DE69505470T2 - Pyrrolocarbazol - Google Patents

Pyrrolocarbazol

Info

Publication number
DE69505470T2
DE69505470T2 DE69505470T DE69505470T DE69505470T2 DE 69505470 T2 DE69505470 T2 DE 69505470T2 DE 69505470 T DE69505470 T DE 69505470T DE 69505470 T DE69505470 T DE 69505470T DE 69505470 T2 DE69505470 T2 DE 69505470T2
Authority
DE
Germany
Prior art keywords
lower alkyl
pyrrolocarbazole
hydrogen
heteroaryl
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69505470T
Other languages
English (en)
Other versions
DE69505470D1 (de
Inventor
Chris Allen Broka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE69505470D1 publication Critical patent/DE69505470D1/de
Application granted granted Critical
Publication of DE69505470T2 publication Critical patent/DE69505470T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
DE69505470T 1994-08-04 1995-07-21 Pyrrolocarbazol Expired - Fee Related DE69505470T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28604394A 1994-08-04 1994-08-04

Publications (2)

Publication Number Publication Date
DE69505470D1 DE69505470D1 (de) 1998-11-26
DE69505470T2 true DE69505470T2 (de) 1999-05-12

Family

ID=23096813

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69505470T Expired - Fee Related DE69505470T2 (de) 1994-08-04 1995-07-21 Pyrrolocarbazol

Country Status (30)

Country Link
US (1) US5721267A (de)
EP (1) EP0695755B1 (de)
JP (1) JP2672290B2 (de)
KR (1) KR100326790B1 (de)
CN (1) CN1051551C (de)
AT (1) ATE172463T1 (de)
AU (1) AU692563B2 (de)
BR (1) BR9503536A (de)
CA (1) CA2155148A1 (de)
CO (1) CO4410329A1 (de)
CZ (1) CZ288583B6 (de)
DE (1) DE69505470T2 (de)
DK (1) DK0695755T3 (de)
ES (1) ES2123873T3 (de)
FI (1) FI111258B (de)
HK (1) HK1012341A1 (de)
HU (1) HU225567B1 (de)
IL (1) IL114785A (de)
MA (1) MA23639A1 (de)
MY (1) MY117092A (de)
NO (1) NO304833B1 (de)
NZ (1) NZ272687A (de)
PE (1) PE34996A1 (de)
PL (1) PL180801B1 (de)
RU (1) RU2162089C2 (de)
SA (1) SA95160203B1 (de)
TR (1) TR199500954A1 (de)
TW (1) TW403652B (de)
UY (1) UY24010A1 (de)
ZA (1) ZA956327B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283203B1 (it) * 1996-03-07 1998-04-16 Ausimont Spa Composizioni estinguenti la fiamma
US6020298A (en) * 1997-03-05 2000-02-01 Ausimont S.P.A. Solvent cleaning agents including additives of the formula Rf -CFX-L containing perfluoroalkylenic units
DE19744257B4 (de) * 1997-10-07 2004-04-15 Zentaris Gmbh Beta-Carboline und deren Verwendung zur Behandlung von malignen und anderen, auf pathologischen Zellproliferationen beruhenden Erkrankungen
US7122679B2 (en) * 2000-05-09 2006-10-17 Cephalon, Inc. Multicyclic compounds and the use thereof
EP1464645A1 (de) * 2001-12-18 2004-10-06 Kyowa Hakko Kogyo Co., Ltd. Indolderivat
JP2006504632A (ja) * 2002-04-26 2006-02-09 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー チェックポイントキナーゼ（Ｗｅｅ１およびＣｈｋ１）の阻害剤
US7094798B1 (en) 2002-04-26 2006-08-22 Pfizer Inc Inhibitors of checkpoint kinases (Wee1 and Chk1)
JP2012051804A (ja) * 2008-12-26 2012-03-15 Kyoto Univ Ｅｇ５阻害剤
PL3345903T3 (pl) * 2009-06-10 2020-02-28 Chugai Seiyaku Kabushiki Kaisha Związki tetracykliczne
KR101362589B1 (ko) 2010-08-20 2014-02-12 추가이 세이야쿠 가부시키가이샤 4환성 화합물을 포함하는 조성물
JP5759568B2 (ja) 2012-09-25 2015-08-05 中外製薬株式会社 Ｒｅｔ阻害剤
KR101577098B1 (ko) 2012-11-20 2015-12-14 주식회사 두산 유기 화합물 및 이를 포함하는 유기 전계 발광 소자
RU2016146119A (ru) 2014-04-25 2018-05-29 Чугаи Сейяку Кабусики Кайся Новый кристалл тетрациклического соединения
TWI720943B (zh) 2014-04-25 2021-03-11 日商中外製藥股份有限公司 以高用量含有４環性化合物的製劑
TWI803187B (zh) 2014-08-08 2023-05-21 日商中外製藥股份有限公司 包含４環性化合物的非晶質體之固體分散體及製劑
KR102584344B1 (ko) 2015-01-16 2023-09-27 추가이 세이야쿠 가부시키가이샤 병용 의약
US11939322B2 (en) 2018-09-04 2024-03-26 Chugai Seiyaku Kabushiki Kaisha Method for producing tetracyclic compound
KR102509614B1 (ko) * 2022-08-09 2023-03-13 김학수 부직포 패널 제조방법 및 제조장치

