|
US1001159A
(en)
|
1910-07-25 |
1911-08-22 |
Elizabeth Nielsen |
Skirt-gage.
|
|
GB1472257A
(en)
|
1973-09-10 |
1977-05-04 |
Christiaens Sa A |
Derivative of 4-hydroxy-5-azacoumarin
|
|
US4866182A
(en)
|
1988-02-18 |
1989-09-12 |
Merrell Dow Pharmaceuticals Inc. |
Cardiotonic alkanoyl and aroyl oxazolones
|
|
US5338740A
(en)
|
1993-07-13 |
1994-08-16 |
Pfizer Inc. |
Angiotensin II receptor antagonists
|
|
JP3795305B2
(ja)
|
1999-07-19 |
2006-07-12 |
田辺製薬株式会社 |
医薬組成物
|
|
EP1379525B1
(en)
|
2001-02-21 |
2007-10-10 |
Nps Pharmaceuticals, Inc. |
Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
|
|
NZ527012A
(en)
|
2001-03-28 |
2005-03-24 |
Pfizer |
N-phenpropylcyclopentyl-substituted glutaramide derivatives as NEP inhibitors for FSAD
|
|
EP1424336A4
(en)
|
2001-09-03 |
2004-11-10 |
Takeda Chemical Industries Ltd |
1,3-BENZOTHIAZINE DERIVATIVES AND THEIR USE
|
|
JP2005170790A
(ja)
|
2002-01-09 |
2005-06-30 |
Ajinomoto Co Inc |
Ｎ−アルキルスルフォニル置換アミド誘導体
|
|
JP2005162612A
(ja)
|
2002-01-09 |
2005-06-23 |
Ajinomoto Co Inc |
アシルスルホンアミド誘導体
|
|
PT1490064E
(pt)
*
|
2002-02-14 |
2009-12-28 |
Pharmacia Corp |
Piridinonas substituídas como moduladores de p38 map-quinase
|
|
US20040147561A1
(en)
*
|
2002-12-27 |
2004-07-29 |
Wenge Zhong |
Pyrid-2-one derivatives and methods of use
|
|
WO2005004818A2
(en)
|
2003-07-09 |
2005-01-20 |
Imclone Systems Incorporated |
Heterocyclic compounds and their use as anticancer agents
|
|
US20060004001A1
(en)
|
2004-02-27 |
2006-01-05 |
Merz Pharma Gmbh & Co., Kgaa |
Tetrahydroquinolones and their use as modulators of metabotropic glutamate receptors
|
|
PE20060285A1
(es)
*
|
2004-03-30 |
2006-05-08 |
Aventis Pharma Inc |
Piridonas sustituidas como inhibidores de pol(adp-ribosa)-polimerasa (parp)
|
|
CA2561628C
(en)
|
2004-04-01 |
2012-05-08 |
Eli Lilly And Company |
Histamine h3 receptor agents, preparation and therapeutic uses
|
|
CN1968922A
(zh)
|
2004-06-18 |
2007-05-23 |
米伦纽姆医药公司 |
因子xa抑制剂
|
|
CN1989115B
(zh)
|
2004-07-26 |
2012-03-21 |
伊莱利利公司 |
作为组胺h3受体药物的噁唑衍生物及其制备和制药用途
|
|
EP1655283A1
(en)
|
2004-11-08 |
2006-05-10 |
Evotec OAI AG |
11beta-HSD1 Inhibitors
|
|
WO2006123165A2
(en)
*
|
2005-05-19 |
2006-11-23 |
Astex Therapeutics Limited |
Pyrimidine derivatives as hsp90 inhibitors
|
|
WO2007023242A1
(en)
|
2005-08-24 |
2007-03-01 |
Merz Pharma Gmbh & Co. Kgaa |
Tetrahydroquinolinones and their use as modulators of metabotropic glutamate receptors
|
|
AU2007208351C1
(en)
|
2006-01-23 |
2011-07-07 |
Amgen Inc. |
Aurora kinase modulators and method of use
|
|
JP2007314516A
(ja)
|
2006-04-25 |
2007-12-06 |
Daiichi Sankyo Co Ltd |
２以上の置換基を有するベンゼン化合物を含有する医薬
|
|
JP5270545B2
(ja)
|
2006-08-03 |
2013-08-21 |
タフツ ユニバーシティー／トラスティーズ オブ タフツ カレッジ |
フラッシングのないナイアシン類似体およびそれらの使用法
|
|
US20090318389A1
(en)
|
2006-08-04 |
2009-12-24 |
Praecis Pharmaceuticals Incorporated |
Agonists of the sphingosine-1 phosphate receptor
|
|
EP1894924A1
(en)
|
2006-08-29 |
2008-03-05 |
Phenex Pharmaceuticals AG |
Heterocyclic FXR binding compounds
|
|
EP2089026A2
(en)
|
2006-12-01 |
2009-08-19 |
Novartis AG |
Inhibitors of protein tyrosine phosphatase for the promotion of physiological cardiac hypertrophy
|
|
US20100152210A1
(en)
|
2007-03-28 |
2010-06-17 |
Neuro Search A/S/ |
Purinyl derivatives and their use as potassium channel modulators
|
|
WO2009067621A1
(en)
*
|
2007-11-21 |
2009-05-28 |
Decode Genetics Ehf |
Biaryl pde4 inhibitors for treating pulmonary and cardiovascular disorders
|
|
WO2009093264A2
(en)
|
2008-01-25 |
2009-07-30 |
Torrent Pharmaceuticals Ltd. |
Pharmaceutical combinations
|
|
CA2721060A1
(en)
|
2008-04-09 |
2009-10-15 |
Infinity Pharmaceuticals, Inc. |
Inhibitors of fatty acid amide hydrolase
|
|
CN102047061A
(zh)
|
2008-05-30 |
2011-05-04 |
福斯特韦勒能源股份公司 |
通过氧化燃料燃烧发电的方法和系统
|
|
BRPI0914942A2
(pt)
|
2008-06-30 |
2015-08-11 |
Cylene Pharmaceuticals Inc |
Compostos de oxindol
|
|
EP2351743A4
(en)
|
2008-10-27 |
2012-05-09 |
Takeda Pharmaceutical |
BICYCLIC COMPOUND
|
|
CN103396474A
(zh)
*
|
2008-11-04 |
2013-11-20 |
安科治疗公司 |
Apj受体化合物
|
|
BR112012006630A2
(pt)
|
2009-09-24 |
2016-05-03 |
Hoffmann La Roche |
derivados em indol como moduladores dos canais de cálcio ativados para liberação de cálcio (crac)
|
|
AU2010299928A1
(en)
|
2009-09-24 |
2012-02-02 |
F. Hoffmann-La Roche Ag |
Heterocyclic antiviral compounds
|
|
WO2011062955A2
(en)
|
2009-11-18 |
2011-05-26 |
University Of Massachusetts |
Compounds for modulating tlr2
|
|
SG181811A1
(en)
|
2009-12-18 |
2012-07-30 |
Activesite Pharmaceuticals Inc |
Prodrugs of inhibitors of plasma kallikrein
|
|
CN102241621A
(zh)
|
2010-05-11 |
2011-11-16 |
江苏恒瑞医药股份有限公司 |
5,5-双取代-2-亚氨基吡咯烷类衍生物、其制备方法及其在医药上的应用
|
|
CN102906074A
(zh)
|
2010-05-24 |
2013-01-30 |
东亚荣养株式会社 |
稠合咪唑衍生物
|
|
US9187437B2
(en)
*
|
2010-09-24 |
2015-11-17 |
Bristol-Myers Squibb Company |
Substituted oxadiazole compounds
|
|
JPWO2012074022A1
(ja)
|
2010-12-01 |
2014-05-19 |
旭硝子株式会社 |
イリジウムカチオン錯体および発光組成物
|
|
US20140057953A1
(en)
|
2011-03-03 |
2014-02-27 |
Rolf Hartmann |
Biaryl derivatives as selective 17beta-hydroxysteroid dehydrogenase type 2 inhibitors
|
|
WO2012142308A1
(en)
|
2011-04-13 |
2012-10-18 |
Activesite Pharmaceuticals, Inc. |
Prodrugs of inhibitors of plasma kallikrein
|
|
US9156830B2
(en)
|
2011-05-17 |
2015-10-13 |
Shionogi & Co., Ltd. |
Heterocyclic compounds
|
|
KR20140115329A
(ko)
|
2011-12-23 |
2014-09-30 |
바스프 에스이 |
무척추동물 해충 퇴치를 위한 이소티아졸린 화합물
|
|
EP2844655A1
(en)
*
|
2012-05-02 |
2015-03-11 |
Lupin Limited |
Substituted pyridine compounds as crac modulators
|
|
BR112014027133A2
(pt)
|
2012-05-09 |
2017-06-27 |
Basf Se |
compostos, composição agrícola ou veterinária, método para o controle das pragas de invertebrados, material de propagação dos vegetais e método para o tratamento ou proteção de um animal.
