MA46857A - Inhibiteurs de magl - Google Patents

Inhibiteurs de magl

Info

Publication number
MA46857A
MA46857A MA046857A MA46857A MA46857A MA 46857 A MA46857 A MA 46857A MA 046857 A MA046857 A MA 046857A MA 46857 A MA46857 A MA 46857A MA 46857 A MA46857 A MA 46857A
Authority
MA
Morocco
Prior art keywords
magl inhibitors
magl
inhibitors
Prior art date
Application number
MA046857A
Other languages
English (en)
Inventor
Daniel J Buzard
Cheryl A Grice
Michael B Shaghafi
Original Assignee
Abide Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abide Therapeutics Inc filed Critical Abide Therapeutics Inc
Publication of MA46857A publication Critical patent/MA46857A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/195—Radicals derived from nitrogen analogues of carboxylic acids
MA046857A 2016-11-16 2017-11-15 Inhibiteurs de magl MA46857A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662423099P 2016-11-16 2016-11-16

Publications (1)

Publication Number Publication Date
MA46857A true MA46857A (fr) 2019-09-25

Family

ID=62106678

Family Applications (1)

Application Number Title Priority Date Filing Date
MA046857A MA46857A (fr) 2016-11-16 2017-11-15 Inhibiteurs de magl

Country Status (29)

Country Link
US (1) US10093635B2 (fr)
EP (1) EP3541821A4 (fr)
JP (1) JP7042547B2 (fr)
KR (1) KR20190077544A (fr)
CN (1) CN110267963B (fr)
AR (1) AR110089A1 (fr)
AU (1) AU2017361251B2 (fr)
BR (1) BR112019009994A2 (fr)
CA (1) CA3043615A1 (fr)
CL (1) CL2019001339A1 (fr)
CO (1) CO2019005059A2 (fr)
CR (1) CR20190241A (fr)
DO (1) DOP2019000122A (fr)
EA (1) EA038090B1 (fr)
EC (1) ECSP19035077A (fr)
GE (1) GEP20237470B (fr)
IL (1) IL266523B (fr)
JO (1) JOP20190106A1 (fr)
MA (1) MA46857A (fr)
MX (1) MX2019005776A (fr)
NI (1) NI201900051A (fr)
PE (1) PE20191144A1 (fr)
PH (1) PH12019501097A1 (fr)
RU (1) RU2754536C1 (fr)
TN (1) TN2019000153A1 (fr)
TW (1) TWI756299B (fr)
UA (1) UA124542C2 (fr)
WO (1) WO2018093947A1 (fr)
ZA (1) ZA201903100B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
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PT2800565T (pt) 2012-01-06 2020-04-29 Scripps Research Inst Compostos de carbamato e processos para a sua preparação e utilização
CN113413387A (zh) 2015-05-11 2021-09-21 H.隆德贝克有限公司 治疗炎症或神经性疼痛的方法
EP3515897B1 (fr) 2016-09-19 2021-08-18 H. Lundbeck A/S Carbamates de pipérazine comme modulateurs de magl et/ou de abhd6 et leur utilisation
MA46867A (fr) 2016-11-16 2019-09-25 Abide Therapeutics Inc Formulations pharmaceutiques
JOP20190107A1 (ar) 2016-11-16 2019-05-09 Lundbeck La Jolla Research Center Inc مثبطات أحادي أسيل جليسرول ليباز (magl)
LT3541807T (lt) 2016-11-16 2021-12-27 H. Lundbeck A/S Magl inhibitoriaus kristalinė forma
FI3630744T3 (fi) 2017-05-23 2023-03-21 H Lundbeck As MAGL:n pyratsoli-inhibiittoreita
MX2020002251A (es) 2017-08-29 2020-07-20 Lundbeck La Jolla Research Center Inc Compuestos espirociclicos y sus metodos de preparacion y uso.
EP3793547A4 (fr) 2018-05-15 2021-11-17 H. Lundbeck A/S Inhibiteurs de magl
MA54827A (fr) * 2019-01-25 2022-05-04 H Lundbeck As Méthodes de traitement d'une maladie à l'aide d'inhibiteurs de magl
BR112021013917A2 (pt) * 2019-11-15 2022-05-24 H Lundbeck As Forma cristalina de um inibidor de magl, composição farmacêutica e uso
IT202000007150A1 (it) * 2020-04-03 2021-10-03 Univ Pisa Inibitori di monoacilglicerolo lipasi (magl)
CA3175210A1 (fr) 2020-04-21 2021-10-28 Cheryl A. Grice Synthese d'un inhibiteur de monoacylglycerol lipase

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WO1989011794A1 (fr) 1988-06-07 1989-12-14 Rikagaku Kenkyusho Inhibiteur de la croissance de plantes
DE69211015T2 (de) 1991-11-27 1997-01-09 Du Pont Herbizide acylierte amino-(phenyl-oder-pyridinyl-oder thienyl-)phenyl derivate
WO1995017439A2 (fr) 1993-12-22 1995-06-29 Shell Internationale Research Maatschappij B.V. Procede de preparation de carbamates
AU7579696A (en) 1995-11-15 1997-06-05 Zeneca Limited Herbicidal substituted pyrazole compounds
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EP2411010B1 (fr) 2009-03-23 2013-11-06 Msd K.K. Nouveaux dérivés d'aminopyridine présentant une action inhibitrice sélective de l'aurora a
RU2011147200A (ru) 2009-04-22 2013-05-27 Янссен Фармацевтика Нв Азетидинилдиамиды в качестве ингибиторов моноациглицерин-липазы
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KR101727770B1 (ko) 2009-11-03 2017-04-17 코베스트로 도이칠란드 아게 광중합체 제제 중의 첨가제로서의 플루오로우레탄
FR2960875B1 (fr) 2010-06-04 2012-12-28 Sanofi Aventis Derives de carbamates d'hexafluoroisopropyle, leur preparation et leur application en therapeutique
KR101893112B1 (ko) 2012-01-06 2018-08-30 아지오스 파마슈티컬스 아이엔씨. 치료학적으로 활성인 화합물 및 이의 이용 방법
PT2800565T (pt) * 2012-01-06 2020-04-29 Scripps Research Inst Compostos de carbamato e processos para a sua preparação e utilização
CN104379578B (zh) 2012-03-19 2017-06-09 阿比德治疗公司 氨基甲酸酯化合物及其制备和使用方法
JP2014005245A (ja) 2012-06-26 2014-01-16 Dainippon Sumitomo Pharma Co Ltd 二環性ピリミジン誘導体を含有する医薬組成物
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JP6647592B2 (ja) * 2013-07-03 2020-02-14 ルンドベック ラ ホーヤ リサーチ センター，インク． ピロロピロールカルバメート、および関連する有機化合物、医薬組成物、ならびにその医学的使用
US10570146B2 (en) 2014-07-25 2020-02-25 Northeastern University Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof
CN107660199B (zh) 2015-03-18 2021-11-23 H.隆德贝克有限公司 哌嗪氨基甲酸酯及其制备和使用方法
EP3515897B1 (fr) 2016-09-19 2021-08-18 H. Lundbeck A/S Carbamates de pipérazine comme modulateurs de magl et/ou de abhd6 et leur utilisation
JOP20190105A1 (ar) 2016-11-16 2019-05-09 Lundbeck La Jolla Research Center Inc مثبطات أحادي أسيل جليسرول ليباز (magl)

Also Published As

Publication number Publication date
JP7042547B2 (ja) 2022-03-28
CA3043615A1 (fr) 2018-05-24
PH12019501097A1 (en) 2019-08-19
EP3541821A4 (fr) 2020-04-22
MX2019005776A (es) 2019-12-05
CR20190241A (es) 2019-09-02
IL266523B (en) 2022-09-01
CN110267963B (zh) 2022-04-01
CO2019005059A2 (es) 2019-05-31
GEP20237470B (en) 2023-02-10
NZ753264A (en) 2020-12-18
TW201823216A (zh) 2018-07-01
JOP20190106A1 (ar) 2019-05-09
US20180134674A1 (en) 2018-05-17
TN2019000153A1 (en) 2020-10-05
ECSP19035077A (es) 2019-05-31
AU2017361251A1 (en) 2019-05-30
EA038090B1 (ru) 2021-07-05
BR112019009994A2 (pt) 2019-08-27
US10093635B2 (en) 2018-10-09
AU2017361251B2 (en) 2021-08-19
IL266523A (en) 2019-07-31
CL2019001339A1 (es) 2019-10-04
UA124542C2 (uk) 2021-10-05
RU2754536C1 (ru) 2021-09-03
DOP2019000122A (es) 2019-09-30
TWI756299B (zh) 2022-03-01
EA201991073A1 (ru) 2019-12-30
AR110089A1 (es) 2019-02-20
KR20190077544A (ko) 2019-07-03
PE20191144A1 (es) 2019-09-02
EP3541821A1 (fr) 2019-09-25
NI201900051A (es) 2019-10-30
CN110267963A (zh) 2019-09-20
WO2018093947A1 (fr) 2018-05-24
JP2020504707A (ja) 2020-02-13
RU2019116512A (ru) 2020-12-17
ZA201903100B (en) 2020-11-25

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