|
SE0102299D0
(sv)
|
2001-06-26 |
2001-06-26 |
Astrazeneca Ab |
Compounds
|
|
SE0102764D0
(sv)
|
2001-08-17 |
2001-08-17 |
Astrazeneca Ab |
Compounds
|
|
NZ539013A
(en)
|
2002-10-03 |
2007-05-31 |
Novartis Ag |
Substituted (thiazol-2-yl) -amide or sulfonamide as glycokinase activators useful in the treatment of type 2 diabetes
|
|
GB0226930D0
(en)
|
2002-11-19 |
2002-12-24 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0226931D0
(en)
|
2002-11-19 |
2002-12-24 |
Astrazeneca Ab |
Chemical compounds
|
|
PL378117A1
(pl)
*
|
2003-02-11 |
2006-03-06 |
Prosidion Limited |
Tricyklopodstawione związki amidowe
|
|
JP4667384B2
(ja)
|
2003-10-07 |
2011-04-13 |
レノビス, インコーポレイテッド |
イオンチャネルリガンドとしてのアミド誘導体および薬学的組成物、ならびにこれらを使用する方法
|
|
US7977322B2
(en)
|
2004-08-20 |
2011-07-12 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-binding cassette transporters
|
|
CN1938279B
(zh)
*
|
2004-01-30 |
2011-09-14 |
沃泰克斯药物股份有限公司 |
Atp-结合弹夹转运蛋白调控剂
|
|
KR20070006816A
(ko)
|
2004-04-02 |
2007-01-11 |
노파르티스 아게 |
티아졸로피리딘 유도체, 이를 함유하는 제약 조성물 및글루코키나제 매개형 증상의 치료 방법
|
|
KR100830007B1
(ko)
|
2004-04-02 |
2008-05-15 |
노파르티스 아게 |
2형 당뇨병 치료에 유용한 글루코키나제 활성화제로서의술폰아미드-티아졸피리딘 유도체
|
|
GB0418058D0
(en)
*
|
2004-08-12 |
2004-09-15 |
Prosidion Ltd |
Fluorination process
|
|
MX2007009381A
(es)
*
|
2005-02-28 |
2007-09-25 |
Renovis Inc |
Derivados de amida como ligandos de canales ionicos y composiciones farmaceuticas y metodos para usar los mismos.
|
|
US7576099B2
(en)
|
2005-02-28 |
2009-08-18 |
Renovis, Inc. |
Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
|
|
NZ564608A
(en)
|
2005-07-09 |
2009-09-25 |
Astrazeneca Ab |
Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes
|
|
WO2006115305A1
(ja)
*
|
2005-08-18 |
2006-11-02 |
Nissan Chemical Industries, Ltd. |
スルフォニル基を有するチオフェン化合物及びその製造法
|
|
JP2007063225A
(ja)
|
2005-09-01 |
2007-03-15 |
Takeda Chem Ind Ltd |
イミダゾピリジン化合物
|
|
AU2006299091A1
(en)
|
2005-09-29 |
2007-04-12 |
Sanofi-Aventis |
Phenyl- and pyridinyl- 1, 2 , 4 - oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals
|
|
GT200600429A
(es)
|
2005-09-30 |
2007-04-30 |
|
Compuestos organicos
|
|
GT200600428A
(es)
|
2005-09-30 |
2007-05-21 |
|
Compuestos organicos
|
|
BRPI0618062A2
(pt)
*
|
2005-11-03 |
2011-08-16 |
Prosidion Ltd |
composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, e, processo para a preparação de um composto
|
|
SI1945632T1
(sl)
|
2005-11-08 |
2014-03-31 |
Vertex Pharmaceuticals Incorporated |
Heterocikliäśni modulatorji za prenaĺ alce z atp-vezavno kaseto
|
|
US7671221B2
(en)
|
2005-12-28 |
2010-03-02 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding Cassette transporters
|
|
JP5302012B2
(ja)
|
2006-03-08 |
2013-10-02 |
タケダ カリフォルニア インコーポレイテッド |
グルコキナーゼ活性剤
|
|
PE20080251A1
(es)
|
2006-05-04 |
2008-04-25 |
Boehringer Ingelheim Int |
Usos de inhibidores de dpp iv
|
|
ATE522518T1
(de)
|
2006-05-31 |
2011-09-15 |
Takeda San Diego Inc |
Indazol- und isoindolderivate als glucokinaseaktivierende stoffe
|
|
AU2007283113A1
(en)
|
2006-08-08 |
2008-02-14 |
Sanofi-Aventis |
Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use
|
|
US7754739B2
(en)
|
2007-05-09 |
2010-07-13 |
Vertex Pharmaceuticals Incorporated |
Modulators of CFTR
|
|
US7902248B2
(en)
|
2006-12-14 |
2011-03-08 |
Hoffmann-La Roche Inc. |
Oxime glucokinase activators
|
|
WO2008079787A2
(en)
|
2006-12-20 |
2008-07-03 |
Takeda San Diego, Inc. |
Glucokinase activators
|
|
US8314247B2
(en)
|
2007-01-10 |
2012-11-20 |
Mitsubishi Tanabe Pharma Corporation |
Hydrazone derivative
|
|
DE102007005045B4
(de)
|
2007-01-26 |
2008-12-18 |
Sanofi-Aventis |
Phenothiazin Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
JP5491871B2
(ja)
|
2007-02-28 |
2014-05-14 |
アドビナス セラピュティックス プライベート リミテッド |
グルコキナーゼ活性化因子としての2,2,2−三置換アセトアミド誘導体、その方法及び薬学的応用
|
|
US8173645B2
(en)
|
2007-03-21 |
2012-05-08 |
Takeda San Diego, Inc. |
Glucokinase activators
|
|
WO2008136428A1
(ja)
*
|
2007-04-27 |
2008-11-13 |
Takeda Pharmaceutical Company Limited |
含窒素5員複素環化合物
|
|
NZ581259A
(en)
|
2007-05-09 |
2012-07-27 |
Vertex Pharma |
Modulators of cystic fibrosis transmembrane conductance regulator
|
|
EP2025674A1
(de)
|
2007-08-15 |
2009-02-18 |
sanofi-aventis |
Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
RU2453536C2
(ru)
*
|
2007-10-22 |
2012-06-20 |
Оркид Рисерч Лабораториз Лимитед |
Ингибиторы гистондезацетилазы
|
|
AU2008333845C1
(en)
|
2007-12-07 |
2014-01-16 |
Vertex Pharmaceuticals Incorporated |
Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3] dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid
|
|
SI2639224T1
(sl)
|
2007-12-07 |
2016-12-30 |
Vertex Pharmaceuticals Incorporated |
Postopek za pripravo cikloalkilkarboksiamido-piridinskih benzojskih kislin
|
|
EP2236498A4
(en)
|
2008-01-18 |
2012-02-22 |
Astellas Pharma Inc |
PHENYLACETAMIDE DERIVATIVE
|
|
CN102245573B
(zh)
|
2008-02-28 |
2013-11-20 |
沃泰克斯药物股份有限公司 |
作为cftr调节剂的杂芳基衍生物
|
|
US8349886B2
(en)
*
|
2008-04-16 |
2013-01-08 |
Takeda Pharmaceutical Company Limited |
Nitrogenated 5-membered heterocyclic compound
|
|
GEP20135783B
(en)
|
2008-05-16 |
2013-03-11 |
Takeda California Inc |
Glucokinase activators
|
|
US8470841B2
(en)
|
2008-07-09 |
2013-06-25 |
Sanofi |
Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
|
|
US8410284B2
(en)
|
2008-10-22 |
2013-04-02 |
Merck Sharp & Dohme Corp |
Cyclic benzimidazole derivatives useful as anti-diabetic agents
|
|
EP2362731B1
(en)
|
2008-10-31 |
2016-04-06 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
WO2010068601A1
(en)
|
2008-12-08 |
2010-06-17 |
Sanofi-Aventis |
A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
|
|
UA104742C2
(uk)
*
|
2008-12-19 |
2014-03-11 |
Эли Лилли Энд Компани |
Похідні арилциклопропілацетаміду, застосовні як активатори глюкокінази
|
|
WO2011011277A1
(en)
|
2009-07-23 |
2011-01-27 |
State Of Oregon Acting By & Through The State Board Of Higher Education On Behalf Of Oregon State University |
Inhibitor(s) of transporters or uptake of monoaminergic neurotransmitters
|
|
JP2013503135A
(ja)
|
2009-08-26 |
2013-01-31 |
サノフイ |
新規な結晶性複素芳香族フルオログリコシド水和物、その化合物を含んでなる医薬及びその使用
|
|
JP2013520502A
(ja)
|
2010-02-25 |
2013-06-06 |
メルク・シャープ・エンド・ドーム・コーポレイション |
有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体
|
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
CA2800498C
(en)
|
2010-03-31 |
2021-11-16 |
The Scripps Research Institute |
Reprogramming cells
|
|
LT3150198T
(lt)
|
2010-04-07 |
2021-12-10 |
Vertex Pharmaceuticals Incorporated |
3-(6-(1-(2,2-difluorbenzo[d][1,3]dioksol-5-il) ciklopropankarboksamido)-3-metilpiridin-2-il)benzoinės rūgšties farmacinė kompozicija ir jos įvedimas
|
|
EP2582709B1
(de)
|
2010-06-18 |
2018-01-24 |
Sanofi |
Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
|
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
|
TW201245115A
(en)
|
2011-01-24 |
2012-11-16 |
Chdi Foundation Inc |
Histone deacetylase inhibitors and compositions and methods of use thereof
|
|
SG192941A1
(en)
|
2011-02-25 |
2013-09-30 |
Merck Sharp & Dohme |
Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents
|
|
WO2012120054A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
US8809324B2
(en)
|
2011-03-08 |
2014-08-19 |
Sanofi |
Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
|
|
EP2683703B1
(de)
|
2011-03-08 |
2015-05-27 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
WO2012120056A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
WO2012120058A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
EP2766349B1
(de)
|
2011-03-08 |
2016-06-01 |
Sanofi |
Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
EP2683699B1
(de)
|
2011-03-08 |
2015-06-24 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
EP2683704B1
(de)
|
2011-03-08 |
2014-12-17 |
Sanofi |
Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
EP2683698B1
(de)
|
2011-03-08 |
2017-10-04 |
Sanofi |
Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
WO2013037390A1
(en)
|
2011-09-12 |
2013-03-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
EP2567959B1
(en)
|
2011-09-12 |
2014-04-16 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
WO2013045413A1
(en)
|
2011-09-27 |
2013-04-04 |
Sanofi |
6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
TW201408628A
(zh)
|
2012-07-16 |
2014-03-01 |
Chdi Foundation Inc |
組蛋白去乙醯酶抑制劑及組成物,暨其使用之方法
|
|
WO2014022528A1
(en)
|
2012-08-02 |
2014-02-06 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
|
JP2016516004A
(ja)
|
2013-02-22 |
2016-06-02 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
抗糖尿病二環式化合物
|
|
EP2970119B1
(en)
|
2013-03-14 |
2021-11-03 |
Merck Sharp & Dohme Corp. |
Novel indole derivatives useful as anti-diabetic agents
|
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
|
BR112016010403A2
(pt)
|
2013-11-12 |
2017-08-08 |
Vertex Pharma |
Processo de preparação de composições farmacêuticas para o tratamento de doenças mediadas por cftr
|
|
CA2968130C
(en)
|
2014-11-18 |
2022-08-16 |
Vertex Pharmaceuticals Incorporated |
Process of conducting high throughput testing high performance liquid chromatography
|
|
EP3383864A1
(en)
|
2015-12-04 |
2018-10-10 |
ViiV Healthcare UK Limited |
Isoindoline derivatives
|
|
SI3433234T1
(sl)
|
2016-03-22 |
2022-01-31 |
Merck Sharp & Dohme Corp. |
Alosterični modulatorji nikotinskih acetilholinskih receptorjev
|
|
WO2018106518A1
(en)
|
2016-12-06 |
2018-06-14 |
Merck Sharp & Dohme Corp. |
Antidiabetic heterocyclic compounds
|
|
WO2018118670A1
(en)
|
2016-12-20 |
2018-06-28 |
Merck Sharp & Dohme Corp. |
Antidiabetic spirochroman compounds
|