JP2022552881A5 - - Google Patents
Info
- Publication number
- JP2022552881A5 JP2022552881A5 JP2022523519A JP2022523519A JP2022552881A5 JP 2022552881 A5 JP2022552881 A5 JP 2022552881A5 JP 2022523519 A JP2022523519 A JP 2022523519A JP 2022523519 A JP2022523519 A JP 2022523519A JP 2022552881 A5 JP2022552881 A5 JP 2022552881A5
- Authority
- JP
- Japan
- Prior art keywords
- day
- pharmaceutical composition
- cycle
- approximately
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962923955P | 2019-10-21 | 2019-10-21 | |
| US62/923,955 | 2019-10-21 | ||
| US202063011147P | 2020-04-16 | 2020-04-16 | |
| US63/011,147 | 2020-04-16 | ||
| PCT/US2020/056409 WO2021080936A1 (en) | 2019-10-21 | 2020-10-20 | Methods of treating chronic lymphocytic leukemia using 2-(2,6-dioxopiperidin-3yl)-4-((2-fluoro-4-((3-morpholinoazetidin-1-yl)methyl)benzyl)amino)isoindoline-1. 3-dione |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022552881A JP2022552881A (ja) | 2022-12-20 |
| JP2022552881A5 true JP2022552881A5 (enExample) | 2023-10-20 |
| JP7581345B2 JP7581345B2 (ja) | 2024-11-12 |
Family
ID=73452273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022523519A Active JP7581345B2 (ja) | 2019-10-21 | 2020-10-20 | ２－（２，６－ジオキソピペリジン－３－イル）－４－（（２－フルオロ－４－（（３－モルホリノアゼチジン－１－イル）メチル）ベンジル）アミノ）イソインドリン－１，３－ジオンを用いて慢性リンパ性白血病を治療する方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11628172B2 (enExample) |
| EP (1) | EP4048279B1 (enExample) |
| JP (1) | JP7581345B2 (enExample) |
| KR (1) | KR20220103953A (enExample) |
| CN (2) | CN114885603A (enExample) |
| AU (1) | AU2020369497C1 (enExample) |
| CA (1) | CA3154510A1 (enExample) |
| CL (1) | CL2022000991A1 (enExample) |
| ES (1) | ES3066029T3 (enExample) |
| IL (1) | IL292265B2 (enExample) |
| MX (1) | MX2022004727A (enExample) |
| WO (1) | WO2021080936A1 (enExample) |
| ZA (1) | ZA202204446B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020369497C1 (en) * | 2019-10-21 | 2026-05-07 | Celgene Corporation | Methods of treating chronic lymphocytic leukemia using 2-(2,6-dioxopiperidin-3yl)-4-((2-fluoro-4-((3-morpholinoazetidin-1-yl)methyl)benzyl)amino)isoindoline-1. 3-dione |
| IL292375A (en) | 2019-10-21 | 2022-06-01 | Celgene Corp | Solid forms include (s)-2-(2,6-dioxopiperidin-3-yl)-4-((2-fluoro-4-((3-morpholinoazetidin-1-yl)metyl)benzyl)amino)isoindoline-1 3- Discussion and salts from them, and preparations that include the same and their use |
| AU2020372333B2 (en) * | 2019-10-21 | 2026-08-06 | Celgene Corporation | Methods for treating a hematological cancer and the use of companion biomarkers for 2-(2,6-Dioxopiperidin-3-yl)-4-((2-fluoro-4-((3-morpholinoazetidin-1-yl)methyl)benzyl)amino)isoindoline-1,3-dione |
| SMT202600194T1 (it) | 2019-10-21 | 2026-05-12 | Celgene Corp | Combinazione di composti di 4-amminoisoindolin-1,3-dione sostituiti e di secondi agenti attivi per l'uso nel trattamento di una condizione maligna ematologica |
| HRP20231487T1 (hr) | 2019-10-21 | 2024-03-01 | Celgene Corporation | Postupci za liječenje hematoloških malignosti uporabom 2-(2,6-dioksopiperidin-3-il)-4-((2-fluoro-4-((3-morfolinoazetidin-1-il)metil)benzil)amino)izoindolin-1,3-diona |
| CN114885602A (zh) * | 2019-10-21 | 2022-08-09 | 新基公司 | 包含(s)-2-(2,6-二氧代哌啶-3-基)-4-((2-氟-4-((3-吗啉代氮杂环丁烷-1-基)甲基)苄基)氨基)异吲哚啉-1,3-二酮的药物组合物及其使用方法 |
| WO2026099206A1 (en) | 2024-11-05 | 2026-05-15 | Celgene Corporation | Therapy for the treatment of non-hodgkin lymphoma |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8648096B2 (en) | 2006-09-15 | 2014-02-11 | Celgene Corporation | N-methylaminomethyl isoindole compounds and compositions comprising and methods of using the same |
| MX380504B (es) | 2010-06-03 | 2025-03-12 | Pharmacyclics Llc | El uso de inhibidores de la tirosina quinasa de bruton (btk). |
| EP2981262A1 (en) | 2013-04-02 | 2016-02-10 | Celgene Corporation | Methods and compositions using 4-amino-2-(2,6-dioxo-piperidine-3-yl)-isoindoline-1,3-dione for treatment and management of central nervous system cancers |
| US20170128448A1 (en) | 2014-07-11 | 2017-05-11 | Celgene Corporation | Combination therapy for cancer |
| CN118344338A (zh) | 2018-04-23 | 2024-07-16 | 细胞基因公司 | 取代的4-氨基异吲哚啉-1,3-二酮化合物以及它们用于治疗淋巴瘤的用途 |
| AR119715A1 (es) | 2019-04-12 | 2022-01-05 | Celgene Corp | Métodos para tratar linfoma no hodgkin con el uso de 2-(2,6-dioxopiperidin-3-il)-4-((2-fluoro-4-((3-morfolinoazetidin-1-il)metil)bencil)amino)isoindolin-1,3-diona |
| AU2020369497C1 (en) * | 2019-10-21 | 2026-05-07 | Celgene Corporation | Methods of treating chronic lymphocytic leukemia using 2-(2,6-dioxopiperidin-3yl)-4-((2-fluoro-4-((3-morpholinoazetidin-1-yl)methyl)benzyl)amino)isoindoline-1. 3-dione |
| AU2020372333B2 (en) * | 2019-10-21 | 2026-08-06 | Celgene Corporation | Methods for treating a hematological cancer and the use of companion biomarkers for 2-(2,6-Dioxopiperidin-3-yl)-4-((2-fluoro-4-((3-morpholinoazetidin-1-yl)methyl)benzyl)amino)isoindoline-1,3-dione |
| SMT202600194T1 (it) * | 2019-10-21 | 2026-05-12 | Celgene Corp | Combinazione di composti di 4-amminoisoindolin-1,3-dione sostituiti e di secondi agenti attivi per l'uso nel trattamento di una condizione maligna ematologica |
| HRP20231487T1 (hr) | 2019-10-21 | 2024-03-01 | Celgene Corporation | Postupci za liječenje hematoloških malignosti uporabom 2-(2,6-dioksopiperidin-3-il)-4-((2-fluoro-4-((3-morfolinoazetidin-1-il)metil)benzil)amino)izoindolin-1,3-diona |
| CN114885602A (zh) | 2019-10-21 | 2022-08-09 | 新基公司 | 包含(s)-2-(2,6-二氧代哌啶-3-基)-4-((2-氟-4-((3-吗啉代氮杂环丁烷-1-基)甲基)苄基)氨基)异吲哚啉-1,3-二酮的药物组合物及其使用方法 |
-
2020
- 2020-10-20 AU AU2020369497A patent/AU2020369497C1/en active Active
- 2020-10-20 KR KR1020227016738A patent/KR20220103953A/ko active Pending
- 2020-10-20 ES ES20807936T patent/ES3066029T3/es active Active
- 2020-10-20 EP EP20807936.8A patent/EP4048279B1/en active Active
- 2020-10-20 JP JP2022523519A patent/JP7581345B2/ja active Active
- 2020-10-20 IL IL292265A patent/IL292265B2/en unknown
- 2020-10-20 WO PCT/US2020/056409 patent/WO2021080936A1/en not_active Ceased
- 2020-10-20 US US17/075,125 patent/US11628172B2/en active Active
- 2020-10-20 MX MX2022004727A patent/MX2022004727A/es unknown
- 2020-10-20 CN CN202080088934.9A patent/CN114885603A/zh active Pending
- 2020-10-20 CN CN202310077726.4A patent/CN115919870B/zh active Active
- 2020-10-20 CA CA3154510A patent/CA3154510A1/en active Pending
-
2022
- 2022-04-20 ZA ZA2022/04446A patent/ZA202204446B/en unknown
- 2022-04-20 CL CL2022000991A patent/CL2022000991A1/es unknown
-
2023
- 2023-03-09 US US18/119,679 patent/US20230210859A1/en not_active Abandoned
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