|
US2809194A
(en)
|
|
1957-10-08 |
|
Thiadiazine type natriuretic agents |
|
US115905A
(en)
|
|
1871-06-13 |
|
Improvement in trunks |
|
US3962A
(en)
|
|
1845-03-21 |
|
Fowler m |
|
US2976289A
(en)
|
|
1961-03-21 |
|
X-tetrahydro - |
|
US3108097A
(en)
|
|
1963-10-22 |
|
Ehnojs |
|
US2937169A
(en)
|
|
1960-05-17 |
|
Toiutf alrtqn of h |
|
US3562A
(en)
|
|
1844-04-25 |
|
Improvement in seed-planters |
|
US3935A
(en)
|
|
1845-02-28 |
|
Improvement in machines for cutting sausage-meat |
|
US2661372A
(en)
|
|
1953-12-01 |
|
Pharmacologically valuable stereo |
|
US2882271A
(en)
|
|
1959-04-14 |
|
Xcixcxh |
|
US3254076A
(en)
|
|
1966-05-31 |
|
Sulfamyl
hydro |
|
US30577A
(en)
|
|
1860-11-06 |
|
Truss-bridge |
|
US3009911A
(en)
|
|
1961-11-21 |
|
Derivatives of j |
|
US267A
(en)
|
|
1837-07-11 |
|
Mcode of hanging ob suspending a band-wheel in those hobse-powebs in |
|
US3262852A
(en)
|
|
1966-07-26 |
|
Vasodilator and anti-anginose com-
pounds containing methoxy benzyl
piperazines and method of using the
same |
|
US238A
(en)
|
|
1837-06-15 |
|
Capstan |
|
US2783241A
(en)
|
|
1957-02-26 |
|
S-acylimino-x-substituted-az-i |
|
SE168308C1
(https=)
|
|
|
|
|
|
US3164588A
(en)
|
|
1965-01-05 |
|
Hjnsoj |
|
US2161938A
(en)
|
1934-07-31 |
1939-06-13 |
Soc Of Chemical Ind |
Imidazolines
|
|
US2357985A
(en)
|
1940-07-30 |
1944-09-12 |
Research Corp |
Synthesis of hexoestrol
|
|
DE905738C
(de)
|
1943-06-11 |
1954-11-02 |
Diwag Chemische Fabriken Ag |
Verfahren zur Herstellung basischer Thymoldimethylaminoaethylaether
|
|
US2500444A
(en)
|
1944-10-10 |
1950-03-14 |
Polaroid Corp |
Uramidohomomeroquinene
|
|
AT168063B
(de)
|
1948-11-23 |
1951-04-10 |
Richter Gedeon Vegyeszet |
Verfahren zur Herstellung von neuen asymmetrischen Substitutionsprodukten des 2,4-Diamino-1,3,5-Triazins
|
|
DE860217C
(de)
|
1950-10-28 |
1952-12-18 |
Albert Ag Chem Werke |
Verfahren zur Herstellung von 1-Hexyl-3, 7-dimethylxanthin
|
|
GB740932A
(en)
|
1952-08-01 |
1955-11-23 |
Rhone Poulenc Sa |
Improvements in or relating to phenthiazine derivatives
|
|
US2661373A
(en)
|
1953-03-02 |
1953-12-01 |
Kulz Ida |
Certain amino alcohols and ketones
|
|
US2816118A
(en)
|
1953-11-12 |
1957-12-10 |
S B Penick & Company Inc |
Isolation of crystalline components from visnagan
|
|
FR1103113A
(fr)
|
1954-04-15 |
1955-10-31 |
|
Triméthylol-alcanes et leur procédé de préparation
|
|
GB769757A
(en)
|
1954-05-13 |
1957-03-13 |
American Cyanamid Co |
Improvements in or relating to the manufacture of sulfonamides
|
|
US2769015A
(en)
|
1954-10-06 |
1956-10-30 |
Lab Laroche Navarron |
Process of preparing 3-methyl-chromone
|
|
GB795174A
(en)
|
1954-10-13 |
1958-05-21 |
Upjohn Co |
Heterocyclic sulphonamides
|
|
GB807826A
(en)
|
1955-03-14 |
1959-01-21 |
Thomae Gmbh Dr K |
Derivatives of pyrimido[5,4-d] pyrimidine and production thereof
|
|
FR1165845A
(fr)
|
1955-05-28 |
1958-10-29 |
Philips Nv |
Amines secondaires portant des substituants et leur préparation
|
|
GB803372A
(en)
|
1955-11-02 |
1958-10-22 |
Recordati Lab Farmacologico S |
Hydroxychromone derivatives and methods of preparing the same
|
|
US3012042A
(en)
|
1956-12-21 |
1961-12-05 |
Belge Produits Chimiques Sa |
Benzofurans
|
|
NL224562A
(https=)
|
1957-02-05 |
|
|
|
|
US2980679A
(en)
|
1957-04-04 |
1961-04-18 |
Omikron Gagliardi Societa Di F |
Process for preparing heterocyclic sulfonamides
|
|
GB824547A
(en)
|
1957-05-07 |
1959-12-02 |
Recordati Lab Farmacologico S |
Process for preparing flavone-7-ethyl oxyacetate
|
|
US3055904A
(en)
|
1957-11-04 |
1962-09-25 |
Geigy Chem Corp |
New isoindoline derivatives
|
|
US2965656A
(en)
|
1957-11-07 |
1960-12-20 |
Merck & Co Inc |
Process for preparing substituted 1-amino-2, 4-benzene-disulfonamides
|
|
US2965655A
(en)
|
1957-11-07 |
1960-12-20 |
Merck & Co Inc |
Process for preparing substituted 1-amino 2, 4-benzene-disulfonamides
|
|
US2980699A
(en)
|
1957-12-20 |
1961-04-18 |
S B Penick And Company |
Dihydropyranocoumarin derivatives and process for their production
|
|
FR1217929A
(fr)
|
1958-03-03 |
1960-05-06 |
Ciba Geigy |
Procédé de préparation du 1,1-dioxyde de la 6-chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine et de ses sels
|
|
CH366523A
(de)
|
1958-04-14 |
1963-01-15 |
Eprova Ag |
Verfahren zur Herstellung der neuen 1,3,4,6- und 1,3,4,5-Tetranicotinoyl-fructose
|
|
BE578515A
(https=)
|
1958-05-07 |
|
|
|
|
GB851287A
(en)
|
1958-07-10 |
1960-10-12 |
British Drug Houses Ltd |
5-chlorotoluene-2:4-disulphonamide and alkali metal salts thereof
|
|
DE1102750B
(de)
|
1958-07-17 |
1961-03-23 |
Wuelfing J A Fa |
Verfahren zur Herstellung eines Salzes von Theophyllinbasen
|
|
GB856409A
(en)
|
1958-07-26 |
1960-12-14 |
Chime Et Atomistique |
Improvements in and relating to a new pyridazine derivative and its process of preparation
|
|
GB862248A
(en)
|
1958-08-04 |
1961-03-08 |
Italseber S P A |
Di-isopropylammonium salts of chloroacetic and chloropropionic acids
|
|
US2970082A
(en)
|
1958-10-07 |
1961-01-31 |
Walker Lab Inc |
Aluminum nicotinate compositions for hypercholesteremia
|
|
GB885078A
(en)
|
1959-01-12 |
1961-12-20 |
Ciba Ltd |
3:4-dihydro-1:2:4-benzothiadiazine-1:1-dioxides and process for their manufacture
|
|
ES255386A1
(es)
|
1959-02-04 |
1960-09-16 |
Ciba Geigy |
Procedimiento para preparar derivados del 3,4-dihidro-1,2,4-benzotiadiazina-1,1,-diëxido
|
|
US3058882A
(en)
|
1959-12-28 |
1962-10-16 |
Hoechst Ag |
N'-substituted-3-carboxy-6-halo-sulfanilamide and derivatives thereof
|
|
DE1102973B
(de)
|
1960-03-25 |
1961-03-23 |
Bayer Ag |
Verfahren zur Herstellung von hoch gereinigten Kallikrein-Praeparaten
|
|
NL291944A
(https=)
|
1960-05-04 |
|
|
|
|
DE1265758B
(de)
|
1960-05-25 |
1968-04-11 |
Guidotti & C Spa Labor |
Verfahren zur Herstellung von o-(beta-Dialkylaminoaethoxy)-phenylketonen und deren Saeureadditionssalzen und quartaeren Salzen
|
|
US3081230A
(en)
|
1960-09-08 |
1963-03-12 |
Smith Kline French Lab |
Diuretic and antihypertensive triaminoarylpteridines
|
|
DE1302648B
(https=)
|
1960-09-27 |
|
|
|
|
SE300218B
(https=)
|
1960-11-08 |
1968-04-22 |
Recip Ab |
|
|
NL270803A
(https=)
|
1960-11-09 |
|
|
|
|
US3255241A
(en)
|
1961-01-19 |
1966-06-07 |
Merck & Co Inc |
(2-alkylidene acyl)phenoxy-and (2-alkylidene acyl)phenylmercaptocarboxylic acids
|
|
US3072653A
(en)
|
1961-03-06 |
1963-01-08 |
Warner Lamber Pharmaceutical C |
5-amino derivatives of 4-thiazolidinones and process therefor
|
|
DE1154810B
(de)
|
1961-04-01 |
1963-09-26 |
Knoll Ag |
Verfahren zur Herstellung basisch substituierter Phenylacetonitrile
|
|
FR1312427A
(fr)
|
1961-04-12 |
1962-12-21 |
Science Union Et Compagnie Soc |
Nouveaux dérivés de la pipérazine et leurs préparations
|
|
GB979994A
(en)
|
1961-07-28 |
1965-01-06 |
May & Baker Ltd |
Isoindolinone derivatives
|
|
NL281593A
(https=)
|
1961-07-31 |
|
|
|
|
US3160641A
(en)
|
1961-08-07 |
1964-12-08 |
Atlas Chem Ind |
Purification of isosorbide
|
|
NL281975A
(https=)
|
1961-08-12 |
|
|
|
|
GB984810A
(en)
|
1961-10-05 |
1965-03-03 |
Farmaceutici Italia |
Polypeptides
|
|
DE1236523C2
(de)
|
1962-02-15 |
1975-06-12 |
Sanol-Arzneimittel Dr. Schwarz Gmbh, 4019 Monheim |
Verfahren zur herstellung von basischen phenylaethern und deren salzen
|
|
US3262977A
(en)
|
1962-03-10 |
1966-07-26 |
Chinoin Gyogyszer Es Vegyeszet |
N-aralkyl-1, 1-diphenyl-propylamine derivatives
|
|
BE629910A
(https=)
|
1962-03-22 |
|
|
|
|
US3188329A
(en)
|
1962-04-10 |
1965-06-08 |
Colgate Palmolive Co |
Diuretic anils
|
|
US3228943A
(en)
|
1962-06-11 |
1966-01-11 |
|
Lumilysergol derivatives |
|
US3338899A
(en)
|
1962-07-09 |
1967-08-29 |
Aron Samuel |
3-phenyl-5-amino-1, 2, 4-oxadiazole compounds
|
|
US3265573A
(en)
|
1962-07-27 |
1966-08-09 |
Squibb & Sons Inc |
Benzothiadiazinesulfonamide-1, 1-dioxide composition
|
|
BE639386A
(https=)
|
1962-10-30 |
|
|
|
|
NL300886A
(https=)
|
1962-11-23 |
|
|
|
|
NL301580A
(https=)
|
1962-12-11 |
|
|
|
|
NL142872C
(https=)
|
1963-03-28 |
|
|
|
|
FR2790M
(fr)
|
1963-05-24 |
1964-10-16 |
Soc Ind Fab Antibiotiques Sifa |
Nouveaux dérivés des thiachromanes.
|
|
FR1365504A
(fr)
|
1963-05-24 |
1964-07-03 |
Soc Ind Fab Antibiotiques Sifa |
Nouveaux dérivés des thiachromanes et procédé de préparation
|
|
GB1069343A
(en)
|
1963-09-10 |
1967-05-17 |
Ici Ltd |
Propanolamine derivatives
|
|
US3238215A
(en)
|
1963-10-17 |
1966-03-01 |
Sterling Drug Inc |
1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines
|
|
NL127996C
(https=)
|
1963-11-19 |
|
|
|
|
BR6464291D0
(pt)
|
1963-11-26 |
1973-07-26 |
Merrell Inc Richardson |
Processo para preparar o novo composto quimico 1-1-di cloro-hexil-2-(2-piperidil)-etina
|
|
DE1278443C2
(de)
|
1963-11-30 |
1975-07-24 |
Bayer Ag, 5090 Leverkusen |
Verfahren zur herstellung von 2,4-disulfonamid-1-chlorbenzolen
|
|
NL128190C
(https=)
|
1964-02-07 |
|
|
|
|
FR1390056A
(fr)
|
1964-04-21 |
1965-02-19 |
Holding Ceresia S A |
Procédé de préparation de nouveaux dérivés du tétrahydronaphtalène et produits conformes à ceux obtenus par le présent procédé ou procédé similaire
|
|
NL127065C
(https=)
|
1964-04-22 |
|
|
|
|
NL137318C
(https=)
|
1964-06-09 |
|
|
|
|
US3422107A
(en)
|
1964-09-05 |
1969-01-14 |
Albert Ag Chem Werke |
Certain oxoalkyldimethylxanthines and a process for the preparation thereof
|
|
NL130749C
(https=)
|
1964-09-10 |
|
|
|
|
GB1078852A
(en)
|
1964-09-30 |
1967-08-09 |
Ici Ltd |
Alkanolamine derivatives
|
|
NL6514807A
(https=)
|
1964-11-18 |
1966-05-20 |
|
|
|
GB1084150A
(https=)
|
1965-01-12 |
|
|
|
|
US3929836A
(en)
|
1965-05-11 |
1975-12-30 |
Hoffmann La Roche |
2-(2-Lower alkylamino-1-hydroxy-ethyl)-substituted benzofurans
|
|
FR1460571A
(fr)
|
1965-06-10 |
1966-03-04 |
Innothera Lab Sa |
Composés thiényl acétiques et leur préparation
|
|
DE1270544B
(de)
|
1965-06-19 |
1968-06-20 |
Beiersdorf Ag |
4-Chlor-5-sulfamylsalicylsaeure-(2', 6'-dimethyl)-anilid und dessen Alkali- oder Ammonium-Salze sowie Verfahren zu deren Herstellung
|
|
DE1545575C2
(de)
|
1965-12-16 |
1970-09-10 |
Asta-Werke Ag, Chemische Fabrik, 4812 Brackwede |
N, N'-Bis- eckige Klammer auf 3"(3', 4', 5'-trimethoxybenzoyloxy)-propyl eckige Klammer zu -homopiperazin
|
|
US3360518A
(en)
|
1966-01-03 |
1967-12-26 |
Wallace & Tiernan Inc |
Tetrahydro-halo-sulfamyl quinazolinones
|
|
CH472404A
(de)
|
1966-03-04 |
1969-05-15 |
Sandoz Ag |
Verfahren zur Herstellung neuer Indolderivate
|
|
CH469002A
(de)
|
1966-06-21 |
1969-02-28 |
Sandoz Ag |
Verfahren zur Herstellung neuer Indolderivate
|
|
FR5733M
(https=)
|
1966-09-27 |
1968-01-22 |
|
|
|
FR6087M
(https=)
|
1967-01-10 |
1968-06-04 |
|
|
|
US3961071A
(en)
|
1967-02-06 |
1976-06-01 |
Boehringer Ingelheim Gmbh |
Therapeutic compositions and method
|
|
US3940489A
(en)
|
1967-02-06 |
1976-02-24 |
Boehringer Ingelheim Gmbh |
Therapeutic compositions and method
|
|
GB1160925A
(en)
|
1967-02-08 |
1969-08-06 |
Menarini Sas |
2-Substituted Benzofuran Derivatives
|
|
DE1668055B2
(de)
|
1967-03-10 |
1973-09-06 |
Farbwerke Hoechst AG, vormals Mei ster Lucius & Bruning, 6000 Frankfurt |
Basisch substituierte cyclopentylphenolaether, deren salze mit physiologisch vertraeglichen saeuren und verfahren zu deren herstellung
|
|
DE1670827C3
(de)
|
1967-03-20 |
1974-10-24 |
Bayer Ag, 5090 Leverkusen |
4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin
|
|
US3563997A
(en)
|
1967-12-04 |
1971-02-16 |
Yoshitomi Pharmaceutical |
Certain thieno(2,3-c)pyridines
|
|
US3511836A
(en)
|
1967-12-13 |
1970-05-12 |
Pfizer & Co C |
2,4,6,7-tetra substituted quinazolines
|
|
US3857952A
(en)
|
1967-12-22 |
1974-12-31 |
May & Baker Ltd |
Certain benzene derivatives useful in treating cardiac disorders
|
|
BE729170A
(https=)
|
1968-03-02 |
1969-08-01 |
|
|
|
GB1203691A
(en)
|
1968-03-06 |
1970-09-03 |
Science Union & Cie |
New disubstituted n-amino indoline derivatives and process for preparing them
|
|
GB1218591A
(en)
|
1968-04-03 |
1971-01-06 |
Delalande Sa |
Derivatives of n-(3,4,5-trimethoxy cennamoyl) piperazine and their process of preparation
|
|
US4045482A
(en)
|
1968-11-12 |
1977-08-30 |
Yamanouchi Pharmaceutical Co. Ltd. |
4-(3-Isopropylamino-2-hydroxypropoxy indene
|
|
DE1815922C3
(de)
|
1968-12-20 |
1979-04-26 |
Boehringer Mannheim Gmbh, 6800 Mannheim |
5-Phenyltetrazol-Derivate
|
|
FR8120M
(https=)
|
1968-12-26 |
1970-08-03 |
|
|
|
US3836671A
(en)
|
1969-02-21 |
1974-09-17 |
Ici Ltd |
Alkanolamine derivatives for producing beta-adrenergic blockade
|
|
GB1285038A
(en)
|
1969-02-21 |
1972-08-09 |
Ici Ltd |
Alkanolamine derivatives
|
|
US3655663A
(en)
|
1969-04-21 |
1972-04-11 |
Burton K Wasson |
4-(3-secondary amino-2-hydroxy-proxy) 1 2 5-thiadiazoles
|
|
US3663570A
(en)
|
1969-04-28 |
1972-05-16 |
Sankyo Co |
Coumarin derivatives
|
|
GB1262785A
(en)
|
1969-04-29 |
1972-02-09 |
Orsymonde |
Improvements in or relating to phloroglucinol derivatives
|
|
CA956632A
(en)
|
1969-05-16 |
1974-10-22 |
Yoshitomi Pharmaceutical Industries |
Phenoxy-aminopropanol derivatives
|
|
US4012444A
(en)
|
1969-07-08 |
1977-03-15 |
Allen & Hanburys Limited |
5-[1-Hydroxy-2-(1-methyl-3-phenylpropyl)aminoethyl] salicylamide and physiologically acceptable acid addition salts thereof
|
|
US3634583A
(en)
|
1969-07-24 |
1972-01-11 |
Leo Pharm Prod Ltd |
Pharmaceutical composition for the treatment of oedematous conditions and hypertension
|
|
BE757001A
(fr)
|
1969-10-10 |
1971-03-16 |
Cerpha |
Derives heterocycliques d'acides phenoxy acetique et leur preparation
|
|
US4018824A
(en)
|
1969-11-28 |
1977-04-19 |
Teikoku Hormone Mfg. Co., Ltd. |
1-Aryloxy-3-aminopropane derivatives
|
|
US3935259A
(en)
|
1970-01-08 |
1976-01-27 |
Ciba-Geigy Corporation |
New amines and processes for their manufacture
|
|
US4038313A
(en)
|
1970-01-08 |
1977-07-26 |
Ciba-Geigy Corporation |
Cycloalkylureido phenoxy propanolamines
|
|
SE354851B
(https=)
|
1970-02-18 |
1973-03-26 |
Haessle Ab |
|
|
US3770724A
(en)
|
1970-03-31 |
1973-11-06 |
Roussel Uclaf |
Process for preparing pentacyclic alkaloids
|
|
GB1308191A
(en)
|
1970-04-06 |
1973-02-21 |
Science Union & Cie |
Thiochroman derivatives and a process for preparing them
|
|
US3663597A
(en)
|
1970-05-05 |
1972-05-16 |
American Home Prod |
Process for the purification of cyclandelate
|
|
FR2092133B1
(https=)
|
1970-05-06 |
1974-03-22 |
Orsymonde |
|
|
US3669968A
(en)
|
1970-05-21 |
1972-06-13 |
Pfizer |
Trialkoxy quinazolines
|
|
US4059622A
(en)
|
1970-05-27 |
1977-11-22 |
Imperial Chemical Industries Limited |
Alkanolamine derivatives
|
|
FR2092895B1
(https=)
|
1970-06-29 |
1973-07-13 |
Lafon Victor |
|
|
DE2117571C3
(de)
|
1971-04-10 |
1979-10-11 |
Bayer Ag, 5090 Leverkusen |
Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
|
|
CA989411A
(en)
|
1971-05-13 |
1976-05-18 |
Kakenyaku Kako Co. |
Benzofuran derivatives and preparation thereof
|
|
DE2815926A1
(de)
|
1978-04-13 |
1979-10-18 |
Boehringer Mannheim Gmbh |
Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
|
|
US3773939A
(en)
|
1971-11-24 |
1973-11-20 |
Janssen Pharmaceutica Nv |
N-arallyl-n'-aralkyl piperazine pharmaceutical compositions
|
|
JPS5229318B2
(https=)
|
1972-03-30 |
1977-08-01 |
|
|
|
US3910924A
(en)
|
1972-04-13 |
1975-10-07 |
Otsuka Pharma Co Ltd |
3,4-Dihydrocarbostyril derivatives and a process for preparing the same
|
|
ZA732937B
(en)
|
1972-05-05 |
1974-03-27 |
Maggioni & C Spa |
Non mercurial diuretics
|
|
GB1435139A
(en)
|
1972-08-17 |
1976-05-12 |
Sumitomo Chemical Co |
Thiazole derivatives
|
|
US3985758A
(en)
|
1973-02-20 |
1976-10-12 |
Yamanouchi Pharmaceutical Co., Ltd. |
1,4-Dihydropyridine derivatives
|
|
GB1390748A
(en)
|
1973-04-09 |
1975-04-16 |
Continental Pharma |
Alkyl and cycloalkylthiophenylalkylaminoalkanols their salts and the preparation thereof
|
|
DE2319278C2
(de)
|
1973-04-17 |
1986-02-20 |
Bayer Ag, 5090 Leverkusen |
Pharmazeutisches Mittel
|
|
US3857981A
(en)
|
1973-06-20 |
1974-12-31 |
Armour & Co |
Preserving red color in red meats
|
|
US4062950A
(en)
|
1973-09-22 |
1977-12-13 |
Bayer Aktiengesellschaft |
Amino sugar derivatives
|
|
US4146643A
(en)
|
1973-12-18 |
1979-03-27 |
Sandoz Ltd. |
Increasing vigilance or treating cerebral insufficiency with substituted vincamines
|
|
AT334385B
(de)
|
1973-12-20 |
1976-01-10 |
Chemie Linz Ag |
Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen
|
|
NL175059C
(nl)
|
1974-02-23 |
|
Boehringer Mannheim Gmbh |
Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten.
|
|
GB1501632A
(en)
|
1974-06-28 |
1978-02-22 |
Cm Ind |
Aromatic ketones having cardiovascular activity
|
|
GB1477664A
(en)
|
1974-04-17 |
1977-06-22 |
Christiaens Sa A |
Pyridine derivatives
|
|
DE2419970C3
(de)
|
1974-04-25 |
1980-06-12 |
Hoechst Ag, 6000 Frankfurt |
3-<l-Pyrrolidinyl)-4-phenoxy-5sulfamoylbenzoesäure und Verfahren zu ihrer Herstellung
|
|
DE2521113A1
(de)
|
1974-05-15 |
1976-03-18 |
Maggioni & C Spa |
Cycloaliphatische derivate von 3.3-diphenylpropylamin
|
|
JPS5612114B2
(https=)
|
1974-06-07 |
1981-03-18 |
|
|
|
US4338322A
(en)
|
1975-07-02 |
1982-07-06 |
Fujisawa Pharmaceutical Co., Ltd. |
1,4-Dihydropyridine derivatives, pharmaceutical compositions containing same and methods of effecting vasodilation using same
|
|
US4129565A
(en)
|
1975-07-11 |
1978-12-12 |
Nisshin Flour Milling Co., Ltd. |
Isocarbostyril derivatives
|
|
US4340541A
(en)
|
1975-08-15 |
1982-07-20 |
Sandoz Ltd. |
4-(2-Benzoyloxy-3-tert.-butylaminopropoxy-2-methyl indole
|
|
US4035750A
(en)
|
1975-10-14 |
1977-07-12 |
Eastman Kodak Company |
Electrophotographic apparatus having improved photoconductor regenerative structure and procedure
|
|
US4105776A
(en)
|
1976-06-21 |
1978-08-08 |
E. R. Squibb & Sons, Inc. |
Proline derivatives and related compounds
|
|
US4154839A
(en)
|
1975-11-05 |
1979-05-15 |
Bayer Aktiengesellschaft |
2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine
|
|
FR2330383A1
(fr)
|
1975-11-06 |
1977-06-03 |
Synthelabo |
Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment
|
|
US4046889A
(en)
|
1976-02-13 |
1977-09-06 |
E. R. Squibb & Sons, Inc. |
Azetidine-2-carboxylic acid derivatives
|
|
GB1544872A
(en)
|
1976-06-25 |
1979-04-25 |
Sterling Drug Inc |
4-hydroxyphenylalkanolamine derivatives and preparation thereof
|
|
DE2645710C2
(de)
|
1976-10-09 |
1985-06-27 |
Merck Patent Gmbh, 6100 Darmstadt |
Phenoxy-amino-propanole, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitung
|
|
JPS608117B2
(ja)
|
1977-02-08 |
1985-02-28 |
財団法人微生物化学研究会 |
新生理活性物質エステラスチンおよびその製造法
|
|
DE2719912C3
(de)
|
1977-05-04 |
1979-12-06 |
Bayer Ag, 5090 Leverkusen |
Verfahren zur Isolierung von 0- |4,6-Dideoxy-4- [JJl S-O,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2cyclohexen-1-yl] -amino] - a -D-glucopyranosyl} -(I Pfeil nach rechts 4)-0- a D-glucopyranosyl-(l Pfeil nach rechts 4)-D-glucopyranose aus Kulturbrühen
|
|
US4466972A
(en)
|
1977-06-20 |
1984-08-21 |
Sandoz Ltd. |
Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them
|
|
DE2733747C2
(de)
|
1977-07-27 |
1979-09-27 |
Hoechst Ag, 6000 Frankfurt |
Verfahren zur Herstellung von 2,2 Dichlorhydrazobenzol
|
|
NO154918C
(no)
|
1977-08-27 |
1987-01-14 |
Bayer Ag |
Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
|
|
CA1147342A
(en)
|
1977-10-12 |
1983-05-31 |
Kazuo Imai |
Process of producing novel phenylethanolamine derivatives
|
|
US4188390A
(en)
|
1977-11-05 |
1980-02-12 |
Pfizer Inc. |
Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines
|
|
IT1088554B
(it)
|
1977-11-17 |
1985-06-10 |
F I D I A Spa |
Procedimento sellettivo per la preparazione di derivati della 7-indrossi cumarina
|
|
JPS5953920B2
(ja)
|
1977-12-28 |
1984-12-27 |
東洋醸造株式会社 |
新規なアミノ糖化合物およびその製法
|
|
JPS55301A
(en)
|
1978-02-14 |
1980-01-05 |
Yamanouchi Pharmaceut Co Ltd |
1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
|
|
CA1121290A
(en)
|
1978-02-14 |
1982-04-06 |
Yasuji Suhara |
Amino sugar derivatives
|
|
IT1094076B
(it)
|
1978-04-18 |
1985-07-26 |
Acraf |
Cicloalchiltriazoli
|
|
US4172896A
(en)
|
1978-06-05 |
1979-10-30 |
Dainippon Pharmaceutical Co., Ltd. |
Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same
|
|
SE429652B
(sv)
|
1978-06-30 |
1983-09-19 |
Haessle Ab |
2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
|
|
JPS559058A
(en)
|
1978-07-06 |
1980-01-22 |
Dainippon Pharmaceut Co Ltd |
1-(3-mercapto-2-methylpropanoyl)prolyl amino acid derivative
|
|
DE2845770A1
(de)
|
1978-10-19 |
1980-04-30 |
Schering Ag |
Neue prostacyclin-derivate und verfahren zu ihrer herstellung
|
|
IL58849A
(en)
|
1978-12-11 |
1983-03-31 |
Merck & Co Inc |
Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
|
|
US4231938A
(en)
|
1979-06-15 |
1980-11-04 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
DE2928485A1
(de)
|
1979-07-14 |
1981-01-29 |
Bayer Ag |
Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen
|
|
US4508729A
(en)
|
1979-12-07 |
1985-04-02 |
Adir |
Substituted iminodiacids, their preparation and pharmaceutical compositions containing them
|
|
US4444784A
(en)
|
1980-08-05 |
1984-04-24 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
JPS56110665A
(en)
|
1980-02-08 |
1981-09-01 |
Yamanouchi Pharmaceut Co Ltd |
Sulfamoyl-substituted phenetylamine derivative and its preparation
|
|
SE8004087L
(sv)
|
1980-06-02 |
1981-12-03 |
Haessle Ab |
Nya parasubstituerade 3-fenoxi-1-alkylaminopropanol-2-er med betareceptorblockerande egenskaper, samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma, och metod att behandla akut ...
|
|
MX7065E
(es)
|
1980-06-06 |
1987-04-10 |
Sankyo Co |
Un procedimiento microbiologico para preparar derivados de ml-236b
|
|
US4394382A
(en)
|
1980-06-17 |
1983-07-19 |
Kowa Company, Ltd. |
Dihydrobenzopyran compounds and pharmaceutical composition comprising said compounds
|
|
US4450171A
(en)
|
1980-08-05 |
1984-05-22 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4344949A
(en)
|
1980-10-03 |
1982-08-17 |
Warner-Lambert Company |
Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
|
|
ES505959A0
(es)
|
1980-10-09 |
1982-09-01 |
Hoechst Ag |
Procedimiento para la preparacion de un inactivador de alfa-amilasa
|
|
US4470972A
(en)
|
1981-04-28 |
1984-09-11 |
Schering Corporation |
7-Carboxyalkylaminoacyl-1,4-dithia-7-azaspiro[4.4]-nonane-8-carboxylic acids
|
|
ZA817261B
(en)
|
1980-10-23 |
1982-09-29 |
Schering Corp |
Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them
|
|
US4337201A
(en)
|
1980-12-04 |
1982-06-29 |
E. R. Squibb & Sons, Inc. |
Phosphinylalkanoyl substituted prolines
|
|
FR2496699B1
(fr)
|
1980-12-22 |
1985-06-21 |
Siderurgie Fse Inst Rech |
Lance de soufflage de gaz oxydant, notamment d'oxygene, pour le traitement des metaux en fusion
|
|
DE3166093D1
(en)
|
1981-01-05 |
1984-10-18 |
Takeda Chemical Industries Ltd |
N-substituted pseudo-aminosugars, their production and use
|
|
US4452813A
(en)
|
1981-05-22 |
1984-06-05 |
Taiho Pharmaceutical Company Limited |
Sulfonate derivatives, process for preparing same and antilipemic compositions containing the derivative
|
|
JPS57209270A
(en)
|
1981-06-19 |
1982-12-22 |
Chugai Pharmaceut Co Ltd |
Proline derivative
|
|
US4410520A
(en)
|
1981-11-09 |
1983-10-18 |
Ciba-Geigy Corporation |
3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
|
|
CA1341296C
(en)
|
1981-12-29 |
2001-09-25 |
Hansjorg Urbach |
2-azabicycloalkane-3-carboxylic acid derivatives, processes for their preparation, agents containing these compounds and their use
|
|
US4555502A
(en)
|
1982-09-30 |
1985-11-26 |
Merck & Co., Inc. |
Aminoacyl-containing dipeptide derivatives useful as antihypertensives
|
|
DK161312C
(da)
|
1982-03-11 |
1991-12-09 |
Pfizer |
Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
|
|
US4448784A
(en)
|
1982-04-12 |
1984-05-15 |
Hoechst-Roussel Pharmaceuticals, Inc. |
1-(Aminoalkylphenyl and aminoalkylbenzyl)-indoles and indolines and analgesic method of use thereof
|
|
EP0094159B1
(en)
|
1982-05-10 |
1990-03-14 |
Takeda Chemical Industries, Ltd. |
Dihydropyridine derivatives, their production and use
|
|
JPS6058233B2
(ja)
|
1982-05-24 |
1985-12-19 |
田辺製薬株式会社 |
２−オキソイミダゾリジン誘導体及びその製法
|
|
US4452790A
(en)
|
1982-06-23 |
1984-06-05 |
E. R. Squibb & Sons, Inc. |
Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives
|
|
US4463176A
(en)
|
1982-09-13 |
1984-07-31 |
Mead Johnson & Company |
Process for resolution of optical isomers
|
|
EP0106275B1
(en)
|
1982-10-15 |
1991-03-13 |
Kyowa Hakko Kogyo Co., Ltd. |
1,4-dihydropyridine derivatives
|
|
US4739073A
(en)
|
1983-11-04 |
1988-04-19 |
Sandoz Pharmaceuticals Corp. |
Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
|
|
US4567175A
(en)
|
1983-06-03 |
1986-01-28 |
Tanabe Seiyaku Co., Ltd. |
8-Chloro-1,5-benzothiazepine derivatives
|
|
CA1247547A
(en)
|
1983-06-22 |
1988-12-28 |
Paul Hadvary |
Leucine derivatives
|
|
US4678783B1
(en)
|
1983-11-04 |
1995-04-04 |
Asahi Chemical Ind |
Substituted isoquinolinesulfonyl compounds
|
|
US4654362A
(en)
|
1983-12-05 |
1987-03-31 |
Janssen Pharmaceutica, N.V. |
Derivatives of 2,2'-iminobisethanol
|
|
DK520784A
(da)
|
1984-01-21 |
1985-07-22 |
Hoechst Ag |
Cycliske polypeptider, deres fremstilling og anvendelse
|
|
GB8403866D0
(en)
|
1984-02-14 |
1984-03-21 |
Recordati Chem Pharm |
Diphenylalkylaminoalkyl esters
|
|
JPS60222472A
(ja)
|
1984-03-30 |
1985-11-07 |
Kanebo Ltd |
新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物
|
|
SU1435151A3
(ru)
|
1984-04-10 |
1988-10-30 |
Санкио Компани Лимитед (Фирма) |
Способ получени производных пергидротиазепина или их кислотно-аддитивных фармацевтически приемлемых солей
|
|
US4672068A
(en)
|
1984-05-04 |
1987-06-09 |
Fujirebio Kabushiki Kaisha |
Antihypertensive 1,4-dihydropyridines having a conjugated ester
|
|
NZ212895A
(en)
|
1984-08-22 |
1988-07-28 |
Glaxo Spa |
1,4-dihydropyridine derivatives and pharmaceutical compositions
|
|
US4634765A
(en)
|
1984-12-18 |
1987-01-06 |
Merrell Dow Pharmaceuticals Inc. |
Homodisaccharide hypoglycemic agents
|
|
AU587057B2
(en)
|
1985-07-29 |
1989-08-03 |
Santen Pharmaceutical Co. Ltd. |
1,4-dihydro-3-oxo-2-(substituted phenyl)-benzothiazine derivatives
|
|
US4885284A
(en)
|
1986-01-22 |
1989-12-05 |
Nissan Chemical Industries Ltd. |
Dihydropyridine-5-phosphonic acid cyclic propylene ester
|
|
US4847271A
(en)
|
1986-01-27 |
1989-07-11 |
Merck & Co., Inc. |
Antihypercholesterolemic β-lactones
|
|
GB8608335D0
(en)
|
1986-04-04 |
1986-05-08 |
Pfizer Ltd |
Pharmaceutically acceptable salts
|
|
US5138069A
(en)
|
1986-07-11 |
1992-08-11 |
E. I. Du Pont De Nemours And Company |
Angiotensin II receptor blocking imidazoles
|
|
CA1319144C
(en)
|
1986-11-14 |
1993-06-15 |
Quirico Branca |
Tetrahydronaphthalene derivatives
|
|
US5041432A
(en)
|
1987-01-30 |
1991-08-20 |
E. I. Du Pont De Nemours And Company |
Steroid derivatives useful as hypocholesterolemics
|
|
DE3768658D1
(de)
|
1987-08-03 |
1991-04-18 |
Delagrange Lab |
1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
|
|
JP2569746B2
(ja)
|
1987-08-20 |
1997-01-08 |
日産化学工業株式会社 |
キノリン系メバロノラクトン類
|
|
CA1336714C
(en)
|
1987-08-20 |
1995-08-15 |
Yoshihiro Fujikawa |
Quinoline type mevalonolactone inhibitors of cholesterol biosynthesis
|
|
US5192772A
(en)
|
1987-12-09 |
1993-03-09 |
Nippon Shinyaku Co. Ltd. |
Therapeutic agents
|
|
US4804770A
(en)
|
1988-04-29 |
1989-02-14 |
E. R. Squibb & Sons, Inc. |
Process for preparing a keto-phosphonate intermediate useful in preparing HMG-CoA reductase inhibitors
|
|
EP0344383A1
(en)
|
1988-06-02 |
1989-12-06 |
Merrell Dow Pharmaceuticals Inc. |
Novel alpha-Glucosidase inhibitors
|
|
WO1990003962A1
(en)
|
1988-10-13 |
1990-04-19 |
Sandoz Ag |
Process for the preparation of 7-substituted-hept-6-enoic and -heptanoic acids and derivatives and intermediates thereof
|
|
DE3836675A1
(de)
|
1988-10-28 |
1990-05-03 |
Hoechst Ag |
Glykosidase-inhibitor salbostatin, verfahren zu seiner herstellung und seine verwendung
|
|
AU3732889A
(en)
|
1988-11-11 |
1990-05-28 |
Banyu Pharmaceutical Co., Ltd. |
Substituted allylamine derivatives, process for their preparation and their use
|
|
US5185351A
(en)
|
1989-06-14 |
1993-02-09 |
Smithkline Beecham Corporation |
Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
|
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
|
US5064856A
(en)
|
1989-07-31 |
1991-11-12 |
Merck & Co., Inc. |
Novel hmg-coa synthase inhibitors
|
|
US5391571A
(en)
|
1989-11-15 |
1995-02-21 |
American Home Products Corporation |
Cholesterol ester hydrolase inhibitors
|
|
IL97219A
(en)
|
1990-02-19 |
1995-12-08 |
Ciba Geigy Ag |
Biphenyl substituted aliphatic amino compounds process for their preparation and pharmaceutical compositions containing them
|
|
US5270317A
(en)
|
1990-03-20 |
1993-12-14 |
Elf Sanofi |
N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
|
|
US5051534A
(en)
|
1990-03-22 |
1991-09-24 |
Merrell Dow Pharmaceuticals Inc. |
Novel cyclopropyl squalene derivatives and their use as inhibitors of cholesterol synthesis
|
|
US5102915A
(en)
|
1990-03-22 |
1992-04-07 |
Merrell Dow Pharmaceuticals Inc. |
Cyclopropyl squalene derivatives and their use as inhibitors of cholesterol synthesis
|
|
US5064864A
(en)
|
1990-03-30 |
1991-11-12 |
Merrell Dow Pharmaceuticals Inc. |
Di- and tetra-fluoro analogs of squalene as inhibitors of squalene epoxidase
|
|
US5011859A
(en)
|
1990-03-30 |
1991-04-30 |
Merrell Dow Pharmaceuticals Inc. |
Di- and tetra-fluoro analogs of squalene as inhibitors of squalene epoxidase
|
|
US5196444A
(en)
|
1990-04-27 |
1993-03-23 |
Takeda Chemical Industries, Ltd. |
1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
|
|
US5504078A
(en)
|
1990-06-08 |
1996-04-02 |
Merrell Dow Pharmaceuticals Inc. |
α-glucosidase inhibitors
|
|
US5120729A
(en)
|
1990-06-20 |
1992-06-09 |
Merck & Co., Inc. |
Beta-lactams as antihypercholesterolemics
|
|
ZA915659B
(en)
|
1990-07-25 |
1992-05-27 |
Merrell Dow Pharma |
Novel piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis
|
|
US5026554A
(en)
|
1990-09-13 |
1991-06-25 |
Merck & Co., Inc. |
Method of inhibiting fungal growth using squalene synthetase inhibitors
|
|
US5177080A
(en)
|
1990-12-14 |
1993-01-05 |
Bayer Aktiengesellschaft |
Substituted pyridyl-dihydroxy-heptenoic acid and its salts
|
|
US5084461A
(en)
|
1991-03-27 |
1992-01-28 |
Merrell Dow Pharmaceuticals Inc. |
Azadecalin amides and thioamides as inhibitors of cholesterol biosynthesis
|
|
JP2648897B2
(ja)
|
1991-07-01 |
1997-09-03 |
塩野義製薬株式会社 |
ピリミジン誘導体
|
|
US5274143A
(en)
|
1991-07-23 |
1993-12-28 |
Hoffmann-La Roche Inc. |
Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy-6-undecyl-2H-pyran-2-one and (R)-5,6-dihydro-6-undecyl-2H-pyran-2,4(3H)-dione
|
|
AU3095792A
(en)
|
1991-12-16 |
1993-07-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Novel amino alcohol derivative or salt thereof
|
|
EP0618803A4
(en)
|
1991-12-19 |
1995-03-22 |
Southwest Found Biomed Res |
POLYPEPTIDE INHIBITING PROTEIN TRANSFER TO CHOLESTERYL ESTERS, ANTIBODIES AGAINST SYNTHETIC POLYPEPTIDE AND ANTI-ATHEROSCLEROSIS PROPHYLACTIC AND THERAPEUTIC TREATMENTS.
|
|
CA2098167C
(en)
|
1992-06-24 |
2006-12-19 |
Dorothea Isler |
Foodstuffs and feedstuffs containing a lipase inhibitor
|
|
EP0647234A1
(en)
|
1992-06-26 |
1995-04-12 |
Pfizer Inc. |
Steroidal glycosides for treating hypercholesterolemia
|
|
US5350758A
(en)
|
1992-07-08 |
1994-09-27 |
Merrell Dow Pharmaceuticals Inc. |
Piperidyl sulfonamides and sulfoxamides as inhibitors of cholesterol biosynthesis
|
|
GB9217295D0
(en)
|
1992-08-14 |
1992-09-30 |
Wellcome Found |
Controlled released tablets
|
|
US5728704A
(en)
|
1992-09-28 |
1998-03-17 |
Pfizer Inc. |
Substituted pyridmidines for control of diabetic complications
|
|
FR2697250B1
(fr)
|
1992-10-28 |
1995-01-20 |
Fournier Ind & Sante |
Dérivés de beta,beta-diméthyl-4-pipéridineéthanol et de 1,2,3,6-tétrahydro-beta,beta-diméthyl-4-pyridineéthanol, leur procédé de préparation et leur utilisation en thérapeutique.
|
|
FR2697252B1
(fr)
|
1992-10-28 |
1994-12-09 |
Fournier Ind & Sante |
Dérivés de 1,2,3,5,6,7,8,8a-octahydro-5,5,8a-triméthyl-(8abeta)-6-isoquinolineamine, leur procédé de préparation et leur utilisation en thérapeutique.
|
|
DE4309553A1
(de)
|
1993-03-24 |
1994-09-29 |
Bayer Ag |
Verfahren zur Herstellung von 3R,5S-(+)-Natrium-erythro-(E)-7-(4-(4-flurophenyl)-2,6-diisopropyl-5-methoxymethyl-pyrid-3-yl)-3,5-dihydroxy-hept-6-enoat
|
|
US5358970A
(en)
|
1993-08-12 |
1994-10-25 |
Burroughs Wellcome Co. |
Pharmaceutical composition containing bupropion hydrochloride and a stabilizer
|
|
GB9315856D0
(en)
|
1993-07-30 |
1993-09-15 |
Wellcome Found |
Stabilized pharmaceutical
|
|
US5541231A
(en)
|
1993-07-30 |
1996-07-30 |
Glaxo Wellcome Inc. |
Stabilized Pharmaceutical
|
|
CA2128044C
(en)
|
1993-08-05 |
2007-02-20 |
Klaus-Dieter Bremer |
Pharmaceutical compositions comprising a glucosidase and/or amylase inhibitor, and a lipase inhibitor
|
|
DE69531543T2
(de)
|
1994-06-17 |
2004-06-24 |
F. Hoffmann-La Roche Ag |
N,n'-bis(chinolin-4-yl)-diamin derivate, deren herstellung und deren verwendung als antimalaria-mittel
|
|
EP0784612A1
(en)
|
1994-10-04 |
1997-07-23 |
Fujisawa Pharmaceutical Co., Ltd. |
Urea derivatives and their use as acat-inhibitors
|
|
JPH08143457A
(ja)
|
1994-11-21 |
1996-06-04 |
Microbial Chem Res Found |
酵素阻害剤および高脂血症抑制剤
|
|
AU4515696A
(en)
|
1994-12-12 |
1996-07-03 |
Merck & Co., Inc. |
Substituted 2-aminopyridines as inhibitors of nitric oxide synthase
|
|
US5510379A
(en)
|
1994-12-19 |
1996-04-23 |
Warner-Lambert Company |
Sulfonate ACAT inhibitors
|
|
GB9504066D0
(en)
|
1995-03-01 |
1995-04-19 |
Pharmacia Spa |
Phosphate derivatives of ureas and thioureas
|
|
EP0738510A3
(fr)
|
1995-04-20 |
2005-12-21 |
L'oreal |
Utilisation d'un inhibiteur d'HMG-coenzyme A-reductase pour lutter contre le vieillissement de la peau et pour traiter l'acné. Composition comprenant au moins un inhibiteur HMG-coenzyme A reductase et au moins un actif possédant des propriétes desquamantes
|
|
FI974437A7
(fi)
|
1995-06-06 |
1997-12-05 |
Pfizer |
Substituoituja N-(indoli-2-karbonyyli)amideja ja johdannaisia glykogee nifosforylaasi-inhibiittoreina
|
|
CA2224062C
(en)
|
1995-06-06 |
2001-09-04 |
Pfizer Limited |
Substituted n-(indole-2-carbonyl)-glycinamides and derivatives as glycogen phosphorylase inhibitors
|
|
WO1996040640A1
(en)
|
1995-06-07 |
1996-12-19 |
Pfizer Inc. |
BIPHENYL-2-CARBOXYLIC ACID-TETRAHYDRO-ISOQUINOLIN-6-YL AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND/OR APOLIPOPROTEIN B (Apo B) SECRETION
|
|
NZ325248A
(en)
|
1995-12-23 |
1999-09-29 |
Pfizer Res & Dev |
Quinoline and quinazoline compounds useful in therapy
|
|
JPH105585A
(ja)
|
1996-06-27 |
1998-01-13 |
Toagosei Co Ltd |
リチウムイオン吸着剤
|
|
SE9603285D0
(sv)
|
1996-09-10 |
1996-09-10 |
Astra Ab |
New compounds
|
|
US5874438A
(en)
|
1996-10-11 |
1999-02-23 |
Bayer Aktiengesellschaft |
2,2'-bridged bis-2,4-diaminoquinazolines
|
|
NZ335162A
(en)
|
1996-11-27 |
2000-01-28 |
Pfizer |
Apo b-secretion/mtp inhibitory amides
|
|
DK0999825T3
(da)
|
1997-07-29 |
2004-02-09 |
Alcon Lab Inc |
Oftalmiske sammensætninger indeholdende galactomannanpolymerer og borater
|
|
US6110973A
(en)
|
1998-01-29 |
2000-08-29 |
Sepracor |
Methods for treating obesity and weight gain using optically pure (-)-bupropion
|
|
GT199900147A
(es)
|
1998-09-17 |
1999-09-06 |
|
1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas.
|
|
US6197786B1
(en)
|
1998-09-17 |
2001-03-06 |
Pfizer Inc |
4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
|
|
US8889112B2
(en)
|
1999-09-16 |
2014-11-18 |
Ocularis Pharma, Llc |
Ophthalmic formulations including selective alpha 1 antagonists
|
|
US6521607B1
(en)
|
1999-09-23 |
2003-02-18 |
Pharmacia Corporation |
(R)-chiral halogenated substituted N-phenoxy N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity
|
|
US20040138284A1
(en)
|
2000-02-11 |
2004-07-15 |
Matthias Wiesner |
Indol-3-yl derivatives
|
|
GB0014022D0
(en)
|
2000-06-08 |
2000-08-02 |
Novartis Ag |
Organic compounds
|
|
WO2002020500A2
(en)
|
2000-09-01 |
2002-03-14 |
Icos Corporation |
Materials and methods to potentiate cancer treatment
|
|
EP1217000A1
(en)
|
2000-12-23 |
2002-06-26 |
Aventis Pharma Deutschland GmbH |
Inhibitors of factor Xa and factor VIIa
|
|
WO2002064130A1
(en)
|
2001-02-15 |
2002-08-22 |
Pfizer Products Inc. |
Proliferative activator receptor (ppar) compounds
|
|
EP1360172A1
(en)
|
2001-02-15 |
2003-11-12 |
Pfizer Products Inc. |
Ppar agonists
|
|
CA2442476A1
(en)
|
2001-03-30 |
2002-10-10 |
Pfizer Products Inc. |
Pyridazinone aldose reductase inhibitors
|
|
MXPA03011201A
(es)
|
2001-06-07 |
2004-02-26 |
Lilly Co Eli |
Moduladores de receptores activados por proliferadores de persoxisomas.
|
|
CA2461202C
(en)
|
2001-09-21 |
2011-07-12 |
Donald Pinto |
Lactam-containing compounds and derivatives thereof as factor xa inhibitors
|
|
AU2003209321A1
(en)
|
2002-01-18 |
2003-07-30 |
Pharmacia Corporation |
Substituted pyridazinones as inhibitors of p38
|
|
US6875780B2
(en)
|
2002-04-05 |
2005-04-05 |
Warner-Lambert Company |
Compounds that modulate PPAR activity and methods for their preparation
|
|
US7312214B2
(en)
|
2002-05-10 |
2007-12-25 |
Bristol-Myers Squibb Company |
1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors
|
|
US20040087590A1
(en)
|
2002-08-23 |
2004-05-06 |
University Of Connecticut |
Novel biphenyl and biphenyl-like cannabinoids
|
|
AU2003286711A1
(en)
|
2002-10-25 |
2004-05-13 |
Vertex Pharmaceuticals Incorporated |
Indazolinone compositions useful as kinase inhibitors
|
|
AU2003299790A1
(en)
*
|
2002-12-20 |
2004-07-22 |
Bayer Pharmaceuticals Corporation |
Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
|
|
US20050197350A1
(en)
|
2003-03-31 |
2005-09-08 |
Taisho Pharmaceutical Co., Ltd. |
Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof
|
|
KR20050114283A
(ko)
|
2003-04-22 |
2005-12-05 |
아바니르 파마슈티컬스 |
고콜레스테롤혈증을 치료하기 위한 역 콜레스테롤 수송의매개제
|
|
US6933289B2
(en)
|
2003-07-01 |
2005-08-23 |
Allergan, Inc. |
Inhibition of irritating side effects associated with use of a topical ophthalmic medication
|
|
CA2534484A1
(en)
|
2003-08-07 |
2005-02-17 |
Allergan, Inc. |
Compositions for delivery of therapeutics into the eyes and methods for making and using same
|
|
US20050059744A1
(en)
|
2003-09-12 |
2005-03-17 |
Allergan, Inc. |
Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions
|
|
MXJL06000069A
(es)
|
2004-06-09 |
2007-04-10 |
Avanir Pharmaceuticals |
Derivados heterociclicos para el tratamiento de hiperlipidemia y enfermedades relacionadas.
|
|
US7829712B2
(en)
|
2004-09-20 |
2010-11-09 |
Xenon Pharmaceuticals Inc. |
Pyridazine derivatives for inhibiting human stearoyl-CoA-desaturase
|
|
US20080090863A1
(en)
|
2004-09-30 |
2008-04-17 |
Taisho Pharmaceutical Co., Ltd. |
Pyridine Derivatives and Their Use as Medicaments for Treating Diseases Related to Mch Receptor
|
|
US7381732B2
(en)
|
2004-10-26 |
2008-06-03 |
Bristol-Myers Squibb Company |
Pyrazolobenzamides and derivatives as factor Xa inhibitors
|
|
EP1814856A1
(en)
|
2004-11-12 |
2007-08-08 |
Galapagos N.V. |
Nitrogen heteroaromatic compounds which bind to the active site of protein kinase enzymes
|
|
GB0428082D0
(en)
|
2004-12-22 |
2005-01-26 |
Welcome Trust The Ltd |
Therapeutic compounds
|
|
JP2008531596A
(ja)
*
|
2005-02-25 |
2008-08-14 |
ライジェル ファーマシューティカルズ， インコーポレイテッド |
Ｈｃｖ感染を治療または予防するのに有用なベンゾイソチアゾール
|
|
CA2603830A1
(en)
|
2005-05-24 |
2006-11-30 |
Pharmacia & Upjohn Co Llc |
PYRIDINE [2,3-B] PYRAZINONES
|
|
JP5118029B2
(ja)
|
2005-06-14 |
2013-01-16 |
タイゲン バイオテクノロジー カンパニー，リミテッド |
ピリミジン化合物
|
|
US20070203236A1
(en)
|
2006-01-11 |
2007-08-30 |
Smith Jeffrey W |
Novel antagonists of the human fatty acid synthase thioesterase
|
|
JP2007291087A
(ja)
|
2006-03-29 |
2007-11-08 |
Taisho Pharmaceut Co Ltd |
ピリジン誘導体及びその使用に関連する治療法
|
|
UA95644C2
(ru)
|
2006-07-25 |
2011-08-25 |
Сефалон, Инк. |
Пиридазиноновые производные, фармацевтическая композиция и способ лечения заболеваний
|
|
US20080255155A1
(en)
|
2006-10-18 |
2008-10-16 |
Stephane Raeppel |
Kinase inhibitors and uses thereof
|
|
WO2008061796A2
(en)
|
2006-11-24 |
2008-05-29 |
Ac Immune Sa |
Compounds for the treatment of diseases associated with amyloid or amyloid-like proteins
|
|
KR101442288B1
(ko)
|
2006-12-13 |
2014-09-19 |
지보당 네덜란드 서비시즈 비.브이. |
카복실산과 퓨린, 피리미딘, 뉴클레오사이드 또는 뉴클레오타이드의 향미 조절 유도체
|
|
EP2205639B1
(en)
*
|
2007-10-26 |
2015-12-23 |
Merck Sharp & Dohme Corp. |
Anti-pcsk9 and methods for treating lipid and cholesterol disorders
|
|
US7803809B2
(en)
|
2008-11-12 |
2010-09-28 |
Amgen Inc. |
Substituted pyrano [2,3-b] pyridinamine compounds as beta-secretase modulators and methods of use
|
|
CA2726588C
(en)
|
2008-06-03 |
2019-04-16 |
Karl Kossen |
Compounds and methods for treating inflammatory and fibrotic disorders
|
|
WO2010048149A2
(en)
|
2008-10-20 |
2010-04-29 |
Kalypsys, Inc. |
Heterocyclic modulators of gpr119 for treatment of disease
|
|
NZ624963A
(en)
|
2009-04-29 |
2016-07-29 |
Amarin Pharmaceuticals Ie Ltd |
Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
|
|
WO2011006000A1
(en)
|
2009-07-08 |
2011-01-13 |
Haiyan Liu |
Berberine derivatives useful for modulating lipid levels and their methods of synthesis
|
|
WO2011008931A2
(en)
|
2009-07-15 |
2011-01-20 |
Cystic Fibrosis Foundation Therapeutics, Inc. |
Arylpyrimidine compounds and combination therapy comprising same for treating cystic fibrosis & related disorders
|
|
MX2012001504A
(es)
|
2009-08-05 |
2012-06-01 |
Versitech Ltd |
Compuestos antivirales y metodos para elaborarlos y usarlos.
|
|
US20120219558A1
(en)
|
2009-09-25 |
2012-08-30 |
Yan Ni |
Antagonists of pcsk9
|
|
WO2011053783A2
(en)
|
2009-10-30 |
2011-05-05 |
Merck Sharp & Dohme Corp. |
Ax213 and ax132 pcsk9 antagonists and variants
|
|
CN102596249A
(zh)
|
2009-10-30 |
2012-07-18 |
默沙东公司 |
Ax1和ax189 pcsk9拮抗剂和变体
|
|
AR079336A1
(es)
|
2009-12-11 |
2012-01-18 |
Irm Llc |
Antagonistas de la pro-proteina convertasa-subtilisina/quexina tipo 9 (pcsk9)
|
|
EA022983B1
(ru)
|
2010-04-13 |
2016-04-29 |
Бристол-Майерс Сквибб Компани |
Белки на основе структурного домена фибронектина, связывающие pcsk9
|
|
AU2011253058A1
(en)
*
|
2010-05-13 |
2012-12-06 |
Amgen Inc. |
Heteroaryloxycarbocyclyl compounds as PDE10 inhibitors
|
|
WO2011147199A1
(en)
|
2010-05-28 |
2011-12-01 |
Versitech Limited |
Compounds and methods for treating viral infections
|
|
CN102933559B
(zh)
*
|
2010-06-04 |
2016-01-27 |
兴和株式会社 |
光学活性二苄胺衍生物及其制备方法
|
|
WO2011163612A1
(en)
|
2010-06-24 |
2011-12-29 |
Trustees Of Tufts College |
Niacin mimetics, and methods of use thereof
|
|
JP5925771B2
(ja)
|
2010-06-24 |
2016-05-25 |
トラスティーズ オブ タフツ カレッジ |
ナイアシン模倣体、およびその使用方法
|
|
EP2592933B1
(en)
|
2010-07-16 |
2017-04-05 |
Anderson Gaweco |
Mif inhibitors and their uses
|
|
WO2012016133A2
(en)
|
2010-07-29 |
2012-02-02 |
President And Fellows Of Harvard College |
Ros1 kinase inhibitors for the treatment of glioblastoma and other p53-deficient cancers
|
|
WO2012054438A1
(en)
|
2010-10-22 |
2012-04-26 |
Schering Corporation |
Anti-pcsk9
|
|
WO2012088438A1
(en)
|
2010-12-22 |
2012-06-28 |
Eutropics Pharmaceuticals, Inc. |
Compositions and methods useful for treating diseases
|
|
KR20130118925A
(ko)
|
2010-12-22 |
2013-10-30 |
제넨테크, 인크. |
항-pcsk9 항체 및 사용 방법
|
|
PL3395836T3
(pl)
|
2011-01-28 |
2021-12-13 |
Sanofi Biotechnology |
Ludzkie przeciwciała przeciwko pcsk9 do zastosowania w sposobach leczenia konkretnych grup osobników
|
|
JP2014506878A
(ja)
|
2011-01-28 |
2014-03-20 |
ノバルティス アーゲー |
Ｃｄｋ９阻害剤としての置換ビ−ヘテロアリール化合物およびそれらの使用
|
|
AU2012214251A1
(en)
|
2011-02-11 |
2013-09-12 |
Novartis Ag |
PCSK9 antagonists
|
|
US9133164B2
(en)
|
2011-04-13 |
2015-09-15 |
Innov88 Llc |
MIF inhibitors and their uses
|
|
JOP20200043A1
(ar)
|
2011-05-10 |
2017-06-16 |
Amgen Inc |
طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول
|
|
WO2012162635A1
(en)
|
2011-05-26 |
2012-11-29 |
Sunovion Pharmaceuticals Inc. |
Metabotropic glutamate receptors 5 modulators and methods of use thereof
|
|
WO2012170607A2
(en)
|
2011-06-10 |
2012-12-13 |
Novartis Ag |
Use of pcsk9 antagonists
|
|
WO2012168491A1
(en)
|
2011-06-10 |
2012-12-13 |
Novartis Ag |
Pharmaceutical formulations of pcsk9 antagonists
|
|
EP2721063A4
(en)
|
2011-06-20 |
2015-01-14 |
Hoffmann La Roche |
PCSK9 BINDING POLYPEPTIDES AND METHOD OF USE THEREOF
|
|
CN104093423A
(zh)
|
2011-07-14 |
2014-10-08 |
辉瑞公司 |
使用抗pcsk9抗体的治疗
|
|
US8815909B2
(en)
|
2011-07-18 |
2014-08-26 |
Bristol-Myers Squibb Company |
Diaminocyclohexane compounds and uses thereof
|
|
AR087305A1
(es)
|
2011-07-28 |
2014-03-12 |
Regeneron Pharma |
Formulaciones estabilizadas que contienen anticuerpos anti-pcsk9, metodo de preparacion y kit
|
|
JP5741850B2
(ja)
|
2011-09-13 |
2015-07-01 |
コニカミノルタ株式会社 |
光学フィルム、それを含む偏光板および液晶表示装置
|
|
AR087715A1
(es)
|
2011-09-16 |
2014-04-09 |
Lilly Co Eli |
Anticuerpos anti pcsk9 y usos de los mismos
|
|
ES2992345T3
(es)
|
2011-09-16 |
2024-12-11 |
Regeneron Pharma |
Métodos para reducir los niveles de lipoproteína(a) mediante la administración de un inhibidor de la proproteína convertasa subtilisina kexina-9 (PCSK9)
|
|
WO2013091103A1
(en)
|
2011-12-20 |
2013-06-27 |
Adaerata, Limited Partnership |
Single domain antibodies as inhibitors of pcsk9
|
|
US10028926B2
(en)
|
2012-01-06 |
2018-07-24 |
Gemphire Therapeutics Inc. |
Methods of reducing risk of cardiovascular disease
|
|
TW201348231A
(zh)
*
|
2012-02-29 |
2013-12-01 |
Amgen Inc |
雜雙環化合物
|
|
WO2013134047A2
(en)
*
|
2012-03-07 |
2013-09-12 |
The Mclean Hospital Corporation |
Aminoquinoline derivatives and uses thereof
|
|
JPWO2013137371A1
(ja)
*
|
2012-03-15 |
2015-08-03 |
興和株式会社 |
新規ピリミジン化合物及びそれらを含有する医薬
|
|
WO2013148284A1
(en)
|
2012-03-29 |
2013-10-03 |
Genentech, Inc. |
Antibodies that bind to a pcsk9 cleavage site and methods of use
|
|
WO2013158939A1
(en)
|
2012-04-18 |
2013-10-24 |
Hemoshear, Llc |
In vitro model for pathological or physiologic conditions
|
|
EA039663B1
(ru)
|
2012-05-03 |
2022-02-24 |
Амген Инк. |
Применение антитела против pcsk9 для снижения сывороточного холестерина лпнп и лечения связанных с холестерином расстройств
|
|
US9255154B2
(en)
|
2012-05-08 |
2016-02-09 |
Alderbio Holdings, Llc |
Anti-PCSK9 antibodies and use thereof
|
|
CA2874244A1
(en)
|
2012-05-25 |
2013-11-28 |
Catabasis Pharmaceuticals, Inc. |
Methods of lowering proprotein convertase subtilisin/kexin type 9 (pcsk9)
|
|
EP2861624A1
(en)
|
2012-06-15 |
2015-04-22 |
F. Hoffmann-La Roche AG |
Anti-pcsk9 antibodies, formulations, dosing, and methods of use
|
|
US20150190369A1
(en)
|
2012-07-03 |
2015-07-09 |
Majambu Mbikay |
Quercetin-3-glucoside and uses thereof
|
|
US9434695B2
(en)
|
2012-07-18 |
2016-09-06 |
Sunshine Lake Pharma Co., Ltd |
Nitrogenous heterocyclic derivatives and their application in drugs
|
|
TWI596115B
(zh)
|
2012-08-13 |
2017-08-21 |
再生元醫藥公司 |
具有ｐＨ－依賴性結合特性之抗－ＰＣＳＫ９抗體
|
|
UA116217C2
(uk)
|
2012-10-09 |
2018-02-26 |
Санофі |
Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
|
|
AR092924A1
(es)
|
2012-10-09 |
2015-05-06 |
Sanofi Sa |
Derivados de pirrolidinona como moduladores de gpr119 para el tratamiento de diabetes, obesidad, dislipidemia y trastornos relacionados
|
|
HK1211232A1
(en)
|
2012-12-21 |
2016-05-20 |
Sanofi |
Exendin-4 derivatives as dual glp1/gip or trigonal glp1/gip/glucagon agonists
|
|
WO2014107739A1
(en)
|
2013-01-07 |
2014-07-10 |
Eleven Biotherapeutics, Inc. |
Antibodies against pcsk9
|
|
TWI644899B
(zh)
|
2013-02-04 |
2018-12-21 |
健生藥品公司 |
Ｆｌａｐ調節劑
|
|
AU2014211727B2
(en)
|
2013-02-04 |
2018-07-26 |
Prexton Therapeutics Sa |
Positive allosteric modulators of mGluR3
|
|
HK1219048A1
(zh)
|
2013-02-15 |
2017-03-24 |
Srx Cardio, Llc |
前蛋白转化酶枯草杆菌蛋白酶/kexin 9型(pcsk9)变构结合配体来调节低密度脂蛋白(ldl)血清水平
|
|
SI3527563T1
(sl)
*
|
2013-03-12 |
2022-01-31 |
Vertex Pharmaceuticals Incorporated |
Inhibitorji DNA-PK
|
|
HK1213194A1
(zh)
|
2013-03-14 |
2016-06-30 |
Daiichi Sankyo Co., Ltd. |
用於新型的结合蛋白质pcsk9
|
|
CA2905237A1
(en)
|
2013-03-15 |
2014-09-18 |
Adaerata, Limited Partnership |
Small molecule modulators of pcsk9 and methods of use thereof
|
|
CN105228616B
(zh)
|
2013-03-15 |
2019-05-03 |
实发生物医学公司 |
抗前蛋白转化酶枯草杆菌蛋白酶Kexin 9型（抗PCSK9）化合物及其用于治疗和/或预防心血管疾病的方法
|
|
JP2016514668A
(ja)
|
2013-03-15 |
2016-05-23 |
アムジエン・インコーポレーテツド |
プロタンパク質コンベルターゼスブチリシンケクシン９型に結合するヒト抗原結合タンパク質
|
|
WO2014150395A1
(en)
|
2013-03-15 |
2014-09-25 |
Shifa Biomedical Corporation |
Anti-pcsk9 compounds and methods for the treatment and/or prevention of cardiovascular diseases
|
|
US20160032014A1
(en)
|
2013-03-15 |
2016-02-04 |
Amgen Inc. |
Human antigen binding proteins that bind to proprotein convertase subtilisin kexin type 9
|
|
MX2015014666A
(es)
|
2013-04-17 |
2016-03-01 |
Pfizer |
Derivados de n-piperidin-3-ilbenzamida para tratar enfermedades cardiovasculares.
|
|
US10111953B2
(en)
|
2013-05-30 |
2018-10-30 |
Regeneron Pharmaceuticals, Inc. |
Methods for reducing remnant cholesterol and other lipoprotein fractions by administering an inhibitor of proprotein convertase subtilisin kexin-9 (PCSK9)
|
|
TWI682780B
(zh)
|
2013-05-30 |
2020-01-21 |
美商再生元醫藥公司 |
醫藥組成物用於製造治療與ｐｃｓｋ９功能獲得性突變有關之體染色體顯性高膽固醇血症的藥物之用途
|
|
TW202021614A
(zh)
|
2013-06-07 |
2020-06-16 |
法商賽諾菲生物技術公司 |
藉由投與ｐｃｓｋ９抑制劑抑制動脈粥狀硬化的方法
|
|
WO2014201173A1
(en)
|
2013-06-12 |
2014-12-18 |
Amgen Inc. |
Bicyclic sulfonamide compounds as sodium channel inhibitors
|
|
JP6267792B2
(ja)
|
2013-06-28 |
2018-01-24 |
アムジエン・インコーポレーテツド |
ホモ接合性家族性高コレステロール血症の治療方法
|
|
AR092240A1
(es)
|
2013-08-26 |
2015-04-08 |
Sunshine Lake Pharma Co Ltd |
Derivados heterociclicos nitrogenados y su aplicacion en farmacos
|
|
CN105658232A
(zh)
|
2013-08-30 |
2016-06-08 |
阿尔莫生物科技股份有限公司 |
使用白细胞介素-10治疗疾病和病症的方法
|
|
KR20220048051A
(ko)
|
2013-10-11 |
2022-04-19 |
사노피 바이오테크놀로지 |
고지혈증을 치료하기 위한 ｐｃｓｋ9 억제제의 용도
|
|
CN104558685B
(zh)
|
2013-10-24 |
2017-09-29 |
中国石油化工股份有限公司 |
一种磷氮膨胀型阻燃剂及其合成方法
|
|
JP2017019724A
(ja)
|
2013-10-25 |
2017-01-26 |
第一三共株式会社 |
置換ピリジン化合物および他の医薬の組み合わせ
|
|
MX2016006226A
(es)
|
2013-11-12 |
2016-09-07 |
Sanofi Biotechnology |
Regimenes de dosificacion para uso con inhibidores de pcsk9.
|
|
HK1224186A1
(zh)
|
2013-11-20 |
2017-08-18 |
Cymabay Therapeutics, Inc. |
纯阖家族型高胆固醇血症的治疗
|
|
EP3080148A2
(en)
|
2013-12-11 |
2016-10-19 |
Glycotope GmbH |
Glycosylated glycophorin peptides
|
|
TW201609799A
(zh)
|
2013-12-13 |
2016-03-16 |
賽諾菲公司 |
雙重ｇｌｐ－１／ｇｉｐ受體促效劑
|
|
WO2015086732A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Exendin-4 peptide analogues
|
|
WO2015086733A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Dual glp-1/glucagon receptor agonists
|
|
WO2015086728A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Exendin-4 peptide analogues as dual glp-1/gip receptor agonists
|
|
EP3080152A1
(en)
|
2013-12-13 |
2016-10-19 |
Sanofi |
Non-acylated exendin-4 peptide analogues
|
|
EP3080155A1
(en)
|
2013-12-13 |
2016-10-19 |
Sanofi |
Exendin-4 peptide analogues as dual glp-1/glucagon receptor agonists
|
|
CN106029096A
(zh)
|
2014-02-14 |
2016-10-12 |
瑞泽恩制药公司 |
用于治疗具有未被中等剂量他汀疗法充分控制的高胆固醇血症的患者的方法
|
|
LT3119757T
(lt)
|
2014-03-17 |
2018-07-10 |
Pfizer Inc. |
Diacilglicerolio aciltransferazės 2 inhibitoriai, skirti panaudoti metabolinių ir susijusių ligų gydyme
|
|
WO2015140079A1
(en)
|
2014-03-17 |
2015-09-24 |
Sanofi |
Methods for treating subjects with primary hypercholesterolemia that is not adequately controlled
|
|
AU2015231713B2
(en)
|
2014-03-17 |
2020-11-19 |
Regeneron Pharmaceuticals, Inc. |
Methods for reducing cardiovascular risk
|
|
EP3126346B1
(en)
|
2014-04-04 |
2018-07-11 |
Sanofi |
Substituted indanone compounds as gpr119 modulators for the treatment of diabetes, obesity, dyslipidemia and related disorders
|
|
AR099937A1
(es)
|
2014-04-04 |
2016-08-31 |
Sanofi Sa |
Compuestos de isoindolinona como moduladores de gpr119 para el tratamiento de diabetes, obesidad, dislipidemia y trastornos relacionados
|
|
AR099936A1
(es)
|
2014-04-04 |
2016-08-31 |
Sanofi Sa |
Heterociclos condensados sustituidos como moduladores de gpr119 para el tratamiento de la diabetes, obesidad, dislipidemia y trastornos relacionados
|
|
TW201625669A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑
|
|
TW201625670A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑
|
|
TW201625668A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物
|
|
EP3148537B1
(en)
|
2014-05-30 |
2018-09-26 |
Université Paris Descartes |
Cyclic compounds having a 1,3 diamino-functionality for use in the treatment of hiv infection
|
|
WO2015187295A2
(en)
|
2014-06-02 |
2015-12-10 |
Armo Biosciences, Inc. |
Methods of lowering serum cholesterol
|
|
US9932381B2
(en)
|
2014-06-18 |
2018-04-03 |
Sanofi |
Exendin-4 derivatives as selective glucagon receptor agonists
|
|
TWI677489B
(zh)
|
2014-06-20 |
2019-11-21 |
美商基利科學股份有限公司 |
多環型胺甲醯基吡啶酮化合物之合成
|
|
WO2015200438A1
(en)
|
2014-06-24 |
2015-12-30 |
Eleven Biotherapeutics, Inc. |
High affinity antibodies against pcsk9
|
|
RU2723018C2
(ru)
|
2014-07-16 |
2020-06-08 |
Санофи Байотекнолоджи |
Способы лечения пациентов с высоким риском возникновения сердечно-сосудистых заболеваний, имеющих гиперхолестеринемию
|
|
ES2826443T3
(es)
|
2014-09-25 |
2021-05-18 |
Araxes Pharma Llc |
Inhibidores de proteínas mutantes KRAS G12C
|
|
US10245254B2
(en)
|
2014-10-03 |
2019-04-02 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Glutaminase inhibitors
|
|
WO2016055901A1
(en)
|
2014-10-08 |
2016-04-14 |
Pfizer Inc. |
Substituted amide compounds
|
|
BR112017015273A2
(pt)
|
2015-01-20 |
2018-01-09 |
Merial Inc. |
compostos e composições antihelmínticos e método de utilizações dos mesmos
|
|
WO2016127102A2
(en)
|
2015-02-06 |
2016-08-11 |
Ernesto Abel-Santos |
Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis
|
|
AR103954A1
(es)
|
2015-03-18 |
2017-06-14 |
Zealand Pharma As |
Análogos de amilina
|
|
EP3973958A3
(en)
|
2015-03-20 |
2022-06-22 |
Aarhus Universitet |
Inhibitors of pcsk9 for treatment of lipoprotein metabolism disorders
|
|
US10336802B2
(en)
|
2015-04-16 |
2019-07-02 |
Zealand Pharma A/S |
Acylated glucagon analogue
|
|
AU2016348638A1
(en)
|
2015-11-06 |
2018-06-07 |
Gemphire Therapeutics Inc. |
Gemcabene combinations for the treatment of cardiovascular disease
|
|
TW201731867A
(zh)
|
2015-12-02 |
2017-09-16 |
賽諾菲公司 |
Ｆｇｆ２１變異體
|
|
IL303850A
(en)
|
2015-12-11 |
2023-08-01 |
Univ Pennsylvania |
Gene therapy for treating familial hypercholesterolemia
|
|
WO2017125506A1
(en)
*
|
2016-01-20 |
2017-07-27 |
Janssen Sciences Ireland Uc |
Aryl substituted pyrimidines for use in influenza virus infection
|
|
CN108697677A
(zh)
|
2016-02-26 |
2018-10-23 |
燿石治疗公司 |
对正接受降脂疗法的纯合型家族性高胆固醇血症患者的治疗
|
|
CN109152784B
(zh)
|
2016-03-16 |
2021-12-28 |
库拉肿瘤学公司 |
经取代的menin-mll抑制剂及使用方法
|
|
JP2019513802A
(ja)
|
2016-04-14 |
2019-05-30 |
ルシー マイケル |
組み合わせ組成物およびその使用方法
|
|
TW201808888A
(zh)
|
2016-05-05 |
2018-03-16 |
嘉來克生命科學有限責任公司 |
整合應激途徑之調節劑
|
|
AU2017292184A1
(en)
|
2016-07-08 |
2019-02-07 |
Staten Biotechnology B.V. |
Anti-Apoc3 antibodies and methods of use thereof
|
|
JP2019532049A
(ja)
|
2016-09-15 |
2019-11-07 |
ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドＴｈｅ Ｂｒｉｇｈａｍ ａｎｄ Ｗｏｍｅｎ’ｓ Ｈｏｓｐｉｔａｌ， Ｉｎｃ． |
Ｄｒｐ１阻害を通じたｐｃｓｋ９およびｌｄｌｒのモジュレーション法
|
|
LT3529360T
(lt)
|
2016-10-18 |
2024-07-25 |
Novartis Ag |
Metodai, skirti širdies ir kraujagyslių ligų prevencijai mažinant proproteinų konvertazės subtilizino keksino 9 (pcsk9) baltymo kiekį
|
|
SG11201903945XA
(en)
|
2016-11-10 |
2019-05-30 |
Csl Ltd |
Reconstituted high density lipoprotein treatment of myocardial infarction
|
|
JOP20190112A1
(ar)
|
2016-11-14 |
2019-05-14 |
Amgen Inc |
علاجات مدمجة لتصلب الشرايين، شاملة مرض قلبي وعائي تصلبي
|
|
WO2018106820A1
(en)
|
2016-12-07 |
2018-06-14 |
Kura Oncology, Inc. |
Methods of promoting beta cell proliferation
|
|
WO2018106818A1
(en)
|
2016-12-07 |
2018-06-14 |
Kura Oncology, Inc. |
Methods of promoting beta cell proliferation
|
|
CN110267964B
(zh)
|
2016-12-13 |
2022-05-03 |
百时美施贵宝公司 |
作为IL-12、IL-23及/或IFNα响应调节剂的经取代的杂芳基氧化膦化合物
|
|
CN110637027B
(zh)
|
2017-02-08 |
2024-08-30 |
百时美施贵宝公司 |
包含药代动力学增强子的修饰的松弛素多肽及其用途
|
|
EP3579782B1
(en)
|
2017-02-08 |
2024-05-01 |
Brooke Schumm |
Intra-operative radiation therapy capsule with cylindrical shell radiation containment shutter system
|
|
AR110988A1
(es)
|
2017-02-21 |
2019-05-22 |
Sanofi Sa |
Compuestos de azetidina como moduladores de gpr119 para el tratamiento de la diabetes, la obesidad, la dislipidemia y trastornos relacionados
|
|
WO2018165718A1
(en)
*
|
2017-03-17 |
2018-09-20 |
Cardio Therapeutics Pty Ltd |
Heterocyclic inhibitors of pcsk9
|
|
CN110691779B
(zh)
|
2017-03-24 |
2023-10-10 |
库拉肿瘤学公司 |
治疗血液系统恶性肿瘤和尤因肉瘤的方法
|
|
JP2020517242A
(ja)
|
2017-04-21 |
2020-06-18 |
スターテン・バイオテクノロジー・ベー・フェー |
抗ＡｐｏＣ３抗体およびその使用方法
|
|
IL271149B2
(en)
|
2017-06-14 |
2024-05-01 |
Trevena Inc |
Compounds for modulating s1p1 activity and methods of using the same
|
|
WO2019001379A1
(zh)
|
2017-06-26 |
2019-01-03 |
深圳市塔吉瑞生物医药有限公司 |
用于抑制激酶活性的吲唑类化合物及其组合物及应用
|
|
CN109384712B
(zh)
|
2017-08-14 |
2021-05-07 |
北京宽厚医药科技有限公司 |
靶向nk1受体拮抗剂及其在化疗所致恶心、呕吐治疗中的应用
|
|
WO2019079701A1
(en)
|
2017-10-20 |
2019-04-25 |
Dana-Farber Cancer Institute, Inc. |
HETEROBIFUNCTIONAL COMPOUNDS HAVING IMPROVED SPECIFICITY FOR BRD4 BROMODOMAINE
|
|
EP3687538B1
(en)
|
2017-10-30 |
2024-04-17 |
Montreal Heart Institute |
Methods of treating elevated plasma cholesterol
|
|
KR20200074975A
(ko)
|
2017-10-31 |
2020-06-25 |
스태튼 바이오테크놀로지 비.브이. |
항-ApoC3 항체 및 이의 사용 방법
|
|
UY37957A
(es)
|
2017-11-02 |
2019-05-31 |
Abbvie Inc |
Moduladores de la vía de estrés integrada
|
|
MX2020005210A
(es)
|
2017-11-21 |
2020-08-20 |
Bristol Myers Squibb Co |
Compuestos de heteroarilo sustituidos con alquilamida de piridinsulfona.
|
|
WO2019111225A1
(en)
|
2017-12-08 |
2019-06-13 |
Avaliv Therapeutics |
Compounds and methods for the treatment of non‑alcoholic steatohepatitis
|
|
WO2019126071A1
(en)
|
2017-12-18 |
2019-06-27 |
Regeneron Pharmaceuticals, Inc. |
Bispecific antigen binding molecules that bind leptin receptor and/or gp130, and methods of use thereof
|
|
CA3088788A1
(en)
|
2018-01-17 |
2019-07-25 |
Vertex Pharmaceuticals Incorporated |
Dna-pk inhibitors
|
|
US11513131B2
(en)
|
2018-01-22 |
2022-11-29 |
Global Genomics Group, LLC |
Low density lipoprotein triglycerides (LDL-TG) as a biomarker of cardiovascular disease and uses thereof
|
|
JP2021512051A
(ja)
|
2018-01-23 |
2021-05-13 |
ギラ セラピューティクス インコーポレイテッドＧｉｌａ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． |
ペプチドｙｙ薬学的調剤物、組成物、および方法
|
|
JP2021517141A
(ja)
|
2018-03-09 |
2021-07-15 |
ザ・ブリガーム・アンド・ウーメンズ・ホスピタル・インコーポレーテッド |
心血管疾患のための組み合わせ治療
|
|
EP3768667B1
(en)
|
2018-03-22 |
2023-04-12 |
Bristol-Myers Squibb Company |
Heterocyclic compounds comprising pyridine useful as modulators of il-12, il-23 and/or ifn alpha responses
|
|
CN110384801B
(zh)
|
2018-04-20 |
2021-09-14 |
中国科学院上海药物研究所 |
miRNA552簇的微小RNA在治疗LDLC相关代谢性疾病中的应用
|
|
ES2969982T3
(es)
|
2018-04-24 |
2024-05-23 |
Vertex Pharma |
Compuestos de pteridinona y usos de los mismos
|
|
US20190374526A1
(en)
|
2018-06-06 |
2019-12-12 |
Merck Sharp & Dohme Corp. |
Substituted Heterocyclic Compounds as Inhibitors of PRDM9
|
|
US11442072B2
(en)
|
2018-07-10 |
2022-09-13 |
Jenny and Antti Wihuri Foundation |
Method for measuring LDL aggregation
|
|
CR20210110A
(es)
|
2018-08-31 |
2021-05-13 |
Pfizer |
Combinaciones para tratamiento de ehna/ehgna y enfermedades relacionadas
|
|
WO2020070678A2
(en)
|
2018-10-03 |
2020-04-09 |
Staten Biotechnology B.V. |
Antibodies specific for human and cynomolgus apoc3 and methods of use thereof
|
|
AU2019364336B2
(en)
|
2018-10-22 |
2023-11-16 |
Alumis Inc. |
TYK2 inhibitors and uses thereof
|
|
CN113286885A
(zh)
|
2018-11-09 |
2021-08-20 |
诺华股份有限公司 |
用靶向apo(a)的经缀合的反义化合物降低心血管事件的风险的方法
|
|
CA3122035A1
(en)
|
2018-12-06 |
2020-06-11 |
Zora Biosciences Oy |
Biomarkers for cardiovascular events
|
|
SG11202107614PA
(en)
|
2019-01-18 |
2021-08-30 |
Astrazeneca Ab |
Pcsk9 inhibitors and methods of use thereof
|
|
AU2020209216A1
(en)
|
2019-01-18 |
2021-08-26 |
Astrazeneca Ab |
PCSK9 inhibitors and methods of use thereof
|
|
CN111484480B
(zh)
|
2019-01-29 |
2023-08-11 |
上海翰森生物医药科技有限公司 |
一种多环类衍生物抑制剂、其制备方法和应用
|
|
WO2020160518A1
(en)
|
2019-02-01 |
2020-08-06 |
Memorial Sloan Kettering Cancer Center |
Senolytic car-t cells targeting upar, a cell surface and secreted senescence biomarker
|
|
WO2020214753A1
(en)
|
2019-04-17 |
2020-10-22 |
Ngm Biopharmaceuticals, Inc. |
Combination therapy for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
|
|
WO2020234726A1
(en)
|
2019-05-20 |
2020-11-26 |
Pfizer Inc. |
Combinations comprising benzodioxol as glp-1r agonists for use in the treatment of nash/nafld and related diseases
|
|
JP2023506732A
(ja)
|
2019-12-10 |
2023-02-20 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
ホモ接合型家族性高コレステロール血症を処置するためのｐｃｓｋ９阻害剤の使用
|
|
WO2021209808A1
(en)
|
2020-04-16 |
2021-10-21 |
Abionyx Pharma Sa |
Cer-001 therapy for treating kidney disease
|
|
CN113713107B
(zh)
|
2020-05-26 |
2022-09-23 |
中国科学院上海药物研究所 |
miRNA552簇的微小RNA在治疗糖脂代谢病中的应用
|
|
CA3179316A1
(en)
|
2020-05-29 |
2021-12-02 |
Andrew W. HAMER |
Pcsk9 inhibitors and methods of use thereof to treat cholesterol-related disorders
|
|
TWI897977B
(zh)
|
2020-06-10 |
2025-09-21 |
荷蘭商菲林公司 |
用於治療動脈粥樣硬化性心血管疾病之藥物化合物
|
|
WO2022028317A1
(en)
|
2020-08-05 |
2022-02-10 |
Rezubio Pharmaceuticals Co., Ltd |
Antidiabetic compounds and compositions
|
|
WO2022029334A1
(en)
|
2020-08-07 |
2022-02-10 |
Gbiotech S.À.R.L. |
Combination therapies for treating coronavirus infection
|
|
WO2022040371A1
(en)
|
2020-08-19 |
2022-02-24 |
Biogen Ma Inc. |
Methods for treating hypercholesterolemia
|
|
JP2023543409A
(ja)
|
2020-09-15 |
2023-10-16 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
疼痛に対するｌｅｐｒアゴニストの使用
|
|
PL4232448T3
(pl)
|
2020-10-20 |
2025-10-13 |
Halo Therapeutics Ltd |
Agoniści receptora 1 wolnych kwasów tłuszczowych i ich zastosowanie w chorobach związanych z wymienionym receptorem
|
|
WO2022098841A1
(en)
|
2020-11-05 |
2022-05-12 |
Amgen Inc. |
METHODS FOR TREATING ATHEROSCLEROTIC CARDIOVASCULAR DISEASE WITH LPA-TARGETED RNAi CONSTRUCTS
|
|
US12419888B2
(en)
|
2020-12-11 |
2025-09-23 |
Institut De Cardiologie De Montreal |
Methods of treating elevated plasma cholesterol
|
|
WO2022123120A1
(en)
|
2020-12-11 |
2022-06-16 |
Helsingin Yliopisto |
Method for determining a likelihood of a subject to respond to lipid lowering therapy
|
|
PL4294257T3
(pl)
|
2021-02-22 |
2026-02-09 |
Regeneron Pharmaceuticals, Inc. |
Sposób diagnozowania i leczenia częściowej lipodystrofii
|
|
WO2022182918A1
(en)
|
2021-02-25 |
2022-09-01 |
Icahn School Of Medicine At Mount Sinai |
Methods for inhibiting inflammation and progression of atherosclerotic plaques and cardiovascular events in patients with cerebro- and cardio-vascular disease
|
|
EP4312978A2
(en)
|
2021-03-27 |
2024-02-07 |
TRX Biosciences Limited |
Compositions having improved bioavailability of therapeutics
|
|
AU2022299514A1
(en)
|
2021-06-24 |
2024-01-18 |
Sirnaomics, Inc. |
Products and compositions
|
|
EP4359441A1
(en)
|
2021-06-25 |
2024-05-01 |
Amgen Inc. |
Treatment of cardiovascular disease with trem-1 antigen binding proteins
|
|
WO2023285583A1
(en)
|
2021-07-14 |
2023-01-19 |
Eternygen Uk Ltd. |
5,6,7,8-tetrahydro-2,6- and 2,7-naphthyridine derivatives for use in the treatment of diseases responsive to citrate transporter modulation
|
|
WO2023052783A1
(en)
|
2021-09-30 |
2023-04-06 |
Sitryx Therapeutics Limited |
Novel compounds
|
|
WO2023079294A1
(en)
|
2021-11-05 |
2023-05-11 |
Sitryx Therapeutics Limited |
Phthalazine derivatives as pyruvate kinase modulators
|
|
EP4446307A4
(en)
|
2021-11-12 |
2025-12-10 |
Shenzhen Jingtai Tech Co Ltd |
ASPARTIC ACID DERIVATIVE AND ITS USE IN THE TREATMENT OF METABOLIC DISEASES SUCH AS HEPATIC FIBROSIS AND NON-ALCOHOLIC HEPATITIS
|
|
CN114277032A
(zh)
|
2021-12-31 |
2022-04-05 |
华中科技大学同济医学院附属协和医院 |
一种低密度脂蛋白受体基因突变体及其应用
|
|
US20250223281A1
(en)
|
2022-01-14 |
2025-07-10 |
Rezubio Pharmaceuticals Co., Ltd |
Antidiabetic compounds and compositions
|
|
TW202345865A
(zh)
|
2022-01-24 |
2023-12-01 |
大陸商上海舶望製藥有限公司 |
抑制LPA(Apo(a))蛋白表達的組合物和方法
|
|
CN116617390A
(zh)
|
2022-02-11 |
2023-08-22 |
武汉大学 |
Asgr1抑制剂在促进胆固醇外排和治疗非酒精性脂肪性肝病中的应用
|
|
US20250177377A1
(en)
|
2022-03-11 |
2025-06-05 |
University Of Florida Research Foundation, Incorporated |
Targeting ptchd1 and neuronal cholesterol to enhance safety of opioid analgesics
|
|
US20230338419A1
(en)
|
2022-03-21 |
2023-10-26 |
The Trustees Of The University Of Pennsylvania |
Methods and apparatus for diagnosis and detection of cardiac allograft vasculopathy
|
|
CN119161484A
(zh)
|
2022-04-25 |
2024-12-20 |
武汉大学 |
抗asgr1单克隆抗体及其应用
|
|
US20250295724A1
(en)
|
2022-05-13 |
2025-09-25 |
Zhejiang Yangshengtang Institute Of Natural Medication Co., Ltd. |
Composition of malus niedzwetzkyana dieck and prunus cerasifera ehrhart and use thereof in terms of resisting atherosclerosis
|
|
CN115581694A
(zh)
|
2022-11-10 |
2023-01-10 |
正大青春宝药业有限公司 |
洋川芎内脂i在制备治疗高血脂症药物中的应用
|
|
CN117180404A
(zh)
|
2023-10-24 |
2023-12-08 |
清华大学 |
Cholesin在调节胆固醇稳态中的用途
|
|
CN117482076A
(zh)
|
2023-11-24 |
2024-02-02 |
中国人民解放军陆军军医大学第二附属医院 |
甲硫氨酸类化合物在制备pcsk9抑制剂中的应用
|