/814,318 patent/US9981930B1/en active Active
- 2017-11-15 CR CR20190243A patent/CR20190243A/es unknown
- 2017-11-15 CA CA3043612A patent/CA3043612A1/en not_active Abandoned
- 2017-11-15 ES ES17871883T patent/ES2908632T3/es active Active
- 2017-11-15 MX MX2019005771A patent/MX2019005771A/es unknown
- 2017-11-15 EP EP17871883.9A patent/EP3541822B1/en active Active
- 2017-11-15 RU RU2019116514A patent/RU2019116514A/ru not_active Application Discontinuation
- 2017-11-15 WO PCT/US2017/061867 patent/WO2018093946A1/en not_active Ceased
- 2017-11-16 TW TW106139750A patent/TW201831458A/zh unknown
-
2019
- 2019-05-12 IL IL266550A patent/IL266550A/en unknown
- 2019-05-16 CL CL2019001335A patent/CL2019001335A1/es unknown
- 2019-05-16 NI NI201900050A patent/NI201900050A/es unknown
- 2019-05-16 DO DO2019000121A patent/DOP2019000121A/es unknown
- 2019-05-16 PH PH12019501102A patent/PH12019501102A1/en unknown
- 2019-05-16 CO CONC2019/0005038A patent/CO2019005038A2/es unknown
- 2019-05-17 EC ECSENADI201935377A patent/ECSP19035377A/es unknown