JP2012505836A5 - - Google Patents
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- Publication number
- JP2012505836A5 JP2012505836A5 JP2011531305A JP2011531305A JP2012505836A5 JP 2012505836 A5 JP2012505836 A5 JP 2012505836A5 JP 2011531305 A JP2011531305 A JP 2011531305A JP 2011531305 A JP2011531305 A JP 2011531305A JP 2012505836 A5 JP2012505836 A5 JP 2012505836A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- benzofuran
- oxadiazol
- diol
- propane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2008905369A AU2008905369A0 (en) | 2008-10-17 | S1P Receptors Modulators and Their use Thereof | |
| AU2008905369 | 2008-10-17 | ||
| AU2009903644 | 2009-08-05 | ||
| AU2009903644A AU2009903644A0 (en) | 2009-08-05 | S1P Receptors Modulators and their use Thereof | |
| PCT/AU2009/001371 WO2010043000A1 (en) | 2008-10-17 | 2009-10-19 | S1p receptors modulators and their use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014192502A Division JP5963823B2 (ja) | 2008-10-17 | 2014-09-22 | S1p受容体モジュレーターおよびそれらの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012505836A JP2012505836A (ja) | 2012-03-08 |
| JP2012505836A5 true JP2012505836A5 (enExample) | 2013-02-07 |
Family
ID=42106136
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011531305A Pending JP2012505836A (ja) | 2008-10-17 | 2009-10-19 | S1p受容体モジュレーターおよびそれらの使用 |
| JP2014192502A Expired - Fee Related JP5963823B2 (ja) | 2008-10-17 | 2014-09-22 | S1p受容体モジュレーターおよびそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014192502A Expired - Fee Related JP5963823B2 (ja) | 2008-10-17 | 2014-09-22 | S1p受容体モジュレーターおよびそれらの使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US8592399B2 (enExample) |
| EP (1) | EP2344484B1 (enExample) |
| JP (2) | JP2012505836A (enExample) |
| CN (1) | CN102186845B (enExample) |
| AU (1) | AU2009304598B2 (enExample) |
| CA (1) | CA2740484C (enExample) |
| ES (1) | ES2590904T3 (enExample) |
| NZ (1) | NZ592748A (enExample) |
| WO (1) | WO2010043000A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102186845B (zh) | 2008-10-17 | 2016-09-07 | 阿卡制药有限公司 | S1p受体调节剂以及它们的用途 |
| CA2739901A1 (en) | 2008-10-17 | 2010-04-22 | Akaal Pharma Pty Ltd | S1p receptors modulators |
| AU2010213794A1 (en) * | 2009-02-10 | 2011-09-01 | Abbott Laboratories | Agonists and antagonists of the S1P5 receptor, and methods of uses thereof |
| KR101956129B1 (ko) * | 2010-11-30 | 2019-03-12 | 아데쏘 어드밴스드 머트리얼스 우후 컴퍼니 리미티드 | 신규한 재생 에폭시 수지용 물질 |
| EP2697195A1 (en) * | 2011-04-14 | 2014-02-19 | Allergan, Inc. | Phenyl bicyclic methyl azetidine derivatives as sphingosine-1 phosphate receptors modulators |
| CN102993027B (zh) * | 2011-09-08 | 2014-08-13 | 中化蓝天集团有限公司 | 4-氟-n-异丙基苯胺的定向单烷基化制备方法 |
| AU2012354695B2 (en) | 2011-12-23 | 2016-11-03 | Meiji Seika Pharma Co., Ltd. | Novel S1P receptor modulator |
| US9376409B2 (en) | 2012-05-09 | 2016-06-28 | Boehringer Ingelheim International Gmbh | Methods for making oxetan-3-ylmethanamines |
| BR112015001613B1 (pt) | 2012-07-27 | 2021-02-23 | Biogen Ma Inc | compostos que são agentes de modulação de s1p e/ou agentes de modulação de atx, seus usos e composição farmacêutica |
| US8859598B2 (en) | 2012-10-04 | 2014-10-14 | Allergan, Inc. | 1, 2, 4-oxadiazoles azetidine derivatives as sphingosine-1 phosphate receptors modulators |
| WO2014063199A1 (en) * | 2012-10-26 | 2014-05-01 | Akaal Pharma Pty Ltd | Organic compounds |
| EP2917214B1 (en) | 2012-11-07 | 2019-08-28 | Nerviano Medical Sciences S.r.l. | Substituted pyrimidinyl and pyridinyl-pyrrolopyridinones, process for their preparation and their use as kinase inhibitors |
| US8735433B1 (en) | 2012-11-14 | 2014-05-27 | Allergan, Inc. | Aryl oxadiazole derivatives as sphingosine 1-phosphate (S1P) receptor modulators |
| CN103304503B (zh) * | 2013-06-02 | 2015-03-04 | 张远强 | 抗糖尿病化合物、其制备方法和用途 |
| CN103304499B (zh) * | 2013-06-02 | 2015-03-04 | 张远强 | 抗糖尿病化合物、其制备方法和用途 |
| WO2015023839A1 (en) * | 2013-08-15 | 2015-02-19 | Allergan, Inc. | Aryl azetidine derivatives as sphingosine-1 phosphate receptors modulators |
| JPWO2015129859A1 (ja) * | 2014-02-28 | 2017-03-30 | キッセイ薬品工業株式会社 | 新規なアニリン誘導体、それを含有する医薬組成物およびそれらの用途 |
| US9745253B2 (en) | 2015-03-13 | 2017-08-29 | Forma Therapeutics, Inc. | Alpha-cinnamide compounds and compositions as HDAC8 inhibitors |
| US20180228778A1 (en) * | 2015-08-11 | 2018-08-16 | Akaal Pharma Pty Ltd | Compositions comprising s1p receptor modulators |
| AU2017218889A1 (en) | 2016-02-09 | 2018-08-30 | Pharmakea, Inc. | Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof |
| JP7273722B2 (ja) | 2016-12-20 | 2023-05-15 | オリゴメリックス インコーポレイテッド | タウオリゴマーの形成を阻害する新規ベンゾフラン、ベンゾチオフェン及びインドール類似体並びにそれらの使用方法 |
| JP7273723B2 (ja) | 2016-12-20 | 2023-05-15 | オリゴメリックス インコーポレイテッド | タウオリゴマーの形成を阻害する新規キナゾリノン及びその使用方法 |
| CN110831593A (zh) | 2017-06-14 | 2020-02-21 | 特维娜有限公司 | 用于调节s1p1活性的化合物及其使用方法 |
| KR102017324B1 (ko) * | 2018-04-30 | 2019-09-02 | 경북대학교 산학협력단 | 신규한 asm 활성 직접 억제 화합물 2-아미노-2-(1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체 및 이의 용도 |
| WO2020077014A1 (en) | 2018-10-09 | 2020-04-16 | Duke University | Compositions and methods for adjuvant cancer therapeutics |
| TWI838437B (zh) * | 2018-12-06 | 2024-04-11 | 大陸商上海濟煜醫藥科技有限公司 | 作為免疫調節劑的化合物及其製備方法和應用 |
| CN109824685B (zh) * | 2019-04-03 | 2021-03-23 | 辽宁中医药大学 | 马齿苋中化合物oleracone G及其提取分离方法与应用 |
| BR112022003959A2 (pt) * | 2019-09-05 | 2022-05-24 | Trevena Inc | Métodos para tratamento de epilepsia |
| MX2022005766A (es) | 2019-11-19 | 2022-08-08 | Trevena Inc | Compuestos y métodos para la preparación de compuestos moduladores de esfingosina 1-fosfato tipo 1 (s1p1). |
| AU2021228371A1 (en) * | 2020-02-28 | 2022-10-13 | Akaal Pharma Pty Ltd | S1P receptor modulators |
| JP2024510435A (ja) | 2021-03-18 | 2024-03-07 | シージェン インコーポレイテッド | 生体活性化合物の内部移行複合体からの選択的薬物放出 |
| TW202430514A (zh) | 2022-09-30 | 2024-08-01 | 瑞士商先正達農作物保護股份公司 | 殺微生物之吡唑衍生物 |
| TW202430031A (zh) | 2022-09-30 | 2024-08-01 | 瑞士商先正達農作物保護股份公司 | 殺微生物之吡唑衍生物 |
| JP2025539452A (ja) | 2022-11-30 | 2025-12-05 | シンジェンタ クロップ プロテクション アクチェンゲゼルシャフト | 殺微生物テトラヒドロイソキノリン誘導体 |
| WO2025114167A1 (en) | 2023-11-28 | 2025-06-05 | Syngenta Crop Protection Ag | Microbiocidal pyrazole derivatives |
| WO2025191053A1 (en) | 2024-03-14 | 2025-09-18 | Syngenta Crop Protection Ag | Microbiocidal pyrazole derivatives |
| WO2025210096A1 (en) | 2024-04-03 | 2025-10-09 | Syngenta Crop Protection Ag | Fungicidal compositions |
| WO2025210095A1 (en) | 2024-04-03 | 2025-10-09 | Syngenta Crop Protection Ag | Microbiocidal tetrahydroisoquinoline compounds |
| CN118878551B (zh) * | 2024-07-08 | 2026-04-28 | 安徽大学 | 一种4-溴噻吩并[2,3-c]吡啶-2-羧酸乙酯的制备方法 |
Family Cites Families (55)
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| US2550646A (en) | 1947-08-21 | 1951-04-24 | Commercial Solvents Corp | Polyamino alcohols and method for preparing them |
| DK0513387T3 (da) * | 1990-11-30 | 2000-06-05 | Otsuka Pharma Co Ltd | Thiazolderivater som inhibitorer af aktivt oxygen |
| AU674613B2 (en) * | 1993-09-28 | 1997-01-02 | Otsuka Pharmaceutical Co., Ltd. | Quinoxaline derivative as antidiabetic agent |
| FR2719044B1 (fr) * | 1994-04-26 | 1996-05-31 | Cird Galderma | Nouveaux composés bi-aromatiques acétylénés à groupement adamantyle, compositions pharmaceutiques et cosmétiques les contenant et utilisations. |
| US5883106A (en) * | 1994-10-18 | 1999-03-16 | Pfizer Inc. | 5-lipoxygenase inhibitors |
| JP3964478B2 (ja) | 1995-06-30 | 2007-08-22 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬 |
| US6221865B1 (en) | 1995-11-06 | 2001-04-24 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| FR2741876B1 (fr) * | 1995-12-01 | 1998-01-09 | Cird Galderma | Composes biaromatiques portant un groupement adamantyl en para, compositions pharmaceutiques et cosmetiques les contenant et utilisations |
| JPH10158192A (ja) | 1996-10-03 | 1998-06-16 | Eisai Co Ltd | 移植片対宿主疾患(gvhd)の治療および臓器移植時の移植片拒絶反応抑制のための医薬組成物 |
| US6228868B1 (en) | 1998-07-27 | 2001-05-08 | Abbott Laboratories | Oxazoline antiproliferative agents |
| WO2000037464A2 (en) * | 1998-12-18 | 2000-06-29 | Basilea Pharmaceutica Ag | 4-(aminoalkoxy)benzofurans as n-myristoyltransferase inhibitors |
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| JP4612990B2 (ja) * | 2001-03-16 | 2011-01-12 | アボット・ラボラトリーズ | ヒスタミン−3受容体リガンドとしての新規アミンおよびそれらの治療的適用 |
| US20040106794A1 (en) * | 2001-04-16 | 2004-06-03 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
| TW200304375A (en) | 2001-12-06 | 2003-10-01 | Maxia Pharmaceuticals Inc | 2-Substituted thiazolidinone and oxazolidinone derivatives for the inhibition of phosphatases and the treatment of cancer |
| US6951880B2 (en) * | 2002-05-16 | 2005-10-04 | Genelabs Technologies, Inc. | Aryl and heteroaryl compounds as antibacterial and antifungal agents |
| BR0317430A (pt) * | 2002-12-20 | 2005-10-25 | Pharmacia Corp | Compostos inibidores de quinase-2 de proteìna ativada por quinase de proteìna ativada por mitógeno |
