|
SE0102299D0
(sv)
|
2001-06-26 |
2001-06-26 |
Astrazeneca Ab |
Compounds
|
|
SE0102764D0
(sv)
|
2001-08-17 |
2001-08-17 |
Astrazeneca Ab |
Compounds
|
|
JP2006509774A
(ja)
|
2002-10-03 |
2006-03-23 |
ノバルティス アクチエンゲゼルシャフト |
2型糖尿病の処置において有用なグルコキナーゼアクチベーターとしての置換(チアゾール−2−イル)−アミドまたはスルホンアミド
|
|
GB0226931D0
(en)
|
2002-11-19 |
2002-12-24 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0226930D0
(en)
|
2002-11-19 |
2002-12-24 |
Astrazeneca Ab |
Chemical compounds
|
|
PL378117A1
(pl)
*
|
2003-02-11 |
2006-03-06 |
Prosidion Limited |
Tricyklopodstawione związki amidowe
|
|
WO2005046683A1
(en)
|
2003-10-07 |
2005-05-26 |
Renovis, Inc. |
Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
|
|
US7977322B2
(en)
|
2004-08-20 |
2011-07-12 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-binding cassette transporters
|
|
JP4960708B2
(ja)
*
|
2004-01-30 |
2012-06-27 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Atp結合カセットトランスポーターのモジュレーター
|
|
CN1960995B
(zh)
|
2004-04-02 |
2010-12-08 |
诺瓦提斯公司 |
作为葡糖激酶活化剂、可用于治疗ⅱ型糖尿病的磺酰胺-噻唑并吡啶衍生物
|
|
EP1737870A1
(en)
|
2004-04-02 |
2007-01-03 |
Novartis AG |
Thiazolopyridine derivates, pharmaceutical conditions containing them and methods of treating glucokinase mediated conditions
|
|
GB0418058D0
(en)
*
|
2004-08-12 |
2004-09-15 |
Prosidion Ltd |
Fluorination process
|
|
US7576099B2
(en)
|
2005-02-28 |
2009-08-18 |
Renovis, Inc. |
Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
|
|
US20080300243A1
(en)
*
|
2005-02-28 |
2008-12-04 |
Kelly Michael G |
Amide Derivatives as Ion-Channel Ligands and Pharmaceutical Compositions and Methods of Using the Same
|
|
US7642259B2
(en)
|
2005-07-09 |
2010-01-05 |
Astrazeneca Ab |
Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes
|
|
US8008425B2
(en)
|
2005-08-18 |
2011-08-30 |
Nissan Chemical Industries, Ltd. |
Thiophene compound having sulfonyl group and process for producing the same
|
|
JP2007063225A
(ja)
|
2005-09-01 |
2007-03-15 |
Takeda Chem Ind Ltd |
イミダゾピリジン化合物
|
|
JP2009509988A
(ja)
|
2005-09-29 |
2009-03-12 |
サノフィ−アベンティス |
フェニル−及びピリジニル−1,2,4−オキサジアゾロン誘導体、その製造方法、及び医薬品としてのその使用
|
|
GT200600429A
(es)
|
2005-09-30 |
2007-04-30 |
|
Compuestos organicos
|
|
GT200600428A
(es)
|
2005-09-30 |
2007-05-21 |
|
Compuestos organicos
|
|
CA2626475A1
(en)
*
|
2005-11-03 |
2007-05-10 |
Prosidion Limited |
Tricyclo substituted amides
|
|
ES2778846T3
(es)
|
2005-11-08 |
2020-08-12 |
Vertex Pharma |
Moduladores heterocíclicos de transportadores de casete de unión a ATP
|
|
US7671221B2
(en)
|
2005-12-28 |
2010-03-02 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding Cassette transporters
|
|
US8034822B2
(en)
|
2006-03-08 |
2011-10-11 |
Takeda San Diego, Inc. |
Glucokinase activators
|
|
PE20110235A1
(es)
|
2006-05-04 |
2011-04-14 |
Boehringer Ingelheim Int |
Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
|
|
US8008332B2
(en)
|
2006-05-31 |
2011-08-30 |
Takeda San Diego, Inc. |
Substituted indazoles as glucokinase activators
|
|
AU2007283113A1
(en)
|
2006-08-08 |
2008-02-14 |
Sanofi-Aventis |
Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use
|
|
US7754739B2
(en)
|
2007-05-09 |
2010-07-13 |
Vertex Pharmaceuticals Incorporated |
Modulators of CFTR
|
|
US7902248B2
(en)
|
2006-12-14 |
2011-03-08 |
Hoffmann-La Roche Inc. |
Oxime glucokinase activators
