JP6577570B2 - インフルエンザウイルス感染に使用するためのインドール類 - Google Patents
インフルエンザウイルス感染に使用するためのインドール類 Download PDFInfo
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- JP6577570B2 JP6577570B2 JP2017506964A JP2017506964A JP6577570B2 JP 6577570 B2 JP6577570 B2 JP 6577570B2 JP 2017506964 A JP2017506964 A JP 2017506964A JP 2017506964 A JP2017506964 A JP 2017506964A JP 6577570 B2 JP6577570 B2 JP 6577570B2
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- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| PCT/EP2015/068257 WO2016020526A1 (en) | 2014-08-08 | 2015-08-07 | Indoles for use in influenza virus infection |
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| GEP20207129B (en) | 2009-06-17 | 2020-07-10 | Vertex Pharma | Inhibitors of influenza viruses replication |
| UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| EA201790266A1 (ru) | 2014-08-08 | 2017-06-30 | Янссен Сайенсиз Айрлэнд Юси | Индолы для применения при инфекции, вызванной вирусом гриппа |
| EP3294717B1 (en) | 2015-05-13 | 2020-07-29 | Vertex Pharmaceuticals Inc. | Methods of preparing inhibitors of influenza viruses replication |
| WO2016183120A1 (en) | 2015-05-13 | 2016-11-17 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| EP3362451B1 (en) | 2015-12-09 | 2023-04-12 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication, application methods and uses thereof |
| WO2017118680A1 (en) * | 2016-01-07 | 2017-07-13 | Janssen Sciences Ireland Uc | Functionalized pentanoic acids for use in influenza viral infections |
| WO2017133670A1 (en) * | 2016-02-05 | 2017-08-10 | Savira Pharmaceuticals Gmbh | Pyridine and pyrimidine derivatives and their use in treatment, amelioration or prevention of influenza |
| CN107759571B (zh) * | 2016-08-16 | 2021-03-02 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其使用方法和用途 |
| US10647693B2 (en) | 2016-08-30 | 2020-05-12 | North & South Brother Pharmacy Investment Company Limited | Inhibitors of influenza virus replication, application methods and uses thereof |
| MX394277B (es) * | 2016-09-05 | 2025-03-24 | Guangdong Raynovent Biotech Co Ltd | Derivados de pirimidina contra virus de la influenza |
| CA3045371C (en) | 2016-12-15 | 2024-05-14 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
| EP4306166A3 (en) * | 2016-12-23 | 2024-06-26 | Aquinnah Pharmaceuticals Inc. | Compounds, compositions and methods of use |
| WO2018127096A1 (en) | 2017-01-05 | 2018-07-12 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
| US10927118B2 (en) | 2017-03-02 | 2021-02-23 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
| CN108727369B (zh) * | 2017-04-25 | 2023-06-09 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其用途 |
| NZ767352A (en) * | 2018-03-05 | 2023-05-26 | Guangdong Raynovent Biotech Co Ltd | Crystal form and salt form of pyridopyrazole compound and preparation method therefor |
| CN114127068B (zh) | 2019-07-22 | 2024-05-28 | 广东众生睿创生物科技有限公司 | 嘧啶衍生物的优势盐型及其晶型 |
| CN113045475A (zh) * | 2019-12-27 | 2021-06-29 | 上海泓博智源医药股份有限公司 | 一种5-溴-7-甲基吲哚的制备方法 |
| CA3185649A1 (en) | 2020-07-20 | 2022-01-27 | Bakary-Barry Toure | Indole compounds as androgen receptor modulators |
| EP4214201A4 (en) * | 2020-09-18 | 2024-10-09 | Sunshine Lake Pharma Co., Ltd. | PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIMIDINE PIPERAZINE COMPOUNDS |
| AU2023361174A1 (en) * | 2022-10-12 | 2025-05-01 | Maze Therapeutics, Inc. | Inhibitors of solute carrier family 6a member 19 (slc6a19) and methods of use thereof |
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| ES2364340T3 (es) | 2004-03-30 | 2011-08-31 | Vertex Pharmaceuticals Incorporated | Azaindoles útiles como inhibidores de jak y otras proteína quinasas. |
| NZ592968A (en) | 2006-01-17 | 2012-08-31 | Vertex Pharma | Azaindoles substituted with either triazine or pyrimidine useful as inhibitors of janus kinases consisting of JAK1, JAK2, JAK3, and TYK2 |
| GEP20207129B (en) * | 2009-06-17 | 2020-07-10 | Vertex Pharma | Inhibitors of influenza viruses replication |
| EP2613781B1 (en) | 2010-09-08 | 2016-08-24 | GlaxoSmithKline Intellectual Property Development Limited | Indazole derivatives for use in the treatment of influenza virus infection |
| AU2011343647A1 (en) * | 2010-12-16 | 2013-05-02 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| RU2013132681A (ru) | 2010-12-16 | 2015-01-27 | Вертекс Фармасьютикалз Инкорпорейтед | Ингибиторы репликации вирусов гриппа |
| UA118010C2 (uk) * | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| WO2013030138A1 (en) | 2011-09-01 | 2013-03-07 | F. Hoffmann-La Roche Ag | Pyrrolopyrazine kinase inhibitors |
| WO2013184985A1 (en) | 2012-06-08 | 2013-12-12 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| PT3068776T (pt) | 2013-11-13 | 2019-08-26 | Vertex Pharma | Inibidores da replicação de vírus da gripe |
| AR101401A1 (es) | 2014-08-08 | 2016-12-14 | Bayer Cropscience Ag | Derivados de bipirazol, sustituidos con halógeno |
| UY36255A (es) | 2014-08-08 | 2016-01-29 | Bayer Cropscience Ag | Compuestos sustituidos por halógeno novedosos |
| EA201790266A1 (ru) | 2014-08-08 | 2017-06-30 | Янссен Сайенсиз Айрлэнд Юси | Индолы для применения при инфекции, вызванной вирусом гриппа |
| CN104592038A (zh) | 2015-01-12 | 2015-05-06 | 烟台万润精细化工股份有限公司 | 一种5,5-二甲基-1,3-环己二胺的制备方法 |
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- 2015-08-07 CA CA2954751A patent/CA2954751C/en active Active
- 2015-08-07 MA MA040547A patent/MA40547A/fr unknown
- 2015-08-07 MX MX2017001752A patent/MX381488B/es unknown
- 2015-08-07 JP JP2017506964A patent/JP6577570B2/ja not_active Expired - Fee Related
- 2015-08-07 AU AU2015298876A patent/AU2015298876B2/en not_active Ceased
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| CA2954751C (en) | 2023-01-17 |
| EP3177609A1 (en) | 2017-06-14 |
| CL2017000309A1 (es) | 2017-08-18 |
| CN106573920A (zh) | 2017-04-19 |
| KR102488479B1 (ko) | 2023-01-12 |
| WO2016020526A1 (en) | 2016-02-11 |
| SG11201700956VA (en) | 2017-03-30 |
| AU2015298876A1 (en) | 2017-02-02 |
| AU2015298876B2 (en) | 2020-02-13 |
| PH12017500207B1 (en) | 2017-07-10 |
| US20170226102A1 (en) | 2017-08-10 |
| IL250408A0 (en) | 2017-03-30 |
| UA124609C2 (uk) | 2021-10-20 |
| BR112017002370A2 (pt) | 2017-12-05 |
| US10597390B2 (en) | 2020-03-24 |
| EA201790266A1 (ru) | 2017-06-30 |
| MX2017001752A (es) | 2018-02-08 |
| PH12017500207A1 (en) | 2017-07-10 |
| IL250408B (en) | 2020-08-31 |
| ZA201700952B (en) | 2018-12-19 |
| CA2954751A1 (en) | 2016-02-11 |
| MA40547A (fr) | 2017-06-14 |
| CN106573920B (zh) | 2020-11-10 |
| BR112017002370B1 (pt) | 2022-11-22 |
| JP2017523225A (ja) | 2017-08-17 |
| MX381488B (es) | 2025-03-12 |
| KR20170039275A (ko) | 2017-04-10 |
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