|
US900629A
(en)
|
1906-02-15 |
1908-10-06 |
Robert Wettel |
Combination latch and key lock.
|
|
CA2297294C
(en)
|
1989-05-15 |
2005-11-08 |
Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic |
Phosphonomethoxymethylpurine/pyrimidine derivatives
|
|
US5233031A
(en)
|
1991-09-23 |
1993-08-03 |
University Of Rochester |
Phosphoramidate analogs of 2'-deoxyuridine
|
|
IT1249732B
(it)
|
1991-11-26 |
1995-03-09 |
Angeletti P Ist Richerche Bio |
Oligonucleotidi antisenso.
|
|
DE9314572U1
(de)
|
1993-09-27 |
1995-02-02 |
Dr. Hahn GmbH & Co. KG., 41189 Mönchengladbach |
Band für Türen, Fenster u.dgl.
|
|
GB9505025D0
(en)
|
1995-03-13 |
1995-05-03 |
Medical Res Council |
Chemical compounds
|
|
US5977061A
(en)
|
1995-04-21 |
1999-11-02 |
Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic |
N6 - substituted nucleotide analagues and their use
|
|
US7517858B1
(en)
|
1995-06-07 |
2009-04-14 |
The Regents Of The University Of California |
Prodrugs of pharmaceuticals with improved bioavailability
|
|
ES2201235T3
(es)
|
1996-10-07 |
2004-03-16 |
Julius Blum Gesellschaft M.B.H. |
Juego de guiado de extraccion para cajones.
|
|
EP0961775B1
(en)
|
1996-10-16 |
2004-07-14 |
ICN Pharmaceuticals, Inc. |
Purine l-nucleosides, analogs and uses thereof
|
|
ZA986614B
(en)
|
1997-07-25 |
1999-01-27 |
Gilead Sciences |
Nucleotide analog composition
|
|
EA008609B1
(ru)
|
1998-02-25 |
2007-06-29 |
Эмори Юниверсити |
2'-фторнуклеозиды
|
|
JP2002531413A
(ja)
|
1998-11-30 |
2002-09-24 |
ノボザイムス アクティーゼルスカブ |
抗真菌性ポリペプチドを含む抗−ふけ組成物
|
|
JP2002536452A
(ja)
|
1999-02-12 |
2002-10-29 |
グラクソ グループ リミテッド |
抗ウイルス剤としての（１Ｒ，ｃｉｓ）−４−（６−アミノ−９Ｈ−プリン−９−イル）−２−シクロペンテン−１−メタノールのホスホルアミダート、ならびに一、二および三リン酸エステル
|
|
IN191496B
(enExample)
|
1999-07-30 |
2003-12-06 |
Ranbaxy Lab Ltd |
|
|
MXPA02005490A
(es)
|
1999-12-03 |
2004-09-10 |
Univ California San Diego |
Compuestos de fosfonato.
|
|
KR20100003313A
(ko)
|
2000-04-13 |
2010-01-07 |
파마셋 인코포레이티드 |
간염 바이러스 감염 치료를 위한 3'- 또는 2'-하이드록시메틸 치환된 뉴클레오시드 유도체
|
|
MY164523A
(en)
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
|
EA200601591A1
(ru)
|
2000-05-26 |
2007-02-27 |
Айденикс (Кайман) Лимитед |
Применение рибонуклеозидных соединений для лечения флавивирусных и пестивирусных инфекций
|
|
CA2426187C
(en)
|
2000-10-18 |
2011-08-16 |
Pharmasset Limited |
Modified nucleosides for the treatment of viral infections and abnormal cellular proliferation
|
|
EP2180064A3
(en)
|
2000-10-18 |
2010-08-11 |
Pharmasset, Inc. |
Multiplex quantification of nucleic acids in diseased cells
|
|
CN1267446C
(zh)
|
2001-01-22 |
2006-08-02 |
默克公司 |
作为依赖于rna的rna病毒聚合酶的抑制剂的核苷衍生物
|
|
US7105499B2
(en)
|
2001-01-22 |
2006-09-12 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
US8481712B2
(en)
|
2001-01-22 |
2013-07-09 |
Merck Sharp & Dohme Corp. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
GB0112617D0
(en)
|
2001-05-23 |
2001-07-18 |
Hoffmann La Roche |
Antiviral nucleoside derivatives
|
|
GB0114286D0
(en)
|
2001-06-12 |
2001-08-01 |
Hoffmann La Roche |
Nucleoside Derivatives
|
|
US6949522B2
(en)
|
2001-06-22 |
2005-09-27 |
Pharmasset, Inc. |
β-2′- or 3′-halonucleosides
|
|
US7138376B2
(en)
|
2001-09-28 |
2006-11-21 |
Idenix Pharmaceuticals, Inc. |
Methods and compositions for treating hepatitis C virus using 4'-modified nucleosides
|
|
GB2383042A
(en)
|
2001-10-18 |
2003-06-18 |
Cipla Ltd |
Amorphous alendronate sodium
|
|
WO2003039523A2
(en)
|
2001-11-05 |
2003-05-15 |
Exiqon A/S |
OLIGONUCLEOTIDES MODIFIED WITH NOVEL α-L-RNA ANALOGUES
|
|
US7388002B2
(en)
|
2001-11-14 |
2008-06-17 |
Biocryst Pharmaceuticals, Inc. |
Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases
|
|
WO2003063771A2
(en)
|
2001-12-14 |
2003-08-07 |
Pharmasset Ltd. |
N4-acylcytosine nucleosides for treatment of viral iinfections
|
|
EP1569658A4
(en)
|
2001-12-20 |
2007-05-30 |
Pharmassett Ltd |
TREATMENT OF EBV AND KHSV INFECTION AND AN ASSOCIATED ABNORMAL CELL PROLIFERATION
|
|
WO2003062256A1
(en)
|
2002-01-17 |
2003-07-31 |
Ribapharm Inc. |
2'-beta-modified-6-substituted adenosine analogs and their use as antiviral agents
|
|
EP1476169B1
(en)
|
2002-02-13 |
2013-03-20 |
Merck Sharp & Dohme Corp. |
Inhibiting orthopoxvirus replication with nucleoside compounds
|
|
CA2477741A1
(en)
|
2002-02-28 |
2003-09-04 |
Biota, Inc. |
Nucleotide mimics and their prodrugs
|
|
US20040063658A1
(en)
|
2002-05-06 |
2004-04-01 |
Roberts Christopher Don |
Nucleoside derivatives for treating hepatitis C virus infection
|
|
WO2004003138A2
(en)
|
2002-06-27 |
2004-01-08 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
|
|
AU2003247084B9
(en)
*
|
2002-06-28 |
2018-07-26 |
Centre National De La Recherche Scientifique |
Modified 2' and 3'-nucleoside prodrugs for treating flaviridae infections
|
|
CA2489552A1
(en)
|
2002-06-28 |
2004-01-08 |
Idenix (Cayman) Limited |
2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
|
|
CN101172993A
(zh)
|
2002-06-28 |
2008-05-07 |
埃迪尼克斯(开曼)有限公司 |
用于治疗黄病毒感染的2′－c－甲基－3′－o－l－缬氨酸酯核糖呋喃基胞苷
|
|
US7608600B2
(en)
|
2002-06-28 |
2009-10-27 |
Idenix Pharmaceuticals, Inc. |
Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
|
|
RS114104A
(sr)
|
2002-06-28 |
2007-02-05 |
Idenix (Cayman) Limited, |
2'i 3'-nukleozidni prolekovi za lečenje flaviviridae infekcija
|
|
US7323449B2
(en)
|
2002-07-24 |
2008-01-29 |
Merck & Co., Inc. |
Thionucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
US20040067877A1
(en)
|
2002-08-01 |
2004-04-08 |
Schinazi Raymond F. |
2', 3'-Dideoxynucleoside analogues for the treatment or prevention of Flaviviridae infections
|
|
US8093380B2
(en)
|
2002-08-01 |
2012-01-10 |
Pharmasset, Inc. |
Compounds with the bicyclo[4.2.1]nonane system for the treatment of Flaviviridae infections
|
|
AU2003259735A1
(en)
|
2002-08-08 |
2004-02-25 |
Sirna Therapeutics, Inc. |
Small-mer compositions and methods of use
|
|
ES2624353T3
(es)
|
2002-11-15 |
2017-07-13 |
Idenix Pharmaceuticals Llc |
2'-Metil nucleósidos en combinación con interferón y mutación de Flaviviridae
|
|
TWI294882B
(en)
|
2002-12-09 |
2008-03-21 |
Hoffmann La Roche |
Anhydrous crystalline azido cytosine hemisulfate derivative
|
|
NZ540913A
(en)
|
2002-12-23 |
2008-02-29 |
Idenix Cayman Ltd |
Process for the production of 3'-nucleoside prodrugs
|
|
AR043006A1
(es)
|
2003-02-12 |
2005-07-13 |
Merck & Co Inc |
Proceso para preparar ribonucleosidos ramificados
|
|
WO2005011709A1
(en)
|
2003-02-19 |
2005-02-10 |
Yale University |
Anti-viral nucleoside analogs and methods for treating viral infections, especially hiv infections
|
|
US20050020675A1
(en)
|
2003-02-21 |
2005-01-27 |
Parthasaradhi Reddy Bandi |
Bicalutamide polymorphs
|
|
US7691603B2
(en)
|
2003-04-09 |
2010-04-06 |
Novo Nordisk A/S |
Intracellular formation of peptide conjugates
|
|
US7429565B2
(en)
|
2003-04-25 |
2008-09-30 |
Gilead Sciences, Inc. |
Antiviral phosphonate analogs
|
|
US20040259934A1
(en)
|
2003-05-01 |
2004-12-23 |
Olsen David B. |
Inhibiting Coronaviridae viral replication and treating Coronaviridae viral infection with nucleoside compounds
|
|
EP1656093A2
(en)
|
2003-05-14 |
2006-05-17 |
Idenix (Cayman) Limited |
Nucleosides for treatment of infection by corona viruses, toga viruses and picorna viruses
|
|
US20040229839A1
(en)
|
2003-05-14 |
2004-11-18 |
Biocryst Pharmaceuticals, Inc. |
Substituted nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases
|
|
WO2004106356A1
(en)
|
2003-05-27 |
2004-12-09 |
Syddansk Universitet |
Functionalized nucleotide derivatives
|
|
HUE029877T2
(en)
|
2003-05-30 |
2017-04-28 |
Gilead Pharmasset Llc |
Modified fluorinated nucleoside analogues
|
|
EP1644395B1
(en)
|
2003-06-19 |
2006-11-22 |
F. Hoffmann-La Roche Ag |
Processes for preparing 4'azido nucleoside derivatives
|
|
GB0317009D0
(en)
|
2003-07-21 |
2003-08-27 |
Univ Cardiff |
Chemical compounds
|
|
JP2007501185A
(ja)
|
2003-07-25 |
2007-01-25 |
イデニクス（ケイマン）リミテツド |
Ｃ型肝炎を含むフラビウイルス関連疾患を治療するためのプリンヌクレオシド類似体
|
|
DE10335061B4
(de)
|
2003-07-31 |
2005-11-17 |
Wacker-Chemie Gmbh |
Verfahren zur Herstellung von OH-geschützten [4-(2,6-damino-9H-purin-9-yl)-1,3-dioxolan-2-yl]methanol-Derivaten
|
|
NZ546055A
(en)
|
2003-08-27 |
2010-05-28 |
Biota Scient Management |
Novel tricyclic nucleosides or nucleotides as therapeutic agents
|
|
GB0401088D0
(en)
|
2004-01-19 |
2004-02-18 |
Univ Cardiff |
Phosphoramidate derivatives
|
|
WO2005090370A1
(en)
|
2004-02-05 |
2005-09-29 |
The Regents Of The University Of California |
Pharmacologically active agents containing esterified phosphonates and methods for use thereof
|
|
US20050182252A1
(en)
|
2004-02-13 |
2005-08-18 |
Reddy K. R. |
Novel 2'-C-methyl nucleoside derivatives
|
|
AU2005254057B2
(en)
|
2004-06-15 |
2011-02-17 |
Isis Pharmaceuticals, Inc. |
C-purine nucleoside analogs as inhibitors of RNA-dependent RNA viral polymerase
|
|
US7560434B2
(en)
|
2004-06-22 |
2009-07-14 |
Biocryst Pharmaceuticals, Inc. |
AZA nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases
|
|
CA2571079A1
(en)
|
2004-06-24 |
2006-02-02 |
Merck & Co., Inc. |
Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection
|
|
JP2008504985A
(ja)
|
2004-06-29 |
2008-02-21 |
エーブリー デニソン コーポレイション |
エラストマーと不織ウェブとの間の結合が改善された、不織布−エラストマー積層体
|
|
CN101023094B
(zh)
|
2004-07-21 |
2011-05-18 |
法莫赛特股份有限公司 |
烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
|
|
PL3109244T3
(pl)
|
2004-09-14 |
2019-09-30 |
Gilead Pharmasset Llc |
Wytwarzanie 2'fluoro-2'-alkilo-podstawionych lub innych ewentualnie podstawionych rybofuranozylopirymidyn i puryn oraz ich pochodnych
|
|
WO2006050161A2
(en)
|
2004-10-29 |
2006-05-11 |
Biocryst Pharmaceuticals, Inc. |
Therapeutic furopyrimidines and thienopyrimidines
|
|
WO2006063149A1
(en)
|
2004-12-09 |
2006-06-15 |
Regents Of The University Of Minnesota |
Nucleosides with antiviral and anticancer activity
|
|
US7495006B2
(en)
|
2004-12-10 |
2009-02-24 |
Emory University |
2′ and 3′-substituted cyclobutyl nucleoside analogs for the treatment of viral infections and abnormal cellular proliferation
|
|
EP1828217A2
(en)
|
2004-12-16 |
2007-09-05 |
Febit Biotech GmbH |
Polymerase-independent analysis of the sequence of polynucleotides
|
|
CA2600886A1
(en)
|
2005-03-08 |
2006-09-14 |
Biota Scientific Management Pty Ltd. |
Bicyclic nucleosides and nucleotides as therapeutic agents
|
|
GB0505781D0
(en)
|
2005-03-21 |
2005-04-27 |
Univ Cardiff |
Chemical compounds
|
|
WO2006102533A2
(en)
|
2005-03-23 |
2006-09-28 |
Neopharm, Inc. |
Pharmaceutically active lipid-based formulation of nucleoside-lipid conjugates
|
|
EP2537520A1
(en)
|
2005-03-29 |
2012-12-26 |
Biocryst Pharmaceuticals, Inc. |
Hepatics C therapies
|
|
WO2006130217A2
(en)
|
2005-04-01 |
2006-12-07 |
The Regents Of The University Of California |
Substituted phosphate esters of nucleoside phosphonates
|
|
WO2006121820A1
(en)
|
2005-05-05 |
2006-11-16 |
Valeant Research & Development |
Phosphoramidate prodrugs for treatment of viral infection
|
|
US7632821B2
(en)
|
2005-08-09 |
2009-12-15 |
Merck & Co., Inc. |
Ribonucleoside cyclic acetal derivatives for the treatment of RNA-dependent RNA viral infection
|
|
AU2006279720A1
(en)
|
2005-08-12 |
2007-02-22 |
Merck & Co., Inc. |
Novel 2'-C-methyl and 4'-C-methyl nucleoside derivatives
|
|
CN101287472B
(zh)
|
2005-08-15 |
2011-10-12 |
弗·哈夫曼-拉罗切有限公司 |
抗病毒的4'-取代前核苷酸的氨基磷酸酯类化合物
|
|
US7888330B2
(en)
|
2005-11-09 |
2011-02-15 |
Wayne State University |
Phosphoramidate derivatives of FAU
|
|
EP1987050A2
(en)
|
2006-02-14 |
2008-11-05 |
Merck & Co., Inc. |
Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection
|
|
US8895531B2
(en)
|
2006-03-23 |
2014-11-25 |
Rfs Pharma Llc |
2′-fluoronucleoside phosphonates as antiviral agents
|
|
EP2012799B1
(en)
|
2006-05-03 |
2016-08-24 |
Chimerix, Inc. |
Metabolically stable alkoxyalkyl esters of antiviral or antiproliferative phosphonates, nucleoside phosphonates and nucleoside phosphates
|
|
WO2008005542A2
(en)
|
2006-07-07 |
2008-01-10 |
Gilead Sciences, Inc., |
Antiviral phosphinate compounds
|
|
GB0614947D0
(en)
|
2006-07-27 |
2006-09-06 |
Isis Innovation |
Epitope reduction therapy
|
|
KR101057239B1
(ko)
|
2006-10-10 |
2011-08-16 |
에프. 호프만-라 로슈 아게 |
뉴클레오사이드 리보푸라노실 피리미딘의 제조
|
|
PL216525B1
(pl)
|
2006-10-17 |
2014-04-30 |
Ct Badań Molekularnych I Makromolekularnych Polskiej Akademii Nauk |
5'-O-[(N-acylo)amidoditiofosforano] nukleozydy oraz sposób wytwarzania 5'-O-[(N-acylo)amidofosforano]-,5'-O-[(N-acylo)amidotiofosforano]-, 5'-O-[(N-acylo)amidoditiofosforano]nukleozydów
|
|
GB0623493D0
(en)
|
2006-11-24 |
2007-01-03 |
Univ Cardiff |
Chemical compounds
|
|
JP2010513484A
(ja)
|
2006-12-20 |
2010-04-30 |
メルク・シャープ・エンド・ドーム・コーポレイション |
Ｒｎａ依存性ｒｎａウイルス感染治療用ヌクレオシド環状ホスホロアミデート
|
|
US7951789B2
(en)
*
|
2006-12-28 |
2011-05-31 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
AU2007342367B2
(en)
|
2007-01-05 |
2012-12-06 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Nucleoside aryl phosphoramidates for the treatment of RNA-dependent RNA viral infection
