ATE115136T1 - 4-phenylphthalazin-derivate. - Google Patents

4-phenylphthalazin-derivate.

Info

Publication number
ATE115136T1
ATE115136T1 AT91104763T AT91104763T ATE115136T1 AT E115136 T1 ATE115136 T1 AT E115136T1 AT 91104763 T AT91104763 T AT 91104763T AT 91104763 T AT91104763 T AT 91104763T AT E115136 T1 ATE115136 T1 AT E115136T1
Authority
AT
Austria
Prior art keywords
group
carbon atoms
represent
alkyl
integer
Prior art date
Application number
AT91104763T
Other languages
English (en)
Inventor
Norimichi Iwase
Yasuhiro Morinaka
Yoshikuni Tamao
Toshiji Kanayama
Original Assignee
Mitsubishi Chem Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Chem Ind filed Critical Mitsubishi Chem Ind
Application granted granted Critical
Publication of ATE115136T1 publication Critical patent/ATE115136T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT91104763T 1990-03-30 1991-03-26 4-phenylphthalazin-derivate. ATE115136T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8544790 1990-03-30

Publications (1)

Publication Number Publication Date
ATE115136T1 true ATE115136T1 (de) 1994-12-15

Family

ID=13859133

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91104763T ATE115136T1 (de) 1990-03-30 1991-03-26 4-phenylphthalazin-derivate.

Country Status (7)

Country Link
US (1) US5089494A (de)
EP (1) EP0449203B1 (de)
KR (1) KR910016710A (de)
AT (1) ATE115136T1 (de)
CA (1) CA2039258A1 (de)
DE (1) DE69105572T2 (de)
ES (1) ES2068413T3 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW279162B (de) * 1991-09-26 1996-06-21 Mitsubishi Chem Corp
EP0682947B1 (de) 1994-05-19 1997-09-10 Mitsubishi Chemical Corporation Arzneimittel zur therapeutischen und prophylaktischen Behandlung von Krankheiten, die durch Hyperplasie der glatten Muskelzellen bedingt sind
DE69533057T2 (de) 1994-08-09 2005-06-16 Eisai Co., Ltd. Kondensierte pyridazinverbindungen
US5716956A (en) * 1995-06-07 1998-02-10 Bearsden Bearsden Bio, Inc. Dihydrophthalazine antagonists of excitatory amino acid receptors
CA2258079A1 (en) * 1996-08-20 1998-02-26 Mayu Shibazaki Remedy for erection failure comprising fused pyridazine compound
EP0825187A1 (de) * 1996-08-22 1998-02-25 Takeda Chemical Industries, Ltd. Kondensierte Pyridazinylguanidine, ihre Herstellung und Verwendung
ITMI981670A1 (it) * 1998-07-21 2000-01-21 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4
US6689883B1 (en) 1999-09-28 2004-02-10 Bayer Pharmaceuticals Corporation Substituted pyridines and pyridazines with angiogenesis inhibiting activity
US7977333B2 (en) * 2000-04-20 2011-07-12 Bayer Healthcare Llc Substituted pyridines and pyridazines with angiogenesis inhibiting activity
US6903101B1 (en) 2000-08-10 2005-06-07 Bayer Pharmaceuticals Corporation Substituted pyridazines and fused pyridazines with angiogenesis inhibiting activity
JPWO2004089412A1 (ja) * 2003-04-08 2006-07-06 三菱ウェルファーマ株式会社 特異的ｎａｄ（ｐ）ｈオキシダーゼ抑制剤
US11618751B1 (en) 2022-03-25 2023-04-04 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives
US11319319B1 (en) 2021-04-07 2022-05-03 Ventus Therapeutics U.S., Inc. Compounds for inhibiting NLRP3 and uses thereof
WO2023280317A1 (zh) * 2021-07-09 2023-01-12 南京明德新药研发有限公司 苄氨基三并环类化合物及其应用
CN115677702B (zh) * 2021-07-23 2024-07-02 武汉誉祥医药科技有限公司 三并环化合物及其药物组合物和应用
US12331048B2 (en) 2022-10-31 2025-06-17 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
GB1303061A (de) * 1969-05-03 1973-01-17
GB2063249A (en) * 1979-10-09 1981-06-03 Mitsubishi Yuka Pharma 4-Phenylphthalazine derivatives
JPS60218377A (ja) * 1984-04-16 1985-11-01 Mitsubishi Yuka Yakuhin Kk ４−フエニルフタラジン誘導体及びそれを有効成分とする循環改善剤

Also Published As

Publication number Publication date
US5089494A (en) 1992-02-18
DE69105572T2 (de) 1995-05-11
EP0449203B1 (de) 1994-12-07
DE69105572D1 (de) 1995-01-19
KR910016710A (ko) 1991-11-05
ES2068413T3 (es) 1995-04-16
CA2039258A1 (en) 1991-10-01
EP0449203A1 (de) 1991-10-02

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties