NO940831L - Diiodforbindelser for anvendelse ved fremstilling av morfolinylderivater av doxorubicin, og deres fremstilling - Google Patents

Diiodforbindelser for anvendelse ved fremstilling av morfolinylderivater av doxorubicin, og deres fremstilling

Info

Publication number
NO940831L
NO940831L NO940831A NO940831A NO940831L NO 940831 L NO940831 L NO 940831L NO 940831 A NO940831 A NO 940831A NO 940831 A NO940831 A NO 940831A NO 940831 L NO940831 L NO 940831L
Authority
NO
Norway
Prior art keywords
preparation
doxorubicin
diode
compounds
morpholinyl derivatives
Prior art date
Application number
NO940831A
Other languages
English (en)
Other versions
NO176911C (no
NO940831D0 (no
NO176911B (no
Inventor
Alberto Bargiotti
Maria Grandi
Antonino Suarato
Daniela Faiardi
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898928654A external-priority patent/GB8928654D0/en
Priority claimed from GB909007513A external-priority patent/GB9007513D0/en
Publication of NO940831L publication Critical patent/NO940831L/no
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Priority to NO940831A priority Critical patent/NO176911C/no
Publication of NO940831D0 publication Critical patent/NO940831D0/no
Publication of NO176911B publication Critical patent/NO176911B/no
Publication of NO176911C publication Critical patent/NO176911C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/313—Compounds having groups containing halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
NO940831A 1989-12-19 1994-03-09 Diiodforbindelser for anvendelse ved fremstilling av morfolinylderivater av doxorubicin, og deres fremstilling NO176911C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO940831A NO176911C (no) 1989-12-19 1994-03-09 Diiodforbindelser for anvendelse ved fremstilling av morfolinylderivater av doxorubicin, og deres fremstilling

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB898928654A GB8928654D0 (en) 1989-12-19 1989-12-19 Preparation of 2-methoxy-4-morpholinyl anthracyclines
GB909007513A GB9007513D0 (en) 1990-04-03 1990-04-03 Morpholinyl derivatives of doxorubicin and process for their preparation
PCT/EP1990/002229 WO1991009046A1 (en) 1989-12-19 1990-12-18 Morpholinyl derivatives of doxorubicin and process for their preparation
NO913176A NO175533C (no) 1989-12-19 1991-08-14 Fremstilling av morfolinylderivater av doxorubicin
NO940831A NO176911C (no) 1989-12-19 1994-03-09 Diiodforbindelser for anvendelse ved fremstilling av morfolinylderivater av doxorubicin, og deres fremstilling

Publications (4)

Publication Number Publication Date
NO940831L true NO940831L (no) 1991-08-14
NO940831D0 NO940831D0 (no) 1994-03-09
NO176911B NO176911B (no) 1995-03-13
NO176911C NO176911C (no) 1995-06-21

Family

ID=26296395

Family Applications (2)

Application Number Title Priority Date Filing Date
NO913176A NO175533C (no) 1989-12-19 1991-08-14 Fremstilling av morfolinylderivater av doxorubicin
NO940831A NO176911C (no) 1989-12-19 1994-03-09 Diiodforbindelser for anvendelse ved fremstilling av morfolinylderivater av doxorubicin, og deres fremstilling

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO913176A NO175533C (no) 1989-12-19 1991-08-14 Fremstilling av morfolinylderivater av doxorubicin

Country Status (28)

Country Link
EP (1) EP0434960B1 (no)
JP (1) JP3300342B2 (no)
KR (1) KR0183033B1 (no)
CN (2) CN1024922C (no)
AT (1) ATE143023T1 (no)
AU (1) AU636429B2 (no)
CA (1) CA2046857C (no)
CZ (1) CZ281949B6 (no)
DE (1) DE69028610T2 (no)
DK (1) DK0434960T3 (no)
ES (1) ES2094136T3 (no)
FI (1) FI97389C (no)
GR (1) GR3021557T3 (no)
HR (1) HRP921226B1 (no)
HU (2) HU208148B (no)
IE (1) IE81174B1 (no)
IL (3) IL111527A (no)
MY (1) MY119192A (no)
NO (2) NO175533C (no)
NZ (1) NZ243695A (no)
PT (1) PT96226B (no)
RU (1) RU2100366C1 (no)
SI (1) SI9012379B (no)
SK (1) SK278994B6 (no)
TW (1) TW208019B (no)
UA (1) UA27108A1 (no)
WO (1) WO1991009046A1 (no)
YU (1) YU48136B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843903A (en) * 1995-11-27 1998-12-01 The Administrators Of The Tulane Educational Fund Targeted cytotoxic anthracycline analogs
ES2274823T3 (es) * 1999-12-29 2007-06-01 Immunogen, Inc. Agentes cototoxicos que comprenden doxorrubicinas y daunorrubicinas y su utilizacion terapeutica.
CN100341589C (zh) 2002-05-24 2007-10-10 血管技术国际股份公司 用于涂覆医用植入物的组合物和方法
JP2006515186A (ja) 2002-09-26 2006-05-25 アンジオテック インターナショナル アクツィエン ゲゼルシャフト 血管周囲ラップ
AU2003300076C1 (en) 2002-12-30 2010-03-04 Angiotech International Ag Drug delivery from rapid gelling polymer composition
MXPA05009849A (es) * 2003-03-18 2005-12-06 Pharmacia Italia Spa Terapia combinada que comprende nemorubicina y un inhibidor de la ciclooxigenasa-2.
CA2658146A1 (en) * 2006-07-12 2008-01-17 Nerviano Medical Sciences S.R.L. Crystalline nemorubicin hydrochloride
EP2277884B1 (en) * 2008-04-11 2017-08-23 Tianjin Hemay Oncology Pharmaceutical Co., Ltd Anthracycline antibiotic derivatives with high activity, preparation methods and uses thereof
CN101353361B (zh) * 2008-08-08 2011-06-01 中国人民解放军第四军医大学 一种阿霉素前体药物的制备方法及其应用
CA2818713C (en) * 2010-12-02 2019-03-26 Nerviano Medical Sciences S.R.L. Process for the preparation of morpholinyl anthracycline derivatives
ES2695162T3 (es) 2013-04-29 2019-01-02 Nerviano Medical Sciences Srl Nuevos derivados de morfolinil antraciclina
EP3084445B1 (en) 2013-12-11 2020-10-28 University of Massachusetts Compositions and methods for treating disease using salmonella t3ss effector protein (sipa)
US20170312290A1 (en) 2014-11-05 2017-11-02 Nerviano Medical Sciences S.R.L. Functionalized morpholinyl anthracycline derivatives
CN115043895A (zh) * 2022-07-15 2022-09-13 戊言医药科技（上海）有限公司 一种pnu-159682及其中间体的制备方法
WO2024038065A1 (en) * 2022-08-15 2024-02-22 Synaffix B.V. Anthracyclins and conjugates thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2883443A (en) * 1956-07-13 1959-04-21 Ruetschi Karl Lead-acid storage battery
US4423123A (en) * 1980-04-17 1983-12-27 Shin-Kobe Electric Machinery Co., Ltd. Electric storage battery and a method of making the same
JPS57163393A (en) * 1981-03-27 1982-10-07 Microbial Chem Res Found Novel anthracyclin derivative and its preparation
US4363857A (en) * 1981-10-16 1982-12-14 General Motors Corporation Laminated metal-plastic battery grid
US4710564A (en) * 1985-01-18 1987-12-01 Microbial Chemistry Research Foundation Anthracycline compounds
GB2172594B (en) * 1985-03-22 1988-06-08 Erba Farmitalia New morpholino derivatives of daunorubicin and doxorubicin
JPS6215323A (ja) * 1986-02-14 1987-01-23 Dainippon Ink & Chem Inc 微多孔中空繊維の製造法
US4861836A (en) * 1986-12-23 1989-08-29 Daikin Industries Ltd. Novel, iodine-containing compound, preparation thereof and block copolymer comprising the same

Also Published As

Publication number Publication date
AU636429B2 (en) 1993-04-29
ES2094136T3 (es) 1997-01-16
IL111527A (en) 1998-02-22
YU237990A (sh) 1993-05-28
IL96643A (en) 1995-01-24
NO175533C (no) 1994-10-26
CZ281949B6 (cs) 1997-04-16
EP0434960A1 (en) 1991-07-03
FI97389B (fi) 1996-08-30
SI9012379B (sl) 2000-02-29
HU209433B (en) 1994-06-28
NO176911C (no) 1995-06-21
JP3300342B2 (ja) 2002-07-08
NO913176L (no) 1991-08-14
HUT60232A (en) 1992-08-28
CN1024922C (zh) 1994-06-08
HRP921226A2 (en) 1995-12-31
JPH04503679A (ja) 1992-07-02
CN1079215A (zh) 1993-12-08
CA2046857A1 (en) 1991-06-20
HRP921226B1 (en) 1998-10-31
CN1039708C (zh) 1998-09-09
GR3021557T3 (en) 1997-02-28
IE81174B1 (en) 2000-06-14
PT96226A (pt) 1991-09-30
DE69028610D1 (de) 1996-10-24
PT96226B (pt) 1998-06-30
SK621990A3 (en) 1998-05-06
TW208019B (no) 1993-06-21
IL111527A0 (en) 1995-01-24
AU6919491A (en) 1991-07-18
HU912994D0 (en) 1992-01-28
KR0183033B1 (ko) 1999-04-01
WO1991009046A1 (en) 1991-06-27
HU208148B (en) 1993-08-30
KR920701228A (ko) 1992-08-11
YU48136B (sh) 1997-05-28
SK278994B6 (sk) 1998-05-06
NO913176D0 (no) 1991-08-14
NO175533B (no) 1994-07-18
HU9200656D0 (en) 1992-05-28
CA2046857C (en) 2001-06-12
CN1053238A (zh) 1991-07-24
FI913887A0 (fi) 1991-08-16
NZ243695A (en) 1993-06-25
CZ621990A3 (en) 1997-01-15
MY119192A (en) 2005-04-30
UA27108A1 (uk) 2000-02-28
FI97389C (fi) 1996-12-10
SI9012379A (en) 1997-12-31
NO940831D0 (no) 1994-03-09
ATE143023T1 (de) 1996-10-15
NO176911B (no) 1995-03-13
DE69028610T2 (de) 1997-02-06
HUT59693A (en) 1992-06-29
EP0434960B1 (en) 1996-09-18
IE904543A1 (en) 1991-06-19
RU2100366C1 (ru) 1997-12-27
IL96643A0 (en) 1991-09-16
DK0434960T3 (da) 1996-10-14

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