JP2016531126A5 - - Google Patents
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- Publication number
- JP2016531126A5 JP2016531126A5 JP2016535486A JP2016535486A JP2016531126A5 JP 2016531126 A5 JP2016531126 A5 JP 2016531126A5 JP 2016535486 A JP2016535486 A JP 2016535486A JP 2016535486 A JP2016535486 A JP 2016535486A JP 2016531126 A5 JP2016531126 A5 JP 2016531126A5
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- JP
- Japan
- Prior art keywords
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- compound according
- compound
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- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 150000001875 compounds Chemical class 0.000 claims 20
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- 125000001072 heteroaryl group Chemical group 0.000 claims 4
- 125000004076 pyridyl group Chemical group 0.000 claims 4
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 150000002367 halogens Chemical class 0.000 claims 3
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 125000000714 pyrimidinyl group Chemical group 0.000 claims 2
- 125000001424 substituent group Chemical group 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 125000001309 chloro group Chemical group Cl* 0.000 claims 1
- 239000000824 cytostatic agent Substances 0.000 claims 1
- 230000001085 cytostatic effect Effects 0.000 claims 1
- 230000001472 cytotoxic effect Effects 0.000 claims 1
- 125000001624 naphthyl group Chemical group 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13181578 | 2013-08-23 | ||
| EP13181578.9 | 2013-08-23 | ||
| PCT/EP2014/067858 WO2015025018A1 (en) | 2013-08-23 | 2014-08-21 | New bis-amido pyridines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016531126A JP2016531126A (ja) | 2016-10-06 |
| JP2016531126A5 true JP2016531126A5 (enExample) | 2017-09-28 |
| JP6424224B2 JP6424224B2 (ja) | 2018-11-14 |
Family
ID=49003720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016535486A Active JP6424224B2 (ja) | 2013-08-23 | 2014-08-21 | 新規ビスアミドピリジン |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9249151B2 (enExample) |
| EP (1) | EP3036235B1 (enExample) |
| JP (1) | JP6424224B2 (enExample) |
| AR (1) | AR097436A1 (enExample) |
| TW (1) | TW201605827A (enExample) |
| UY (1) | UY35711A (enExample) |
| WO (1) | WO2015025018A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6783224B2 (ja) | 2014-04-04 | 2020-11-11 | デル マー ファーマシューティカルズ | 肺の非小細胞癌腫及び卵巣癌を処置するためのジアンヒドロガラクチトール及びその類縁体又は誘導体の使用 |
| AR101479A1 (es) | 2014-08-11 | 2016-12-21 | Boehringer Ingelheim Int | Derivados de 6-alquinil-piridina |
| CN109153645B (zh) | 2016-05-19 | 2022-06-21 | 勃林格殷格翰国际有限公司 | 制备6-炔基-吡啶衍生物的方法 |
| CN118436801A (zh) | 2016-05-20 | 2024-08-06 | 豪夫迈·罗氏有限公司 | Protac抗体缀合物及其使用方法 |
| JP2020515600A (ja) | 2017-03-31 | 2020-05-28 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 抗がん併用療法 |
| EP3284739A1 (de) | 2017-07-19 | 2018-02-21 | Bayer CropScience Aktiengesellschaft | Substituierte (het)arylverbindungen als schädlingsbekämpfungsmittel |
| CN113453678A (zh) | 2018-11-26 | 2021-09-28 | 德彪药业国际股份公司 | Hiv感染的联合治疗 |
| TWI894135B (zh) | 2019-01-25 | 2025-08-21 | 德商百靈佳殷格翰國際股份有限公司 | 編碼ccl21之重組棒狀病毒 |
| EP4010081A4 (en) | 2019-08-08 | 2023-07-26 | Institute For Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center | POLYTHERAPY FOR THE TREATMENT OF CANCER |
| JP2022550037A (ja) | 2019-09-25 | 2022-11-30 | デバイオファーム インターナショナル エス．エー． | 局所進行性扁平上皮癌を有する患者の治療のための投与レジメン |
| JP7406008B2 (ja) * | 2020-05-12 | 2023-12-26 | 蘇州阿尓脈生物科技有限公司 | Ｃｄｋ９阻害剤としての多環式アミド系誘導体、その調製方法及び用途 |
| JP7451765B2 (ja) * | 2020-05-12 | 2024-03-18 | 蘇州阿尓脈生物科技有限公司 | Ｃｄｋ阻害剤としてのピリジンアセトアミド系誘導体、その調製方法及び用途 |
| WO2021245111A1 (en) | 2020-06-03 | 2021-12-09 | Boehringer Ingelheim International Gmbh | Recombinant rhabdovirus encoding for a cd80 extracellular domain fc-fusion protein |
| WO2023056069A1 (en) | 2021-09-30 | 2023-04-06 | Angiex, Inc. | Degrader-antibody conjugates and methods of using same |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005231956B2 (en) * | 2004-04-07 | 2009-11-05 | Novartis Ag | Inhibitors of IAP |
| RU2009125620A (ru) | 2006-12-07 | 2011-01-20 | Новартис АГ (CH) | Органические соединения |
| WO2008133192A1 (ja) * | 2007-04-19 | 2008-11-06 | Takeda Pharmaceutical Company Limited | 縮合イミダゾール化合物およびその用途 |
| DE102007036075A1 (de) * | 2007-08-01 | 2009-02-05 | Bayer Healthcare Ag | Prodrugs und ihre Verwendung |
| US20110117081A1 (en) * | 2008-05-05 | 2011-05-19 | Aegera Therapeutics, Inc. | Functionalized pyrrolidines and use thereof as iap inhibitors |
| TWI625121B (zh) * | 2009-07-13 | 2018-06-01 | 基利科學股份有限公司 | 調節細胞凋亡信號之激酶的抑制劑 |
-
2014
- 2014-08-20 US US14/463,690 patent/US9249151B2/en active Active
- 2014-08-21 JP JP2016535486A patent/JP6424224B2/ja active Active
- 2014-08-21 WO PCT/EP2014/067858 patent/WO2015025018A1/en not_active Ceased
- 2014-08-21 UY UY35711A patent/UY35711A/es unknown
- 2014-08-21 EP EP14755650.0A patent/EP3036235B1/en active Active
- 2014-08-22 TW TW103129096A patent/TW201605827A/zh unknown
- 2014-08-22 AR ARP140103171A patent/AR097436A1/es unknown
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