|
|
WO2008079787A2
(en)
|
2006-12-20 |
2008-07-03 |
Takeda San Diego, Inc. |
Glucokinase activators
|
|
WO2008084872A1
(ja)
|
2007-01-10 |
2008-07-17 |
Mitsubishi Tanabe Pharma Corporation |
ヒドラゾン誘導体
|
|
DE102007005045B4
(de)
|
2007-01-26 |
2008-12-18 |
Sanofi-Aventis |
Phenothiazin Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
US8940900B2
(en)
|
2007-02-28 |
2015-01-27 |
Advinus Therapeutics Private Limited |
2,2,2-tri-substituted acetamide derivatives as glucokinase activators, their process and pharmaceutical application
|
|
US8173645B2
(en)
|
2007-03-21 |
2012-05-08 |
Takeda San Diego, Inc. |
Glucokinase activators
|
|
JPWO2008136428A1
(ja)
*
|
2007-04-27 |
2010-07-29 |
武田薬品工業株式会社 |
含窒素5員複素環化合物
|
|
CN102863432B
(zh)
|
2007-05-09 |
2016-09-07 |
沃泰克斯药物股份有限公司 |
Cftr调节剂
|
|
EP2025674A1
(de)
|
2007-08-15 |
2009-02-18 |
sanofi-aventis |
Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
MX2010004402A
(es)
*
|
2007-10-22 |
2010-10-15 |
Orchid Res Lab Ltd |
Inhibidores de histona deacetilasa.
|
|
WO2009076142A2
(en)
|
2007-12-07 |
2009-06-18 |
Vertex Pharmaceuticals Incorporated |
Processes for producing cycloalkylcarboxiamido-pyridine benzoic acids
|
|
KR20150063170A
(ko)
|
2007-12-07 |
2015-06-08 |
버텍스 파마슈티칼스 인코포레이티드 |
3-(6-(1-(2,2-디플루오로벤조[d][1,3]디옥솔-5-일)사이클로프로판카복스아미도)-3-메틸피리딘-2-일)벤조산의 고체 형태
|
|
AU2009205070A1
(en)
|
2008-01-18 |
2009-07-23 |
Astellas Pharma Inc. |
Phenyl acetamide derivative
|
|
CN106432213A
(zh)
|
2008-02-28 |
2017-02-22 |
沃泰克斯药物股份有限公司 |
作为cftr调节剂的杂芳基衍生物
|
|
US8349886B2
(en)
*
|
2008-04-16 |
2013-01-08 |
Takeda Pharmaceutical Company Limited |
Nitrogenated 5-membered heterocyclic compound
|
|
TWI445707B
(zh)
|
2008-05-16 |
2014-07-21 |
Takeda California Inc |
葡萄糖激酶活化劑
|
|
UY31968A
(es)
|
2008-07-09 |
2010-01-29 |
Sanofi Aventis |
Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos
|
|
US8410284B2
(en)
|
2008-10-22 |
2013-04-02 |
Merck Sharp & Dohme Corp |
Cyclic benzimidazole derivatives useful as anti-diabetic agents
|
|
CA2741672A1
(en)
|
2008-10-31 |
2010-05-06 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
WO2010068601A1
(en)
|
2008-12-08 |
2010-06-17 |
Sanofi-Aventis |
A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
|
|
UA104742C2
(uk)
*
|
2008-12-19 |
2014-03-11 |
Эли Лилли Энд Компани |
Похідні арилциклопропілацетаміду, застосовні як активатори глюкокінази
|
|
WO2011011277A1
(en)
|
2009-07-23 |
2011-01-27 |
State Of Oregon Acting By & Through The State Board Of Higher Education On Behalf Of Oregon State University |
Inhibitor(s) of transporters or uptake of monoaminergic neurotransmitters
|
|
KR20120060207A
(ko)
|
2009-08-26 |
2012-06-11 |
사노피 |
신규한 결정성 헤테로방향족 플루오로글리코시드 수화물, 이들 화합물을 포함하는 약제 및 이들의 용도
|
|
AU2011218830B2
(en)
|
2010-02-25 |
2014-07-24 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
JP5909482B2
(ja)
|
2010-03-31 |
2016-04-26 |
ザ スクリプス リサーチ インスティテュート |
細胞の再プログラム
|
|
BR112012026255A2
(pt)
|
2010-04-07 |
2017-03-14 |
Vertex Pharma |
composições farmacêuticas de ácido 3-(6-(1-(2-,2-difluorbenzo[d][1,3]dioxol-5-il)ciclopropanocarboxamido)-3-metilpiridin-2-il)benzóico e administração das mesmas
|
|
EP2582709B1
(de)
|
2010-06-18 |
2018-01-24 |
Sanofi |
Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
|
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