|
|
PL2114980T3
(pl)
|
2007-01-12 |
2012-11-30 |
Biocryst Pharm Inc |
Przeciwwirusowe analogi nukleozydów
|
|
MX2009008139A
(es)
|
2007-01-31 |
2009-08-12 |
Alios Biopharma Inc |
Derivdos de 2-5a y su uso como agentes anti-cancer, antivirales y anti-parasitos.
|
|
WO2008100447A2
(en)
|
2007-02-09 |
2008-08-21 |
Gilead Sciences, Inc. |
Nucleoside analogs for antiviral treatment
|
|
AU2012241173B2
(en)
*
|
2007-03-30 |
2014-09-25 |
Gilead Sciences, Inc. |
Nucleoside Phosphoramidate Prodrugs
|
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
|
EP1980568A1
(de)
|
2007-04-13 |
2008-10-15 |
Eberhard Karls Universität Tübingen |
Ethinylierte Heterodinucleosidphosphatanaloga, Verfahren zu deren Herstellung und deren Verwendung
|
|
AU2008251555B2
(en)
|
2007-05-10 |
2012-08-30 |
Biocryst Pharmaceuticals, Inc. |
Tetrahydrofuro [3 4-D] dioxolane compounds for use in the treatment of viral infections and cancer
|
|
WO2008143846A1
(en)
|
2007-05-14 |
2008-11-27 |
Rfs Pharma, Llc |
Azido purine nucleosides for treatment of viral infections
|
|
EP2014771B1
(en)
|
2007-06-25 |
2014-12-03 |
Anadys Pharmaceuticals, Inc. |
Continuous enzymatic hydrolysis process
|
|
GB0712494D0
(en)
|
2007-06-27 |
2007-08-08 |
Isis Innovation |
Substrate reduction therapy
|
|
US20090060872A1
(en)
|
2007-08-31 |
2009-03-05 |
Idenix Pharmaceuticals, Inc. |
Phosphadiazine hcv polymerase inhibitors v
|
|
US20090318380A1
(en)
|
2007-11-20 |
2009-12-24 |
Pharmasset, Inc. |
2',4'-substituted nucleosides as antiviral agents
|
|
WO2009086201A1
(en)
|
2007-12-21 |
2009-07-09 |
Alios Biopharma, Inc. |
2-5a analogs and their use as anti-cancer, anti-viral and anti- paras iti c agents
|
|
US20090176732A1
(en)
|
2007-12-21 |
2009-07-09 |
Alios Biopharma Inc. |
Protected nucleotide analogs
|
|
TW200942243A
(en)
|
2008-03-05 |
2009-10-16 |
Biocryst Pharm Inc |
Antiviral therapeutic agents
|
|
US8415321B2
(en)
|
2008-04-15 |
2013-04-09 |
Raymond F. Schinazi |
Nucleoside derivatives for treatment of Caliciviridae infections, including Norovirus infections
|
|
WO2009132123A1
(en)
|
2008-04-23 |
2009-10-29 |
Gilead Sciences, Inc. |
Carba-nucleoside analogs for antiviral treatment
|
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
|
TW201012814A
(en)
|
2008-07-01 |
2010-04-01 |
Centocor Ortho Biotech Products L P |
Cyclopropyl polymerase inhibitors
|
|
WO2010002877A2
(en)
|
2008-07-03 |
2010-01-07 |
Biota Scientific Management |
Bycyclic nucleosides and nucleotides as therapeutic agents
|
|
US8736709B2
(en)
|
2008-07-11 |
2014-05-27 |
The Invention Science Fund I, Llc |
Spectral improvement of digital camera color images
|
|
CA2734486A1
(en)
|
2008-08-20 |
2010-02-25 |
Southern Research Institute |
Substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
EP2331511A1
(en)
|
2008-08-20 |
2011-06-15 |
Schering Corporation |
Ethynyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
ES2439009T3
(es)
|
2008-08-20 |
2014-01-21 |
Merck Sharp & Dohme Corp. |
Derivados de piridina y pirimidina sustituidos con etenilo y su uso en el tratamiento de infecciones virales
|
|
CA2734488A1
(en)
|
2008-08-20 |
2010-02-25 |
Southern Research Institute |
Azo-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
PA8852101A1
(es)
|
2008-12-08 |
2010-07-27 |
Medivir Ab |
Nucleótidos uracil ciclopropílicos
|
|
US8815829B2
(en)
*
|
2008-12-09 |
2014-08-26 |
Rfs Pharma, Llc |
3′-azido purine nucleotide prodrugs for treatment of viral infections
|
|
PA8855801A1
(es)
|
2008-12-23 |
2010-07-27 |
|
Sintesis de nucleosidos de purina
|
|
AR074882A1
(es)
|
2008-12-23 |
2011-02-16 |
Pharmasset Inc |
Analogos de nucleosidos
|
|
SG172359A1
(en)
|
2008-12-23 |
2011-07-28 |
Pharmasset Inc |
Nucleoside phosphoramidates
|
|
AU2010203416C1
(en)
|
2009-01-09 |
2013-07-25 |
Inhibitex, Inc. |
Phosphoramidate derivatives of guanosine nucleoside compounds for treatment of viral infections
|
|
JP2012517443A
(ja)
*
|
2009-02-06 |
2012-08-02 |
アールエフエス ファーマ，エルエルシー |
癌及びウイルス感染の治療のためのプリンヌクレオシド一リン酸プロドラッグ
|
|
KR101724759B1
(ko)
|
2009-02-10 |
2017-04-07 |
길리애드 사이언시즈, 인코포레이티드 |
항바이러스 치료를 위한 카르바-뉴클레오시드 유사체
|
|
AR075584A1
(es)
|
2009-02-27 |
2011-04-20 |
Intermune Inc |
COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO.
|
|
EP2403860B1
(en)
|
2009-03-04 |
2015-11-04 |
IDENIX Pharmaceuticals, Inc. |
Phosphothiophene and phosphothiazole as hcv polymerase inhibitors
|
|
WO2010108135A1
(en)
|
2009-03-20 |
2010-09-23 |
Alios Biopharma, Inc. |
Protected nucleotide analogs
|
|
US20100249068A1
(en)
|
2009-03-20 |
2010-09-30 |
Alios Biopharma, Inc. |
Substituted nucleoside and nucleotide analogs
|
|
JO3027B1
(ar)
|
2009-05-14 |
2016-09-05 |
Janssen Products Lp |
نيوكليوسيدات يوراسيل سبيرواوكسيتان
|
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
|
TWI598358B
(zh)
|
2009-05-20 |
2017-09-11 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
|
EP2264169A1
(en)
|
2009-06-15 |
2010-12-22 |
Qiagen GmbH |
Modified siNA
|
|
WO2011005860A2
(en)
|
2009-07-07 |
2011-01-13 |
Alnylam Pharmaceuticals, Inc. |
5' phosphate mimics
|
|
US8455451B2
(en)
|
2009-09-21 |
2013-06-04 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
US7973013B2
(en)
|
2009-09-21 |
2011-07-05 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
EP2483288B1
(en)
|
2009-09-29 |
2016-11-16 |
Janssen Products, L.P. |
Phosphoramidate derivatives of nucleosides
|
|
US8816074B2
(en)
|
2009-11-16 |
2014-08-26 |
University of Georgia Foundation, Inc. |
2′-fluoro-6′-methylene carbocyclic nucleosides and methods of treating viral infections
|
|
KR101961601B1
(ko)
|
2009-11-16 |
2019-03-25 |
유니버시티 오브 조지아 리서치 파운데이션, 인코포레이티드 |
바이러스 감염 치료를 위한 ２＇―플루오로―６＇―메틸렌 카보사이클릭 뉴클레오사이드 및 방법
|
|
BR112012014899A2
(pt)
|
2009-12-18 |
2017-03-14 |
Idenix Pharmaceuticals Inc |
composto, composição farmacêutica, método para tratar ou prevenir uma infecção por vírus de hepatite c em um sujeito, método para tratar , prevenir ou melhorar um ou mais sintomas de uma doença hepática ou distúrbio associado a uma infecção por vírus de hepatite c em um sujeito, método para inibir a replicação de um vírus em um hospedeiro, método para inibir a replicação de um vírus
|
|
US8333309B2
(en)
|
2010-03-02 |
2012-12-18 |
Kenneth Riddleberger |
Hunter's adjustable encapsulating scent adsorption system with combination pack and detachably securable flexible funnel for human odor adsorption
|
|
PL3290428T3
(pl)
|
2010-03-31 |
2022-02-07 |
Gilead Pharmasset Llc |
Tabletka zawierająca krystaliczny (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-diokso-3,4-dihydropirymidyn-1(2H)-ylo)-4-fluoro-3-hydroksy-4-metylotetrahydrofuran-2-ylo)metoksy)(fenoksy)fosforylo)amino)propanian izopropylu
|
|
ES2516466T3
(es)
|
2010-03-31 |
2014-10-30 |
Gilead Pharmasset Llc |
Síntesis estereoselectiva de agentes activos que contienen fósforo
|
|
CA2795054A1
(en)
|
2010-04-01 |
2011-10-06 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
CN102939291B
(zh)
|
2010-04-14 |
2016-09-07 |
加利福尼亚大学董事会 |
用于病毒感染治疗的具有降低的毒性的膦酸酯
|
|
TW201201815A
(en)
|
2010-05-28 |
2012-01-16 |
Gilead Sciences Inc |
1'-substituted-carba-nucleoside prodrugs for antiviral treatment
|
|
EP2596004B1
(en)
|
2010-07-19 |
2014-09-10 |
Gilead Sciences, Inc. |
Methods for the preparation of diasteromerically pure phosphoramidate prodrugs
|
|
EP2963034A1
(en)
|
2010-08-26 |
2016-01-06 |
RFS Pharma, LLC. |
Potent and selective inhibitors of hepatitis c virus
|
|
NZ607996A
(en)
*
|
2010-09-22 |
2014-07-25 |
Alios Biopharma Inc |
Substituted nucleotide analogs
|
|
WO2012040126A1
(en)
|
2010-09-22 |
2012-03-29 |
Alios Biopharma, Inc. |
Substituted nucleotide analogs
|
|
US8877731B2
(en)
|
2010-09-22 |
2014-11-04 |
Alios Biopharma, Inc. |
Azido nucleosides and nucleotide analogs
|
|
AR083221A1
(es)
|
2010-09-29 |
2013-02-06 |
Univ Nac Quilmes |
Proceso para producir dialquilfosfotriesteres de nucleosidos mediante transesterificacion enzimatica y desproteccion de los mismos para producir nucleosidos monofosfato
|
|
WO2012048013A2
(en)
|
2010-10-06 |
2012-04-12 |
Inhibitex, Inc. |
Phosphorodiamidate derivatives of guanosine nucleoside compounds for treatment of viral injections
|
|
PL2638054T3
(pl)
|
2010-11-10 |
2015-05-29 |
Janssen Products Lp |
Fosforoamidany nukleozydów uracylo-spirooksetanowych
|
|
EP2646453A1
(en)
|
2010-11-30 |
2013-10-09 |
Gilead Pharmasset LLC |
Compounds
|
|
US8772474B2
(en)
|
2010-12-22 |
2014-07-08 |
Alios Biopharma, Inc. |
Cyclic nucleotide analogs
|
|
US9351989B2
(en)
|
2010-12-29 |
2016-05-31 |
Inhibitex, Inc. |
Substituted purine nucleosides, phosphoroamidate and phosphorodiamidate derivatives for treatment of viral infections
|
|
CN103403014B
(zh)
|
2011-01-03 |
2016-07-06 |
河南美泰宝生物制药有限公司 |
O-(经取代的苯甲基)氨基磷酸酯化合物及其治疗用途
|
|
SI3447061T1
(sl)
|
2011-03-01 |
2022-02-28 |
NuCana plc |
Farmacevtska formulacija, ki obsega fosforamidni derivat 5-fluoro-2'-deoksiuridina za uporabo pri zdravljenju raka
|
|
US9085599B2
(en)
|
2011-03-16 |
2015-07-21 |
Enanta Pharmaceuticals, Inc. |
2′allene-substituted nucleoside derivatives
|
|
JP2014514295A
(ja)
|
2011-03-31 |
2014-06-19 |
アイディニックス ファーマシューティカルズ インコーポレイテッド |
ウイルス感染の治療のための化合物および薬学的組成物
|
|
EP2697241B1
(en)
|
2011-04-13 |
2019-06-12 |
Gilead Sciences, Inc. |
1'-substituted pyrimidine n-nucleoside analogs for antiviral treatment
|
|
CN103582420B
(zh)
|
2011-04-13 |
2016-10-19 |
默沙东公司 |
2’-取代的核苷衍生物和使用其治疗病毒病的方法
|
|
US9156872B2
(en)
|
2011-04-13 |
2015-10-13 |
Merck Sharp & Dohme Corp. |
2′-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
RU2013125713A
(ru)
|
2011-05-19 |
2015-06-27 |
Рфс Фарма, Ллк |
Пуринмонофосфатные пролекарства для лечения вирусных инфекций
|
|
KR20140050661A
(ko)
*
|
2011-07-12 |
2014-04-29 |
벤더르빌트 유니버시티 |
감마-케토알데하이드 소거제로 염증 및 고혈압을 치료하기 위한 방법
|
|
WO2013009737A1
(en)
|
2011-07-13 |
2013-01-17 |
Merck Sharp & Dohme Corp. |
5'-substituted nucleoside analogs and methods of use thereof for the treatment of viral diseases
|
|
EP2739154B1
(en)
|
2011-08-01 |
2018-06-27 |
MBC Pharma, Inc. |
Vitamin b6 derivatives of nucleotides, acyclonucleotides and acyclonucleoside phosphonates
|
|
WO2013039920A1
(en)
|
2011-09-12 |
2013-03-21 |
Idenix Pharmaceuticals, Inc. |
Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections
|
|
WO2013039855A1
(en)
|
2011-09-12 |
2013-03-21 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
WO2013044030A1
(en)
|
2011-09-23 |
2013-03-28 |
Enanta Pharmaceuticals, Inc. |
2'-chloroacetylenyl substituted nucleoside derivatives
|
|
EP2768838A1
(en)
|
2011-10-14 |
2014-08-27 |
IDENIX Pharmaceuticals, Inc. |
Substituted 3',5'-cyclic phosphates of purine nucleotide compounds and pharmaceutical compositions for the treatment of viral infections
|
|
EP2768514B8
(en)
|
2011-10-19 |
2019-06-19 |
Mercator Medsystems, Inc. |
Localized modulation of tissues and cells to enhance therapeutic effects including renal denervation
|
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
|
US20130244966A1
(en)
|
2011-12-12 |
2013-09-19 |
Catabasis Pharmaceuticals, Inc. |
Fatty acid antiviral conjugates and their uses
|
|
GB2497580A
(en)
|
2011-12-16 |
2013-06-19 |
Intercede Ltd |
Data transmission using a plurality of barcodes displayed in a loop
|
|
AU2012358804B2
(en)
|
2011-12-22 |
2018-04-19 |
Alios Biopharma, Inc. |
Substituted phosphorothioate nucleotide analogs
|
|
EA201491525A1
(ru)
|
2012-02-14 |
2014-12-30 |
Юниверсити Оф Джорджиа Рисерч Фаундэйшн, Инк. |
Спиро[2.4]гептаны для лечения инфекций, вызванных flaviviridae
|
|
HUE034936T2
(hu)
|
2012-02-27 |
2018-03-28 |
Bristol Myers Squibb Co |
N-(5S,6S,9R)-5-amino-6-(2,3-difluorfenil)-6,7,8,9-tetrahidro-5H-ciklohepta[B-]piridin-9-il-4- (2-oxo-2,3-dihidro-1H-imidazo[4,5-B]piridin-1-IL)piperidin-1-karboxilát, hemiszulfát só
|
|
WO2013142159A1
(en)
|
2012-03-21 |
2013-09-26 |
Alios Biopharma, Inc. |
Pharmaceutical combinations comprising a thionucleotide analog
|
|
HK1203513A1
(en)
|
2012-03-21 |
2015-10-30 |
艾丽奥斯生物制药有限公司 |
Methods of preparing substituted nucleotide analogs
|
|
US9012427B2
(en)
|
2012-03-22 |
2015-04-21 |
Alios Biopharma, Inc. |
Pharmaceutical combinations comprising a thionucleotide analog
|
|
US20150057243A1
(en)
|
2012-04-02 |
2015-02-26 |
Northern University |
Compositions and Methods for the Inhibition of Methyltransferases
|
|
US8846638B2
(en)
|
2012-05-17 |
2014-09-30 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic nucleoside phosphoramidate derivatives
|
|
CN103421068A
(zh)
*
|
2012-05-17 |
2013-12-04 |
世方药业（杭州）有限公司 |
具有抗病毒活性的杂芳基磷酰胺类化合物
|
|
HK1203514A1
(en)
|
2012-05-22 |
2015-10-30 |
Idenix Pharmaceuticals Llc |
D-amino acid compounds for liver disease
|
|
EP2852604B1
(en)
|
2012-05-22 |
2017-04-12 |
Idenix Pharmaceuticals LLC |
3',5'-cyclic phosphoramidate prodrugs for hcv infection
|
|
CN104640444B
(zh)
|
2012-06-16 |
2016-12-14 |
河南美泰宝生物制药有限公司 |
双肝脏靶向氨基磷酸酯和氨基膦酸酯前药
|
|
EP2870169A1
(en)
|
2012-07-03 |
2015-05-13 |
Bristol-Myers Squibb Company |
Process for preparing diastereomerically enriched phosphoramidate derivatives of nucleoside compounds for treatment of viral infections
|
|
US9326991B2
(en)
|
2012-09-14 |
2016-05-03 |
Ligand Pharmaceuticals, Inc. |
Nucleotide prodrug compounds and use
|
|
WO2014047117A1
(en)
|
2012-09-18 |
2014-03-27 |
Bristol-Myers Squibb Company |
Process for preparing phosphoramidate derivatives of nucleoside compounds for treatment of viral infections
|
|
WO2014052638A1
(en)
|
2012-09-27 |
2014-04-03 |
Idenix Pharmaceuticals, Inc. |
Esters and malonates of sate prodrugs
|
|
MX353422B
(es)
|
2012-10-08 |
2018-01-12 |
Idenix Pharmaceuticals Llc |
Análogos de 2'-cloronucleósido para infección por vhc.
|
|
US20140112886A1
(en)
|
2012-10-19 |
2014-04-24 |
Idenix Pharmaceuticals, Inc. |
Dinucleotide compounds for hcv infection
|
|
BR112015009636A8
(pt)
|
2012-10-29 |
2018-04-17 |
Cocrystal Pharma Inc |
composto, métodos para o tratamento de um hospedeiro infectado, métodos para a prevenção de uma infecção, métodos para a redução da atividade biológica de uma infecção e uso de um composto
|
|
EA028871B1
(ru)
|
2012-11-16 |
2018-01-31 |
Юниверсити Колледж Кардифф Консалтантс Лимитед |
Способ получения химических соединений
|
|
GB201220843D0
(en)
|
2012-11-20 |
2013-01-02 |
Univ College Cork Nat Univ Ie |
Compound
|
|
US20140205566A1
(en)
|
2012-11-30 |
2014-07-24 |
Novartis Ag |
Cyclic nucleuoside derivatives and uses thereof
|
|
WO2014099941A1
(en)
*
|
2012-12-19 |
2014-06-26 |
Idenix Pharmaceuticals, Inc. |
4'-fluoro nucleosides for the treatment of hcv
|
|
US9598457B2
(en)
|
2012-12-21 |
2017-03-21 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
GEP201706757B
(en)
|
2012-12-21 |
2017-10-25 |
Alios Biopharma Inc |
Substituted nucleosides, nucleotides and analogs thereof
|
|
SG11201506021XA
(en)
|
2013-01-31 |
2015-08-28 |
Gilead Pharmasset Llc |
Combination formulation of two antiviral compounds
|
|
WO2014124430A1
(en)
|
2013-02-11 |
2014-08-14 |
Emory University |
Nucleotide and nucleoside therapeutic compositions and uses related thereto
|
|
WO2014137930A1
(en)
|
2013-03-04 |
2014-09-12 |
Idenix Pharmaceuticals, Inc. |
Thiophosphate nucleosides for the treatment of hcv
|
|
US9963480B2
(en)
*
|
2013-03-08 |
2018-05-08 |
Nanjing Sanhome Pharmaceutical Co., Ltd. |
Nucleoside phosphoramidate compound and use thereof
|
|
US9187515B2
(en)
|
2013-04-01 |
2015-11-17 |
Idenix Pharmaceuticals Llc |
2′,4′-fluoro nucleosides for the treatment of HCV
|
|
AU2014250762A1
(en)
|
2013-04-12 |
2015-10-29 |
Achillion Pharmaceuticals, Inc. |
Highly active nucleoside derivative for the treatment of HCV
|
|
CN103435672A
(zh)
|
2013-04-25 |
2013-12-11 |
刘沛 |
含有取代苄基的新型核苷磷酸酯前药的结构与合成
|
|
AU2014302711A1
(en)
|
2013-06-26 |
2015-12-10 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
AU2014284455A1
(en)
|
2013-07-02 |
2016-01-21 |
Abbvie Inc. |
Methods for treating HCV
|
|
EP3043803B1
(en)
|
2013-09-11 |
2022-04-27 |
Emory University |
Nucleotide and nucleoside compositions and their uses
|
|
CN105829333A
(zh)
|
2013-10-11 |
2016-08-03 |
艾丽奥斯生物制药有限公司 |
取代的核苷、核苷酸及其类似物
|
|
US8889701B1
(en)
|
2013-10-11 |
2014-11-18 |
Alla Chem, Llc |
Substituted (S)-(2R,3R,5R)-3-hydroxy-(5-pyrimidin-1-yl)tetrahydrofuran-2-ylmethyl aryl phosphoramidate
|
|
WO2015061683A1
(en)
|
2013-10-25 |
2015-04-30 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate and d-alanine thiophosphoramidate pronucleotides of nucleoside compounds useful for the treatment of hcv
|
|
WO2015066370A1
(en)
*
|
2013-11-01 |
2015-05-07 |
Idenix Pharmaceuticals, Inc. |
D-alanine phosphoramidate pronucleotides of 2'-methyl 2'-fluoro guanosine nucleoside compounds for the treatment of hcv
|
|
CN105934438A
(zh)
|
2013-11-27 |
2016-09-07 |
艾登尼克斯药业有限公司 |
用于治疗肝癌的核苷酸
|
|
US20150150897A1
(en)
|
2013-12-02 |
2015-06-04 |
Gilead Pharmasset Llc |
Methods of treating hepatitis c virus infection in subjects with cirrhosis
|
|
WO2015095305A1
(en)
|
2013-12-17 |
2015-06-25 |
Idenix Pharmaceuticals, Inc. |
Production of cyclic phosphate, phosphoramidate, thiophosphate, and phosphonate nucleoside compounds
|
|
US20170022242A1
(en)
|
2014-04-17 |
2017-01-26 |
Katholieke Universiteit Leuven, KU LEUVEN R&D |
Novel antiviral and antitumoral compounds
|
|
EA201692535A1
(ru)
|
2014-06-24 |
2017-05-31 |
Элиос Биофарма, Инк. |
Замещенные нуклеозиды, нуклеотиды и их аналоги
|
|
MA40031A
(fr)
|
2014-06-24 |
2015-12-30 |
Alios Biopharma Inc |
Nucléosides substitués, nucléotides et analogues de ceux-ci
|
|
EP3194414A1
(en)
|
2014-09-15 |
2017-07-26 |
Medivir Ab |
Methods for the preparation of diastereomerically pure phosphoramidate prodrugs
|
|
WO2016066582A1
(en)
|
2014-10-28 |
2016-05-06 |
Bci Pharma |
Nucleoside kinase inhibitors
|
|
CN105646629A
(zh)
|
2014-11-25 |
2016-06-08 |
广州市恒诺康医药科技有限公司 |
L-核苷类化合物及其应用
|
|
MA41213A
(fr)
|
2014-12-19 |
2017-10-24 |
Alios Biopharma Inc |
Nucléosides substitués, nucléotides et analogues de ceux-ci
|
|
MA41441A
(fr)
|
2014-12-19 |
2017-12-12 |
Alios Biopharma Inc |
Nucléosides substitués, nucléotides et analogues de ceux-ci
|
|
MX2017011386A
(es)
|
2015-03-06 |
2018-04-26 |
Atea Pharmaceuticals Inc |
NUCLEÓTIDOS DE PURINA ß-D-2'-DEOXI-2'A-FLUORO-2'-ß-C-SUSTITUIDOS-2 - MODIFICADOS-N6- SUSTITUIDOS PARA EL TRATAMIENTO DEL VIRUS DE LA HEPATITIS C.
|
|
WO2016145142A1
(en)
|
2015-03-10 |
2016-09-15 |
Emory University |
Nucleotide and nucleoside therapeutics compositions and uses related thereto
|
|
CN106188192B
(zh)
|
2015-04-29 |
2019-09-10 |
刘沛 |
含d-氨基酸酯的核苷氨基磷酸/膦酸酯衍生物及其医药用途
|
|
CN106366146A
(zh)
|
2015-07-13 |
2017-02-01 |
中科云和（北京）生物医药科技有限公司 |
2’-双烷基取代的核苷类似物及用途
|
|
KR102000100B1
(ko)
*
|
2016-03-23 |
2019-07-16 |
주식회사 엘지화학 |
비수전해액 첨가제, 이를 포함하는 리튬 이차전지용 비수전해액 및 리튬 이차전지
|
|
WO2018013937A1
(en)
|
2016-07-14 |
2018-01-18 |
Atea Pharmaceuticals, Inc. |
Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection
|
|
RS62943B1
(sr)
|
2016-09-07 |
2022-03-31 |
Atea Pharmaceuticals Inc |
2’-supstituisani-n6-supstituisani purinski nukleotidi za lečenje bolesti izazvanih rnk virusima
|
|
TW202012001A
(zh)
|
2018-04-10 |
2020-04-01 |
美商亞堤製藥公司 |
C型肝炎病毒(hcv)感染硬化之患者的治療
|