MA46860A - Inhibiteurs de magl - Google Patents
Inhibiteurs de maglInfo
- Publication number
- MA46860A MA46860A MA046860A MA46860A MA46860A MA 46860 A MA46860 A MA 46860A MA 046860 A MA046860 A MA 046860A MA 46860 A MA46860 A MA 46860A MA 46860 A MA46860 A MA 46860A
- Authority
- MA
- Morocco
- Prior art keywords
- magl inhibitors
- magl
- inhibitors
- Prior art date
Links
- 102100029814 Monoglyceride lipase Human genes 0.000 title 1
- 101710116393 Monoglyceride lipase Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662423095P | 2016-11-16 | 2016-11-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA46860A true MA46860A (fr) | 2019-09-25 |
Family
ID=62107273
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA046860A MA46860A (fr) | 2016-11-16 | 2017-11-15 | Inhibiteurs de magl |
Country Status (27)
Country | Link |
---|---|
US (1) | US9981930B1 (fr) |
EP (1) | EP3541822B1 (fr) |
JP (1) | JP6987859B2 (fr) |
KR (1) | KR20190077087A (fr) |
CN (1) | CN110248947B (fr) |
AR (1) | AR110088A1 (fr) |
AU (1) | AU2017361250A1 (fr) |
BR (1) | BR112019009991A2 (fr) |
CA (1) | CA3043612A1 (fr) |
CL (1) | CL2019001335A1 (fr) |
CO (1) | CO2019005038A2 (fr) |
CR (1) | CR20190243A (fr) |
DO (1) | DOP2019000121A (fr) |
EA (1) | EA201991074A1 (fr) |
EC (1) | ECSP19035377A (fr) |
ES (1) | ES2908632T3 (fr) |
IL (1) | IL266550A (fr) |
JO (1) | JOP20190105A1 (fr) |
MA (1) | MA46860A (fr) |
MX (1) | MX2019005771A (fr) |
NI (1) | NI201900050A (fr) |
PE (1) | PE20191146A1 (fr) |
PH (1) | PH12019501102A1 (fr) |
RU (1) | RU2019116514A (fr) |
TN (1) | TN2019000150A1 (fr) |
TW (1) | TW201831458A (fr) |
WO (1) | WO2018093946A1 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2800565T (pt) | 2012-01-06 | 2020-04-29 | Scripps Research Inst | Compostos de carbamato e processos para a sua preparação e utilização |
KR20180004263A (ko) | 2015-05-11 | 2018-01-10 | 어바이드 테라퓨틱스, 인크. | 염증 또는 신경병성 통증의 치료 방법 |
ES2892952T3 (es) | 2016-09-19 | 2022-02-07 | H Lundbeck As | Carbamatos de piperazina como moduladores del MAGL y/o ABHD6 y su uso |
HUE056973T2 (hu) | 2016-11-16 | 2022-04-28 | H Lundbeck As | MAGL inhibitor kristályos formája |
JOP20190107A1 (ar) * | 2016-11-16 | 2019-05-09 | Lundbeck La Jolla Research Center Inc | مثبطات أحادي أسيل جليسرول ليباز (magl) |
JOP20190108B1 (ar) | 2016-11-16 | 2023-09-17 | H Lundbeck As | تركيبات صيدلانية |
JOP20190106A1 (ar) * | 2016-11-16 | 2019-05-09 | Lundbeck La Jolla Research Center Inc | مثبطات أحادي أسيل جليسرول ليباز (magl) |
KR20200046061A (ko) | 2017-08-29 | 2020-05-06 | 룬드벡 라 졸라 리서치 센터 인코포레이티드 | 스피로사이클 화합물 및 이를 제조하고 사용하는 방법 |
MA50524A (fr) * | 2017-11-02 | 2020-09-09 | Aicuris Gmbh & Co Kg | Nouveaux indole-2-carboxamides à substitution amino-thiazole hautement actifs agissant contre le virus de l'hépatite b (vhb) |
US10570106B2 (en) | 2018-05-15 | 2020-02-25 | Lundbeck La Jolla Research Center, Inc. | MAGL inhibitors |