| DK1602660T3 (da) * | 2003-02-18 | 2011-05-23 | Kyorin Seiyaku Kk | Aminophosphonsyrederivater, additionssalte deraf og S1P-receptormodulatorer |
| AU2004240649A1 (en) * | 2003-05-19 | 2004-12-02 | Irm, Llc | Immunosuppressant compounds and compositions |
| AU2004268455B2 (en) * | 2003-08-29 | 2009-12-17 | Ono Pharmaceutical Co., Ltd. | Compound capable of binding S1P receptor and pharmaceutical use thereof |
| WO2005032471A2 (en) | 2003-10-03 | 2005-04-14 | Merck & Co., Inc. | Benzylether and benzylamino beta-secretase inhibitors for the treatment of alzheimer's disease |
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| BRPI0512252A (pt) * | 2004-06-18 | 2008-02-19 | Biolipox Ab | composto ou um sal farmaceuticamente aceitável do mesmo, formulação farmacêutica, uso de um composto, método de tratamento de uma doença, produto combinado, e, processo para a preparação de um composto |
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| WO2006115188A1 (ja) | 2005-04-22 | 2006-11-02 | Daiichi Sankyo Company, Limited | ヘテロ環化合物 |
| FR2887882B1 (fr) * | 2005-07-01 | 2007-09-07 | Sanofi Aventis Sa | Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique |
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| WO2008099781A1 (ja) | 2007-02-13 | 2008-08-21 | Kyorin Pharmaceutical Co., Ltd. | アミノアルコール誘導体を有効成分とする脱髄性疾患の治療剤又は予防剤 |
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| US20090118349A1 (en) | 2007-08-16 | 2009-05-07 | Onco-Pharmakon Incorporated | Bis-alkylating agents and their use in cancer therapy |
| EP2297139A1 (en) * | 2008-06-20 | 2011-03-23 | Glaxo Group Limited | Compounds |
| CN102186845B (zh) | 2008-10-17 | 2016-09-07 | 阿卡制药有限公司 | S1p受体调节剂以及它们的用途 |
| CA2739901A1 (en) | 2008-10-17 | 2010-04-22 | Akaal Pharma Pty Ltd | S1p receptors modulators |
| US20100160369A1 (en) | 2008-12-04 | 2010-06-24 | Exelixis, Inc. | S1P1 Agonists and Methods of Making And Using |
| US8741923B2 (en) | 2008-12-18 | 2014-06-03 | Merck Serono Sa | Oxadiazole fused heterocyclic derivatives useful for the treatment of multiple sclerosis |
| WO2014063199A1 (en) * | 2012-10-26 | 2014-05-01 | Akaal Pharma Pty Ltd | Organic compounds |
-
2009
- 2009-10-19 CN CN200980141188.9A patent/CN102186845B/zh active Active
- 2009-10-19 CA CA2740484A patent/CA2740484C/en active Active
- 2009-10-19 NZ NZ592748A patent/NZ592748A/xx unknown
- 2009-10-19 WO PCT/AU2009/001371 patent/WO2010043000A1/en not_active Ceased
- 2009-10-19 US US13/124,549 patent/US8592399B2/en active Active
- 2009-10-19 AU AU2009304598A patent/AU2009304598B2/en not_active Ceased
- 2009-10-19 ES ES09820119.7T patent/ES2590904T3/es active Active
- 2009-10-19 JP JP2011531305A patent/JP2012505836A/ja active Pending
- 2009-10-19 EP EP09820119.7A patent/EP2344484B1/en active Active
-
2013
- 2013-10-29 US US14/066,276 patent/US9193716B2/en active Active
-
2014
- 2014-09-22 JP JP2014192502A patent/JP5963823B2/ja not_active Expired - Fee Related
-
2015
- 2015-10-22 US US14/920,780 patent/US9707205B2/en active Active
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