JP2017523225A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017523225A5 JP2017523225A5 JP2017506964A JP2017506964A JP2017523225A5 JP 2017523225 A5 JP2017523225 A5 JP 2017523225A5 JP 2017506964 A JP2017506964 A JP 2017506964A JP 2017506964 A JP2017506964 A JP 2017506964A JP 2017523225 A5 JP2017523225 A5 JP 2017523225A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- substituted
- carboxylic acid
- formula
- heterocycle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14180331.2 | 2014-08-08 | ||
| EP14180331 | 2014-08-08 | ||
| PCT/EP2015/068257 WO2016020526A1 (en) | 2014-08-08 | 2015-08-07 | Indoles for use in influenza virus infection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017523225A JP2017523225A (ja) | 2017-08-17 |
| JP2017523225A5 true JP2017523225A5 (enExample) | 2019-08-22 |
| JP6577570B2 JP6577570B2 (ja) | 2019-09-18 |
Family
ID=51298610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017506964A Expired - Fee Related JP6577570B2 (ja) | 2014-08-08 | 2015-08-07 | インフルエンザウイルス感染に使用するためのインドール類 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US10597390B2 (enExample) |
| EP (1) | EP3177609A1 (enExample) |
| JP (1) | JP6577570B2 (enExample) |
| KR (1) | KR102488479B1 (enExample) |
| CN (1) | CN106573920B (enExample) |
| AU (1) | AU2015298876B2 (enExample) |
| BR (1) | BR112017002370B1 (enExample) |
| CA (1) | CA2954751C (enExample) |
| CL (1) | CL2017000309A1 (enExample) |
| EA (1) | EA201790266A1 (enExample) |
| IL (1) | IL250408B (enExample) |
| MA (1) | MA40547A (enExample) |
| MX (1) | MX381488B (enExample) |
| PH (1) | PH12017500207A1 (enExample) |
| SG (1) | SG11201700956VA (enExample) |
| UA (1) | UA124609C2 (enExample) |
| WO (1) | WO2016020526A1 (enExample) |
| ZA (1) | ZA201700952B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104151312B (zh) | 2009-06-17 | 2016-06-15 | 沃泰克斯药物股份有限公司 | 流感病毒复制抑制剂 |
| UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| AU2015298876B2 (en) | 2014-08-08 | 2020-02-13 | Janssen Sciences Ireland Uc | Indoles for use in influenza virus infection |
| EP3294717B1 (en) | 2015-05-13 | 2020-07-29 | Vertex Pharmaceuticals Inc. | Methods of preparing inhibitors of influenza viruses replication |
| WO2016183120A1 (en) | 2015-05-13 | 2016-11-17 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| CN106854205B (zh) | 2015-12-09 | 2019-07-09 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其使用方法和用途 |
| CA3007758A1 (en) * | 2016-01-07 | 2017-07-13 | Janssen Sciences Ireland Uc | Functionalized pentanoic acids for use in influenza viral infections |
| WO2017133670A1 (en) * | 2016-02-05 | 2017-08-10 | Savira Pharmaceuticals Gmbh | Pyridine and pyrimidine derivatives and their use in treatment, amelioration or prevention of influenza |
| WO2018033082A1 (en) * | 2016-08-16 | 2018-02-22 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication, application methods and uses thereof |
| US10647693B2 (en) | 2016-08-30 | 2020-05-12 | North & South Brother Pharmacy Investment Company Limited | Inhibitors of influenza virus replication, application methods and uses thereof |
| SG11201901894TA (en) * | 2016-09-05 | 2019-04-29 | Guangdong Raynovent Biotech Co Ltd | Anti-influenza virus pyrimidine derivatives |
| WO2018108125A1 (en) | 2016-12-15 | 2018-06-21 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
| EP4306166A3 (en) | 2016-12-23 | 2024-06-26 | Aquinnah Pharmaceuticals Inc. | Compounds, compositions and methods of use |
| WO2018127096A1 (en) | 2017-01-05 | 2018-07-12 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
| CN110446711B (zh) | 2017-03-02 | 2022-02-15 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其用途 |
| CN108727369B (zh) * | 2017-04-25 | 2023-06-09 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其用途 |
| CA3092315C (en) * | 2018-03-05 | 2023-08-29 | Jian Xiong | Crystal form and salt form of pyridopyrazole compound and preparation method therefor |
| JP7450017B2 (ja) | 2019-07-22 | 2024-03-14 | 広東衆生睿創生物科技有限公司 | ピリミジン誘導体の優位な塩形およびその結晶形 |
| CN113045475A (zh) * | 2019-12-27 | 2021-06-29 | 上海泓博智源医药股份有限公司 | 一种5-溴-7-甲基吲哚的制备方法 |
| TW202216720A (zh) * | 2020-07-20 | 2022-05-01 | 美商尼道生物科學公司 | 作為雄激素受體調節劑的吲哚化合物 |
| US20240010643A1 (en) * | 2020-09-18 | 2024-01-11 | Sunshine Lake Pharma Co., Ltd. | Preparation method of substituted pyrimidine piperazine compounds |
| KR20250103814A (ko) * | 2022-10-12 | 2025-07-07 | 메이즈 테라퓨틱스, 인코퍼레이티드 | 용질 담체 계열 6a 구성원 19(slc6a19)의 억제제 및 이의 사용 방법 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1730146B1 (en) | 2004-03-30 | 2011-05-04 | Vertex Pharmaceuticals Incorporated | Azaindoles useful as inhibitors of jak and other protein kinases |
| AU2007207533B8 (en) | 2006-01-17 | 2012-06-28 | Vertex Pharmaceuticals Incorporated | Azaindoles useful as inhibitors of Janus kinases |
| CN104151312B (zh) * | 2009-06-17 | 2016-06-15 | 沃泰克斯药物股份有限公司 | 流感病毒复制抑制剂 |
| ES2602972T3 (es) * | 2010-09-08 | 2017-02-23 | Glaxosmithkline Intellectual Property Development Limited | Derivados de indazol para su uso en el tratamiento de infección por virus de la gripe |
| MX2013006840A (es) | 2010-12-16 | 2014-01-31 | Vertex Pharma | Inhibidores de la replicacion de los virus de la influenza. |
| MX2013006836A (es) | 2010-12-16 | 2013-09-26 | Vertex Pharma | Inhibidores de la replicacion de los virus de la influenza. |
| UA118010C2 (uk) * | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| BR112014004569A2 (pt) | 2011-09-01 | 2017-06-13 | F. Hoffmann-La Roche Ag | composto da fórmula i, métodos para tratar condição inflamatória, artrite reumatoide, asma e distúrbio imune, composição farmacêutica e uso do composto |
| EP2858984A1 (en) * | 2012-06-08 | 2015-04-15 | Vertex Pharmaceuticals Inc. | Inhibitors of influenza viruses replication |
| HUE044667T2 (hu) | 2013-11-13 | 2019-11-28 | Vertex Pharma | Influenza vírus replikáció inhibitorok |
| UY36249A (es) | 2014-08-08 | 2016-01-29 | Bayer Cropscience Ag | Compuestos sustituidos con halógeno novedosos |
| AU2015298876B2 (en) | 2014-08-08 | 2020-02-13 | Janssen Sciences Ireland Uc | Indoles for use in influenza virus infection |
| AR101448A1 (es) | 2014-08-08 | 2016-12-21 | Bayer Cropscience Ag | Compuestos sustituidos por halógeno |
| CN104592038A (zh) | 2015-01-12 | 2015-05-06 | 烟台万润精细化工股份有限公司 | 一种5,5-二甲基-1,3-环己二胺的制备方法 |
-
2015
- 2015-08-07 AU AU2015298876A patent/AU2015298876B2/en not_active Ceased
- 2015-08-07 MA MA040547A patent/MA40547A/fr unknown
- 2015-08-07 CN CN201580042406.9A patent/CN106573920B/zh not_active Expired - Fee Related
- 2015-08-07 US US15/501,730 patent/US10597390B2/en not_active Expired - Fee Related
- 2015-08-07 EP EP15750365.7A patent/EP3177609A1/en not_active Withdrawn
- 2015-08-07 EA EA201790266A patent/EA201790266A1/ru unknown
- 2015-08-07 WO PCT/EP2015/068257 patent/WO2016020526A1/en not_active Ceased
- 2015-08-07 KR KR1020177005979A patent/KR102488479B1/ko active Active
- 2015-08-07 UA UAA201702154A patent/UA124609C2/uk unknown
- 2015-08-07 SG SG11201700956VA patent/SG11201700956VA/en unknown
- 2015-08-07 JP JP2017506964A patent/JP6577570B2/ja not_active Expired - Fee Related
- 2015-08-07 BR BR112017002370-9A patent/BR112017002370B1/pt not_active IP Right Cessation
- 2015-08-07 MX MX2017001752A patent/MX381488B/es unknown
- 2015-08-07 CA CA2954751A patent/CA2954751C/en active Active
-
2017
- 2017-02-02 IL IL250408A patent/IL250408B/en active IP Right Grant
- 2017-02-02 PH PH12017500207A patent/PH12017500207A1/en unknown
- 2017-02-07 ZA ZA2017/00952A patent/ZA201700952B/en unknown
- 2017-02-07 CL CL2017000309A patent/CL2017000309A1/es unknown