ATE172463T1 - Pyrrolocarbazol - Google Patents

Pyrrolocarbazol

Info

Publication number
ATE172463T1
ATE172463T1 AT95111472T AT95111472T ATE172463T1 AT E172463 T1 ATE172463 T1 AT E172463T1 AT 95111472 T AT95111472 T AT 95111472T AT 95111472 T AT95111472 T AT 95111472T AT E172463 T1 ATE172463 T1 AT E172463T1
Authority
AT
Austria
Prior art keywords
lower alkyl
pyrrolocarbazole
hydrogen
heteroaryl
chem
Prior art date
Application number
AT95111472T
Other languages
English (en)
Inventor
Chris Allen Broka
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE172463T1 publication Critical patent/ATE172463T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT95111472T 1994-08-04 1995-07-21 Pyrrolocarbazol ATE172463T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28604394A 1994-08-04 1994-08-04

Publications (1)

Publication Number Publication Date
ATE172463T1 true ATE172463T1 (de) 1998-11-15

Family

ID=23096813

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95111472T ATE172463T1 (de) 1994-08-04 1995-07-21 Pyrrolocarbazol

Country Status (29)

Country Link
US (1) US5721267A (de)
EP (1) EP0695755B1 (de)
JP (1) JP2672290B2 (de)
KR (1) KR100326790B1 (de)
CN (1) CN1051551C (de)
AT (1) ATE172463T1 (de)
AU (1) AU692563B2 (de)
BR (1) BR9503536A (de)
CA (1) CA2155148A1 (de)
CO (1) CO4410329A1 (de)
CZ (1) CZ288583B6 (de)
DE (1) DE69505470T2 (de)
DK (1) DK0695755T3 (de)
ES (1) ES2123873T3 (de)
FI (1) FI111258B (de)
HU (1) HU225567B1 (de)
IL (1) IL114785A (de)
MA (1) MA23639A1 (de)
MY (1) MY117092A (de)
NO (1) NO304833B1 (de)
NZ (1) NZ272687A (de)
PE (1) PE34996A1 (de)
PL (1) PL180801B1 (de)
RU (1) RU2162089C2 (de)
SA (1) SA95160203B1 (de)
TR (1) TR199500954A1 (de)
TW (1) TW403652B (de)
UY (1) UY24010A1 (de)
ZA (1) ZA956327B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283203B1 (it) * 1996-03-07 1998-04-16 Ausimont Spa Composizioni estinguenti la fiamma
US6020298A (en) * 1997-03-05 2000-02-01 Ausimont S.P.A. Solvent cleaning agents including additives of the formula Rf -CFX-L containing perfluoroalkylenic units
DE19744257B4 (de) * 1997-10-07 2004-04-15 Zentaris Gmbh Beta-Carboline und deren Verwendung zur Behandlung von malignen und anderen, auf pathologischen Zellproliferationen beruhenden Erkrankungen
US7122679B2 (en) 2000-05-09 2006-10-17 Cephalon, Inc. Multicyclic compounds and the use thereof
JPWO2003051883A1 (ja) * 2001-12-18 2005-04-28 協和醗酵工業株式会社 インドール誘導体
US7094798B1 (en) 2002-04-26 2006-08-22 Pfizer Inc Inhibitors of checkpoint kinases (Wee1 and Chk1)
MXPA04010617A (es) * 2002-04-26 2004-12-13 Warner Lambert Co Inhibidores de quinasa de puntos de control (wee1 y chk1).
JP2012051804A (ja) * 2008-12-26 2012-03-15 Kyoto Univ Eg5阻害剤
RU2404983C1 (ru) * 2009-06-08 2010-11-27 Федеральное Государственное Образовательное Учреждение Высшего Профессионального Образования "Южный Федеральный Университет" СПОСОБ ПОЛУЧЕНИЯ 2-R1-6-R2-5-АРИЛ-ПИРРОЛО[3,4-с]КАРБАЗОЛ-1,3(2Н,6Н)-ДИОНОВ
PL2975024T3 (pl) 2009-06-10 2018-09-28 Chugai Seiyaku Kabushiki Kaisha Związki tetracykliczne
BR112013003879B1 (pt) 2010-08-20 2020-12-22 Chugai Seiyaku Kabushiki Kaisha composição compreendendo compostos tetracíclicos e formulação oralmente administrável que a compreende
TR201815994T4 (tr) 2012-09-25 2018-11-21 Chugai Pharmaceutical Co Ltd Ret inhibitörü.
KR101577098B1 (ko) 2012-11-20 2015-12-14 주식회사 두산 유기 화합물 및 이를 포함하는 유기 전계 발광 소자
CN106458967A (zh) 2014-04-25 2017-02-22 中外制药株式会社 四环化合物的新结晶
CN106456651A (zh) 2014-04-25 2017-02-22 中外制药株式会社 以高用量含有四环性化合物的制剂
TWI718102B (zh) 2014-08-08 2021-02-11 日商中外製藥股份有限公司 4環性化合物的非晶質體
US11077093B2 (en) 2015-01-16 2021-08-03 Chugai Seiyaku Kabushiki Kaisha Combination drug
EP3815688B1 (de) 2018-06-29 2023-12-06 Chugai Seiyaku Kabushiki Kaisha Pharmazeutische zusammensetzung enthaltend ein schwerlösliches basisches medikament
AU2019337018B2 (en) 2018-09-04 2024-03-07 Chugai Seiyaku Kabushiki Kaisha Method of producing tetracyclic compound
KR102509614B1 (ko) * 2022-08-09 2023-03-13 김학수 부직포 패널 제조방법 및 제조장치

