NO913176D0 - Morfolinylderivater av doxorubicin og deres fremstilling. - Google Patents

Morfolinylderivater av doxorubicin og deres fremstilling.

Info

Publication number
NO913176D0
NO913176D0 NO913176A NO913176A NO913176D0 NO 913176 D0 NO913176 D0 NO 913176D0 NO 913176 A NO913176 A NO 913176A NO 913176 A NO913176 A NO 913176A NO 913176 D0 NO913176 D0 NO 913176D0
Authority
NO
Norway
Prior art keywords
doxorubicin
preparation
morpholinyl derivatives
morpholinyl
derivatives
Prior art date
Application number
NO913176A
Other languages
English (en)
Other versions
NO913176L (no
NO175533B (no
NO175533C (no
Inventor
Alberto Bargiotti
Maria Grandi
Antonino Suarato
Daniela Faiardi
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898928654A external-priority patent/GB8928654D0/en
Priority claimed from GB909007513A external-priority patent/GB9007513D0/en
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of NO913176L publication Critical patent/NO913176L/no
Publication of NO913176D0 publication Critical patent/NO913176D0/no
Priority to NO940831A priority Critical patent/NO176911C/no
Publication of NO175533B publication Critical patent/NO175533B/no
Publication of NO175533C publication Critical patent/NO175533C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/313—Compounds having groups containing halogen
NO913176A 1989-12-19 1991-08-14 Fremstilling av morfolinylderivater av doxorubicin NO175533C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO940831A NO176911C (no) 1989-12-19 1994-03-09 Diiodforbindelser for anvendelse ved fremstilling av morfolinylderivater av doxorubicin, og deres fremstilling

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898928654A GB8928654D0 (en) 1989-12-19 1989-12-19 Preparation of 2-methoxy-4-morpholinyl anthracyclines
GB909007513A GB9007513D0 (en) 1990-04-03 1990-04-03 Morpholinyl derivatives of doxorubicin and process for their preparation
PCT/EP1990/002229 WO1991009046A1 (en) 1989-12-19 1990-12-18 Morpholinyl derivatives of doxorubicin and process for their preparation

Publications (4)

Publication Number Publication Date
NO913176L NO913176L (no) 1991-08-14
NO913176D0 true NO913176D0 (no) 1991-08-14
NO175533B NO175533B (no) 1994-07-18
NO175533C NO175533C (no) 1994-10-26

Family

ID=26296395

Family Applications (2)

Application Number Title Priority Date Filing Date
NO913176A NO175533C (no) 1989-12-19 1991-08-14 Fremstilling av morfolinylderivater av doxorubicin
NO940831A NO176911C (no) 1989-12-19 1994-03-09 Diiodforbindelser for anvendelse ved fremstilling av morfolinylderivater av doxorubicin, og deres fremstilling

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO940831A NO176911C (no) 1989-12-19 1994-03-09 Diiodforbindelser for anvendelse ved fremstilling av morfolinylderivater av doxorubicin, og deres fremstilling

Country Status (28)

Country Link
EP (1) EP0434960B1 (no)
JP (1) JP3300342B2 (no)
KR (1) KR0183033B1 (no)
CN (2) CN1024922C (no)
AT (1) ATE143023T1 (no)
AU (1) AU636429B2 (no)
CA (1) CA2046857C (no)
CZ (1) CZ281949B6 (no)
DE (1) DE69028610T2 (no)
DK (1) DK0434960T3 (no)
ES (1) ES2094136T3 (no)
FI (1) FI97389C (no)
GR (1) GR3021557T3 (no)
HR (1) HRP921226B1 (no)
HU (2) HU209433B (no)
IE (1) IE81174B1 (no)
IL (3) IL111527A (no)
MY (1) MY119192A (no)
NO (2) NO175533C (no)
NZ (1) NZ243695A (no)
PT (1) PT96226B (no)
RU (1) RU2100366C1 (no)
SI (1) SI9012379B (no)
SK (1) SK278994B6 (no)
TW (1) TW208019B (no)
UA (1) UA27108A1 (no)
WO (1) WO1991009046A1 (no)
YU (1) YU48136B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843903A (en) * 1995-11-27 1998-12-01 The Administrators Of The Tulane Educational Fund Targeted cytotoxic anthracycline analogs
WO2001049698A1 (en) * 1999-12-29 2001-07-12 Immunogen, Inc. Cytotoxic agents comprising modified doxorubicins and daunorubicins and their therapeutic use
PT1509256E (pt) 2002-05-24 2009-10-15 Angiotech Int Ag Composições e métodos de revestimento de implantes médicos
CA2497349C (en) 2002-09-26 2008-07-08 Angiotech International Ag Perivascular wraps
US20040225077A1 (en) 2002-12-30 2004-11-11 Angiotech International Ag Drug delivery from rapid gelling polymer composition
CA2519310A1 (en) * 2003-03-18 2004-09-30 Maria Adele Pacciarini Combined therapy comprising nemorubicin and a cyclooxygenase-2-inhibitor
EA200970116A1 (ru) * 2006-07-12 2009-08-28 НЕРВИАНО МЕДИКАЛ САЙЕНСИЗ С.р.л. Кристаллический гидрохлорид неморубицина
CA2721140C (en) * 2008-04-11 2016-02-09 Tianjin Hemay Bio-Tech Co. Ltd. Tetracyclic anthraquinone antibiotic derivatives with high activity, process for preparing the same and use thereof
CN101353361B (zh) * 2008-08-08 2011-06-01 中国人民解放军第四军医大学 一种阿霉素前体药物的制备方法及其应用
MX2013005972A (es) * 2010-12-02 2013-08-09 Nerviano Medical Sciences Srl Proceso para la preparacion de derivados de morfolinil antraciclina.
EP2991993B1 (en) 2013-04-29 2018-06-06 Nerviano Medical Sciences S.r.l. Morpholinyl anthracycline derivatives
WO2015089268A1 (en) 2013-12-11 2015-06-18 University Of Massachusetts Compositions and methods for treating disease using salmonella t3ss effector protein (sipa)
EP3215513B1 (en) 2014-11-05 2019-05-08 Nerviano Medical Sciences S.r.l. Functionalized morpholinyl anthracycline derivatives
CN115043895A (zh) * 2022-07-15 2022-09-13 戊言医药科技（上海）有限公司 一种pnu-159682及其中间体的制备方法
WO2024038065A1 (en) * 2022-08-15 2024-02-22 Synaffix B.V. Anthracyclins and conjugates thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2883443A (en) * 1956-07-13 1959-04-21 Ruetschi Karl Lead-acid storage battery
US4423123A (en) * 1980-04-17 1983-12-27 Shin-Kobe Electric Machinery Co., Ltd. Electric storage battery and a method of making the same
JPS57163393A (en) * 1981-03-27 1982-10-07 Microbial Chem Res Found Novel anthracyclin derivative and its preparation
US4363857A (en) * 1981-10-16 1982-12-14 General Motors Corporation Laminated metal-plastic battery grid
US4710564A (en) * 1985-01-18 1987-12-01 Microbial Chemistry Research Foundation Anthracycline compounds
GB2172594B (en) * 1985-03-22 1988-06-08 Erba Farmitalia New morpholino derivatives of daunorubicin and doxorubicin
JPS6215323A (ja) * 1986-02-14 1987-01-23 Dainippon Ink & Chem Inc 微多孔中空繊維の製造法
US4861836A (en) * 1986-12-23 1989-08-29 Daikin Industries Ltd. Novel, iodine-containing compound, preparation thereof and block copolymer comprising the same

Also Published As

Publication number Publication date
MY119192A (en) 2005-04-30
SK621990A3 (en) 1998-05-06
NO176911B (no) 1995-03-13
NO176911C (no) 1995-06-21
HRP921226B1 (en) 1998-10-31
EP0434960B1 (en) 1996-09-18
HU209433B (en) 1994-06-28
TW208019B (no) 1993-06-21
HUT60232A (en) 1992-08-28
NO913176L (no) 1991-08-14
NO175533B (no) 1994-07-18
ES2094136T3 (es) 1997-01-16
CZ621990A3 (en) 1997-01-15
CA2046857A1 (en) 1991-06-20
IL111527A0 (en) 1995-01-24
WO1991009046A1 (en) 1991-06-27
SI9012379B (sl) 2000-02-29
HUT59693A (en) 1992-06-29
SI9012379A (en) 1997-12-31
YU48136B (sh) 1997-05-28
AU636429B2 (en) 1993-04-29
YU237990A (sh) 1993-05-28
RU2100366C1 (ru) 1997-12-27
IE81174B1 (en) 2000-06-14
FI97389C (fi) 1996-12-10
PT96226A (pt) 1991-09-30
NO940831L (no) 1991-08-14
CN1053238A (zh) 1991-07-24
CN1024922C (zh) 1994-06-08
DE69028610T2 (de) 1997-02-06
HRP921226A2 (en) 1995-12-31
JP3300342B2 (ja) 2002-07-08
AU6919491A (en) 1991-07-18
KR920701228A (ko) 1992-08-11
HU208148B (en) 1993-08-30
FI913887A0 (fi) 1991-08-16
ATE143023T1 (de) 1996-10-15
DK0434960T3 (da) 1996-10-14
KR0183033B1 (ko) 1999-04-01
IL111527A (en) 1998-02-22
JPH04503679A (ja) 1992-07-02
NZ243695A (en) 1993-06-25
IL96643A0 (en) 1991-09-16
CA2046857C (en) 2001-06-12
EP0434960A1 (en) 1991-07-03
HU9200656D0 (en) 1992-05-28
GR3021557T3 (en) 1997-02-28
DE69028610D1 (de) 1996-10-24
CN1039708C (zh) 1998-09-09
FI97389B (fi) 1996-08-30
CN1079215A (zh) 1993-12-08
UA27108A1 (uk) 2000-02-28
HU912994D0 (en) 1992-01-28
IE904543A1 (en) 1991-06-19
PT96226B (pt) 1998-06-30
CZ281949B6 (cs) 1997-04-16
SK278994B6 (sk) 1998-05-06
NO940831D0 (no) 1994-03-09
NO175533C (no) 1994-10-26
IL96643A (en) 1995-01-24

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