|
TW201245115A
(en)
|
2011-01-24 |
2012-11-16 |
Chdi Foundation Inc |
Histone deacetylase inhibitors and compositions and methods of use thereof
|
|
CA2826649C
(en)
|
2011-02-25 |
2016-07-26 |
Merck Sharp & Dohme Corp. |
Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents
|
|
US8710050B2
(en)
|
2011-03-08 |
2014-04-29 |
Sanofi |
Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
|
|
EP2766349B1
(de)
|
2011-03-08 |
2016-06-01 |
Sanofi |
Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
EP2683704B1
(de)
|
2011-03-08 |
2014-12-17 |
Sanofi |
Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
WO2012120058A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
EP2683702B1
(de)
|
2011-03-08 |
2014-12-24 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
EP2683703B1
(de)
|
2011-03-08 |
2015-05-27 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
US8871758B2
(en)
|
2011-03-08 |
2014-10-28 |
Sanofi |
Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
|
|
US8809325B2
(en)
|
2011-03-08 |
2014-08-19 |
Sanofi |
Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
|
|
US8828994B2
(en)
|
2011-03-08 |
2014-09-09 |
Sanofi |
Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
|
|
WO2013037390A1
(en)
|
2011-09-12 |
2013-03-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
EP2567959B1
(en)
|
2011-09-12 |
2014-04-16 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
WO2013045413A1
(en)
|
2011-09-27 |
2013-04-04 |
Sanofi |
6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
DK2806859T3
(da)
|
2012-01-25 |
2019-08-05 |
Vertex Pharma |
Formuleringer af 3-(6-(1-(2.2-difluorbenzo[d][1,3]dioxol-5-yl) cyclopropancarboxamido)-3-methylpyridin-2-yl)benzoesyre
|
|
AR091773A1
(es)
|
2012-07-16 |
2015-02-25 |
Chdi Foundation Inc |
Inhibidores de la histona desacetilasa y composiciones y sus metodos de uso
|
|
RU2015106909A
(ru)
|
2012-08-02 |
2016-09-27 |
Мерк Шарп И Доум Корп. |
Антидиабетические трициклические соединения
|
|
BR112015019836A2
(pt)
|
2013-02-22 |
2017-07-18 |
Merck Sharp & Dohme |
composto, composição farmacêutica, e, uso de um composto
|
|
EP2970119B1
(en)
|
2013-03-14 |
2021-11-03 |
Merck Sharp & Dohme Corp. |
Novel indole derivatives useful as anti-diabetic agents
|
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
|
DK3068392T5
(da)
|
2013-11-12 |
2021-09-20 |
Vertex Pharma |
Fremgangsmåde til fremstilling af farmaceutiske sammensætninger til behandlingen af cftr-medierede sygdomme
|
|
WO2016081556A1
(en)
|
2014-11-18 |
2016-05-26 |
Vertex Pharmaceuticals Incorporated |
Process of conducting high throughput testing high performance liquid chromatography
|
|
EP3383864A1
(en)
|
2015-12-04 |
2018-10-10 |
ViiV Healthcare UK Limited |
Isoindoline derivatives
|
|
CR20180452A
(es)
|
2016-03-22 |
2019-02-06 |
Merck Sharp & Dohme |
Moduladores alostéricos de receptores de acetilcolina nicotícos
|
|
US11072602B2
(en)
|
2016-12-06 |
2021-07-27 |
Merck Sharp & Dohme Corp. |
Antidiabetic heterocyclic compounds
|
|
WO2018118670A1
(en)
|
2016-12-20 |
2018-06-28 |
Merck Sharp & Dohme Corp. |
Antidiabetic spirochroman compounds
|
|
WO2020033919A1
(en)
|
2018-08-10 |
2020-02-13 |
Diapin Therapeutics, Llc |
Tri-peptides and treatment of metabolic, cardiovascular and inflammatory disorders
|