JP2017531619A5 - - Google Patents
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- Publication number
- JP2017531619A5 JP2017531619A5 JP2017513061A JP2017513061A JP2017531619A5 JP 2017531619 A5 JP2017531619 A5 JP 2017531619A5 JP 2017513061 A JP2017513061 A JP 2017513061A JP 2017513061 A JP2017513061 A JP 2017513061A JP 2017531619 A5 JP2017531619 A5 JP 2017531619A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- compound
- polymorph
- stereoisomer
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14187374.5 | 2014-10-01 | ||
| EP14187374 | 2014-10-01 | ||
| EP15159164 | 2015-03-16 | ||
| EP15159164.1 | 2015-03-16 | ||
| PCT/EP2015/072551 WO2016050841A1 (en) | 2014-10-01 | 2015-09-30 | Mono- or di-substituted indole derivatives as dengue viral replication inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017531619A JP2017531619A (ja) | 2017-10-26 |
| JP2017531619A5 true JP2017531619A5 (enExample) | 2018-11-08 |
| JP6732736B2 JP6732736B2 (ja) | 2020-07-29 |
Family
ID=54199687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017513061A Active JP6732736B2 (ja) | 2014-10-01 | 2015-09-30 | デングウィルス複製阻害剤としての一または二置換インドール誘導体 |
Country Status (32)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201116559D0 (en) | 2011-09-26 | 2011-11-09 | Univ Leuven Kath | Novel viral replication inhibitors |
| GB201305376D0 (en) | 2013-03-25 | 2013-05-08 | Univ Leuven Kath | Novel viral replication inhibitors |
| JP6662865B2 (ja) | 2014-10-01 | 2020-03-11 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | ボロン酸誘導体 |
| PL3201177T3 (pl) * | 2014-10-01 | 2019-05-31 | Janssen Pharmaceuticals Inc | Mono- lub di-podstawione indole jako inhibitory replikacji wirusa dengi |
| US9453018B2 (en) | 2014-10-01 | 2016-09-27 | Bristol-Myers Squibb Company | Pyrimidinones as factor XIa inhibitors |
| JOP20160086B1 (ar) * | 2015-05-08 | 2021-08-17 | 2 Katholieke Univ Leuven Ku Leuven Research And Development | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JO3633B1 (ar) * | 2015-09-16 | 2020-08-27 | Katholieke Univ Leuven Ku Leuven Research & Development | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JOP20160198B1 (ar) | 2015-09-16 | 2022-03-14 | Janssen Pharmaceuticals Inc | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| CR20180496A (es) | 2016-03-31 | 2018-12-06 | Univ Leuven Kath | Derivados de indolina sustituidos como inhibidores de la replicación vírica de dengue |
| WO2017167950A1 (en) | 2016-03-31 | 2017-10-05 | Janssen Pharmaceuticals, Inc. | Substituted indole derivatives as dengue viral replication inhibitors |
| CN109069482B (zh) * | 2016-04-01 | 2022-04-05 | 杨森制药公司 | 作为登革热病毒复制抑制剂的经取代的吲哚化合物衍生物 |
| JOP20170069B1 (ar) * | 2016-04-01 | 2021-08-17 | 1 Janssen Pharmaceuticals Inc | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JOP20180025B1 (ar) | 2017-03-31 | 2021-08-17 | Janssen Pharmaceuticals Inc | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JOP20180026A1 (ar) | 2017-03-31 | 2019-01-30 | Univ Leuven Kath | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| MX393586B (es) * | 2017-05-22 | 2025-03-24 | Janssen Pharmaceuticals Inc | Derivados de indolina sustituidos como inhibidores de la replicacion virica de dengue |
| PE20200342A1 (es) * | 2017-05-22 | 2020-02-14 | Janssen Pharmaceuticals Inc | Derivados de indolina sustituidos como inhibidores de la replicacion virica de dengue |
| CN121358711A (zh) * | 2023-06-05 | 2026-01-16 | 载度思生命科学有限公司 | 治疗病毒感染的新的化合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX336687B (es) * | 2009-06-30 | 2016-01-28 | Siga Technologies Inc | Tratamiento y prevencion de infecciones del virus del dengue. |
| GB201116559D0 (en) * | 2011-09-26 | 2011-11-09 | Univ Leuven Kath | Novel viral replication inhibitors |
| JOP20160086B1 (ar) * | 2015-05-08 | 2021-08-17 | 2 Katholieke Univ Leuven Ku Leuven Research And Development | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JOP20160198B1 (ar) * | 2015-09-16 | 2022-03-14 | Janssen Pharmaceuticals Inc | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
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2015
- 2015-09-30 EP EP15771136.7A patent/EP3201176B1/en active Active
- 2015-09-30 PL PL15771136T patent/PL3201176T3/pl unknown
- 2015-09-30 HR HRP20190199TT patent/HRP20190199T1/hr unknown
- 2015-09-30 SM SM20190162T patent/SMT201900162T1/it unknown
- 2015-09-30 TW TW104132008A patent/TWI681951B/zh not_active IP Right Cessation
- 2015-09-30 SI SI201530603T patent/SI3201176T1/sl unknown
- 2015-09-30 BR BR112017006299-2A patent/BR112017006299A2/pt not_active Application Discontinuation
- 2015-09-30 CA CA2959573A patent/CA2959573A1/en not_active Abandoned
- 2015-09-30 UA UAA201704215A patent/UA121119C2/uk unknown
- 2015-09-30 DK DK15771136.7T patent/DK3201176T3/en active
- 2015-09-30 AU AU2015326930A patent/AU2015326930B2/en not_active Expired - Fee Related
- 2015-09-30 ES ES15771136T patent/ES2714074T3/es active Active
- 2015-09-30 RS RS20190206A patent/RS58461B1/sr unknown
- 2015-09-30 KR KR1020177011122A patent/KR102478311B1/ko active Active
- 2015-09-30 CN CN201580053446.3A patent/CN107001264B/zh active Active
- 2015-09-30 ME MEP-2019-62A patent/ME03360B/me unknown
- 2015-09-30 WO PCT/EP2015/072551 patent/WO2016050841A1/en not_active Ceased
- 2015-09-30 SG SG11201702463YA patent/SG11201702463YA/en unknown
- 2015-09-30 LT LTEP15771136.7T patent/LT3201176T/lt unknown
- 2015-09-30 MX MX2017004299A patent/MX2017004299A/es unknown
- 2015-09-30 HU HUE15771136A patent/HUE041888T2/hu unknown
- 2015-09-30 PT PT15771136T patent/PT3201176T/pt unknown
- 2015-09-30 EA EA201790758A patent/EA032546B1/ru not_active IP Right Cessation
- 2015-09-30 JP JP2017513061A patent/JP6732736B2/ja active Active
- 2015-09-30 US US15/515,574 patent/US9944598B2/en active Active
- 2015-09-30 MA MA40768A patent/MA40768B1/fr unknown
- 2015-10-01 UY UY0001036340A patent/UY36340A/es unknown
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2017
- 2017-03-27 IL IL251396A patent/IL251396A0/en unknown
- 2017-03-27 PH PH12017500571A patent/PH12017500571A1/en unknown
- 2017-03-31 ZA ZA2017/02301A patent/ZA201702301B/en unknown
- 2017-03-31 CL CL2017000782A patent/CL2017000782A1/es unknown
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2019
- 2019-03-01 CY CY20191100257T patent/CY1121874T1/el unknown