JP2012505836A5 - - Google Patents
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- Publication number
- JP2012505836A5 JP2012505836A5 JP2011531305A JP2011531305A JP2012505836A5 JP 2012505836 A5 JP2012505836 A5 JP 2012505836A5 JP 2011531305 A JP2011531305 A JP 2011531305A JP 2011531305 A JP2011531305 A JP 2011531305A JP 2012505836 A5 JP2012505836 A5 JP 2012505836A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- benzofuran
- oxadiazol
- diol
- propane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2008905369A AU2008905369A0 (en) | 2008-10-17 | S1P Receptors Modulators and Their use Thereof | |
| AU2008905369 | 2008-10-17 | ||
| AU2009903644 | 2009-08-05 | ||
| AU2009903644A AU2009903644A0 (en) | 2009-08-05 | S1P Receptors Modulators and their use Thereof | |
| PCT/AU2009/001371 WO2010043000A1 (en) | 2008-10-17 | 2009-10-19 | S1p receptors modulators and their use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014192502A Division JP5963823B2 (ja) | 2008-10-17 | 2014-09-22 | S1p受容体モジュレーターおよびそれらの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012505836A JP2012505836A (ja) | 2012-03-08 |
| JP2012505836A5 true JP2012505836A5 (enExample) | 2013-02-07 |
Family
ID=42106136
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011531305A Pending JP2012505836A (ja) | 2008-10-17 | 2009-10-19 | S1p受容体モジュレーターおよびそれらの使用 |
| JP2014192502A Expired - Fee Related JP5963823B2 (ja) | 2008-10-17 | 2014-09-22 | S1p受容体モジュレーターおよびそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014192502A Expired - Fee Related JP5963823B2 (ja) | 2008-10-17 | 2014-09-22 | S1p受容体モジュレーターおよびそれらの使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US8592399B2 (enExample) |
| EP (1) | EP2344484B1 (enExample) |
| JP (2) | JP2012505836A (enExample) |
| CN (1) | CN102186845B (enExample) |
| AU (1) | AU2009304598B2 (enExample) |
| CA (1) | CA2740484C (enExample) |
| ES (1) | ES2590904T3 (enExample) |
| NZ (1) | NZ592748A (enExample) |
| WO (1) | WO2010043000A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2009304596A1 (en) | 2008-10-17 | 2010-04-22 | Akaal Pharma Pty Ltd | S1P receptors modulators |
| WO2010043000A1 (en) | 2008-10-17 | 2010-04-22 | Akaal Pharma Pty Ltd | S1p receptors modulators and their use thereof |
| PE20120578A1 (es) * | 2009-02-10 | 2012-06-17 | Abbott Lab | Agonistas y antagonistas del receptor de s1p5, y metodos de uso de los mismos |
| ES2675856T3 (es) * | 2010-11-30 | 2018-07-13 | Connora Technologies, Inc. | Agentes nuevos para resinas epóxicas retrabajables |
| EP2697195A1 (en) | 2011-04-14 | 2014-02-19 | Allergan, Inc. | Phenyl bicyclic methyl azetidine derivatives as sphingosine-1 phosphate receptors modulators |
| CN102993027B (zh) * | 2011-09-08 | 2014-08-13 | 中化蓝天集团有限公司 | 4-氟-n-异丙基苯胺的定向单烷基化制备方法 |
| KR101889131B1 (ko) | 2011-12-23 | 2018-09-20 | 메이지 세이카 파루마 가부시키가이샤 | 신규 s1p 수용체 조정제 |
| EP2847177B1 (en) | 2012-05-09 | 2017-10-11 | Boehringer Ingelheim International GmbH | Methods for making oxetan-3-ylmethanamines |
| JP6324380B2 (ja) | 2012-07-27 | 2018-05-16 | バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. | S1p調節剤および/またはatx調節剤である化合物 |
| US8859598B2 (en) * | 2012-10-04 | 2014-10-14 | Allergan, Inc. | 1, 2, 4-oxadiazoles azetidine derivatives as sphingosine-1 phosphate receptors modulators |
| WO2014063199A1 (en) * | 2012-10-26 | 2014-05-01 | Akaal Pharma Pty Ltd | Organic compounds |
| ES2755772T3 (es) | 2012-11-07 | 2020-04-23 | Nerviano Medical Sciences Srl | Pirimidinil y piridinilpirrolopiridinonas sustituidas, proceso para su preparación y su uso como inhibidores de cinasas |
| US8735433B1 (en) * | 2012-11-14 | 2014-05-27 | Allergan, Inc. | Aryl oxadiazole derivatives as sphingosine 1-phosphate (S1P) receptor modulators |
| CN103304499B (zh) * | 2013-06-02 | 2015-03-04 | 张远强 | 抗糖尿病化合物、其制备方法和用途 |
| CN103304503B (zh) * | 2013-06-02 | 2015-03-04 | 张远强 | 抗糖尿病化合物、其制备方法和用途 |
| US20150051186A1 (en) * | 2013-08-15 | 2015-02-19 | Allergan, Inc. | Aryl azetidine derivatives as sphingosine-1 phosphate receptors modulators |
| CN106132928B (zh) * | 2014-02-28 | 2019-03-29 | 橘生药品工业株式会社 | 苯胺衍生物、含有所述衍生物的药物组合物及其用途 |
| US9745253B2 (en) | 2015-03-13 | 2017-08-29 | Forma Therapeutics, Inc. | Alpha-cinnamide compounds and compositions as HDAC8 inhibitors |
| JP2018527406A (ja) * | 2015-08-11 | 2018-09-20 | アカール ファーマ ピーティーワイ リミテッドAkaal Pharma Pty Ltd | S1p受容体モジュレーターを含む組成物 |
| CA3013917A1 (en) | 2016-02-09 | 2017-08-17 | Pharmakea, Inc. | Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof |
| EP4252856A3 (en) | 2016-12-20 | 2024-01-24 | Oligomerix, Inc. | Novel quinazolinones that inhibit the formation of tau oligomers and their method of use |
| EP3562483B1 (en) | 2016-12-20 | 2025-09-03 | Oligomerix, Inc. | Novel benzofuran, benzothiophene, and indole analogs that inhibit the formation of tau oligomers and their method of use |
| JP7252908B2 (ja) | 2017-06-14 | 2023-04-05 | トレベナ・インコーポレイテッド | S1p1活性を調節するための化合物およびその使用法 |
| KR102017324B1 (ko) | 2018-04-30 | 2019-09-02 | 경북대학교 산학협력단 | 신규한 asm 활성 직접 억제 화합물 2-아미노-2-(1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체 및 이의 용도 |
| US11801242B2 (en) | 2018-10-09 | 2023-10-31 | Duke University | Compositions and methods for adjuvant cancer therapeutics |
| WO2020114477A1 (zh) * | 2018-12-06 | 2020-06-11 | 上海济煜医药科技有限公司 | 作为免疫调节剂的化合物及其制备方法和应用 |
| CN109824685B (zh) * | 2019-04-03 | 2021-03-23 | 辽宁中医药大学 | 马齿苋中化合物oleracone G及其提取分离方法与应用 |
| AU2020341464A1 (en) * | 2019-09-05 | 2022-04-21 | Trevena, Inc. | Methods of treating epilepsy using the same |
| MX2022005766A (es) | 2019-11-19 | 2022-08-08 | Trevena Inc | Compuestos y métodos para la preparación de compuestos moduladores de esfingosina 1-fosfato tipo 1 (s1p1). |
| AU2021228371A1 (en) * | 2020-02-28 | 2022-10-13 | Akaal Pharma Pty Ltd | S1P receptor modulators |
| BR112023018676A2 (pt) | 2021-03-18 | 2023-10-10 | Seagen Inc | Conjugado anticorpo-fármaco, composição farmacêutica, métodos de tratamento de uma doença ou condição e de um câncer, e, composição de conjugado ligante-fármaco |
| TW202430514A (zh) | 2022-09-30 | 2024-08-01 | 瑞士商先正達農作物保護股份公司 | 殺微生物之吡唑衍生物 |
| TW202430031A (zh) | 2022-09-30 | 2024-08-01 | 瑞士商先正達農作物保護股份公司 | 殺微生物之吡唑衍生物 |
| WO2024115512A1 (en) | 2022-11-30 | 2024-06-06 | Syngenta Crop Protection Ag | Microbiocidal tetrahydroisoquinoline derivatives |
| WO2025114167A1 (en) | 2023-11-28 | 2025-06-05 | Syngenta Crop Protection Ag | Microbiocidal pyrazole derivatives |
| WO2025191053A1 (en) | 2024-03-14 | 2025-09-18 | Syngenta Crop Protection Ag | Microbiocidal pyrazole derivatives |
| WO2025210095A1 (en) | 2024-04-03 | 2025-10-09 | Syngenta Crop Protection Ag | Microbiocidal tetrahydroisoquinoline compounds |
| WO2025210096A1 (en) | 2024-04-03 | 2025-10-09 | Syngenta Crop Protection Ag | Fungicidal compositions |
| CN118878551B (zh) * | 2024-07-08 | 2026-04-28 | 安徽大学 | 一种4-溴噻吩并[2,3-c]吡啶-2-羧酸乙酯的制备方法 |
Family Cites Families (55)
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| US2550646A (en) | 1947-08-21 | 1951-04-24 | Commercial Solvents Corp | Polyamino alcohols and method for preparing them |
| CA2074933C (en) | 1990-11-30 | 2002-12-03 | Masatoshi Chihiro | Thiazole derivatives as active superoxide radical inhibitors |
| WO1995009159A1 (en) * | 1993-09-28 | 1995-04-06 | Otsuka Pharmaceutical Company, Limited | Quinoxaline derivative as antidiabetic agent |
| FR2719044B1 (fr) * | 1994-04-26 | 1996-05-31 | Cird Galderma | Nouveaux composés bi-aromatiques acétylénés à groupement adamantyle, compositions pharmaceutiques et cosmétiques les contenant et utilisations. |
| US5883106A (en) * | 1994-10-18 | 1999-03-16 | Pfizer Inc. | 5-lipoxygenase inhibitors |
| JP3964478B2 (ja) | 1995-06-30 | 2007-08-22 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬 |
| US6221865B1 (en) | 1995-11-06 | 2001-04-24 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| FR2741876B1 (fr) | 1995-12-01 | 1998-01-09 | Cird Galderma | Composes biaromatiques portant un groupement adamantyl en para, compositions pharmaceutiques et cosmetiques les contenant et utilisations |
| JPH10158192A (ja) * | 1996-10-03 | 1998-06-16 | Eisai Co Ltd | 移植片対宿主疾患(gvhd)の治療および臓器移植時の移植片拒絶反応抑制のための医薬組成物 |
| US6228868B1 (en) * | 1998-07-27 | 2001-05-08 | Abbott Laboratories | Oxazoline antiproliferative agents |
| ES2217882T3 (es) * | 1998-12-18 | 2004-11-01 | Basilea Pharmaceutica Ag | 4-(aminoalcoxy)benzofuranos como inhibidores de n-miristoiltransferasa. |
| EP1250332A1 (en) * | 1999-12-17 | 2002-10-23 | Abbott Laboratories | Inhibitors of interleukin 5 gene expression |
| EP1370546A2 (en) * | 2001-03-16 | 2003-12-17 | Abbott Laboratories | Novel amines as histamine-3 receptor ligands and their therapeutic applications |
| US20040106794A1 (en) * | 2001-04-16 | 2004-06-03 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
| AR037714A1 (es) * | 2001-12-06 | 2004-12-01 | Maxia Pharmaceuticals Inc | Derivados de tiazolidinona y oxazolidinona 2-sustituidos para la inhibicion de fosfatasas y el tratamiento de cancer |
| US6951880B2 (en) * | 2002-05-16 | 2005-10-04 | Genelabs Technologies, Inc. | Aryl and heteroaryl compounds as antibacterial and antifungal agents |
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| BRPI0407658A (pt) * | 2003-02-18 | 2006-02-21 | Kyorin Seiyaku Kk | derivados de ácido aminofosfÈnico, seus sais e hidratos que atuam como moduladores de receptor de s1p e agente farmacêutico |
| MXPA05012459A (es) * | 2003-05-19 | 2006-02-22 | Irm Llc | Compuestos y composiciones inmunosupresoras. |
| KR20110140139A (ko) * | 2003-08-29 | 2011-12-30 | 오노 야꾸힝 고교 가부시키가이샤 | S1p 수용체 결합능을 갖는 화합물 및 그 의약 용도 |
| EP1673078B1 (en) | 2003-10-03 | 2008-05-28 | Merck & Co., Inc. | Benzylether and benzylamino beta-secretase inhibitors for the treatment of alzheimer's disease |
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| FR2887882B1 (fr) * | 2005-07-01 | 2007-09-07 | Sanofi Aventis Sa | Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique |
| BRPI0615133A2 (pt) * | 2005-08-23 | 2011-05-03 | Irm Llc | compostos imunossupressores, composições farmacêuticas contendo os mesmos assim como referido uso |
| JP2007169194A (ja) | 2005-12-21 | 2007-07-05 | Kyorin Pharmaceut Co Ltd | ジオキサフォスフォリナン誘導体とその付加塩及びスフィンゴシン−1−リン酸(s1p1,s1p4)受容体作動薬 |
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| BRPI0720478A2 (pt) | 2006-12-21 | 2014-01-14 | Abbott Laboratoires | Compostos agonistas e antagonistas do receptor esfingosina-1-fosfato |
| WO2008099781A1 (ja) | 2007-02-13 | 2008-08-21 | Kyorin Pharmaceutical Co., Ltd. | アミノアルコール誘導体を有効成分とする脱髄性疾患の治療剤又は予防剤 |
| KR101222412B1 (ko) | 2007-02-15 | 2013-01-15 | 에프. 호프만-라 로슈 아게 | Taar1 리간드로서의 2-아미노옥사졸린 |
| EP2014653A1 (en) * | 2007-06-15 | 2009-01-14 | Bioprojet | Novel dicarboxylic acid derivatives as S1P1 receptor agonists |
| US20090118349A1 (en) | 2007-08-16 | 2009-05-07 | Onco-Pharmakon Incorporated | Bis-alkylating agents and their use in cancer therapy |
| UY31922A (es) * | 2008-06-20 | 2010-01-05 | Glaxo Group Ltd | Compuestos |
| AU2009304596A1 (en) | 2008-10-17 | 2010-04-22 | Akaal Pharma Pty Ltd | S1P receptors modulators |
| WO2010043000A1 (en) | 2008-10-17 | 2010-04-22 | Akaal Pharma Pty Ltd | S1p receptors modulators and their use thereof |
| US20100160369A1 (en) * | 2008-12-04 | 2010-06-24 | Exelixis, Inc. | S1P1 Agonists and Methods of Making And Using |
| US8741923B2 (en) | 2008-12-18 | 2014-06-03 | Merck Serono Sa | Oxadiazole fused heterocyclic derivatives useful for the treatment of multiple sclerosis |
| WO2014063199A1 (en) * | 2012-10-26 | 2014-05-01 | Akaal Pharma Pty Ltd | Organic compounds |
-
2009
- 2009-10-19 WO PCT/AU2009/001371 patent/WO2010043000A1/en not_active Ceased
- 2009-10-19 CA CA2740484A patent/CA2740484C/en active Active
- 2009-10-19 EP EP09820119.7A patent/EP2344484B1/en active Active
- 2009-10-19 US US13/124,549 patent/US8592399B2/en active Active
- 2009-10-19 NZ NZ592748A patent/NZ592748A/xx unknown
- 2009-10-19 JP JP2011531305A patent/JP2012505836A/ja active Pending
- 2009-10-19 ES ES09820119.7T patent/ES2590904T3/es active Active
- 2009-10-19 CN CN200980141188.9A patent/CN102186845B/zh active Active
- 2009-10-19 AU AU2009304598A patent/AU2009304598B2/en active Active
-
2013
- 2013-10-29 US US14/066,276 patent/US9193716B2/en active Active
-
2014
- 2014-09-22 JP JP2014192502A patent/JP5963823B2/ja not_active Expired - Fee Related
-
2015
- 2015-10-22 US US14/920,780 patent/US9707205B2/en active Active
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