|
|
CA2875305C
(en)
|
2012-06-08 |
2021-06-01 |
University Of Pittsburgh - Of The Commonwealth System Of Higher Education |
Fbxo3 inhibitors
|
|
EP2866803A1
(en)
|
2012-07-02 |
2015-05-06 |
Max-Delbrück-Centrum für Molekulare Medizin Berlin-Buch |
Psoralen derivatives for preventing or treating heart failure or cardiac hypertrophy
|
|
CN103570625A
(zh)
|
2012-07-19 |
2014-02-12 |
南京英派药业有限公司 |
N-(3-杂芳基芳基)-4-芳基芳基甲酰胺和类似物作为Hedgehog通路抑制剂及其应用
|
|
EP2888256A4
(en)
|
2012-08-24 |
2016-02-17 |
Univ Texas |
HETEROCYCLIC HIF ACTIVITY MODULATORS FOR THE TREATMENT OF DISEASES
|
|
HUE031733T2
(en)
*
|
2012-09-21 |
2017-07-28 |
Sanofi Sa |
Benzimidazole carboxylic acid amide derivatives for the treatment of metabolic or cardiovascular diseases
|
|
WO2014062938A1
(en)
|
2012-10-19 |
2014-04-24 |
Bristol-Myers Squibb Company |
Rory modulators
|
|
US10201623B2
(en)
|
2013-03-15 |
2019-02-12 |
Memorial Sloan Kettering Cancer Center |
HSP90-targeted cardiac imaging and therapy
|
|
US9751881B2
(en)
|
2013-07-31 |
2017-09-05 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
JP6199197B2
(ja)
|
2014-02-07 |
2017-09-20 |
花王株式会社 |
ポリオキシアルキレンアルキルエーテルカルボン酸塩の製造方法
|
|
JP2017071553A
(ja)
|
2014-02-25 |
2017-04-13 |
味の素株式会社 |
ヘテロ原子−メチレン−ヘテロ環構造を有する新規化合物
|
|
JP6552061B2
(ja)
|
2014-06-10 |
2019-07-31 |
サンフォード−バーンハム メディカル リサーチ インスティテュート |
代謝型グルタミン酸受容体の負のアロステリックモジュレーター（ｎａｍｓ）とその使用
|
|
EA201691881A1
(ru)
|
2014-09-18 |
2017-12-29 |
Байер Фарма Акциенгезельшафт |
Новые соединения
|
|
TN2017000483A1
(en)
|
2015-05-20 |
2019-04-12 |
Amgen Inc |
Triazole agonists of the apj receptor.
|
|
MY189453A
(en)
|
2015-06-03 |
2022-02-14 |
Bristol Myers Squibb Co |
4-hydroxy-3-(heteroaryl)pyridine-2-one apj agonists for use in the treatment of cardiovascular disorders
|
|
KR101711744B1
(ko)
|
2015-07-16 |
2017-03-02 |
경희대학교 산학협력단 |
옥사디아졸 유도체, 이의 제조방법 및 이를 포함하는 전자수송층
|
|
CA3001974A1
(en)
|
2015-10-14 |
2017-04-20 |
Bristol-Myers Squibb Company |
2,4-dihydroxy-nicotinamides as apj agonists
|
|
EP3380970B1
(en)
|
2015-11-24 |
2023-01-04 |
Sanford Burnham Prebys Medical Discovery Institute |
Novel azole derivatives as apelin receptor agonist
|
|
WO2017096130A1
(en)
|
2015-12-04 |
2017-06-08 |
Bristol-Myers Squibb Company |
Apelin receptor agonists and methods of use
|
|
US10100059B2
(en)
|
2015-12-09 |
2018-10-16 |
Research Triangle Institute |
Apelin receptor (APJ) agonists and uses thereof
|
|
TW201725203A
(zh)
|
2015-12-16 |
2017-07-16 |
必治妥美雅史谷比公司 |
作為ａｐｊ受體促效劑之雜芳基羥基嘧啶酮
|
|
MA43761A
(fr)
|
2016-03-24 |
2021-05-05 |
Bristol Myers Squibb Co |
6-hydroxy-4-oxo-1,4-dihydropyrimidine-5-carboxamides comme inhibiteurs de la apj
|
|
KR102521955B1
(ko)
|
2016-06-14 |
2023-04-13 |
브리스톨-마이어스 스큅 컴퍼니 |
Apj 수용체 효능제로서의 4-히드록시-3-술포닐피리딘-2(1h)-온
|
|
US10508104B2
(en)
|
2016-06-14 |
2019-12-17 |
Bristol-Myers Squibb Company |
6-hydroxy-5-(phenyl/heteroarylsulfonyl)pyrimidin-4(1H)-one as APJ agonists
|
|
EP3526198B1
(en)
|
2016-10-14 |
2020-08-12 |
Bristol-Myers Squibb Company |
3-sulfonyl-5-aminopyridine-2,4-diol apj agonists
|