FI953710A - Uusia pyrrolokarbatsoleja - Google Patents

Uusia pyrrolokarbatsoleja Download PDF

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Publication number
FI953710A
FI953710A FI953710A FI953710A FI953710A FI 953710 A FI953710 A FI 953710A FI 953710 A FI953710 A FI 953710A FI 953710 A FI953710 A FI 953710A FI 953710 A FI953710 A FI 953710A
Authority
FI
Finland
Prior art keywords
pyrrolocarbazoles
new
lower alkyl
hydrogen
heteroaryl
Prior art date
Application number
FI953710A
Other languages
English (en)
Swedish (sv)
Other versions
FI111258B (fi
FI953710A0 (fi
Inventor
Chris Allen Broka
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI953710A0 publication Critical patent/FI953710A0/fi
Publication of FI953710A publication Critical patent/FI953710A/fi
Application granted granted Critical
Publication of FI111258B publication Critical patent/FI111258B/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06Peri-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI953710A 1994-08-04 1995-08-03 1,3-diokso-6-(3-metyyliaminopropyyli)-1,2,3,6-tetrahydro-4-(3-tienyyli)pyrrolo[3,4-c]karbatsoli ja sen suolat sekä näiden käyttö ja farmaseuttinen koostumus FI111258B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28604394A 1994-08-04 1994-08-04
US28604394 1994-08-04

Publications (3)

Publication Number Publication Date
FI953710A0 FI953710A0 (fi) 1995-08-03
FI953710A true FI953710A (fi) 1996-02-05
FI111258B FI111258B (fi) 2003-06-30

Family

ID=23096813

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953710A FI111258B (fi) 1994-08-04 1995-08-03 1,3-diokso-6-(3-metyyliaminopropyyli)-1,2,3,6-tetrahydro-4-(3-tienyyli)pyrrolo[3,4-c]karbatsoli ja sen suolat sekä näiden käyttö ja farmaseuttinen koostumus

Country Status (30)

Country Link
US (1) US5721267A (fi)
EP (1) EP0695755B1 (fi)
JP (1) JP2672290B2 (fi)
KR (1) KR100326790B1 (fi)
CN (1) CN1051551C (fi)
AT (1) ATE172463T1 (fi)
AU (1) AU692563B2 (fi)
BR (1) BR9503536A (fi)
CA (1) CA2155148A1 (fi)
CO (1) CO4410329A1 (fi)
CZ (1) CZ288583B6 (fi)
DE (1) DE69505470T2 (fi)
DK (1) DK0695755T3 (fi)
ES (1) ES2123873T3 (fi)
FI (1) FI111258B (fi)
HK (1) HK1012341A1 (fi)
HU (1) HU225567B1 (fi)
IL (1) IL114785A (fi)
MA (1) MA23639A1 (fi)
MY (1) MY117092A (fi)
NO (1) NO304833B1 (fi)
NZ (1) NZ272687A (fi)
PE (1) PE34996A1 (fi)
PL (1) PL180801B1 (fi)
RU (1) RU2162089C2 (fi)
SA (1) SA95160203B1 (fi)
TR (1) TR199500954A1 (fi)
TW (1) TW403652B (fi)
UY (1) UY24010A1 (fi)
ZA (1) ZA956327B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283203B1 (it) * 1996-03-07 1998-04-16 Ausimont Spa Composizioni estinguenti la fiamma
US6020298A (en) * 1997-03-05 2000-02-01 Ausimont S.P.A. Solvent cleaning agents including additives of the formula Rf -CFX-L containing perfluoroalkylenic units
DE19744257B4 (de) * 1997-10-07 2004-04-15 Zentaris Gmbh Beta-Carboline und deren Verwendung zur Behandlung von malignen und anderen, auf pathologischen Zellproliferationen beruhenden Erkrankungen
US7122679B2 (en) 2000-05-09 2006-10-17 Cephalon, Inc. Multicyclic compounds and the use thereof
EP1464645A1 (en) * 2001-12-18 2004-10-06 Kyowa Hakko Kogyo Co., Ltd. Indole derivative
EP1501831A1 (en) * 2002-04-26 2005-02-02 Warner-Lambert Company Llc Inhibitors of checkpoint kinases (wee1 and chk1)
US7094798B1 (en) 2002-04-26 2006-08-22 Pfizer Inc Inhibitors of checkpoint kinases (Wee1 and Chk1)
JP2012051804A (ja) * 2008-12-26 2012-03-15 Kyoto Univ Eg5阻害剤
LT3345903T (lt) 2009-06-10 2019-12-10 Chugai Pharmaceutical Co Ltd Tetracikliniai junginiai
RU2573392C3 (ru) 2010-08-20 2021-06-24 Чугаи Сейяку Кабусики Кайся Композиция, содержащая тетрациклические соединения
JP5759568B2 (ja) 2012-09-25 2015-08-05 中外製薬株式会社 Ret阻害剤
KR101577098B1 (ko) 2012-11-20 2015-12-14 주식회사 두산 유기 화합물 및 이를 포함하는 유기 전계 발광 소자
KR102478887B1 (ko) 2014-04-25 2022-12-16 추가이 세이야쿠 가부시키가이샤 4환성 화합물을 고용량 함유하는 제제
KR20160142383A (ko) 2014-04-25 2016-12-12 추가이 세이야쿠 가부시키가이샤 4환성 화합물의 신규 결정
TWI718102B (zh) 2014-08-08 2021-02-11 日商中外製藥股份有限公司 4環性化合物的非晶質體
CA2973857C (en) 2015-01-16 2023-11-07 Chugai Seiyaku Kabushiki Kaisha Combination drug
AR116113A1 (es) 2018-09-04 2021-03-31 Chugai Pharmaceutical Co Ltd Método para fabricar un compuesto tetracíclico
KR102509614B1 (ko) * 2022-08-09 2023-03-13 김학수 부직포 패널 제조방법 및 제조장치

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611762D0 (en) * 1986-05-14 1986-06-25 Wellcome Found Polycyclic biocidal compounds
US4785085A (en) * 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs
SK278989B6 (sk) * 1988-02-10 1998-05-06 F. Hoffmann-La Roche Ag Substituované pyroly, ich použitie na výrobu lieči
DE3833008A1 (de) * 1988-09-29 1990-04-05 Goedecke Ag Pyrrolocarbozol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
MC2096A1 (fr) * 1989-02-23 1991-02-15 Hoffmann La Roche Pyrroles substitues
GB2239013B (en) * 1989-11-01 1993-06-02 Toyama Chemical Co Ltd Novel isoindole derivatives and salts thereof,processes for producing the same and antitumor agent comprising the same
DE4005969A1 (de) * 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
AU678435B2 (en) * 1993-05-10 1997-05-29 F. Hoffmann-La Roche Ag Substituted pyrroles
DK0699204T3 (da) * 1993-05-28 1999-02-22 Cephalon Inc Anvendelse af indolocarbazolderivater til behandling af en patologisk tilstand i prostata

Also Published As

Publication number Publication date
ATE172463T1 (de) 1998-11-15
AU692563B2 (en) 1998-06-11
FI111258B (fi) 2003-06-30
UY24010A1 (es) 2000-12-29
JP2672290B2 (ja) 1997-11-05
DE69505470T2 (de) 1999-05-12
HUT73437A (en) 1996-07-29
RU2162089C2 (ru) 2001-01-20
HU225567B1 (en) 2007-03-28
PL309874A1 (en) 1996-02-05
JPH0859666A (ja) 1996-03-05
HU9502270D0 (en) 1995-09-28
PE34996A1 (es) 1996-10-01
DE69505470D1 (de) 1998-11-26
PL180801B1 (pl) 2001-04-30
KR960007592A (ko) 1996-03-22
CZ199795A3 (en) 1996-02-14
BR9503536A (pt) 1996-06-04
NO953052L (no) 1996-02-05
CA2155148A1 (en) 1996-02-05
DK0695755T3 (da) 1999-06-28
NO953052D0 (no) 1995-08-03
EP0695755B1 (en) 1998-10-21
CN1051551C (zh) 2000-04-19
HK1012341A1 (en) 1999-07-30
ES2123873T3 (es) 1999-01-16
ZA956327B (en) 1996-02-04
TW403652B (en) 2000-09-01
CO4410329A1 (es) 1997-01-09
IL114785A0 (en) 1995-11-27
US5721267A (en) 1998-02-24
EP0695755A1 (en) 1996-02-07
IL114785A (en) 1998-06-15
CZ288583B6 (cs) 2001-07-11
CN1123280A (zh) 1996-05-29
MY117092A (en) 2004-05-31
AU2722095A (en) 1996-02-15
NZ272687A (en) 1997-04-24
FI953710A0 (fi) 1995-08-03
MA23639A1 (fr) 1996-04-01
KR100326790B1 (ko) 2002-07-27
NO304833B1 (no) 1999-02-22
TR199500954A1 (tr) 1996-10-21
SA95160203B1 (ar) 2005-07-31

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Legal Events

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MA Patent expired