JP2009501745A5 - - Google Patents
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- Publication number
- JP2009501745A5 JP2009501745A5 JP2008521869A JP2008521869A JP2009501745A5 JP 2009501745 A5 JP2009501745 A5 JP 2009501745A5 JP 2008521869 A JP2008521869 A JP 2008521869A JP 2008521869 A JP2008521869 A JP 2008521869A JP 2009501745 A5 JP2009501745 A5 JP 2009501745A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- alkoxy
- substituted
- compound according
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0514812.7A GB0514812D0 (en) | 2005-07-19 | 2005-07-19 | Compounds |
| PCT/EP2006/007036 WO2007009741A1 (en) | 2005-07-19 | 2006-07-17 | Piperazinone derivatives useful as histamine h3 receptor antagonists and/or inverse agonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009501745A JP2009501745A (ja) | 2009-01-22 |
| JP2009501745A5 true JP2009501745A5 (enExample) | 2009-09-10 |
Family
ID=34897470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008521869A Pending JP2009501745A (ja) | 2005-07-19 | 2006-07-17 | ヒスタミンｈ３受容体アンタゴニストおよび／または逆アゴニストとして有用なピペラジノン誘導体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20080275027A1 (enExample) |
| EP (1) | EP1906964A1 (enExample) |
| JP (1) | JP2009501745A (enExample) |
| GB (1) | GB0514812D0 (enExample) |
| WO (1) | WO2007009741A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0514811D0 (en) * | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
| MX2009011787A (es) | 2007-05-03 | 2009-11-13 | Cephalon Inc | Procesos para preparar (r)-2-metilpirrolidina y (s)-2-metilpirrolidina y sales de tartrato de las mismas. |
| MX2010005225A (es) * | 2007-11-13 | 2010-05-27 | Taisho Pharmaceutical Co Ltd | Derivados de fenilpirazol. |
| BRPI0820481A2 (pt) | 2007-11-20 | 2015-06-16 | Janssen Pharmaceutica Nv | Composotos cicloalquilóxi e heterocicloalquilóxi piridina como moduladores do receptor de h3 de histamina |
| US20090131417A1 (en) * | 2007-11-20 | 2009-05-21 | Letavic Michael A | Substituted pyridyl amide compounds as modulators of the histamine h3 receptor |
| CN102137858B (zh) | 2008-05-23 | 2014-07-23 | 潘米拉制药有限责任公司 | 5-脂氧合酶-活化蛋白抑制剂 |
| JP5740838B2 (ja) * | 2009-05-12 | 2015-07-01 | 大正製薬株式会社 | フェニルピラゾール誘導体 |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| WO2015173701A2 (en) | 2014-05-12 | 2015-11-19 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pharmaceutical compositions for treating infectious diseases |
| WO2016028971A1 (en) | 2014-08-21 | 2016-02-25 | Bristol-Myers Squibb Company | Tied-back benzamide derivatives as potent rock inhibitors |
| HK1257102A1 (zh) * | 2015-08-21 | 2019-10-11 | Portola Pharmaceuticals, Inc. | 苯基哌嗪前蛋白转化酶枯草杆菌蛋白酶/kexin9型(pcsk9)调节剂及其应用 |
| EP3337497B1 (en) | 2015-08-21 | 2023-07-12 | SRX Cardio, LLC | Composition and methods of use of novel phenylalanine small organic compounds to directly modulate pcsk9 protein activity |
| WO2017034990A1 (en) | 2015-08-21 | 2017-03-02 | Portola Pharmaceuticals, Inc. | Composition and methods of use of tetrahydroisoquinoline small molecules to bind and modulate pcsk9 protein activity |
| US20190119236A1 (en) | 2016-02-23 | 2019-04-25 | Portola Pharmaceuticals, Inc. | Compounds for binding proprotein convertase subtilisin/kexin type 9 (pcsk9) |
| CN108486155A (zh) * | 2018-04-27 | 2018-09-04 | 中国医学科学院输血研究所 | 构建Doxycycline/Mifepristone诱导过表达的带有荧光蛋白标记基因的双诱导表达载体 |
| BR112022019245A2 (pt) | 2020-03-26 | 2022-11-16 | Glaxosmithkline Ip Dev Ltd | Inibidores de catepsina para prevenir ou tratar infecções virais |
| US12115154B2 (en) | 2020-12-16 | 2024-10-15 | Srx Cardio, Llc | Compounds for the modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4516717B2 (ja) * | 2000-07-13 | 2010-08-04 | アボット・ラボラトリーズ | ヒスタミン−３受容体リガンドとしての１，３−二置換ピロリジン及び１，３，３−三置換ピロリジン並びにそれらの治療的応用 |
| GB0224084D0 (en) * | 2002-10-16 | 2002-11-27 | Glaxo Group Ltd | Novel compounds |
| EP1554260A1 (en) * | 2002-10-22 | 2005-07-20 | Glaxo Group Limited | Aryloxyalkylamine derivatives as h3 receptor ligands |
| GB0308333D0 (en) * | 2003-04-10 | 2003-05-14 | Glaxo Group Ltd | Novel compounds |
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2005
- 2005-07-19 GB GBGB0514812.7A patent/GB0514812D0/en not_active Ceased
-
2006
- 2006-07-17 EP EP06762670A patent/EP1906964A1/en not_active Withdrawn
- 2006-07-17 US US11/995,929 patent/US20080275027A1/en not_active Abandoned
- 2006-07-17 WO PCT/EP2006/007036 patent/WO2007009741A1/en not_active Ceased
- 2006-07-17 JP JP2008521869A patent/JP2009501745A/ja active Pending