BR112021025516A2 (pt) * | 2020-04-21 | 2022-11-01 | H Lundbeck As | Processos para a fabricação de 4-(2-(pirrolidin-1-il)-4-(trifluorometil)benzil)piperazina-1-carboxilato de 1,1,1,3,3,3-hexafluoropropan-2-ila e da forma 2 do sal monocloridrato do mesmo |
TW202229255A (zh) | 2020-11-13 | 2022-08-01 | 丹麥商H 朗德貝克公司 | Magl抑制劑 |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1593586A (fr) | 1967-10-17 | 1970-06-01 | ||
JPS6183073A (ja) | 1984-10-01 | 1986-04-26 | Oki Electric Ind Co Ltd | 印字装置の用紙送り方法 |
WO1989011794A1 (fr) | 1988-06-07 | 1989-12-14 | Rikagaku Kenkyusho | Inhibiteur de la croissance de plantes |
AU3226993A (en) | 1991-11-27 | 1993-06-28 | E.I. Du Pont De Nemours And Company | Herbicidal acylated amino-(phenyl- or pyridinyl- or thienyl-)-phenyl derivatives |
JPH09506920A (ja) | 1993-12-22 | 1997-07-08 | シエル・インターナシヨナル・リサーチ・マートスハツペイ・ベー・ヴエー | カルバメートの製造法 |
AU7579696A (en) | 1995-11-15 | 1997-06-05 | Zeneca Limited | Herbicidal substituted pyrazole compounds |
AU3440597A (en) | 1996-07-02 | 1998-01-21 | Novartis Ag | N-phenylimino heterocyclic derivatives and their use as herbicides |
RU2167150C2 (ru) | 1998-03-25 | 2001-05-20 | Фокин Александр Васильевич | Полифторалкил-n-арилкарбаматы, обладающие антимикробной активностью |
JP2003511362A (ja) | 1999-10-04 | 2003-03-25 | ユニバーシティー オブ メディシン アンド デンティストリー オブ ニュー ジャージー | 新規カルバメートおよび尿素類 |
EP1201298A1 (fr) | 2000-10-24 | 2002-05-02 | Urea Casale S.A. | Dispositif pour la condensation de carbamate |
DE10348022A1 (de) | 2003-10-15 | 2005-05-25 | Imtm Gmbh | Neue Dipeptidylpeptidase IV-Inhibitoren zur funktionellen Beeinflussung unterschiedlicher Zellen und zur Behandlung immunologischer, entzündlicher, neuronaler und anderer Erkrankungen |
FR2864080B1 (fr) | 2003-12-23 | 2006-02-03 | Sanofi Synthelabo | Derives de 1-piperazine-et-1-homopiperazine-carboxylates, leur preparation et leur application en therapeutique |
WO2005063698A1 (fr) | 2003-12-31 | 2005-07-14 | Council Of Scientific & Industrial Research | Procede de preparation de carbamates |
EP1716130A1 (fr) | 2004-02-18 | 2006-11-02 | AstraZeneca AB | Composes acetyleniques de piperazine et leur utilisation en tant qu'antagonistes du recepteur metabotrope du glutamate |
CN101018770A (zh) * | 2004-04-07 | 2007-08-15 | 千禧药品公司 | 炎性疾病治疗用pgd2受体拮抗剂 |
EP1831218A2 (fr) | 2004-12-23 | 2007-09-12 | F.Hoffmann-La Roche Ag | Imidazo- et pyrrolo-pyridines à substitution carbamate comme inhibiteurs de protéine kinase |
ME02929B (fr) | 2004-12-30 | 2018-04-20 | Janssen Pharmaceutica Nv | Dérivés d'phénylamides de 4-(benzyl)-pipérazine-1-acide carboxylique et composés similaires en tant que modulateurs de l'hydrolase des amides d'acides gras (faah) pour le traitement de l'anxiété, de la douleur et d'autres états |
JP2009523729A (ja) | 2006-01-13 | 2009-06-25 | ピーティーシー セラピューティクス,インコーポレーテッド | C型肝炎の治療方法 |
WO2007097470A2 (fr) | 2006-02-23 | 2007-08-30 | Takeda Pharmaceutical Company Limited | Composé hétérocyclique fusionné |
AU2007337886C1 (en) | 2006-12-22 | 2014-10-16 | Astex Therapeutics Limited | Bicyclic heterocyclic compounds as FGFR inhibitors |
WO2008106047A2 (fr) | 2007-02-26 | 2008-09-04 | Kosan Biosciences Incorporated | Composés de carbamate |
JP2008239616A (ja) * | 2007-02-28 | 2008-10-09 | Iyaku Bunshi Sekkei Kenkyusho:Kk | Hdl上昇剤 |
US8188098B2 (en) | 2008-05-19 | 2012-05-29 | Hoffmann-La Roche Inc. | GPR119 receptor agonists |
CA2730610A1 (fr) | 2008-07-16 | 2010-01-21 | Schering Corporation | Derives heterocycliques bicycliques et leur utilisation comme modulateurs de gpcr |
EP2373315A4 (fr) | 2008-11-14 | 2012-06-27 | Scripps Research Inst | Procédé et composition se rapportant au ciblage de la mono-acylglycérol lipase |
AU2010229134A1 (en) | 2009-03-23 | 2011-11-10 | Msd K.K. | Novel aminopyridine derivatives having Aurora A selective inhibitory action |
UA107791C2 (en) | 2009-05-05 | 2015-02-25 | Dow Agrosciences Llc | Pesticidal compositions |
IN2012DN03890A (fr) | 2009-11-03 | 2015-09-04 | Bayer Materialscience Ag | |
FR2960875B1 (fr) | 2010-06-04 | 2012-12-28 | Sanofi Aventis | Derives de carbamates d'hexafluoroisopropyle, leur preparation et leur application en therapeutique |
JP6411895B2 (ja) | 2012-01-06 | 2018-10-24 | アジオス ファーマシューティカルズ, インコーポレイテッド | 治療活性化合物およびその使用方法 |
PT2800565T (pt) * | 2012-01-06 | 2020-04-29 | Scripps Research Inst | Compostos de carbamato e processos para a sua preparação e utilização |
US9567302B2 (en) | 2012-03-19 | 2017-02-14 | Abide Therapeutics, Inc. | Carbamate compounds and of making and using same |
US9551036B2 (en) | 2013-02-25 | 2017-01-24 | Whitehead Institute For Biomedical Research | Metabolic gene mesenchymal signatures and uses thereof |
MX2015017961A (es) | 2013-07-03 | 2016-10-14 | Abide Therapeutics Inc | Compuestos orgánicos pirrolo-pirrol carbamato y relacionados, composiciones farmacéuticas y usos médicos de los mismos. |
JP2018513119A (ja) * | 2015-03-18 | 2018-05-24 | アビデ セラピューティクス,インク. | ピペラジンカルバメート、およびピペラジンカルバメートを製造ならびに使用する方法 |
KR20180004263A (ko) * | 2015-05-11 | 2018-01-10 | 어바이드 테라퓨틱스, 인크. | 염증 또는 신경병성 통증의 치료 방법 |
WO2017143283A1 (fr) * | 2016-02-19 | 2017-08-24 | Abide Therapeutics, Inc. | Sonde de présence de monoacylglycérol lipase radiomarquée |
CN109496213B (zh) * | 2016-05-12 | 2022-03-04 | H.隆德贝克有限公司 | 螺环化合物及其制备和使用方法 |
JOP20190107A1 (ar) * | 2016-11-16 | 2019-05-09 | Lundbeck La Jolla Research Center Inc | مثبطات أحادي أسيل جليسرول ليباز (magl) |
JOP20190267A1 (ar) * | 2017-05-23 | 2019-11-18 | Lundbeck La Jolla Research Center Inc | مثبطات بيرازول magl |
-
2017
- 2017-06-16 JO JOP/2019/0105A patent/JOP20190105A1/ar unknown
- 2017-11-15 CR CR20190243A patent/CR20190243A/es unknown
- 2017-11-15 ES ES17871883T patent/ES2908632T3/es active Active
- 2017-11-15 CA CA3043612A patent/CA3043612A1/fr not_active Abandoned
- 2017-11-15 EA EA201991074A patent/EA201991074A1/ru unknown
- 2017-11-15 TN TNP/2019/000150A patent/TN2019000150A1/en unknown
- 2017-11-15 JP JP2019523589A patent/JP6987859B2/ja active Active
- 2017-11-15 US US15/814,318 patent/US9981930B1/en active Active
- 2017-11-15 WO PCT/US2017/061867 patent/WO2018093946A1/fr active Application Filing
- 2017-11-15 AR ARP170103183A patent/AR110088A1/es unknown
- 2017-11-15 KR KR1020197016859A patent/KR20190077087A/ko unknown
- 2017-11-15 MA MA046860A patent/MA46860A/fr unknown
- 2017-11-15 CN CN201780083635.4A patent/CN110248947B/zh active Active
- 2017-11-15 EP EP17871883.9A patent/EP3541822B1/fr active Active
- 2017-11-15 PE PE2019001015A patent/PE20191146A1/es unknown
- 2017-11-15 AU AU2017361250A patent/AU2017361250A1/en not_active Abandoned
- 2017-11-15 BR BR112019009991A patent/BR112019009991A2/pt not_active Application Discontinuation
- 2017-11-15 MX MX2019005771A patent/MX2019005771A/es unknown
- 2017-11-15 RU RU2019116514A patent/RU2019116514A/ru not_active Application Discontinuation
- 2017-11-16 TW TW106139750A patent/TW201831458A/zh unknown
-
2019
- 2019-05-12 IL IL266550A patent/IL266550A/en unknown
- 2019-05-16 CL CL2019001335A patent/CL2019001335A1/es unknown
- 2019-05-16 CO CONC2019/0005038A patent/CO2019005038A2/es unknown
- 2019-05-16 PH PH12019501102A patent/PH12019501102A1/en unknown
- 2019-05-16 NI NI201900050A patent/NI201900050A/es unknown
- 2019-05-16 DO DO2019000121A patent/DOP2019000121A/es unknown
- 2019-05-17 EC ECSENADI201935377A patent/ECSP19035377A/es unknown
Also Published As
Publication number | Publication date |
---|---|
MX2019005771A (es) | 2019-12-05 |
AU2017361250A1 (en) | 2019-05-30 |
TW201831458A (zh) | 2018-09-01 |
RU2019116514A (ru) | 2020-12-17 |
CR20190243A (es) | 2019-06-26 |
US20180134675A1 (en) | 2018-05-17 |
EP3541822B1 (fr) | 2022-01-19 |
NI201900050A (es) | 2019-10-30 |
CN110248947B (zh) | 2022-04-01 |
US9981930B1 (en) | 2018-05-29 |
JP6987859B2 (ja) | 2022-01-05 |
JOP20190105A1 (ar) | 2019-05-09 |
BR112019009991A2 (pt) | 2019-08-27 |
PE20191146A1 (es) | 2019-09-02 |
CN110248947A (zh) | 2019-09-17 |
EP3541822A4 (fr) | 2020-04-29 |
KR20190077087A (ko) | 2019-07-02 |
CO2019005038A2 (es) | 2019-05-31 |
TN2019000150A1 (en) | 2020-10-05 |
CA3043612A1 (fr) | 2018-05-24 |
AR110088A1 (es) | 2019-02-20 |
IL266550A (en) | 2019-07-31 |
DOP2019000121A (es) | 2019-09-30 |
ES2908632T3 (es) | 2022-05-03 |
PH12019501102A1 (en) | 2019-08-19 |
EA201991074A1 (ru) | 2019-12-30 |
ECSP19035377A (es) | 2019-05-31 |
CL2019001335A1 (es) | 2019-10-04 |
JP2020502047A (ja) | 2020-01-23 |
EP3541822A1 (fr) | 2019-09-25 |
WO2018093946A1 (fr) | 2018-05-24 |
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