UA116083C2 - Похідні пурину для лікування вірусних інфекцій - Google Patents

Похідні пурину для лікування вірусних інфекцій

Info

Publication number
UA116083C2
UA116083C2 UAA201403138A UAA201403138A UA116083C2 UA 116083 C2 UA116083 C2 UA 116083C2 UA A201403138 A UAA201403138 A UA A201403138A UA A201403138 A UAA201403138 A UA A201403138A UA 116083 C2 UA116083 C2 UA 116083C2
Authority
UA
Ukraine
Prior art keywords
treatment
purine derivatives
viral infections
purine
derivatives
Prior art date
Application number
UAA201403138A
Other languages
English (en)
Inventor
Жан-Франсуа Бонфанті
Фредерік Марк Моріс Дубле
Вернер Ембрехтс
Жером Мішель Клод Фортін
Гован Девід Крейг Мак
Філіп Мюллер
П'єр Жан-Марі Бернар Рабуассон
Original Assignee
ЯНССЕН САЙЄНСІЗ АЙРЛЕНД ЮСі
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47178000&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA116083(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ЯНССЕН САЙЄНСІЗ АЙРЛЕНД ЮСі filed Critical ЯНССЕН САЙЄНСІЗ АЙРЛЕНД ЮСі
Publication of UA116083C2 publication Critical patent/UA116083C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Похідні пурину для лікування вірусних інфекцій (I). Даний винахід стосується похідних пурину формули (І), способів їх отримання, фармацевтичних композицій і їх застосування у лікуванні вірусних інфекцій.
UAA201403138A 2011-11-09 2012-11-08 Похідні пурину для лікування вірусних інфекцій UA116083C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11188511 2011-11-09
PCT/EP2012/072090 WO2013068438A1 (en) 2011-11-09 2012-11-08 Purine derivatives for the treatment of viral infections

Publications (1)

Publication Number Publication Date
UA116083C2 true UA116083C2 (uk) 2018-02-12

Family

ID=47178000

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201403138A UA116083C2 (uk) 2011-11-09 2012-11-08 Похідні пурину для лікування вірусних інфекцій

Country Status (27)

Country Link
US (4) US9556176B2 (uk)
EP (1) EP2776439B1 (uk)
JP (1) JP6349256B2 (uk)
KR (1) KR102025276B1 (uk)
CN (2) CN104066733A (uk)
AU (1) AU2012334127B2 (uk)
BR (2) BR122019020718B1 (uk)
CA (1) CA2850448C (uk)
CL (1) CL2014001205A1 (uk)
CY (1) CY1121452T1 (uk)
DK (1) DK2776439T3 (uk)
EA (2) EA033830B1 (uk)
ES (1) ES2690082T3 (uk)
HR (1) HRP20181497T1 (uk)
HU (1) HUE040541T2 (uk)
IL (1) IL232046A (uk)
IN (1) IN2014MN00862A (uk)
LT (1) LT2776439T (uk)
MX (1) MX347596B (uk)
MY (1) MY173422A (uk)
PL (1) PL2776439T3 (uk)
PT (1) PT2776439T (uk)
RS (1) RS57851B1 (uk)
SG (1) SG11201401244TA (uk)
SI (1) SI2776439T1 (uk)
UA (1) UA116083C2 (uk)
WO (1) WO2013068438A1 (uk)

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