JP2015535839A5 - - Google Patents
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- Publication number
- JP2015535839A5 JP2015535839A5 JP2015533635A JP2015533635A JP2015535839A5 JP 2015535839 A5 JP2015535839 A5 JP 2015535839A5 JP 2015533635 A JP2015533635 A JP 2015533635A JP 2015533635 A JP2015533635 A JP 2015533635A JP 2015535839 A5 JP2015535839 A5 JP 2015535839A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- carboxylic acid
- compound
- amino
- heteroarylalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC(*/C1=C\CC#CCCC1)OC(C(N)=*)=C(C)NN=C(N)N Chemical compound CC(*/C1=C\CC#CCCC1)OC(C(N)=*)=C(C)NN=C(N)N 0.000 description 4
- QKFLVZGGHLUMLZ-OEMAIJDKSA-N CCCCN[C@@](C1)(C1(C)OCc1cccnc1)N/C=N/CN Chemical compound CCCCN[C@@](C1)(C1(C)OCc1cccnc1)N/C=N/CN QKFLVZGGHLUMLZ-OEMAIJDKSA-N 0.000 description 1
- TVZORZUMEIQISH-UHFFFAOYSA-N COC1=CC=C(CCCO)CC1 Chemical compound COC1=CC=C(CCCO)CC1 TVZORZUMEIQISH-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12306196.2 | 2012-10-01 | ||
| EP12306196.2A EP2712866A1 (en) | 2012-10-01 | 2012-10-01 | 1,2,4-triazine derivatives for the treatment of viral infections |
| PCT/EP2013/070488 WO2014053516A1 (en) | 2012-10-01 | 2013-10-01 | 1,2,4-triazine derivatives for the treatment of viral infections. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015535839A JP2015535839A (ja) | 2015-12-17 |
| JP2015535839A5 true JP2015535839A5 (enExample) | 2016-11-10 |
| JP6298998B2 JP6298998B2 (ja) | 2018-03-28 |
Family
ID=46982496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015533635A Expired - Fee Related JP6298998B2 (ja) | 2012-10-01 | 2013-10-01 | ウイルス感染を治療するための１，２，４−トリアジン誘導体 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9416114B2 (enExample) |
| EP (2) | EP2712866A1 (enExample) |
| JP (1) | JP6298998B2 (enExample) |
| KR (1) | KR102138393B1 (enExample) |
| CN (1) | CN104812747B (enExample) |
| AU (1) | AU2013326579B2 (enExample) |
| BR (1) | BR112015007310B1 (enExample) |
| CA (1) | CA2886630C (enExample) |
| CL (1) | CL2015000787A1 (enExample) |
| EA (1) | EA026236B1 (enExample) |
| ES (1) | ES2616496T3 (enExample) |
| IL (1) | IL237871A (enExample) |
| IN (1) | IN2015DN03327A (enExample) |
| MX (1) | MX348229B (enExample) |
| MY (1) | MY182558A (enExample) |
| NZ (1) | NZ706354A (enExample) |
| PH (1) | PH12015500724A1 (enExample) |
| SG (1) | SG11201502522WA (enExample) |
| UA (1) | UA114644C2 (enExample) |
| WO (1) | WO2014053516A1 (enExample) |
| ZA (1) | ZA201502240B (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101946499B1 (ko) | 2011-04-08 | 2019-02-11 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 바이러스 감염 치료를 위한 피리미딘 유도체 |
| EP2776439B1 (en) | 2011-11-09 | 2018-07-04 | Janssen Sciences Ireland UC | Purine derivatives for the treatment of viral infections |
| CA2874800C (en) | 2012-07-13 | 2021-04-06 | Janssen R&D Ireland | Macrocyclic purines for the treatment of viral infections |
| NZ705589A (en) | 2012-10-10 | 2019-05-31 | Janssen Sciences Ireland Uc | Pyrrolo[3,2-d]pyrimidine derivatives for the treatment of viral infections and other diseases |
| AU2013346793B2 (en) | 2012-11-16 | 2018-03-08 | Janssen Sciences Ireland Uc | Heterocyclic substituted 2-amino-quinazoline derivatives for the treatment of viral infections |
| KR102225233B1 (ko) | 2013-02-21 | 2021-03-09 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 바이러스 감염의 치료를 위한 2-아미노피리미딘 유도체 |
| MX366481B (es) | 2013-03-29 | 2019-07-09 | Janssen Sciences Ireland Uc | Deaza-purinonas macrociclicas para el tratamiento de infecciones virales. |
| MY188071A (en) | 2013-05-24 | 2021-11-16 | Janssen Sciences Ireland Uc | Pyridone derivatives for the treatment of viral infections and further diseases |
| CN109369643B (zh) | 2013-06-27 | 2021-05-18 | 爱尔兰詹森科学公司 | 用于治疗病毒感染和其他疾病的吡咯并[3,2-d]嘧啶衍生物 |
| EP3027624B1 (en) | 2013-07-30 | 2018-09-12 | Janssen Sciences Ireland UC | Thieno[3,2-d]pyrimidines derivatives for the treatment of viral infections |
| WO2018002319A1 (en) | 2016-07-01 | 2018-01-04 | Janssen Sciences Ireland Uc | Dihydropyranopyrimidines for the treatment of viral infections |
| WO2018060317A1 (en) * | 2016-09-29 | 2018-04-05 | Janssen Sciences Ireland Uc | Pyrimidine prodrugs for the treatment of viral infections and further diseases |
| TW202415645A (zh) | 2018-03-01 | 2024-04-16 | 愛爾蘭商健生科學愛爾蘭無限公司 | ２，４－二胺基喹唑啉衍生物及其醫學用途 |
| WO2020162705A1 (ko) | 2019-02-08 | 2020-08-13 | 성균관대학교산학협력단 | 톨-유사 수용체 7 또는 8 작용자와 콜레스테롤의 결합체 및 그 용도 |
| CA3170551A1 (en) | 2020-03-02 | 2021-09-10 | Yong Taik Lim | Live-pathogen-mimetic nanoparticles based on pathogen cell wall skeleton, and production method thereof |
| WO2022031011A1 (ko) | 2020-08-04 | 2022-02-10 | 성균관대학교산학협력단 | 동력학적으로 작용하는 아주번트 앙상블 |
| JP2023536954A (ja) | 2020-08-04 | 2023-08-30 | プロジェニア インコーポレイテッド | 活性化部位が一時的に不活性化したトール様受容体７または８作用薬と機能性薬物の結合体およびその用途 |
| US20230346924A1 (en) | 2020-08-04 | 2023-11-02 | Progeneer Inc. | Mrna vaccine comprising adjuvant capable of kinetic control |
| WO2024151953A1 (en) * | 2023-01-15 | 2024-07-18 | Viradem Inc. | Compounds and methods for treating diseases caused by sars-cov-2 and other coronaviruses |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2485531A1 (fr) * | 1980-06-25 | 1981-12-31 | Fabre Sa Pierre | Nouveaux n-oxydes de diaryl-5,6 as triazines 1-2-4, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
| KR19990044383A (ko) | 1996-07-03 | 1999-06-25 | 나가시마 카쭈시게, 노미야마 아키히코 | 신규 퓨린 유도체 |
| US6329381B1 (en) | 1997-11-28 | 2001-12-11 | Sumitomo Pharmaceuticals Company, Limited | Heterocyclic compounds |
| JP5031564B2 (ja) * | 2004-08-10 | 2012-09-19 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Ｈｉｖ抑制１，２，４−トリアジン−６−オン誘導体 |
| EP1888587A1 (en) | 2005-05-04 | 2008-02-20 | Pfizer Limited | 2-amido-6-amino-8-oxopurine derivatives as toll-like receptor modulators for the treatment of cancer and viral infections, such as hepatitis c |
| CN101296907B (zh) * | 2005-09-01 | 2013-03-27 | 弗·哈夫曼-拉罗切有限公司 | 作为p2x3和p2x2/3调节剂的二氨基嘧啶类 |
| RU2352565C1 (ru) * | 2007-10-08 | 2009-04-20 | Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет" | 3-амино-6-ароилметил-5-гидрокси-1,2,4-триазины и способ их получения |
| PE20091236A1 (es) * | 2007-11-22 | 2009-09-16 | Astrazeneca Ab | Derivados de pirimidina como immunomoduladores de tlr7 |
| WO2012067269A1 (en) * | 2010-11-19 | 2012-05-24 | Dainippon Sumitomo Pharma Co., Ltd. | Aminoalkoxyphenyl compounds and their use in the treatment of disease |
-
2012
- 2012-10-01 EP EP12306196.2A patent/EP2712866A1/en not_active Withdrawn
-
2013
- 2013-10-01 MX MX2015004160A patent/MX348229B/es active IP Right Grant
- 2013-10-01 EA EA201500383A patent/EA026236B1/ru not_active IP Right Cessation
- 2013-10-01 BR BR112015007310-7A patent/BR112015007310B1/pt not_active IP Right Cessation
- 2013-10-01 SG SG11201502522WA patent/SG11201502522WA/en unknown
- 2013-10-01 MY MYPI2015000804A patent/MY182558A/en unknown
- 2013-10-01 AU AU2013326579A patent/AU2013326579B2/en not_active Ceased
- 2013-10-01 ES ES13773690.6T patent/ES2616496T3/es active Active
- 2013-10-01 KR KR1020157009515A patent/KR102138393B1/ko not_active Expired - Fee Related
- 2013-10-01 US US14/432,269 patent/US9416114B2/en active Active
- 2013-10-01 NZ NZ706354A patent/NZ706354A/en not_active IP Right Cessation
- 2013-10-01 CA CA2886630A patent/CA2886630C/en active Active
- 2013-10-01 IN IN3327DEN2015 patent/IN2015DN03327A/en unknown
- 2013-10-01 EP EP13773690.6A patent/EP2903976B1/en active Active
- 2013-10-01 UA UAA201504222A patent/UA114644C2/uk unknown
- 2013-10-01 JP JP2015533635A patent/JP6298998B2/ja not_active Expired - Fee Related
- 2013-10-01 CN CN201380050972.5A patent/CN104812747B/zh not_active Expired - Fee Related
- 2013-10-01 WO PCT/EP2013/070488 patent/WO2014053516A1/en not_active Ceased
-
2015
- 2015-03-22 IL IL237871A patent/IL237871A/en active IP Right Grant
- 2015-03-30 CL CL2015000787A patent/CL2015000787A1/es unknown
- 2015-03-31 ZA ZA2015/02240A patent/ZA201502240B/en unknown
- 2015-03-31 PH PH12015500724A patent/PH12015500724A1/en unknown
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