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611762D0 (en) * 1986-05-14 1986-06-25 Wellcome Found Polycyclic biocidal compounds
US4785085A (en) * 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs
SK75289A3 (en) * 1988-02-10 1998-05-06 Hoffmann La Roche Substituted pyrroles, their use for producing a drug, and the drug on their base
DE3833008A1 (de) * 1988-09-29 1990-04-05 Goedecke Ag Pyrrolocarbozol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
MC2096A1 (fr) * 1989-02-23 1991-02-15 Hoffmann La Roche Pyrroles substitues
US5166204A (en) * 1989-11-01 1992-11-24 Toyama Chemical Co., Ltd. Isoindole derivatives and salts thereof and antitumor agent comprising the same
DE4005969A1 (de) * 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
AU678435B2 (en) * 1993-05-10 1997-05-29 F. Hoffmann-La Roche Ag Substituted pyrroles
EP0839814A3 (de) * 1993-05-28 1998-09-16 Cephalon, Inc. Indolocarbazolderivate und ihre Verwendung zur Behandlung von Störungen der Vorsteherdrüse

Also Published As

Publication number Publication date
MA23639A1 (fr) 1996-04-01
JP2672290B2 (ja) 1997-11-05
TW403652B (en) 2000-09-01
TR199500954A1 (tr) 1996-10-21
CN1051551C (zh) 2000-04-19
DE69505470T2 (de) 1999-05-12
RU2162089C2 (ru) 2001-01-20
CO4410329A1 (es) 1997-01-09
PL309874A1 (en) 1996-02-05
IL114785A0 (en) 1995-11-27
SA95160203B1 (ar) 2005-07-31
EP0695755B1 (de) 1998-10-21
AU692563B2 (en) 1998-06-11
FI953710L (fi) 1996-02-05
NZ272687A (en) 1997-04-24
PL180801B1 (pl) 2001-04-30
HU225567B1 (en) 2007-03-28
IL114785A (en) 1998-06-15
ZA956327B (en) 1996-02-04
KR100326790B1 (ko) 2002-07-27
BR9503536A (pt) 1996-06-04
PE34996A1 (es) 1996-10-01
US5721267A (en) 1998-02-24
CZ288583B6 (cs) 2001-07-11
HUT73437A (en) 1996-07-29
HK1012341A1 (en) 1999-07-30
JPH0859666A (ja) 1996-03-05
CZ199795A3 (en) 1996-02-14
UY24010A1 (es) 2000-12-29
EP0695755A1 (de) 1996-02-07
CA2155148A1 (en) 1996-02-05
NO953052L (no) 1996-02-05
HU9502270D0 (en) 1995-09-28
CN1123280A (zh) 1996-05-29
AU2722095A (en) 1996-02-15
FI953710A0 (fi) 1995-08-03
FI111258B (fi) 2003-06-30
NO304833B1 (no) 1999-02-22
DK0695755T3 (da) 1999-06-28
MY117092A (en) 2004-05-31
ES2123873T3 (es) 1999-01-16
DE69505470D1 (de) 1998-11-26
KR960007592A (ko) 1996-03-22
NO953052D0 (no) 1995-08-03

Similar Documents

Publication Publication Date Title
ATE172463T1 (de) Pyrrolocarbazol
DK0582788T3 (da) 7-(Substituerede)-9-[(substitueret glycyl)-amido]-demethyl-6-deoxytetracycliner
DK0698606T3 (da) Azolylaminderivat
AU9281198A (en) Benzofuran derivatives
ATE263771T1 (de) Totalsynthese von acylfulvenen mit antitumorwirkung
ATE45354T1 (de) Chinoloncarbonsaeurederivate.
NO944371L (no) Kjemisk forbindelse med blodplateaggregeringsinhibiotoraktivitet
ATE231487T1 (de) 2-phenoxyanilin-derivate
ITMI931012A1 (it) Composti spiro-piranici dotati di caratteristiche fotocromatiche
ATE156486T1 (de) Fungizide 3,4-diaryl-(5h)-furan-2-onederivate
DK0601191T3 (da) Hidtil ukendt tetracyklisk forbindelse
DK0623131T3 (da) Alkylderivater af trazodon med CNS-aktivitet
ATE105565T1 (de) Pradimicinderivate.
EP0421668A3 (en) 1,4-dihydro-4-oxo-3-quinolone derivatives as selectively toxic mammalian antibacterial agents
ES2149180T3 (es) Derivado de pirazolotiazolopirimidina.
ES2077697T3 (es) Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos.
DE60103732D1 (de) Pyrimidinderivate mit antitumor-wirkung

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee