JP6577570B2 - インフルエンザウイルス感染に使用するためのインドール類 - Google Patents
インフルエンザウイルス感染に使用するためのインドール類 Download PDFInfo
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- JP6577570B2 JP6577570B2 JP2017506964A JP2017506964A JP6577570B2 JP 6577570 B2 JP6577570 B2 JP 6577570B2 JP 2017506964 A JP2017506964 A JP 2017506964A JP 2017506964 A JP2017506964 A JP 2017506964A JP 6577570 B2 JP6577570 B2 JP 6577570B2
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- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
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- Virology (AREA)
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- Molecular Biology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
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| PCT/EP2015/068257 WO2016020526A1 (en) | 2014-08-08 | 2015-08-07 | Indoles for use in influenza virus infection |
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| WO (1) | WO2016020526A1 (enExample) |
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Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
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| TWI483941B (zh) | 2009-06-17 | 2015-05-11 | Vertex Pharma | 流感病毒複製之抑制劑 |
| UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| SG11201700956VA (en) | 2014-08-08 | 2017-03-30 | Janssen Sciences Ireland Uc | Indoles for use in influenza virus infection |
| EP3294717B1 (en) | 2015-05-13 | 2020-07-29 | Vertex Pharmaceuticals Inc. | Methods of preparing inhibitors of influenza viruses replication |
| WO2016183120A1 (en) | 2015-05-13 | 2016-11-17 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| AU2016368317B2 (en) | 2015-12-09 | 2019-05-23 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication, application methods and uses thereof |
| SI3400225T1 (sl) * | 2016-01-07 | 2022-01-31 | Janssen Sciences Ireland Unlimited Company | Pentanojske kisline substituirane s pirolo-(2-3,b)pirimidin-piridini za zdravljenje okužb z virusom gripe |
| WO2017133670A1 (en) * | 2016-02-05 | 2017-08-10 | Savira Pharmaceuticals Gmbh | Pyridine and pyrimidine derivatives and their use in treatment, amelioration or prevention of influenza |
| US10501444B2 (en) | 2016-08-16 | 2019-12-10 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication, application methods and uses thereof |
| CN109641868B (zh) * | 2016-08-30 | 2021-12-03 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其使用方法和用途 |
| CA3035680C (en) * | 2016-09-05 | 2023-05-02 | Jian Xiong | Anti-influenza virus pyrimidine derivatives |
| AU2017376541B2 (en) | 2016-12-15 | 2021-08-05 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
| CA3047404A1 (en) | 2016-12-23 | 2018-06-28 | Aquinnah Pharmaceuticals, Inc. | Compounds, compositions and methods of use |
| CN108276401B (zh) | 2017-01-05 | 2020-12-22 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其用途 |
| US10927118B2 (en) | 2017-03-02 | 2021-02-23 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
| CN108727369B (zh) * | 2017-04-25 | 2023-06-09 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其用途 |
| NZ767352A (en) * | 2018-03-05 | 2023-05-26 | Guangdong Raynovent Biotech Co Ltd | Crystal form and salt form of pyridopyrazole compound and preparation method therefor |
| EP3992192A4 (en) * | 2019-07-22 | 2022-08-17 | Guangdong Raynovent Biotech Co., Ltd. | DOMINANT SALT FORMS OF PYRIMIDINE DERIVATIVES AND CRYSTAL FORMS THEREOF |
| CN113045475A (zh) * | 2019-12-27 | 2021-06-29 | 上海泓博智源医药股份有限公司 | 一种5-溴-7-甲基吲哚的制备方法 |
| IL299989A (en) * | 2020-07-20 | 2023-03-01 | Nido Biosciences Inc | Indole compounds as androgen receptor modulators |
| WO2022057842A1 (en) * | 2020-09-18 | 2022-03-24 | Sunshine Lake Pharma Co., Ltd. | Preparation method of substituted pyrimidine piperazine compounds |
| CR20250176A (es) * | 2022-10-12 | 2025-06-25 | Maze Therapeutics Inc | Inhibidores del miembro 19 de la familia de portadores de solutos 6a (slc6a19) y métodos de uso de los mismos |
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| KR101298967B1 (ko) | 2004-03-30 | 2013-09-02 | 버텍스 파마슈티칼스 인코포레이티드 | Ｊａｋ 및 기타 단백질 키나제의 억제제로서 유용한 아자인돌 |
| RU2453548C2 (ru) | 2006-01-17 | 2012-06-20 | Вертекс Фармасьютикалз Инкорпорейтед | Азаиндолы, полезные в качестве ингибиторов янус-киназ |
| TWI483941B (zh) * | 2009-06-17 | 2015-05-11 | Vertex Pharma | 流感病毒複製之抑制劑 |
| JP5876051B2 (ja) * | 2010-09-08 | 2016-03-02 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ | インフルエンザウィルス感染の治療に使用するためのインダゾール誘導体 |
| MX2013006836A (es) * | 2010-12-16 | 2013-09-26 | Vertex Pharma | Inhibidores de la replicacion de los virus de la influenza. |
| KR20130128435A (ko) * | 2010-12-16 | 2013-11-26 | 버텍스 파마슈티칼스 인코포레이티드 | 인플루엔자 바이러스 복제의 억제제 |
| UA118010C2 (uk) * | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| RU2673064C2 (ru) | 2011-09-01 | 2018-11-22 | Ф. Хоффманн-Ля Рош Аг | Пирролопиразиновые ингибиторы киназы |
| EP2858984A1 (en) | 2012-06-08 | 2015-04-15 | Vertex Pharmaceuticals Inc. | Inhibitors of influenza viruses replication |
| SMT201900450T1 (it) | 2013-11-13 | 2019-09-09 | Vertex Pharma | Inibitori della replicazione di virus dell’influenza |
| AR101401A1 (es) | 2014-08-08 | 2016-12-14 | Bayer Cropscience Ag | Derivados de bipirazol, sustituidos con halógeno |
| UY36255A (es) | 2014-08-08 | 2016-01-29 | Bayer Cropscience Ag | Compuestos sustituidos por halógeno novedosos |
| SG11201700956VA (en) | 2014-08-08 | 2017-03-30 | Janssen Sciences Ireland Uc | Indoles for use in influenza virus infection |
| CN104592038A (zh) | 2015-01-12 | 2015-05-06 | 烟台万润精细化工股份有限公司 | 一种5,5-二甲基-1,3-环己二胺的制备方法 |
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2015
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- 2015-08-07 MA MA040547A patent/MA40547A/fr unknown
- 2015-08-07 WO PCT/EP2015/068257 patent/WO2016020526A1/en not_active Ceased
- 2015-08-07 UA UAA201702154A patent/UA124609C2/uk unknown
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- 2015-08-07 AU AU2015298876A patent/AU2015298876B2/en not_active Ceased
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- 2017-02-07 CL CL2017000309A patent/CL2017000309A1/es unknown
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Also Published As
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| CL2017000309A1 (es) | 2017-08-18 |
| UA124609C2 (uk) | 2021-10-20 |
| SG11201700956VA (en) | 2017-03-30 |
| US20170226102A1 (en) | 2017-08-10 |
| CA2954751A1 (en) | 2016-02-11 |
| KR20170039275A (ko) | 2017-04-10 |
| CN106573920A (zh) | 2017-04-19 |
| WO2016020526A1 (en) | 2016-02-11 |
| KR102488479B1 (ko) | 2023-01-12 |
| IL250408B (en) | 2020-08-31 |
| IL250408A0 (en) | 2017-03-30 |
| AU2015298876B2 (en) | 2020-02-13 |
| CN106573920B (zh) | 2020-11-10 |
| MA40547A (fr) | 2017-06-14 |
| BR112017002370A2 (pt) | 2017-12-05 |
| MX381488B (es) | 2025-03-12 |
| CA2954751C (en) | 2023-01-17 |
| ZA201700952B (en) | 2018-12-19 |
| EA201790266A1 (ru) | 2017-06-30 |
| PH12017500207A1 (en) | 2017-07-10 |
| MX2017001752A (es) | 2018-02-08 |
| PH12017500207B1 (en) | 2017-07-10 |
| AU2015298876A1 (en) | 2017-02-02 |
| EP3177609A1 (en) | 2017-06-14 |
| JP2017523225A (ja) | 2017-08-17 |
| US10597390B2 (en) | 2020-03-24 |
| BR112017002370B1 (pt) | 2022-11-22 |
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