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611762D0 (en) * 1986-05-14 1986-06-25 Wellcome Found Polycyclic biocidal compounds
US4785085A (en) * 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs
SK278989B6 (sk) * 1988-02-10 1998-05-06 F. Hoffmann-La Roche Ag Substituované pyroly, ich použitie na výrobu lieči
DE3833008A1 (de) * 1988-09-29 1990-04-05 Goedecke Ag Pyrrolocarbozol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
MC2096A1 (fr) * 1989-02-23 1991-02-15 Hoffmann La Roche Pyrroles substitues
US5166204A (en) * 1989-11-01 1992-11-24 Toyama Chemical Co., Ltd. Isoindole derivatives and salts thereof and antitumor agent comprising the same
DE4005969A1 (de) * 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
AU678435B2 (en) * 1993-05-10 1997-05-29 F. Hoffmann-La Roche Ag Substituted pyrroles
CA2163904C (en) * 1993-05-28 2000-01-25 Craig A. Dionne Use of indolocarbazole derivatives to treat a pathological condition of the prostate

Also Published As

Publication number Publication date
AU692563B2 (en) 1998-06-11
RU2162089C2 (ru) 2001-01-20
ES2123873T3 (es) 1999-01-16
CN1123280A (zh) 1996-05-29
KR100326790B1 (ko) 2002-07-27
US5721267A (en) 1998-02-24
HU225567B1 (en) 2007-03-28
PL180801B1 (pl) 2001-04-30
IL114785A0 (en) 1995-11-27
CZ199795A3 (en) 1996-02-14
BR9503536A (pt) 1996-06-04
KR960007592A (ko) 1996-03-22
MA23639A1 (fr) 1996-04-01
JPH0859666A (ja) 1996-03-05
AU2722095A (en) 1996-02-15
CN1051551C (zh) 2000-04-19
TW403652B (en) 2000-09-01
SA95160203B1 (ar) 2005-07-31
FI111258B (fi) 2003-06-30
JP2672290B2 (ja) 1997-11-05
ATE172463T1 (de) 1998-11-15
EP0695755B1 (de) 1998-10-21
NO953052D0 (no) 1995-08-03
HU9502270D0 (en) 1995-09-28
HUT73437A (en) 1996-07-29
IL114785A (en) 1998-06-15
NO953052L (no) 1996-02-05
NO304833B1 (no) 1999-02-22
DE69505470D1 (de) 1998-11-26
CA2155148A1 (en) 1996-02-05
UY24010A1 (es) 2000-12-29
CO4410329A1 (es) 1997-01-09
ZA956327B (en) 1996-02-04
HK1012341A1 (en) 1999-07-30
PL309874A1 (en) 1996-02-05
FI953710A (fi) 1996-02-05
FI953710A0 (fi) 1995-08-03
MY117092A (en) 2004-05-31
CZ288583B6 (cs) 2001-07-11
DK0695755T3 (da) 1999-06-28
NZ272687A (en) 1997-04-24
EP0695755A1 (de) 1996-02-07
TR199500954A1 (tr) 1996-10-21
PE34996A1 (es) 1996-10-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee