DE69105572T2 - 4-Phenylphthalazin-Derivate. - Google Patents

4-Phenylphthalazin-Derivate.

Info

Publication number
DE69105572T2
DE69105572T2 DE69105572T DE69105572T DE69105572T2 DE 69105572 T2 DE69105572 T2 DE 69105572T2 DE 69105572 T DE69105572 T DE 69105572T DE 69105572 T DE69105572 T DE 69105572T DE 69105572 T2 DE69105572 T2 DE 69105572T2
Authority
DE
Germany
Prior art keywords
group
carbon atoms
represent
alkyl
integer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69105572T
Other languages
English (en)
Other versions
DE69105572D1 (de
Inventor
Norimichi Iwase
Yasuhiro Morinaka
Yoshikuni Tamao
Toshiji Kanayama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Application granted granted Critical
Publication of DE69105572D1 publication Critical patent/DE69105572D1/de
Publication of DE69105572T2 publication Critical patent/DE69105572T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69105572T 1990-03-30 1991-03-26 4-Phenylphthalazin-Derivate. Expired - Fee Related DE69105572T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8544790 1990-03-30

Publications (2)

Publication Number Publication Date
DE69105572D1 DE69105572D1 (de) 1995-01-19
DE69105572T2 true DE69105572T2 (de) 1995-05-11

Family

ID=13859133

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69105572T Expired - Fee Related DE69105572T2 (de) 1990-03-30 1991-03-26 4-Phenylphthalazin-Derivate.

Country Status (7)

Country Link
US (1) US5089494A (de)
EP (1) EP0449203B1 (de)
KR (1) KR910016710A (de)
AT (1) ATE115136T1 (de)
CA (1) CA2039258A1 (de)
DE (1) DE69105572T2 (de)
ES (1) ES2068413T3 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW279162B (de) * 1991-09-26 1996-06-21 Mitsubishi Chem Corp
ATE157871T1 (de) 1994-05-19 1997-09-15 Mitsubishi Chem Corp Arzneimittel zur therapeutischen und prophylaktischen behandlung von krankheiten, die durch hyperplasie der glatten muskelzellen bedingt sind
ATE267174T1 (de) 1994-08-09 2004-06-15 Eisai Co Ltd Kondensierte pyridazinverbindungen
US5716956A (en) * 1995-06-07 1998-02-10 Bearsden Bearsden Bio, Inc. Dihydrophthalazine antagonists of excitatory amino acid receptors
CN1121220C (zh) * 1996-08-20 2003-09-17 卫材株式会社 稠合哒嗪系化合物的勃起机能不全症治疗剂
EP0825187A1 (de) * 1996-08-22 1998-02-25 Takeda Chemical Industries, Ltd. Kondensierte Pyridazinylguanidine, ihre Herstellung und Verwendung
ITMI981670A1 (it) * 1998-07-21 2000-01-21 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4
US6689883B1 (en) 1999-09-28 2004-02-10 Bayer Pharmaceuticals Corporation Substituted pyridines and pyridazines with angiogenesis inhibiting activity
US7977333B2 (en) * 2000-04-20 2011-07-12 Bayer Healthcare Llc Substituted pyridines and pyridazines with angiogenesis inhibiting activity
US6903101B1 (en) 2000-08-10 2005-06-07 Bayer Pharmaceuticals Corporation Substituted pyridazines and fused pyridazines with angiogenesis inhibiting activity
JPWO2004089412A1 (ja) * 2003-04-08 2006-07-06 三菱ウェルファーマ株式会社 特異的ｎａｄ（ｐ）ｈオキシダーゼ抑制剤
WO2023280317A1 (zh) * 2021-07-09 2023-01-12 南京明德新药研发有限公司 苄氨基三并环类化合物及其应用
CN115677702A (zh) * 2021-07-23 2023-02-03 武汉誉祥医药科技有限公司 三并环化合物及其药物组合物和应用
US11618751B1 (en) 2022-03-25 2023-04-04 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1303061A (de) * 1969-05-03 1973-01-17
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
GB2063249A (en) * 1979-10-09 1981-06-03 Mitsubishi Yuka Pharma 4-Phenylphthalazine derivatives
JPS60218377A (ja) * 1984-04-16 1985-11-01 Mitsubishi Yuka Yakuhin Kk ４−フエニルフタラジン誘導体及びそれを有効成分とする循環改善剤

Also Published As

Publication number Publication date
EP0449203B1 (de) 1994-12-07
US5089494A (en) 1992-02-18
DE69105572D1 (de) 1995-01-19
ATE115136T1 (de) 1994-12-15
ES2068413T3 (es) 1995-04-16
KR910016710A (ko) 1991-11-05
EP0449203A1 (de) 1991-10-02
CA2039258A1 (en) 1991-10-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee