|
SE0102299D0
(sv)
|
2001-06-26 |
2001-06-26 |
Astrazeneca Ab |
Compounds
|
|
SE0102764D0
(sv)
|
2001-08-17 |
2001-08-17 |
Astrazeneca Ab |
Compounds
|
|
PL375021A1
(en)
|
2002-10-03 |
2005-11-14 |
Novartis Ag |
Substituted (thiazol-2-yl) -amide or sulfonamide as glycokinase activators useful in the treatment of type 2 diabetes
|
|
GB0226931D0
(en)
|
2002-11-19 |
2002-12-24 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0226930D0
(en)
|
2002-11-19 |
2002-12-24 |
Astrazeneca Ab |
Chemical compounds
|
|
PL378117A1
(pl)
*
|
2003-02-11 |
2006-03-06 |
Prosidion Limited |
Tricyklopodstawione związki amidowe
|
|
WO2005046683A1
(en)
|
2003-10-07 |
2005-05-26 |
Renovis, Inc. |
Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
|
|
US7977322B2
(en)
|
2004-08-20 |
2011-07-12 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-binding cassette transporters
|
|
BRPI0507278A
(pt)
*
|
2004-01-30 |
2007-06-26 |
Vertex Pharma |
moduladores dos transportadores do cassete de ligação ao atp
|
|
PT1735322E
(pt)
|
2004-04-02 |
2012-01-12 |
Novartis Ag |
Derivados de sulfonamido-tiazolopiridina como activadores de glucoquinase úteis para o tratamento de diabetes de tipo 2
|
|
US7781451B2
(en)
|
2004-04-02 |
2010-08-24 |
Novartis Ag |
Thiazolopyridine derivatives, pharmaceut ical conditions containing them and methods of treating glucokinase mediated conditions
|
|
GB0418058D0
(en)
*
|
2004-08-12 |
2004-09-15 |
Prosidion Ltd |
Fluorination process
|
|
US7576099B2
(en)
|
2005-02-28 |
2009-08-18 |
Renovis, Inc. |
Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
|
|
US20080300243A1
(en)
*
|
2005-02-28 |
2008-12-04 |
Kelly Michael G |
Amide Derivatives as Ion-Channel Ligands and Pharmaceutical Compositions and Methods of Using the Same
|
|
KR20110084339A
(ko)
|
2005-07-09 |
2011-07-21 |
아스트라제네카 아베 |
당뇨병 치료에 있어 glk 활성화제로서 사용하기 위한 헤테로아릴 벤즈아미드 유도체
|
|
JP5170386B2
(ja)
|
2005-08-18 |
2013-03-27 |
日産化学工業株式会社 |
スルフォニル基を有するチオフェン化合物及びその製造法
|
|
JP2007063225A
(ja)
|
2005-09-01 |
2007-03-15 |
Takeda Chem Ind Ltd |
イミダゾピリジン化合物
|
|
NZ566877A
(en)
|
2005-09-29 |
2010-05-28 |
Sanofi Aventis |
Phenyl-1,2,4-oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals
|
|
GT200600429A
(es)
|
2005-09-30 |
2007-04-30 |
|
Compuestos organicos
|
|
GT200600428A
(es)
|
2005-09-30 |
2007-05-21 |
|
Compuestos organicos
|
|
CA2626475A1
(en)
*
|
2005-11-03 |
2007-05-10 |
Prosidion Limited |
Tricyclo substituted amides
|
|
PT2404919E
(pt)
|
2005-11-08 |
2013-10-22 |
Vertex Pharma |
Composto heterocíclico útil como um modulador de transportadores de cassete de ligação a atp
|
|
US7671221B2
(en)
|
2005-12-28 |
2010-03-02 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding Cassette transporters
|
|
EP2001875A2
(en)
|
2006-03-08 |
2008-12-17 |
Takeda San Diego, Inc. |
Glucokinase activators
|
|
PE20080251A1
(es)
|
2006-05-04 |
2008-04-25 |
Boehringer Ingelheim Int |
Usos de inhibidores de dpp iv
|
|
EP2049518B1
(en)
|
2006-05-31 |
2011-08-31 |
Takeda San Diego, Inc. |
Indazole and isoindole derivatives as glucokinase activating agents.
|
|
JP2010500300A
(ja)
|
2006-08-08 |
2010-01-07 |
サノフィ−アベンティス |
アリールアミノアリール−アルキル−置換イミダゾリジン−2,4−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用
|
|
US7754739B2
(en)
|
2007-05-09 |
2010-07-13 |
Vertex Pharmaceuticals Incorporated |
Modulators of CFTR
|
|
US7902248B2
(en)
|
2006-12-14 |
2011-03-08 |
Hoffmann-La Roche Inc. |
Oxime glucokinase activators
|
|
JP5419706B2
(ja)
|
2006-12-20 |
2014-02-19 |
タケダ カリフォルニア インコーポレイテッド |
グルコキナーゼアクチベーター
|
|
WO2008084872A1
(ja)
|
2007-01-10 |
2008-07-17 |
Mitsubishi Tanabe Pharma Corporation |
ヒドラゾン誘導体
|
|
DE102007005045B4
(de)
|
2007-01-26 |
2008-12-18 |
Sanofi-Aventis |
Phenothiazin Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
WO2008104994A2
(en)
|
2007-02-28 |
2008-09-04 |
Advinus Therapeutics Private Limited |
2,2,2-tri-substituted acetamide derivatives as glucokinase activators, their process and pharmaceutical application
|
|
WO2008116107A2
(en)
|
2007-03-21 |
2008-09-25 |
Takeda San Diego, Inc. |
Piperazine derivatives as glucokinase activators
|
|
JPWO2008136428A1
(ja)
*
|
2007-04-27 |
2010-07-29 |
武田薬品工業株式会社 |
含窒素5員複素環化合物
|
|
EP2164840A2
(en)
|
2007-05-09 |
2010-03-24 |
Vertex Pharmaceuticals Incorporated |
Modulators of cftr
|
|
EP2025674A1
(de)
|
2007-08-15 |
2009-02-18 |
sanofi-aventis |
Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
AU2008315651B2
(en)
*
|
2007-10-22 |
2012-12-13 |
Orchid Research Laboratories Limited |
Histone deacetylase inhibitors
|
|
HUE049642T2
(hu)
|
2007-12-07 |
2020-09-28 |
Vertex Pharma |
3-(6-(1-(2,2-Difluorbenzo[d][1,3]dioxol-5-il)-ciklopropánkarboxamido)-3-metilpiridin-2-il)-benzoesav szilárd formái
|
|
CA2989620C
(en)
|
2007-12-07 |
2022-05-03 |
Vertex Pharmaceuticals Incorporated |
Processes for producing cycloalkylcarboxamido-pyridine benzoic acids
|
|
AU2009205070A1
(en)
|
2008-01-18 |
2009-07-23 |
Astellas Pharma Inc. |
Phenyl acetamide derivative
|
|
CA2716109C
(en)
|
2008-02-28 |
2016-07-19 |
Vertex Pharmaceuticals Incorporated |
Heteroaryl derivatives as cftr modulators
|
|
WO2009128481A1
(ja)
*
|
2008-04-16 |
2009-10-22 |
武田薬品工業株式会社 |
含窒素5員複素環化合物
|
|
JP5513492B2
(ja)
|
2008-05-16 |
2014-06-04 |
タケダ カリフォルニア インコーポレイテッド |
グルコキナーゼ活性剤
|
|
WO2010003624A2
(en)
|
2008-07-09 |
2010-01-14 |
Sanofi-Aventis |
Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
|
|
US8410284B2
(en)
|
2008-10-22 |
2013-04-02 |
Merck Sharp & Dohme Corp |
Cyclic benzimidazole derivatives useful as anti-diabetic agents
|
|
WO2010051206A1
(en)
|
2008-10-31 |
2010-05-06 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
WO2010068601A1
(en)
|
2008-12-08 |
2010-06-17 |
Sanofi-Aventis |
A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
|
|
UA104742C2
(uk)
*
|
2008-12-19 |
2014-03-11 |
Эли Лилли Энд Компани |
Похідні арилциклопропілацетаміду, застосовні як активатори глюкокінази
|
|
WO2011011277A1
(en)
*
|
2009-07-23 |
2011-01-27 |
State Of Oregon Acting By & Through The State Board Of Higher Education On Behalf Of Oregon State University |
Inhibitor(s) of transporters or uptake of monoaminergic neurotransmitters
|
|
SG178880A1
(en)
|
2009-08-26 |
2012-04-27 |
Sanofi Sa |
Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use
|
|
JP2013520502A
(ja)
|
2010-02-25 |
2013-06-06 |
メルク・シャープ・エンド・ドーム・コーポレイション |
有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体
|
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
CA2800498C
(en)
|
2010-03-31 |
2021-11-16 |
The Scripps Research Institute |
Reprogramming cells
|
|
ES2900353T3
(es)
|
2010-04-07 |
2022-03-16 |
Vertex Pharma |
Composiciones farmacéuticas de ácido 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-il)ciclopropanocarboxamido)-3-metilpiriidin-2-il)benzoico y administración de las mismas
|
|
EP2582709B1
(de)
|
2010-06-18 |
2018-01-24 |
Sanofi |
Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
|
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
|
TW201245115A
(en)
|
2011-01-24 |
2012-11-16 |
Chdi Foundation Inc |
Histone deacetylase inhibitors and compositions and methods of use thereof
|
|
CA2826649C
(en)
|
2011-02-25 |
2016-07-26 |
Merck Sharp & Dohme Corp. |
Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents
|
|
EP2683698B1
(de)
|
2011-03-08 |
2017-10-04 |
Sanofi |
Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
WO2012120055A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
EP2766349B1
(de)
|
2011-03-08 |
2016-06-01 |
Sanofi |
Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
EP2683703B1
(de)
|
2011-03-08 |
2015-05-27 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
US8846666B2
(en)
|
2011-03-08 |
2014-09-30 |
Sanofi |
Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
|
|
EP2683704B1
(de)
|
2011-03-08 |
2014-12-17 |
Sanofi |
Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
US8809324B2
(en)
|
2011-03-08 |
2014-08-19 |
Sanofi |
Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
|
|
WO2012120054A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
WO2012120056A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
WO2013037390A1
(en)
|
2011-09-12 |
2013-03-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
EP2567959B1
(en)
|
2011-09-12 |
2014-04-16 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
EP2760862B1
(en)
|
2011-09-27 |
2015-10-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
NZ727015A
(en)
|
2012-01-25 |
2017-12-22 |
Vertex Pharma |
Formulations of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
|
|
TW201408628A
(zh)
|
2012-07-16 |
2014-03-01 |
Chdi Foundation Inc |
組蛋白去乙醯酶抑制劑及組成物,暨其使用之方法
|
|
US20140045746A1
(en)
|
2012-08-02 |
2014-02-13 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
|
JP2016516004A
(ja)
|
2013-02-22 |
2016-06-02 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
抗糖尿病二環式化合物
|
|
WO2014139388A1
(en)
|
2013-03-14 |
2014-09-18 |
Merck Sharp & Dohme Corp. |
Novel indole derivatives useful as anti-diabetic agents
|
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
|
CA2930199C
(en)
|
2013-11-12 |
2022-10-25 |
Vertex Pharmaceuticals Incorporated |
Process of preparing pharmaceutical compositions for the treatment of cftr mediated diseases
|
|
HUE055423T2
(hu)
|
2014-11-18 |
2021-11-29 |
Vertex Pharma |
Eljárás nagy áteresztõképességû tesztelõ nagy teljesítményû folyadék-kromatográfia elvégzésére
|
|
US20180327355A1
(en)
|
2015-12-04 |
2018-11-15 |
Viiv Healthcare Uk Limited |
Isoindoline derivatives
|
|
US9840481B2
(en)
|
2016-03-22 |
2017-12-12 |
Merck Sharp & Dohme Corp. |
Allosteric modulators of nicotinic acetylcholine receptors
|
|
WO2018106518A1
(en)
|
2016-12-06 |
2018-06-14 |
Merck Sharp & Dohme Corp. |
Antidiabetic heterocyclic compounds
|
|
WO2018118670A1
(en)
|
2016-12-20 |
2018-06-28 |
Merck Sharp & Dohme Corp. |
Antidiabetic spirochroman compounds
|
|
BR112021002207A2
(pt)
|
2018-08-10 |
2021-05-04 |
Diapin Therapeutics, Llc |
tri-peptídeos e tratamento de distúrbios metabólicos, cardiovasculares e inflamatórios
|