|
CA2297294C
(en)
|
1989-05-15 |
2005-11-08 |
Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic |
Phosphonomethoxymethylpurine/pyrimidine derivatives
|
|
IT1249732B
(it)
|
1991-11-26 |
1995-03-09 |
Angeletti P Ist Richerche Bio |
Oligonucleotidi antisenso.
|
|
US5977061A
(en)
|
1995-04-21 |
1999-11-02 |
Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic |
N6 - substituted nucleotide analagues and their use
|
|
HUP0001186A3
(en)
|
1996-10-16 |
2002-04-29 |
Icn Pharmaceuticals Inc Costa |
Purine l-nucleosides,analogs and pharmaceutical compositions thereof
|
|
ZA986614B
(en)
*
|
1997-07-25 |
1999-01-27 |
Gilead Sciences |
Nucleotide analog composition
|
|
AU2787199A
(en)
|
1998-02-25 |
1999-09-15 |
Emory University |
2'-fluoronucleosides
|
|
IN191496B
(enExample)
|
1999-07-30 |
2003-12-06 |
Ranbaxy Lab Ltd |
|
|
ES2319732T3
(es)
|
2000-04-13 |
2009-05-12 |
Pharmasset, Inc. |
Derivados de nucleosido 3'- o 2'-hidroximetilo sustituido para el tratamiento de infecciones virales.
|
|
MY164523A
(en)
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
|
JP5230052B2
(ja)
|
2000-05-26 |
2013-07-10 |
イデニクス（ケイマン）リミテツド |
フラビウイルスおよびペスチウイルス治療のための方法および組成物
|
|
ATE491459T1
(de)
|
2000-10-18 |
2011-01-15 |
Pharmasset Inc |
Modifizierte nukleoside zur behandlung von virusinfektionen und abnormaler zellulärer proliferation
|
|
US20030124512A1
(en)
|
2000-10-18 |
2003-07-03 |
Lieven Stuyver |
Simultaneous quantification of nucleic acids in diseased cells
|
|
US7105499B2
(en)
|
2001-01-22 |
2006-09-12 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
DZ3487A1
(fr)
|
2001-01-22 |
2002-07-25 |
Merck Sharp & Dohme |
Derives de nucleoside comme inhibiteurs de l'arn polymerase virale d'arn-dependant
|
|
US8481712B2
(en)
|
2001-01-22 |
2013-07-09 |
Merck Sharp & Dohme Corp. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
GB0112617D0
(en)
|
2001-05-23 |
2001-07-18 |
Hoffmann La Roche |
Antiviral nucleoside derivatives
|
|
GB0114286D0
(en)
|
2001-06-12 |
2001-08-01 |
Hoffmann La Roche |
Nucleoside Derivatives
|
|
US6949522B2
(en)
|
2001-06-22 |
2005-09-27 |
Pharmasset, Inc. |
β-2′- or 3′-halonucleosides
|
|
WO2003026589A2
(en)
|
2001-09-28 |
2003-04-03 |
Idenix (Cayman) Limited |
Methods and compositions for treating hepatitis c virus using 4'-modified nucleosides
|
|
GB2383042A
(en)
|
2001-10-18 |
2003-06-18 |
Cipla Ltd |
Amorphous alendronate sodium
|
|
AU2002351077A1
(en)
|
2001-11-05 |
2003-05-19 |
Exiqon A/S |
Oligonucleotides modified with novel alpha-l-rna analogues
|
|
US7388002B2
(en)
|
2001-11-14 |
2008-06-17 |
Biocryst Pharmaceuticals, Inc. |
Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases
|
|
KR100978904B1
(ko)
|
2001-12-14 |
2010-08-31 |
파마셋 인코포레이티드 |
바이러스 감염 치료용 ｎ4-아실사이토신 뉴클레오사이드
|
|
WO2003053360A2
(en)
|
2001-12-20 |
2003-07-03 |
Pharmassett Ltd. |
Treatment of ebv and khsv infection and associated abnormal cellular proliferation
|
|
WO2003062256A1
(en)
|
2002-01-17 |
2003-07-31 |
Ribapharm Inc. |
2'-beta-modified-6-substituted adenosine analogs and their use as antiviral agents
|
|
EP1485395A4
(en)
|
2002-02-28 |
2011-04-13 |
Biota Scient Management |
NUCLEOTIDE MIMETICS AND PRODRUGS THEREOF
|
|
US20040063658A1
(en)
|
2002-05-06 |
2004-04-01 |
Roberts Christopher Don |
Nucleoside derivatives for treating hepatitis C virus infection
|
|
AP2005003213A0
(en)
|
2002-06-28 |
2005-03-31 |
Univ Cagliari |
2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections.
|
|
US7608600B2
(en)
|
2002-06-28 |
2009-10-27 |
Idenix Pharmaceuticals, Inc. |
Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
|
|
NZ537662A
(en)
|
2002-06-28 |
2007-10-26 |
Idenix Cayman Ltd |
2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
|
|
WO2004003000A2
(en)
|
2002-06-28 |
2004-01-08 |
Idenix (Cayman) Limited |
1’-, 2'- and 3'- modified nucleoside derivatives for treating flaviviridae infections
|
|
TW200500375A
(en)
|
2002-06-28 |
2005-01-01 |
Idenix Cayman Ltd |
Modified 2' and 3'-nucleoside prodrugs for treating flaviviridae
|
|
AU2003256619A1
(en)
|
2002-07-24 |
2004-02-09 |
Isis Pharmaceuticals, Inc. |
Pyrrolopyrimidine thionucleoside analogs as antivirals
|
|
SG174624A1
(en)
|
2002-08-01 |
2011-10-28 |
Pharmasset Inc |
Compounds with the bicyclo[4.2.1]nonane system for the treatment of flaviviridae infections
|
|
US20040067877A1
(en)
|
2002-08-01 |
2004-04-08 |
Schinazi Raymond F. |
2', 3'-Dideoxynucleoside analogues for the treatment or prevention of Flaviviridae infections
|
|
WO2004014312A2
(en)
|
2002-08-08 |
2004-02-19 |
Sirna Therapeutics, Inc. |
Small-mer compositions and methods of use
|
|
US7824851B2
(en)
|
2002-11-15 |
2010-11-02 |
Idenix Pharmaceuticals, Inc. |
2′-branched nucleosides and Flaviviridae mutation
|
|
TWI294882B
(en)
|
2002-12-09 |
2008-03-21 |
Hoffmann La Roche |
Anhydrous crystalline azido cytosine hemisulfate derivative
|
|
PT2404890T
(pt)
|
2003-01-23 |
2017-10-23 |
Esperion Therapeutics Inc |
Compostos de hidroxilo e composições para gestão do colesterol e utilizações relacionadas
|
|
AR043006A1
(es)
|
2003-02-12 |
2005-07-13 |
Merck & Co Inc |
Proceso para preparar ribonucleosidos ramificados
|
|
WO2004074350A2
(en)
*
|
2003-02-21 |
2004-09-02 |
Hetero Drugs Limited |
Bicalutamide polymorphs
|
|
WO2004091499A2
(en)
|
2003-04-09 |
2004-10-28 |
Neose Technologies, Inc. |
Intracellular formation of peptide conjugates
|
|
CA2523083C
(en)
|
2003-04-25 |
2014-07-08 |
Gilead Sciences, Inc. |
Antiviral phosphonate analogs
|
|
US20040259934A1
(en)
|
2003-05-01 |
2004-12-23 |
Olsen David B. |
Inhibiting Coronaviridae viral replication and treating Coronaviridae viral infection with nucleoside compounds
|
|
US20040229839A1
(en)
|
2003-05-14 |
2004-11-18 |
Biocryst Pharmaceuticals, Inc. |
Substituted nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases
|
|
WO2005020884A2
(en)
|
2003-05-14 |
2005-03-10 |
Idenix (Cayman) Limited |
Nucleosides for treatment of infection by corona viruses, toga viruses and picorna viruses
|
|
WO2004106356A1
(en)
|
2003-05-27 |
2004-12-09 |
Syddansk Universitet |
Functionalized nucleotide derivatives
|
|
CN100503628C
(zh)
|
2003-05-30 |
2009-06-24 |
法莫赛特股份有限公司 |
修饰的氟化核苷类似物
|
|
MXPA05013452A
(es)
|
2003-06-19 |
2006-03-09 |
Hoffmann La Roche |
Proceso para preparar derivados de 4'-azidonucleosido.
|
|
CN1852915A
(zh)
|
2003-07-25 |
2006-10-25 |
艾登尼科斯（开曼）有限公司 |
治疗包括丙型肝炎的黄病毒科病毒所致疾病的嘌呤核苷类似物
|
|
DE10335061B4
(de)
|
2003-07-31 |
2005-11-17 |
Wacker-Chemie Gmbh |
Verfahren zur Herstellung von OH-geschützten [4-(2,6-damino-9H-purin-9-yl)-1,3-dioxolan-2-yl]methanol-Derivaten
|
|
WO2005021568A2
(en)
|
2003-08-27 |
2005-03-10 |
Biota, Inc. |
Novel tricyclic nucleosides or nucleotides as therapeutic agents
|
|
WO2005090370A1
(en)
|
2004-02-05 |
2005-09-29 |
The Regents Of The University Of California |
Pharmacologically active agents containing esterified phosphonates and methods for use thereof
|
|
US20050182252A1
(en)
|
2004-02-13 |
2005-08-18 |
Reddy K. R. |
Novel 2'-C-methyl nucleoside derivatives
|
|
US7534767B2
(en)
|
2004-06-15 |
2009-05-19 |
Merck & Co., Inc. |
C-purine nucleoside analogs as inhibitors of RNA-dependent RNA viral polymerase
|
|
WO2006002231A1
(en)
|
2004-06-22 |
2006-01-05 |
Biocryst Pharmaceuticals, Inc. |
Aza nucleosides, preparation thereof and use as inhibitors of rna viral polymerases
|
|
JP5080973B2
(ja)
|
2004-06-24 |
2012-11-21 |
メルク・シャープ・エンド・ドーム・コーポレイション |
Ｒｎａ依存性ｒｎａウイルスの感染を処置するためのヌクレオシドアリールホスホルアミダート
|
|
RU2007103308A
(ru)
|
2004-06-29 |
2008-08-10 |
Эвери Деннисон Копэрейшн (Us) |
Застежка для подгузника (варианты), экструзивный слоистый материал и способ его получения
|
|
CN101023094B
(zh)
|
2004-07-21 |
2011-05-18 |
法莫赛特股份有限公司 |
烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
|
|
BRPI0515279A
(pt)
|
2004-09-14 |
2008-07-15 |
Pharmasset Inc |
preparação de ribofuranosil pirimidinas e purinas 2'fluoro-2'-alquil- substituìdas ou outras opcionalmente substituìdas e seus derivados
|
|
KR20070100237A
(ko)
|
2004-10-29 |
2007-10-10 |
바이오크리스트 파마수티컬즈, 인코퍼레이티드 |
치료용 푸로피리미딘 및 티에노피리미딘
|
|
WO2006063149A1
(en)
|
2004-12-09 |
2006-06-15 |
Regents Of The University Of Minnesota |
Nucleosides with antiviral and anticancer activity
|
|
MX2007006961A
(es)
|
2004-12-10 |
2007-10-04 |
Univ Emory |
Analogos nucleosidos de ciclobutilo 2' y 3'-sustituidos para el tratamiento de infeccciones virales y proliferacion celular anormal.
|
|
WO2006063717A2
(en)
|
2004-12-16 |
2006-06-22 |
Febit Biotech Gmbh |
Polymerase-independent analysis of the sequence of polynucleotides
|
|
US8802840B2
(en)
|
2005-03-08 |
2014-08-12 |
Biota Scientific Management Pty Ltd. |
Bicyclic nucleosides and nucleotides as therapeutic agents
|
|
WO2006102533A2
(en)
|
2005-03-23 |
2006-09-28 |
Neopharm, Inc. |
Pharmaceutically active lipid-based formulation of nucleoside-lipid conjugates
|
|
CA2602533A1
(en)
|
2005-03-29 |
2006-10-05 |
Biocryst Pharmaceuticals, Inc. |
Use of c-nucleoside analogs for treatment of hepatitis c related viral infections
|
|
WO2006130217A2
(en)
|
2005-04-01 |
2006-12-07 |
The Regents Of The University Of California |
Substituted phosphate esters of nucleoside phosphonates
|
|
WO2006121820A1
(en)
|
2005-05-05 |
2006-11-16 |
Valeant Research & Development |
Phosphoramidate prodrugs for treatment of viral infection
|
|
US7632821B2
(en)
|
2005-08-09 |
2009-12-15 |
Merck & Co., Inc. |
Ribonucleoside cyclic acetal derivatives for the treatment of RNA-dependent RNA viral infection
|
|
JP2009504677A
(ja)
|
2005-08-12 |
2009-02-05 |
メルク・エンド・カムパニー・インコーポレーテツド |
新規２’−ｃ−メチル及び４’−ｃ−メチルヌクレオシド誘導体
|
|
CN101287472B
(zh)
|
2005-08-15 |
2011-10-12 |
弗·哈夫曼-拉罗切有限公司 |
抗病毒的4'-取代前核苷酸的氨基磷酸酯类化合物
|
|
JP2009526850A
(ja)
|
2006-02-14 |
2009-07-23 |
メルク エンド カムパニー インコーポレーテッド |
Ｒｎａ依存性ｒｎａウイルス感染を治療するためのヌクレオシドアリールホスホルアミデート
|
|
US8895531B2
(en)
|
2006-03-23 |
2014-11-25 |
Rfs Pharma Llc |
2′-fluoronucleoside phosphonates as antiviral agents
|
|
WO2007130783A2
(en)
|
2006-05-03 |
2007-11-15 |
Chimerix, Inc. |
Metabolically stable alkoxyalkyl esters of antiviral or antiproliferative phosphonates, nucleoside phosphonates and nucleoside phosphates
|
|
US7842672B2
(en)
|
2006-07-07 |
2010-11-30 |
Gilead Sciences, Inc. |
Phosphonate inhibitors of HCV
|
|
GB0614947D0
(en)
|
2006-07-27 |
2006-09-06 |
Isis Innovation |
Epitope reduction therapy
|
|
BRPI0719174A2
(pt)
|
2006-10-10 |
2017-06-13 |
Hoffmann La Roche |
preparação de pirimidinas ribofuranosil nucleosídeos
|
|
PL216525B1
(pl)
|
2006-10-17 |
2014-04-30 |
Ct Badań Molekularnych I Makromolekularnych Polskiej Akademii Nauk |
5'-O-[(N-acylo)amidoditiofosforano] nukleozydy oraz sposób wytwarzania 5'-O-[(N-acylo)amidofosforano]-,5'-O-[(N-acylo)amidotiofosforano]-, 5'-O-[(N-acylo)amidoditiofosforano]nukleozydów
|
|
GB0623493D0
(en)
|
2006-11-24 |
2007-01-03 |
Univ Cardiff |
Chemical compounds
|
|
AU2007338899A1
(en)
|
2006-12-20 |
2008-07-03 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Nucleoside cyclic phosphoramidates for the treatment of RNA-dependent RNA viral infection
|
|
US7951789B2
(en)
|
2006-12-28 |
2011-05-31 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
EP2124555B1
(en)
|
2007-01-05 |
2015-07-08 |
Merck Sharp & Dohme Corp. |
Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection
|
|
SG177974A1
(en)
|
2007-01-12 |
2012-02-28 |
Biocryst Pharm Inc |
Antiviral nucleoside analogs
|
|
JP2010518015A
(ja)
|
2007-01-31 |
2010-05-27 |
アリオス バイオファーマ インク． |
２−５ａアナログ類およびそれらの使用方法
|
|
WO2008100447A2
(en)
|
2007-02-09 |
2008-08-21 |
Gilead Sciences, Inc. |
Nucleoside analogs for antiviral treatment
|
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
|
WO2008141079A1
(en)
|
2007-05-10 |
2008-11-20 |
Biocryst Pharmaceuticals, Inc. |
Tetrahydrofuro [3 4-d] dioxolane compounds for use in the treatment of viral infections and cancer
|
|
US20100279969A1
(en)
|
2007-05-14 |
2010-11-04 |
Rfs Pharma, Llc |
Azido purine nucleosides for treatment of viral infections
|
|
SI2014771T1
(sl)
|
2007-06-25 |
2015-04-30 |
Anadys Pharmaceuticals, Inc. |
Kontinuiran postopek encimske hidrolize
|
|
GB0712494D0
(en)
|
2007-06-27 |
2007-08-08 |
Isis Innovation |
Substrate reduction therapy
|
|
US7932240B2
(en)
|
2007-08-31 |
2011-04-26 |
Idenix Pharmaceuticals, Inc. |
Phosphadiazine HCV polymerase inhibitors IV
|
|
US20090318380A1
(en)
|
2007-11-20 |
2009-12-24 |
Pharmasset, Inc. |
2',4'-substituted nucleosides as antiviral agents
|
|
WO2009086201A1
(en)
|
2007-12-21 |
2009-07-09 |
Alios Biopharma, Inc. |
2-5a analogs and their use as anti-cancer, anti-viral and anti- paras iti c agents
|
|
US20090176732A1
(en)
|
2007-12-21 |
2009-07-09 |
Alios Biopharma Inc. |
Protected nucleotide analogs
|
|
TW200942243A
(en)
|
2008-03-05 |
2009-10-16 |
Biocryst Pharm Inc |
Antiviral therapeutic agents
|
|
WO2009129120A2
(en)
|
2008-04-15 |
2009-10-22 |
Rfs Pharma, Llc |
Nucleoside derivatives for treatment of caliciviridae infections, including norovirus infections
|
|
AU2009240630B2
(en)
|
2008-04-23 |
2013-07-18 |
Gilead Sciences, Inc. |
Carba-nucleoside analogs for antiviral treatment
|
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
|
AR072428A1
(es)
|
2008-07-01 |
2010-08-25 |
Medivir Ab |
Derivados de pirimidin nucleotidos inhibidores de polimerasas del virus de la hepatitis c (vhc), composiciones farmaceuticas que los contienen y metodo para prepararlos.
|
|
EP2313102A2
(en)
|
2008-07-03 |
2011-04-27 |
Biota Scientific Management |
Bycyclic nucleosides and nucleotides as therapeutic agents
|
|
US8470834B2
(en)
|
2008-08-20 |
2013-06-25 |
Merck Sharp & Dohme Corp. |
AZO-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
AU2009282571B2
(en)
|
2008-08-20 |
2014-12-11 |
Merck Sharp & Dohme Corp. |
Ethynyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
CA2734486A1
(en)
|
2008-08-20 |
2010-02-25 |
Southern Research Institute |
Substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
TW201020238A
(en)
|
2008-08-20 |
2010-06-01 |
Schering Corp |
Ethenyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
PA8852101A1
(es)
|
2008-12-08 |
2010-07-27 |
Medivir Ab |
Nucleótidos uracil ciclopropílicos
|
|
US8815829B2
(en)
|
2008-12-09 |
2014-08-26 |
Rfs Pharma, Llc |
3′-azido purine nucleotide prodrugs for treatment of viral infections
|
|
US8551973B2
(en)
*
|
2008-12-23 |
2013-10-08 |
Gilead Pharmasset Llc |
Nucleoside analogs
|
|
EP2376515A1
(en)
|
2008-12-23 |
2011-10-19 |
Pharmasset, Inc. |
Synthesis of purine nucleosides
|
|
CA2748057C
(en)
*
|
2008-12-23 |
2018-07-03 |
Pharmasset, Inc. |
Nucleoside phosphoramidates
|
|
KR20110120886A
(ko)
|
2009-01-09 |
2011-11-04 |
유니버시티 칼리지 오브 카디프 컨설턴트 리미티드 |
바이러스 감염 치료용 구아노신 뉴클레오사이드 화합물의 포스포라미데이트 유도체
|
|
KR101774429B1
(ko)
|
2009-02-06 |
2017-09-04 |
코크리스탈 파마, 아이엔씨. |
암 및 바이러스 감염 치료용 퓨린 뉴클레오시드 모노포스페이트 프로드럭
|
|
PE20161067A1
(es)
|
2009-02-10 |
2016-10-23 |
Gilead Sciences Inc |
Analogos carba-nucleosidicos para tratamiento antiviral
|
|
AR075584A1
(es)
|
2009-02-27 |
2011-04-20 |
Intermune Inc |
COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO.
|
|
WO2010101967A2
(en)
|
2009-03-04 |
2010-09-10 |
Idenix Pharmaceuticals, Inc. |
Phosphothiophene and phosphothiazole hcv polymerase inhibitors
|
|
WO2010108135A1
(en)
|
2009-03-20 |
2010-09-23 |
Alios Biopharma, Inc. |
Protected nucleotide analogs
|
|
MX2011009728A
(es)
|
2009-03-20 |
2011-10-14 |
Alios Biopharma Inc |
Analogos nucleotido y nucleosido sustituidos.
|
|
JO3027B1
(ar)
|
2009-05-14 |
2016-09-05 |
Janssen Products Lp |
نيوكليوسيدات يوراسيل سبيرواوكسيتان
|
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
|
TWI598358B
(zh)
|
2009-05-20 |
2017-09-11 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
|
EP2264169A1
(en)
|
2009-06-15 |
2010-12-22 |
Qiagen GmbH |
Modified siNA
|
|
WO2011005595A2
(en)
|
2009-06-24 |
2011-01-13 |
Alios Biopharma, Inc. |
2-5a analogs and their methods of use
|
|
WO2011005860A2
(en)
|
2009-07-07 |
2011-01-13 |
Alnylam Pharmaceuticals, Inc. |
5' phosphate mimics
|
|
US7973013B2
(en)
|
2009-09-21 |
2011-07-05 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
US8455451B2
(en)
|
2009-09-21 |
2013-06-04 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
BR112012007122A2
(pt)
|
2009-09-29 |
2016-07-12 |
Janssen Products Lp |
derivados de fosforamidatos de nucleosídeos
|
|
US8816074B2
(en)
|
2009-11-16 |
2014-08-26 |
University of Georgia Foundation, Inc. |
2′-fluoro-6′-methylene carbocyclic nucleosides and methods of treating viral infections
|
|
EP2501709A4
(en)
|
2009-11-16 |
2013-11-13 |
Univ Georgia |
2'-FLUOR-6'-METHYLENE CARBOXYCLIC NUCLEOSIDES AND METHOD FOR THE TREATMENT OF VIRUS INFECTIONS THEREWITH
|
|
AR079528A1
(es)
|
2009-12-18 |
2012-02-01 |
Idenix Pharmaceuticals Inc |
Inhibidores de arileno o heteroarileno 5,5-fusionado del virus de la hepatitis c
|
|
PL3290428T3
(pl)
|
2010-03-31 |
2022-02-07 |
Gilead Pharmasset Llc |
Tabletka zawierająca krystaliczny (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-diokso-3,4-dihydropirymidyn-1(2H)-ylo)-4-fluoro-3-hydroksy-4-metylotetrahydrofuran-2-ylo)metoksy)(fenoksy)fosforylo)amino)propanian izopropylu
|
|
CL2011000718A1
(es)
|
2010-03-31 |
2012-04-09 |
Gilead Pharmasset Llc |
Proceso para la preparacion de compuestos fosforados enantiomericos.
|
|
US8680071B2
(en)
|
2010-04-01 |
2014-03-25 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
TW201201815A
(en)
|
2010-05-28 |
2012-01-16 |
Gilead Sciences Inc |
1'-substituted-carba-nucleoside prodrugs for antiviral treatment
|
|
WO2012012465A1
(en)
|
2010-07-19 |
2012-01-26 |
Clarke, Michael, O'neil Hanrahan |
Methods for the preparation of diasteromerically pure phosphoramidate prodrugs
|
|
US8859595B2
(en)
|
2010-08-26 |
2014-10-14 |
Rfs Pharma, Llc |
Potent and selective inhibitors of hepatitis C virus
|
|
AU2011305652B2
(en)
|
2010-09-22 |
2016-10-20 |
Janssen Biopharma, Inc. |
Azido nucleosides and nucleotide analogs
|
|
WO2012040126A1
(en)
|
2010-09-22 |
2012-03-29 |
Alios Biopharma, Inc. |
Substituted nucleotide analogs
|
|
EA025341B1
(ru)
|
2010-09-22 |
2016-12-30 |
Алиос Биофарма, Инк. |
Замещенные аналоги нуклеотидов
|
|
AR083221A1
(es)
|
2010-09-29 |
2013-02-06 |
Univ Nac Quilmes |
Proceso para producir dialquilfosfotriesteres de nucleosidos mediante transesterificacion enzimatica y desproteccion de los mismos para producir nucleosidos monofosfato
|
|
WO2012048013A2
(en)
|
2010-10-06 |
2012-04-12 |
Inhibitex, Inc. |
Phosphorodiamidate derivatives of guanosine nucleoside compounds for treatment of viral injections
|
|
US9012428B2
(en)
|
2010-11-10 |
2015-04-21 |
Janssen Products, Lp |
Uracyl spirooxetane nucleoside phosphoramidates
|
|
PT3042910T
(pt)
|
2010-11-30 |
2019-04-16 |
Gilead Pharmasset Llc |
2'-espiro-nucleósidos para utilização na terapia da hepatite c
|
|
WO2012087596A1
(en)
*
|
2010-12-20 |
2012-06-28 |
Gilead Sciences, Inc. |
Combinations for treating hcv
|
|
EP2655392B1
(en)
|
2010-12-22 |
2018-04-18 |
Alios Biopharma, Inc. |
Cyclic nucleotide analogs
|
|
EP2658857B1
(en)
|
2010-12-29 |
2016-11-02 |
Inhibitex, Inc. |
Substituted purine nucleosides, phosphoroamidate and phosphorodiamidate derivatives for treatment of viral infections
|
|
WO2012094248A1
(en)
|
2011-01-03 |
2012-07-12 |
Nanjing Molecular Research, Inc. |
O-(substituted benzyl) phosphoramidate compounds and therapeutic use
|
|
US9085599B2
(en)
|
2011-03-16 |
2015-07-21 |
Enanta Pharmaceuticals, Inc. |
2′allene-substituted nucleoside derivatives
|
|
EP2691409B1
(en)
|
2011-03-31 |
2018-02-21 |
Idenix Pharmaceuticals LLC. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
WO2012142523A2
(en)
|
2011-04-13 |
2012-10-18 |
Gilead Sciences, Inc. |
1'-substituted pyrimidine n-nucleoside analogs for antiviral treatment
|
|
EA201391519A1
(ru)
|
2011-04-13 |
2014-03-31 |
Мерк Шарп И Доум Корп. |
2'-замещенные нуклеозидные производные и способы их применения для лечения вирусных заболеваний
|
|
US9156872B2
(en)
|
2011-04-13 |
2015-10-13 |
Merck Sharp & Dohme Corp. |
2′-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
WO2012158811A2
(en)
|
2011-05-19 |
2012-11-22 |
Rfs Pharma, Llc |
Purine monophosphate prodrugs for treatment of viral infections
|
|
EP2731433A4
(en)
|
2011-07-13 |
2014-12-31 |
Merck Sharp & Dohme |
5'-SUBSTITUTED NUCLEOSIDE ANALOGA AND METHOD FOR THEIR USE FOR THE TREATMENT OF VIRUS DISEASES
|
|
WO2013019874A1
(en)
|
2011-08-01 |
2013-02-07 |
Mbc Pharma, Inc. |
Vitamin b6 derivatives of nucleotides, acyclonucleotides and acyclonucleoside phosphonates
|
|
JP2014526474A
(ja)
|
2011-09-12 |
2014-10-06 |
アイディニックス ファーマシューティカルズ インコーポレイテッド |
ウイルス感染の治療のための化合物および薬学的組成物
|
|
AR088441A1
(es)
|
2011-09-12 |
2014-06-11 |
Idenix Pharmaceuticals Inc |
Compuestos de carboniloximetilfosforamidato sustituido y composiciones farmaceuticas para el tratamiento de infecciones virales
|
|
WO2013044030A1
(en)
|
2011-09-23 |
2013-03-28 |
Enanta Pharmaceuticals, Inc. |
2'-chloroacetylenyl substituted nucleoside derivatives
|
|
EP2768838A1
(en)
|
2011-10-14 |
2014-08-27 |
IDENIX Pharmaceuticals, Inc. |
Substituted 3',5'-cyclic phosphates of purine nucleotide compounds and pharmaceutical compositions for the treatment of viral infections
|
|
EP3556749B1
(en)
|
2011-10-19 |
2023-10-04 |
Mercator Medsystems, Inc. |
Localized modulation of tissues and cells to enhance therapeutic effects including renal denervation
|
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
|
WO2013090420A2
(en)
|
2011-12-12 |
2013-06-20 |
Catabasis Pharmaceuticals, Inc. |
Fatty acid antiviral conjugates and their uses
|
|
GB2497580A
(en)
|
2011-12-16 |
2013-06-19 |
Intercede Ltd |
Data transmission using a plurality of barcodes displayed in a loop
|
|
US8980865B2
(en)
|
2011-12-22 |
2015-03-17 |
Alios Biopharma, Inc. |
Substituted nucleotide analogs
|
|
AU2013221571A1
(en)
|
2012-02-14 |
2014-08-28 |
University Of Georgia Research Foundation, Inc. |
Spiro [2.4] heptanes for treatment of Flaviviridae infections
|
|
EA025358B1
(ru)
*
|
2012-02-27 |
2016-12-30 |
Бристол-Майерс Сквибб Компани |
N-(5S,6S,9R)-5-АМИНО-6-(2,3-ДИФТОРФЕНИЛ)-6,7,8,9-ТЕТРАГИДРО-5H-ЦИКЛОГЕПТА[b]ПИРИДИН-9-ИЛ-4-(2-ОКСО-2,3-ДИГИДРО-1H-ИМИДАЗО[4,5-b]ПИРИДИН-1-ИЛ)ПИПЕРИДИН-1-КАРБОКСИЛАТНАЯ СОЛЬ
|
|
EP2828278A4
(en)
|
2012-03-21 |
2015-12-09 |
Alios Biopharma Inc |
PROCESSES FOR PREPARING SUBSTITUTED NUCLEOTIDE ANALOGS
|
|
WO2013142159A1
(en)
|
2012-03-21 |
2013-09-26 |
Alios Biopharma, Inc. |
Pharmaceutical combinations comprising a thionucleotide analog
|
|
HK1203356A1
(en)
|
2012-03-22 |
2015-10-30 |
艾丽奥斯生物制药有限公司 |
Pharmaceutical combinations comprising a thionucleotide analog
|
|
US20150057243A1
(en)
|
2012-04-02 |
2015-02-26 |
Northern University |
Compositions and Methods for the Inhibition of Methyltransferases
|
|
US8846638B2
(en)
|
2012-05-17 |
2014-09-30 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic nucleoside phosphoramidate derivatives
|
|
US9109001B2
(en)
|
2012-05-22 |
2015-08-18 |
Idenix Pharmaceuticals, Inc. |
3′,5′-cyclic phosphoramidate prodrugs for HCV infection
|
|
GEP20176800B
(en)
|
2012-05-22 |
2018-01-10 |
Idenix Pharmaceuticals Llk |
D-amino acid compounds for liver disease
|
|
CN104640444B
(zh)
|
2012-06-16 |
2016-12-14 |
河南美泰宝生物制药有限公司 |
双肝脏靶向氨基磷酸酯和氨基膦酸酯前药
|
|
CN104583224A
(zh)
|
2012-07-03 |
2015-04-29 |
百时美施贵宝公司 |
制备用于治疗病毒感染的核苷化合物的富含非对映体的氨基磷酸酯衍生物的方法
|
|
WO2014047117A1
(en)
|
2012-09-18 |
2014-03-27 |
Bristol-Myers Squibb Company |
Process for preparing phosphoramidate derivatives of nucleoside compounds for treatment of viral infections
|
|
EP2900682A1
(en)
|
2012-09-27 |
2015-08-05 |
IDENIX Pharmaceuticals, Inc. |
Esters and malonates of sate prodrugs
|
|
WO2014063019A1
(en)
|
2012-10-19 |
2014-04-24 |
Idenix Pharmaceuticals, Inc. |
Dinucleotide compounds for hcv infection
|
|
RU2015119999A
(ru)
|
2012-10-29 |
2016-12-20 |
Кокристал Фарма, Инк. |
Пиримидиновые нуклеозиды и их монофосфатные пролекарства для лечения вырусных инфекций и рака
|
|
ES2725491T3
(es)
|
2012-11-16 |
2019-09-24 |
Univ College Cardiff Consultants Ltd |
Mezcla de RP/SP gemcitabina-[fenil-(benciloxi-L-alaninil)]-fosfato
|
|
GB201220843D0
(en)
|
2012-11-20 |
2013-01-02 |
Univ College Cork Nat Univ Ie |
Compound
|
|
US20140205566A1
(en)
|
2012-11-30 |
2014-07-24 |
Novartis Ag |
Cyclic nucleuoside derivatives and uses thereof
|
|
US9211300B2
(en)
|
2012-12-19 |
2015-12-15 |
Idenix Pharmaceuticals Llc |
4′-fluoro nucleosides for the treatment of HCV
|
|
WO2014100498A1
(en)
|
2012-12-21 |
2014-06-26 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
CN110684067A
(zh)
|
2012-12-21 |
2020-01-14 |
艾丽奥斯生物制药有限公司 |
取代的核苷和核苷酸
|
|
MY172166A
(en)
|
2013-01-31 |
2019-11-15 |
Gilead Pharmasset Llc |
Combination formulation of two antiviral compounds
|
|
WO2014124430A1
(en)
|
2013-02-11 |
2014-08-14 |
Emory University |
Nucleotide and nucleoside therapeutic compositions and uses related thereto
|
|
US9339541B2
(en)
|
2013-03-04 |
2016-05-17 |
Merck Sharp & Dohme Corp. |
Thiophosphate nucleosides for the treatment of HCV
|
|
US9187515B2
(en)
|
2013-04-01 |
2015-11-17 |
Idenix Pharmaceuticals Llc |
2′,4′-fluoro nucleosides for the treatment of HCV
|
|
WO2014169278A1
(en)
|
2013-04-12 |
2014-10-16 |
Achillion Pharmaceuticals, Inc. |
Highly active nucleoside derivative for the treatment of hcv
|
|
CN103435672A
(zh)
|
2013-04-25 |
2013-12-11 |
刘沛 |
含有取代苄基的新型核苷磷酸酯前药的结构与合成
|
|
US9815864B2
(en)
|
2013-06-26 |
2017-11-14 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
WO2015002952A1
(en)
|
2013-07-02 |
2015-01-08 |
Abbvie Inc. |
Methods for treating hcv
|
|
EP3043803B1
(en)
|
2013-09-11 |
2022-04-27 |
Emory University |
Nucleotide and nucleoside compositions and their uses
|
|
AU2014331863C1
(en)
|
2013-10-11 |
2019-05-16 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
US8889701B1
(en)
|
2013-10-11 |
2014-11-18 |
Alla Chem, Llc |
Substituted (S)-(2R,3R,5R)-3-hydroxy-(5-pyrimidin-1-yl)tetrahydrofuran-2-ylmethyl aryl phosphoramidate
|
|
WO2015061683A1
(en)
|
2013-10-25 |
2015-04-30 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate and d-alanine thiophosphoramidate pronucleotides of nucleoside compounds useful for the treatment of hcv
|
|
EP3063165A1
(en)
*
|
2013-11-01 |
2016-09-07 |
Idenix Pharmaceuticals LLC |
D-alanine phosphoramidate pronucleotides of 2'-methyl 2'-fluoro guanosine nucleoside compounds for the treatment of hcv
|
|
KR20160099090A
(ko)
|
2013-11-27 |
2016-08-19 |
아이데닉스 파마슈티칼스 엘엘씨 |
간암의 치료를 위한 뉴클레오티드
|
|
WO2015084741A2
(en)
|
2013-12-02 |
2015-06-11 |
Gilead Pharmasset Llc |
Methods of treating hepatitis c virus infection in subjects with cirrhosis
|
|
WO2015095305A1
(en)
|
2013-12-17 |
2015-06-25 |
Idenix Pharmaceuticals, Inc. |
Production of cyclic phosphate, phosphoramidate, thiophosphate, and phosphonate nucleoside compounds
|
|
WO2015158913A1
(en)
|
2014-04-17 |
2015-10-22 |
Katholieke Universiteit Leuven |
Novel antiviral and antitumoral compounds
|
|
CN117379452A
(zh)
|
2014-06-24 |
2024-01-12 |
艾丽奥斯生物制药有限公司 |
取代的核苷、核苷酸和其类似物
|
|
AU2015280234B2
(en)
|
2014-06-24 |
2021-04-01 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
WO2016041877A1
(en)
|
2014-09-15 |
2016-03-24 |
Medivir Ab |
Methods for the preparation of diastereomerically pure phosphoramidate prodrugs
|
|
CN105646629A
(zh)
|
2014-11-25 |
2016-06-08 |
广州市恒诺康医药科技有限公司 |
L-核苷类化合物及其应用
|
|
MA41441A
(fr)
|
2014-12-19 |
2017-12-12 |
Alios Biopharma Inc |
Nucléosides substitués, nucléotides et analogues de ceux-ci
|
|
MA41213A
(fr)
|
2014-12-19 |
2017-10-24 |
Alios Biopharma Inc |
Nucléosides substitués, nucléotides et analogues de ceux-ci
|
|
GEAP202215528A
(en)
|
2015-03-06 |
2022-11-10 |
Atea Pharmaceuticals Inc |
B-D-2'-DEOXY-2'a-FLUORO-2'-B-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT
|
|
WO2016145142A1
(en)
|
2015-03-10 |
2016-09-15 |
Emory University |
Nucleotide and nucleoside therapeutics compositions and uses related thereto
|
|
CN106188192B
(zh)
|
2015-04-29 |
2019-09-10 |
刘沛 |
含d-氨基酸酯的核苷氨基磷酸/膦酸酯衍生物及其医药用途
|
|
WO2018009623A1
(en)
|
2016-07-08 |
2018-01-11 |
Atea Pharmaceuticals, Inc. |
β-D-2'-DEOXY-2'-SUBSTITUTED-4'-SUBSTITUTED-2-SUBSTITUTED-N6-SUBSTITUTED-6-AMINOPURINE NUCLEOTIDES FOR THE TREATMENT OF PARAMYXOVIRUS AND ORTHOMYXOVIRUS INFECTIONS
|
|
US10202412B2
(en)
|
2016-07-08 |
2019-02-12 |
Atea Pharmaceuticals, Inc. |
β-D-2′-deoxy-2′-substituted-4′-substituted-2-substituted-N6-substituted-6-aminopurinenucleotides for the treatment of paramyxovirus and orthomyxovirus infections
|
|
LU100724B1
(en)
|
2016-07-14 |
2018-07-31 |
Atea Pharmaceuticals Inc |
Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection
|
|
BR112019004297A2
(pt)
|
2016-09-07 |
2019-05-28 |
Atea Pharmaceuticals Inc |
método, uso de uma quantidade eficaz de um composto, composto, e, composição farmacêutica.
|
|
SG11201906163TA
(en)
*
|
2017-02-01 |
2019-08-27 |
Atea Pharmaceuticals Inc |
Nucleotide hemi-sulfate salt for the treatment of hepatitis c virus
|
|
EP3773753A4
(en)
|
2018-04-10 |
2021-12-22 |
ATEA Pharmaceuticals, Inc. |
TREATMENT OF PATIENTS INFECTED WITH THE HEPATITIS C VIRUS WITH CIRRHOSIS
|
|
US10874687B1
(en)
|
2020-02-27 |
2020-12-29 |
Atea Pharmaceuticals, Inc. |
Highly active compounds against COVID-19
|
|
WO2021216722A1
(en)
|
2020-04-23 |
2021-10-28 |
Atea Pharmaceuticals, Inc. |
Stereoselective process of manufacture of purine phosphoramidates
|
|
AU2021327241A1
(en)
|
2020-08-19 |
2023-04-20 |
Atea Pharmaceuticals, Inc. |
Stereoselective manufacture of selected purine phosphoramidates
|
|
CA3173701A1
(en)
|
2020-10-09 |
2022-04-14 |
Jean-Pierre Sommadossi |
Niran interfering drugs for sars-cov-2 mutant therapy
|
|
AU2022213335A1
(en)
|
2021-01-26 |
2023-07-27 |
Atea Pharmaceuticals, Inc. |
Advantageous morphic form of at-527 hemi-sulfate salt
|