ES2149180T3 - Derivado de pirazolotiazolopirimidina. - Google Patents

Derivado de pirazolotiazolopirimidina.

Info

Publication number
ES2149180T3
ES2149180T3 ES92924885T ES92924885T ES2149180T3 ES 2149180 T3 ES2149180 T3 ES 2149180T3 ES 92924885 T ES92924885 T ES 92924885T ES 92924885 T ES92924885 T ES 92924885T ES 2149180 T3 ES2149180 T3 ES 2149180T3
Authority
ES
Spain
Prior art keywords
represents hydrogen
derivative
pirazolotiazolopirimidina
pyrazolothiazolopyrimidine
immunomodulatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92924885T
Other languages
English (en)
Inventor
Fumio - Fujimidai Suzuki
Yoshisuke Shimotogari Nakasato
Kenji - - Fuyodai Ohmori
Tadafumi - Ooka Tamura
Soichiro - Nakatogari Nag Sato
Hiroshi - - Ishidai Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of ES2149180T3 publication Critical patent/ES2149180T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

SE DESCRIBE UNA PIRAZOLOTIAZOLOPIRIMIDINA DERIVADA REPRESENTADA POR LA FORMULA GENERAL (I) O UNA SAL ACEPTABLE FARMACEUTICAMENTE DE LA MISMA, QUE ES UTIL COMO ANTIINFLAMATORIO, ANALGESICO, INMUNOMODULADOR Y ANTI-ULCEROSO; EN DONDE: R1 REPRESENTA HIDROGENO, ALQUIL INFERIOR (IN) SUBSTITUIDO, ARIL (IN) SUBSTITUIDO, ARALQUIL (IN) SUBSTITUIDO, HALOGENO O NR3R4 EN DONDE R3 Y R4 PUEDEN SER IGUALES O DIFERENTES UNO DE OTRO Y CADA UNO REPRESENTA HIDROGENO, ALQUIL INFERIOR, ARIL O ALCANIL INFERIOR; CUANDO R2 ESTA SUBSTITUIDO EN LA POSICION RESENTA N O CH Y R2 REPRESENTA HIDROGENO, ALQUIL INFERIOR (IN) SUBSTITUIDO, ARIL (IN) SUBSTITUIDO, ARALQUIL (IN) SUBSTITUIDO O ALCOXICARBONIL INFERIOR; MIENTRAS QUE CUANDO R2 ESTA SUBSTITUIDO EN LA POSICION TA TITUIDO, Y R6 Y R7 PUEDEN SER IGUALES O DISTINTOS UNO DEL OTRO Y CADA UNO REPRESENTA HIDROGENO O ALQUIL INFERIOR), ARIL (IN) SUBSTITUIDO, ARALQUIL (IN) SUBSTITUIDO O ALCOXICARBONIL INFERIOR; Y REPRESENTA O O S; Y Q REPRESENTA O - CR8 - CR9 - (CH2)N IGUALES ODIFERENTES UNO DE OTRO Y CADA UNO REPRESENTA HIDROGENO, ALQUIL INFERIOR (IN) SUBSTITUIDO, ARIL (IN) SUBSTITUIDO, ARALQUIL (IN) SUBSTITUIDO O ALCOXICARBONIL INFERIOR, Y N REPRESENTA UN NUMERO ENTERO DESDE 0 A 2.
ES92924885T 1991-12-10 1992-12-07 Derivado de pirazolotiazolopirimidina. Expired - Lifetime ES2149180T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP32617791 1991-12-10
PCT/JP1992/001595 WO1993012120A1 (fr) 1991-12-10 1992-12-07 Derive de pyrazolothiazolopyrimidine

Publications (1)

Publication Number Publication Date
ES2149180T3 true ES2149180T3 (es) 2000-11-01

Family

ID=18184905

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92924885T Expired - Lifetime ES2149180T3 (es) 1991-12-10 1992-12-07 Derivado de pirazolotiazolopirimidina.

Country Status (7)

Country Link
US (1) US5527908A (es)
EP (1) EP0573659B1 (es)
AT (1) ATE194621T1 (es)
CA (1) CA2103678A1 (es)
DE (1) DE69231244T2 (es)
ES (1) ES2149180T3 (es)
WO (1) WO1993012120A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2169732C1 (ru) * 1997-04-02 2001-06-27 Ашкинази Римма Ильинична Производные 5-оксо-5н-[1]-бензопирано-[5,6-b]4-оксо-4н-[1,2]-пиримидо-1,4,5,6-тетрагид ро-1,3-тиазина
IL132137A0 (en) * 1997-04-02 2001-03-19 Natural Drug Sciences Llc Biologically active substance on the basis of tetracyclic nitrogen heterocycles of pyrimidine row
FR2834288B1 (fr) * 2001-12-28 2011-12-16 Virbac Sa Procede de preparation de nouveaux derives n-substitues de 5-amino-phenylpyrazole, nouveaux derives n-substitues de 5-amino-phenylpyrazole et leur utilisation comme agents parasiticides et/ou insecticides

Also Published As

Publication number Publication date
EP0573659A1 (en) 1993-12-15
WO1993012120A1 (fr) 1993-06-24
DE69231244T2 (de) 2001-01-25
CA2103678A1 (en) 1993-06-11
ATE194621T1 (de) 2000-07-15
DE69231244D1 (de) 2000-08-17
US5527908A (en) 1996-06-18
EP0573659B1 (en) 2000-07-12
EP0573659A4 (en) 1994-09-07

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