IN2015DN03327A - - Google Patents
Info
- Publication number
- IN2015DN03327A IN2015DN03327A IN3327DEN2015A IN2015DN03327A IN 2015DN03327 A IN2015DN03327 A IN 2015DN03327A IN 3327DEN2015 A IN3327DEN2015 A IN 3327DEN2015A IN 2015DN03327 A IN2015DN03327 A IN 2015DN03327A
- Authority
- IN
- India
- Prior art keywords
- processes
- preparation
- pharmaceutical compositions
- relates
- viral infections
- Prior art date
Links
- 150000003920 1,2,4-triazines Chemical class 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epidemiology (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
This invention relates to 1, 2, 4- triazine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12306196.2A EP2712866A1 (en) | 2012-10-01 | 2012-10-01 | 1,2,4-triazine derivatives for the treatment of viral infections |
| PCT/EP2013/070488 WO2014053516A1 (en) | 2012-10-01 | 2013-10-01 | 1,2,4-triazine derivatives for the treatment of viral infections. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2015DN03327A true IN2015DN03327A (en) | 2015-10-09 |
Family
ID=46982496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3327DEN2015 IN2015DN03327A (en) | 2012-10-01 | 2013-10-01 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9416114B2 (en) |
| EP (2) | EP2712866A1 (en) |
| JP (1) | JP6298998B2 (en) |
| KR (1) | KR102138393B1 (en) |
| CN (1) | CN104812747B (en) |
| AU (1) | AU2013326579B2 (en) |
| BR (1) | BR112015007310B1 (en) |
| CA (1) | CA2886630C (en) |
| CL (1) | CL2015000787A1 (en) |
| EA (1) | EA026236B1 (en) |
| ES (1) | ES2616496T3 (en) |
| IL (1) | IL237871A (en) |
| IN (1) | IN2015DN03327A (en) |
| MX (1) | MX348229B (en) |
| MY (1) | MY182558A (en) |
| NZ (1) | NZ706354A (en) |
| PH (1) | PH12015500724B1 (en) |
| SG (1) | SG11201502522WA (en) |
| UA (1) | UA114644C2 (en) |
| WO (1) | WO2014053516A1 (en) |
| ZA (1) | ZA201502240B (en) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SMT201800527T1 (en) | 2011-04-08 | 2018-11-09 | Janssen Sciences Ireland Uc | Pyrimidine derivatives for the treatment of viral infections |
| UA116083C2 (en) | 2011-11-09 | 2018-02-12 | ЯНССЕН САЙЄНСІЗ АЙРЛЕНД ЮСі | PURINE DERIVATIVES FOR TREATMENT OF VIRAL INFECTIONS |
| PT2872515T (en) | 2012-07-13 | 2016-07-27 | Janssen Sciences Ireland Uc | Macrocyclic purines for the treatment of viral infections |
| SG11201502622VA (en) | 2012-10-10 | 2015-05-28 | Janssen Sciences Ireland Uc | PYRROLO[3,2-<i>D</i>]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER DISEASES |
| NZ706226A (en) | 2012-11-16 | 2019-09-27 | Janssen Sciences Ireland Uc | Heterocyclic substituted 2-amino-quinazoline derivatives for the treatment of viral infections |
| WO2014128189A1 (en) | 2013-02-21 | 2014-08-28 | Janssen R&D Ireland | 2-aminopyrimidine derivatives for the treatment of viral infections |
| JP6336036B2 (en) | 2013-03-29 | 2018-06-06 | ヤンセン・サイエンシズ・アイルランド・ユーシー | Macrocyclic deazaprinone for the treatment of viral infections |
| WO2014187932A1 (en) | 2013-05-24 | 2014-11-27 | Janssen R&D Ireland | Pyridone derivatives for the treatment of viral infections and further diseases |
| DK3030563T3 (en) | 2013-06-27 | 2017-11-20 | Janssen Sciences Ireland Uc | PYRROLO- [3,2-D] PYRIMIDINE DERIVATIVES FOR TREATING VIRAL INFECTIONS AND OTHER DISEASES |
| JP6401788B2 (en) | 2013-07-30 | 2018-10-10 | ヤンセン・サイエンシズ・アイルランド・ユーシー | Thieno [3,2-d] pyrimidine derivatives for viral infection treatment |
| CN109476675B (en) | 2016-07-01 | 2022-12-09 | 爱尔兰詹森科学公司 | Dihydropyranopyrimidine derivatives for the treatment of viral infections |
| AU2017335205B2 (en) | 2016-09-29 | 2021-11-04 | Janssen Sciences Ireland Unlimited Company | Pyrimidine prodrugs for the treatment of viral infections and further diseases |
| TW201945003A (en) | 2018-03-01 | 2019-12-01 | 愛爾蘭商健生科學愛爾蘭無限公司 | 2,4-diaminoquinazoline derivatives and medical uses thereof |
| BR112021015577A8 (en) | 2019-02-08 | 2021-10-05 | Research & Business Found Sungkyunkwan Univ | Toll-like receptor 7/8 agonist cholesterol-complex, nanoparticle composition, adjuvant composition, vaccine composition, composition for regulating immune function, pharmaceutical composition and use of the complex |
| WO2021177679A1 (en) | 2020-03-02 | 2021-09-10 | 성균관대학교산학협력단 | Live-pathogen-mimetic nanoparticles based on pathogen cell wall skeleton, and production method thereof |
| JP7690222B2 (en) | 2020-08-04 | 2025-06-10 | プロジェニア インコーポレイテッド | mRNA vaccines containing kinetically controllable adjuvants |
| WO2022031057A1 (en) | 2020-08-04 | 2022-02-10 | 성균관대학교산학협력단 | Conjugate of functional drug and toll-like receptor 7 or 8 agonist of which active site is temporarily inactivated and use thereof |
| EP4194008A4 (en) | 2020-08-04 | 2025-01-08 | Progeneer Inc. | KINETIC ACTION ADJUVANT SET |
| WO2024151953A1 (en) * | 2023-01-15 | 2024-07-18 | Viradem Inc. | Compounds and methods for treating diseases caused by sars-cov-2 and other coronaviruses |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2485531A1 (en) * | 1980-06-25 | 1981-12-31 | Fabre Sa Pierre | NOVEL DIARYL-5,6 AS TRIAZINES 1-2-4 N-OXIDES, THEIR USE AS DRUGS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| CA2230808C (en) | 1996-07-03 | 2006-08-15 | Japan Energy Corporation | A novel purine derivative |
| WO1999028321A1 (en) | 1997-11-28 | 1999-06-10 | Sumitomo Pharmaceuticals Company, Limited | Novel heterocyclic compounds |
| AU2005271161B2 (en) * | 2004-08-10 | 2011-05-12 | Janssen Pharmaceutica N.V. | HIV inhibiting 1,2,4-triazin-6-one derivatives |
| AU2006242920A1 (en) | 2005-05-04 | 2006-11-09 | Pfizer Limited | 2-amido-6-amino-8-oxopurine derivatives as Toll-Like receptor modulators for the treatment of cancer and viral infections, such as hepatitis C |
| ES2612890T3 (en) * | 2005-09-01 | 2017-05-19 | F. Hoffmann-La Roche Ag | Diaminopyrimidines as modulators of P2X3 and P2X2 / 3 |
| RU2352565C1 (en) * | 2007-10-08 | 2009-04-20 | Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет" | 3-amino-6-aroylmethyl-5-hydroxy-1,2,4-triazines and methods of obtaining them |
| PE20091236A1 (en) * | 2007-11-22 | 2009-09-16 | Astrazeneca Ab | PYRIMIDINE DERIVATIVES AS IMMUNOMODULATORS OF TLR7 |
| WO2012067269A1 (en) * | 2010-11-19 | 2012-05-24 | Dainippon Sumitomo Pharma Co., Ltd. | Aminoalkoxyphenyl compounds and their use in the treatment of disease |
-
2012
- 2012-10-01 EP EP12306196.2A patent/EP2712866A1/en not_active Withdrawn
-
2013
- 2013-10-01 EP EP13773690.6A patent/EP2903976B1/en active Active
- 2013-10-01 MY MYPI2015000804A patent/MY182558A/en unknown
- 2013-10-01 MX MX2015004160A patent/MX348229B/en active IP Right Grant
- 2013-10-01 AU AU2013326579A patent/AU2013326579B2/en not_active Ceased
- 2013-10-01 SG SG11201502522WA patent/SG11201502522WA/en unknown
- 2013-10-01 NZ NZ706354A patent/NZ706354A/en not_active IP Right Cessation
- 2013-10-01 ES ES13773690.6T patent/ES2616496T3/en active Active
- 2013-10-01 KR KR1020157009515A patent/KR102138393B1/en not_active Expired - Fee Related
- 2013-10-01 JP JP2015533635A patent/JP6298998B2/en active Active
- 2013-10-01 IN IN3327DEN2015 patent/IN2015DN03327A/en unknown
- 2013-10-01 WO PCT/EP2013/070488 patent/WO2014053516A1/en active Application Filing
- 2013-10-01 CA CA2886630A patent/CA2886630C/en active Active
- 2013-10-01 UA UAA201504222A patent/UA114644C2/en unknown
- 2013-10-01 EA EA201500383A patent/EA026236B1/en not_active IP Right Cessation
- 2013-10-01 US US14/432,269 patent/US9416114B2/en active Active
- 2013-10-01 CN CN201380050972.5A patent/CN104812747B/en not_active Expired - Fee Related
- 2013-10-01 BR BR112015007310-7A patent/BR112015007310B1/en not_active IP Right Cessation
-
2015
- 2015-03-22 IL IL237871A patent/IL237871A/en active IP Right Grant
- 2015-03-30 CL CL2015000787A patent/CL2015000787A1/en unknown
- 2015-03-31 ZA ZA2015/02240A patent/ZA201502240B/en unknown
- 2015-03-31 PH PH12015500724A patent/PH12015500724B1/en unknown
Also Published As
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