JP2016531126A5 - - Google Patents
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- Publication number
- JP2016531126A5 JP2016531126A5 JP2016535486A JP2016535486A JP2016531126A5 JP 2016531126 A5 JP2016531126 A5 JP 2016531126A5 JP 2016535486 A JP2016535486 A JP 2016535486A JP 2016535486 A JP2016535486 A JP 2016535486A JP 2016531126 A5 JP2016531126 A5 JP 2016531126A5
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- JP
- Japan
- Prior art keywords
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- compound according
- compound
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- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 150000001875 compounds Chemical class 0.000 claims 20
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- 125000001072 heteroaryl group Chemical group 0.000 claims 4
- 125000004076 pyridyl group Chemical group 0.000 claims 4
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 150000002367 halogens Chemical class 0.000 claims 3
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 125000000714 pyrimidinyl group Chemical group 0.000 claims 2
- 125000001424 substituent group Chemical group 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 125000001309 chloro group Chemical group Cl* 0.000 claims 1
- 239000000824 cytostatic agent Substances 0.000 claims 1
- 230000001085 cytostatic effect Effects 0.000 claims 1
- 230000001472 cytotoxic effect Effects 0.000 claims 1
- 125000001624 naphthyl group Chemical group 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13181578 | 2013-08-23 | ||
| EP13181578.9 | 2013-08-23 | ||
| PCT/EP2014/067858 WO2015025018A1 (en) | 2013-08-23 | 2014-08-21 | New bis-amido pyridines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016531126A JP2016531126A (ja) | 2016-10-06 |
| JP2016531126A5 true JP2016531126A5 (enExample) | 2017-09-28 |
| JP6424224B2 JP6424224B2 (ja) | 2018-11-14 |
Family
ID=49003720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016535486A Active JP6424224B2 (ja) | 2013-08-23 | 2014-08-21 | 新規ビスアミドピリジン |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9249151B2 (enExample) |
| EP (1) | EP3036235B1 (enExample) |
| JP (1) | JP6424224B2 (enExample) |
| AR (1) | AR097436A1 (enExample) |
| TW (1) | TW201605827A (enExample) |
| UY (1) | UY35711A (enExample) |
| WO (1) | WO2015025018A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2946538A1 (en) | 2014-04-04 | 2015-10-08 | Del Mar Pharmaceuticals | Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer |
| AR101479A1 (es) | 2014-08-11 | 2016-12-21 | Boehringer Ingelheim Int | Derivados de 6-alquinil-piridina |
| WO2017198734A1 (en) | 2016-05-19 | 2017-11-23 | Boehringer Ingelheim International Gmbh | Process for the manufacture of 6-alkynyl-pyridine derivatives |
| CN118436801A (zh) | 2016-05-20 | 2024-08-06 | 豪夫迈·罗氏有限公司 | Protac抗体缀合物及其使用方法 |
| CN110475567A (zh) | 2017-03-31 | 2019-11-19 | 勃林格殷格翰国际有限公司 | 抗癌组合疗法 |
| EP3284739A1 (de) | 2017-07-19 | 2018-02-21 | Bayer CropScience Aktiengesellschaft | Substituierte (het)arylverbindungen als schädlingsbekämpfungsmittel |
| CN113453678A (zh) | 2018-11-26 | 2021-09-28 | 德彪药业国际股份公司 | Hiv感染的联合治疗 |
| TWI894135B (zh) | 2019-01-25 | 2025-08-21 | 德商百靈佳殷格翰國際股份有限公司 | 編碼ccl21之重組棒狀病毒 |
| EP4010081A4 (en) | 2019-08-08 | 2023-07-26 | Institute For Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center | POLYTHERAPY FOR THE TREATMENT OF CANCER |
| WO2021058794A1 (en) | 2019-09-25 | 2021-04-01 | Debiopharm International S.A. | Dosing regimens for treatment of patients with locally advanced squamous cell carcinoma |
| WO2021227904A1 (zh) * | 2020-05-12 | 2021-11-18 | 苏州阿尔脉生物科技有限公司 | 一种作为cdk9抑制剂的多环酰胺类衍生物、其制备方法及用途 |
| US20230219961A1 (en) * | 2020-05-12 | 2023-07-13 | Suzhou Alphama Biotechnology Co., Ltd. | Pyridine acetamide derivative serving as CDK inhibitor, and preparation method therefor and use thereof |
| JP7565384B2 (ja) | 2020-06-03 | 2024-10-10 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ＣＤ８０細胞外ドメインＦｃ融合タンパク質をコードするリコンビナントラブドウイルス |
| WO2023056069A1 (en) | 2021-09-30 | 2023-04-06 | Angiex, Inc. | Degrader-antibody conjugates and methods of using same |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS52545B (sr) * | 2004-04-07 | 2013-04-30 | Novartis Ag | Inhibitori protein apoptoze (iap) |
| CN101595093A (zh) * | 2006-12-07 | 2009-12-02 | 诺瓦提斯公司 | 有机化合物 |
| WO2008133192A1 (ja) * | 2007-04-19 | 2008-11-06 | Takeda Pharmaceutical Company Limited | 縮合イミダゾール化合物およびその用途 |
| DE102007036075A1 (de) * | 2007-08-01 | 2009-02-05 | Bayer Healthcare Ag | Prodrugs und ihre Verwendung |
| WO2009136290A1 (en) * | 2008-05-05 | 2009-11-12 | Aegera Therapeutics, Inc. | Functionalized pyrrolidines and use thereof as iap inhibitors |
| TWI598347B (zh) * | 2009-07-13 | 2017-09-11 | 基利科學股份有限公司 | 調節細胞凋亡信號之激酶的抑制劑 |
-
2014
- 2014-08-20 US US14/463,690 patent/US9249151B2/en active Active
- 2014-08-21 UY UY35711A patent/UY35711A/es unknown
- 2014-08-21 JP JP2016535486A patent/JP6424224B2/ja active Active
- 2014-08-21 WO PCT/EP2014/067858 patent/WO2015025018A1/en not_active Ceased
- 2014-08-21 EP EP14755650.0A patent/EP3036235B1/en active Active
- 2014-08-22 AR ARP140103171A patent/AR097436A1/es unknown
- 2014-08-22 TW TW103129096A patent/TW201605827A/zh unknown
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