JP2012505836A5 - - Google Patents

Download PDF

Info

Publication number
JP2012505836A5
JP2012505836A5 JP2011531305A JP2011531305A JP2012505836A5 JP 2012505836 A5 JP2012505836 A5 JP 2012505836A5 JP 2011531305 A JP2011531305 A JP 2011531305A JP 2011531305 A JP2011531305 A JP 2011531305A JP 2012505836 A5 JP2012505836 A5 JP 2012505836A5
Authority
JP
Japan
Prior art keywords
amino
benzofuran
oxadiazol
diol
propane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011531305A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012505836A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/AU2009/001371 external-priority patent/WO2010043000A1/en
Publication of JP2012505836A publication Critical patent/JP2012505836A/ja
Publication of JP2012505836A5 publication Critical patent/JP2012505836A5/ja
Pending legal-status Critical Current

Links

JP2011531305A 2008-10-17 2009-10-19 Ｓ１ｐ受容体モジュレーターおよびそれらの使用 Pending JP2012505836A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2008905369 2008-10-17
AU2008905369A AU2008905369A0 (en) 2008-10-17 S1P Receptors Modulators and Their use Thereof
AU2009903644 2009-08-05
AU2009903644A AU2009903644A0 (en) 2009-08-05 S1P Receptors Modulators and their use Thereof
PCT/AU2009/001371 WO2010043000A1 (en) 2008-10-17 2009-10-19 S1p receptors modulators and their use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014192502A Division JP5963823B2 (ja) 2008-10-17 2014-09-22 Ｓ１ｐ受容体モジュレーターおよびそれらの使用

Publications (2)

Publication Number Publication Date
JP2012505836A JP2012505836A (ja) 2012-03-08
JP2012505836A5 true JP2012505836A5 (enExample) 2013-02-07

Family

ID=42106136

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011531305A Pending JP2012505836A (ja) 2008-10-17 2009-10-19 Ｓ１ｐ受容体モジュレーターおよびそれらの使用
JP2014192502A Active JP5963823B2 (ja) 2008-10-17 2014-09-22 Ｓ１ｐ受容体モジュレーターおよびそれらの使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014192502A Active JP5963823B2 (ja) 2008-10-17 2014-09-22 Ｓ１ｐ受容体モジュレーターおよびそれらの使用

Country Status (9)

Country Link
US (3) US8592399B2 (enExample)
EP (1) EP2344484B1 (enExample)
JP (2) JP2012505836A (enExample)
CN (1) CN102186845B (enExample)
AU (1) AU2009304598B2 (enExample)
CA (1) CA2740484C (enExample)
ES (1) ES2590904T3 (enExample)
NZ (1) NZ592748A (enExample)
WO (1) WO2010043000A1 (enExample)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009304598B2 (en) * 2008-10-17 2015-01-29 Akaal Pharma Pty Ltd S1P receptors modulators and their use thereof
AU2009304596A1 (en) 2008-10-17 2010-04-22 Akaal Pharma Pty Ltd S1P receptors modulators
US20100216762A1 (en) * 2009-02-10 2010-08-26 Abbott Laboratories Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof
WO2012071896A1 (en) * 2010-11-30 2012-06-07 Wuxi Adessonanotech Co., Limited Novel agents for reworkable epoxy resins
WO2012142268A1 (en) * 2011-04-14 2012-10-18 Allergan, Inc. Phenyl bicyclic methyl azetidine derivatives as sphingosine-1 phosphate receptors modulators
CN102993027B (zh) * 2011-09-08 2014-08-13 中化蓝天集团有限公司 4-氟-n-异丙基苯胺的定向单烷基化制备方法
JP6033791B2 (ja) 2011-12-23 2016-11-30 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 新規ｓ１ｐ受容体調整薬
JP6030752B2 (ja) 2012-05-09 2016-11-24 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング オキセタン−３−イルメタンアミンの製造方法
AU2013295594B2 (en) 2012-07-27 2018-03-29 Biogen Ma Inc. Compounds that are S1P modulating agents and/or ATX modulating agents
US8859598B2 (en) * 2012-10-04 2014-10-14 Allergan, Inc. 1, 2, 4-oxadiazoles azetidine derivatives as sphingosine-1 phosphate receptors modulators
WO2014063199A1 (en) * 2012-10-26 2014-05-01 Akaal Pharma Pty Ltd Organic compounds
ES2755772T3 (es) 2012-11-07 2020-04-23 Nerviano Medical Sciences Srl Pirimidinil y piridinilpirrolopiridinonas sustituidas, proceso para su preparación y su uso como inhibidores de cinasas
US8735433B1 (en) * 2012-11-14 2014-05-27 Allergan, Inc. Aryl oxadiazole derivatives as sphingosine 1-phosphate (S1P) receptor modulators
CN103304503B (zh) * 2013-06-02 2015-03-04 张远强 抗糖尿病化合物、其制备方法和用途
CN103304499B (zh) * 2013-06-02 2015-03-04 张远强 抗糖尿病化合物、其制备方法和用途
WO2015023839A1 (en) * 2013-08-15 2015-02-19 Allergan, Inc. Aryl azetidine derivatives as sphingosine-1 phosphate receptors modulators
KR20160122260A (ko) 2014-02-28 2016-10-21 깃세이 야쿠힌 고교 가부시키가이샤 신규한 아닐린 유도체, 그것을 함유하는 의약 조성물 및 그것들의 용도
MX2017011778A (es) 2015-03-13 2017-12-04 Forma Therapeutics Inc Compuestos y composiciones de alfa-cinamida como inhibidores de histona desacetilasa 8 (hdac8).
WO2017024355A1 (en) * 2015-08-11 2017-02-16 Akaal Pharma Pty Ltd Compositions comprising s1p receptor modulators
ES2880766T3 (es) 2016-02-09 2021-11-25 Pharmakea Inc Inhibidores de quinolinona lisil oxidasa similar al tipo 2 y usos de los mismos
WO2018118791A2 (en) 2016-12-20 2018-06-28 Oligomerix, Inc. Novel quinazolinones that inhibit the formation of tau oligomers and their method of use
JP7273722B2 (ja) * 2016-12-20 2023-05-15 オリゴメリックス インコーポレイテッド タウオリゴマーの形成を阻害する新規ベンゾフラン、ベンゾチオフェン及びインドール類似体並びにそれらの使用方法
CN110831593A (zh) 2017-06-14 2020-02-21 特维娜有限公司 用于调节s1p1活性的化合物及其使用方法
KR102017324B1 (ko) * 2018-04-30 2019-09-02 경북대학교 산학협력단 신규한 asm 활성 직접 억제 화합물 2-아미노-2-(1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체 및 이의 용도
US11801242B2 (en) 2018-10-09 2023-10-31 Duke University Compositions and methods for adjuvant cancer therapeutics
CN113072474A (zh) * 2018-12-06 2021-07-06 上海济煜医药科技有限公司 作为免疫调节剂的化合物及其制备方法和应用
CN109824685B (zh) * 2019-04-03 2021-03-23 辽宁中医药大学 马齿苋中化合物oleracone G及其提取分离方法与应用
KR20220079546A (ko) * 2019-09-05 2022-06-13 트레베나, 인코포레이티드. 간질 치료 방법
US11884655B2 (en) 2019-11-19 2024-01-30 Trevena, Inc. Compounds and methods of preparing compounds S1P1 modulators
WO2021168518A1 (en) * 2020-02-28 2021-09-02 Akaal Pharma Pty Ltd S1p receptor modulators
US12036286B2 (en) 2021-03-18 2024-07-16 Seagen Inc. Selective drug release from internalized conjugates of biologically active compounds
TW202430031A (zh) 2022-09-30 2024-08-01 瑞士商先正達農作物保護股份公司 殺微生物之吡唑衍生物
TW202430514A (zh) 2022-09-30 2024-08-01 瑞士商先正達農作物保護股份公司 殺微生物之吡唑衍生物
EP4626882A1 (en) 2022-11-30 2025-10-08 Syngenta Crop Protection AG Microbiocidal tetrahydroisoquinoline derivatives
WO2025114167A1 (en) 2023-11-28 2025-06-05 Syngenta Crop Protection Ag Microbiocidal pyrazole derivatives
WO2025191053A1 (en) 2024-03-14 2025-09-18 Syngenta Crop Protection Ag Microbiocidal pyrazole derivatives
WO2025210095A1 (en) 2024-04-03 2025-10-09 Syngenta Crop Protection Ag Microbiocidal tetrahydroisoquinoline compounds
WO2025210096A1 (en) 2024-04-03 2025-10-09 Syngenta Crop Protection Ag Fungicidal compositions
CN118878551A (zh) * 2024-07-08 2024-11-01 安徽大学 一种4-溴噻吩并[2,3-c]吡啶-2-羧酸乙酯的制备方法

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2550646A (en) 1947-08-21 1951-04-24 Commercial Solvents Corp Polyamino alcohols and method for preparing them
ES2144403T3 (es) 1990-11-30 2000-06-16 Otsuka Pharma Co Ltd Derivados de tiazol como inhibidores de oxigeno activo.
CA2150345A1 (en) * 1993-09-28 1995-04-06 Makoto Komatsu Quinoxaline derivative as antidiabetic agent
FR2719044B1 (fr) 1994-04-26 1996-05-31 Cird Galderma Nouveaux composés bi-aromatiques acétylénés à groupement adamantyle, compositions pharmaceutiques et cosmétiques les contenant et utilisations.
US5883106A (en) * 1994-10-18 1999-03-16 Pfizer Inc. 5-lipoxygenase inhibitors
JP3964478B2 (ja) * 1995-06-30 2007-08-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬
US6221865B1 (en) * 1995-11-06 2001-04-24 University Of Pittsburgh Inhibitors of protein isoprenyl transferases
FR2741876B1 (fr) 1995-12-01 1998-01-09 Cird Galderma Composes biaromatiques portant un groupement adamantyl en para, compositions pharmaceutiques et cosmetiques les contenant et utilisations
JPH10158192A (ja) * 1996-10-03 1998-06-16 Eisai Co Ltd 移植片対宿主疾患（ｇｖｈｄ）の治療および臓器移植時の移植片拒絶反応抑制のための医薬組成物
US6228868B1 (en) * 1998-07-27 2001-05-08 Abbott Laboratories Oxazoline antiproliferative agents
EP1149094B1 (en) * 1998-12-18 2004-04-21 Basilea Pharmaceutica AG 4-(aminoalkoxy)benzofurans as n-myristoyltransferase inhibitors
WO2001044223A1 (en) 1999-12-17 2001-06-21 Abbott Laboratories Inhibitors of interleukin 5 gene expression
BR0205829A (pt) 2001-03-16 2005-03-08 Abbott Lab Novas aminas como ligantes dos receptores de histamina-3 e suas aplicações terapêuticas
US20040106794A1 (en) * 2001-04-16 2004-06-03 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
AR037714A1 (es) 2001-12-06 2004-12-01 Maxia Pharmaceuticals Inc Derivados de tiazolidinona y oxazolidinona 2-sustituidos para la inhibicion de fosfatasas y el tratamiento de cancer
AU2003302218A1 (en) 2002-05-16 2004-06-18 Genelabs Technologies, Inc Aryl and heteroaryl compounds as antibacterial and antifungal agents
BR0317430A (pt) 2002-12-20 2005-10-25 Pharmacia Corp Compostos inibidores de quinase-2 de proteìna ativada por quinase de proteìna ativada por mitógeno
JP4564918B2 (ja) * 2003-02-18 2010-10-20 杏林製薬株式会社 アミノホスホン酸誘導体とその付加塩及びｓ１ｐ受容体調節剤
PT1638551E (pt) * 2003-05-19 2012-03-28 Irm Llc Compostos e composições imunossuppressores
JP4947406B2 (ja) 2003-08-29 2012-06-06 小野薬品工業株式会社 Ｓ１ｐ受容体結合能を有する化合物およびその医薬用途
ATE396973T1 (de) 2003-10-03 2008-06-15 Merck & Co Inc Benzylether- und benzylamino-beta-sekretase- hemmer zur behandlung von alzheimer-krankheit
TW200538433A (en) * 2004-02-24 2005-12-01 Irm Llc Immunosuppressant compounds and compositiions
EP1778632B1 (en) 2004-06-18 2008-08-20 Biolipox AB Indoles useful in the treatment of inflammation
US20060223866A1 (en) * 2004-08-13 2006-10-05 Praecis Pharmaceuticals, Inc. Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity
WO2006022442A1 (ja) * 2004-08-24 2006-03-02 Santen Pharmaceutical Co., Ltd. ジヒドロオロテートデヒドロゲナーゼ阻害活性を有する新規複素環アミド誘導体
AU2005307818A1 (en) * 2004-11-18 2006-05-26 The Institutes For Pharmaceutical Discovery, Llc Heterocyclylbiphenyl derivates as protein Tyrosine phosphatase inhibitors
JP4874958B2 (ja) * 2005-03-30 2012-02-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピリジン誘導体を含有する抗真菌剤
NZ563522A (en) 2005-04-22 2010-01-29 Daiichi Sankyo Co Ltd Heterocyclic compound with immunosuppressive activity
FR2887882B1 (fr) * 2005-07-01 2007-09-07 Sanofi Aventis Sa Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique
CA2619101A1 (en) 2005-08-23 2007-03-01 Irm Llc Immunosuppressant compounds and compositions
JP2007169194A (ja) 2005-12-21 2007-07-05 Kyorin Pharmaceut Co Ltd ジオキサフォスフォリナン誘導体とその付加塩及びスフィンゴシン−１−リン酸（ｓ１ｐ１，ｓ１ｐ４）受容体作動薬
WO2007076055A2 (en) 2005-12-22 2007-07-05 Entremed, Inc. Compositions and methods comprising proteinase activated receptor antagonists
ES2408318T3 (es) * 2005-12-23 2013-06-20 Glaxosmithkline Llc Inhibidores de azaindol de las cinasas Aurora
CA2641718A1 (en) 2006-02-09 2007-08-16 University Of Virginia Patent Foundation Bicyclic sphingosine 1-phosphate analogs
CA2648303C (en) * 2006-04-03 2014-07-15 Astellas Pharma Inc. 5-[monocyclic(hetero)arylsubstituted-1,2,4-oxadliazol-3-yl]-(fused heteroaryl substituted) compounds and their use as s1p1 agonists
CA2650295C (en) 2006-04-26 2015-12-29 Genentech, Inc. Phosphoinositide 3-kinase inhibitor compounds and pharmaceutical compositions containing them
AR062156A1 (es) * 2006-08-01 2008-10-22 Praecis Pharm Inc Compuestos agonistas y selectivos del receptor s1p-1
US8258150B2 (en) 2006-08-17 2012-09-04 The University Of Chicago Treatment of inflammatory diseases
JP2009269819A (ja) * 2006-08-25 2009-11-19 Asahi Kasei Pharma Kk アミン化合物
AU2007323540A1 (en) * 2006-11-21 2008-05-29 University Of Virginia Patent Foundation Hydrindane analogs having sphingosine 1-phosphate receptor agonist activity
AU2007333243B2 (en) * 2006-12-07 2013-03-14 F. Hoffmann-La Roche Ag Phosphoinositide 3-kinase inhibitor compounds and methods of use
US7888352B2 (en) * 2006-12-07 2011-02-15 Piramed Limited Phosphoinositide 3-kinase inhibitor compounds and methods of use
US8486979B2 (en) * 2006-12-12 2013-07-16 Abbvie Inc. 1,2,4 oxadiazole compounds and methods of use thereof
US20080167286A1 (en) 2006-12-12 2008-07-10 Abbott Laboratories Pharmaceutical compositions and their methods of use
TW200838497A (en) 2006-12-21 2008-10-01 Abbott Lab Sphingosine-1-phosphate receptor agonist and antagonist compounds
JP5198293B2 (ja) 2007-02-13 2013-05-15 杏林製薬株式会社 アミノアルコール誘導体を有効成分とする脱髄性疾患の治療剤又は予防剤
MX2009008465A (es) 2007-02-15 2009-08-20 Hoffmann La Roche Nuevas 2-aminooxazolinas como ligandos de taar1.
EP2014653A1 (en) 2007-06-15 2009-01-14 Bioprojet Novel dicarboxylic acid derivatives as S1P1 receptor agonists
US20090118349A1 (en) 2007-08-16 2009-05-07 Onco-Pharmakon Incorporated Bis-alkylating agents and their use in cancer therapy
US20100010053A1 (en) * 2008-06-20 2010-01-14 Jose Luis Castro Pineiro Compounds
AU2009304598B2 (en) 2008-10-17 2015-01-29 Akaal Pharma Pty Ltd S1P receptors modulators and their use thereof
AU2009304596A1 (en) 2008-10-17 2010-04-22 Akaal Pharma Pty Ltd S1P receptors modulators
US20100160369A1 (en) * 2008-12-04 2010-06-24 Exelixis, Inc. S1P1 Agonists and Methods of Making And Using
JP5855942B2 (ja) * 2008-12-18 2016-02-09 メルク セローノ ソシエテ アノニム 多発性硬化症の治療に有用なオキサジアゾール縮合複素環式誘導体
WO2014063199A1 (en) * 2012-10-26 2014-05-01 Akaal Pharma Pty Ltd Organic compounds

Similar Documents

Publication Publication Date Title
JP2012505836A5 (enExample)
ES2660831T3 (es) Derivados de imidazol condensados útiles como inhibidores de IDO
JP2013508279A5 (enExample)
JP2019526596A5 (enExample)
NZ592748A (en) 2-Amino-(oxadiazol-3-yl)-benzofuran derivatives and their use as S1P receptor modulators
JP2010523522A5 (enExample)
JP2014505107A5 (enExample)
JP2010138190A5 (enExample)
JP2012525393A5 (enExample)
JP2015505296A5 (enExample)
JP2014511892A5 (enExample)
JP2013545730A5 (enExample)
JP2017537158A5 (enExample)
JP2009504763A5 (enExample)
RU2017105470A (ru) Способы лечения парамиксовирусов
JP2019520344A5 (enExample)
JP2010501584A5 (enExample)
JP2016040288A5 (enExample)
JP2008539268A5 (enExample)
JP2014505096A5 (enExample)
JP2014500265A5 (enExample)
JP2013522230A5 (enExample)
JP2015516427A5 (enExample)
JP2019505529A5 (enExample)
RU2010154173A (ru) Режим введения нитрокатехолов