JP2008514732A5 - - Google Patents

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Publication number
JP2008514732A5
JP2008514732A5 JP2007534872A JP2007534872A JP2008514732A5 JP 2008514732 A5 JP2008514732 A5 JP 2008514732A5 JP 2007534872 A JP2007534872 A JP 2007534872A JP 2007534872 A JP2007534872 A JP 2007534872A JP 2008514732 A5 JP2008514732 A5 JP 2008514732A5
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JP
Japan
Prior art keywords
carbon atoms
cyclosporine
different
same
group
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JP2007534872A
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English (en)
Japanese (ja)
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JP5139065B2 (ja
JP2008514732A (ja
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Priority claimed from PCT/US2005/035533 external-priority patent/WO2006039668A2/en
Publication of JP2008514732A publication Critical patent/JP2008514732A/ja
Publication of JP2008514732A5 publication Critical patent/JP2008514732A5/ja
Application granted granted Critical
Publication of JP5139065B2 publication Critical patent/JP5139065B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2007534872A 2004-10-01 2005-09-30 Ｃ型肝炎感染の治療及び予防のための３−エーテル及び３−チオエーテル置換シクロスポリン誘導体 Expired - Fee Related JP5139065B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US61515204P 2004-10-01 2004-10-01
US60/615,152 2004-10-01
US70762605P 2005-08-11 2005-08-11
US60/707,626 2005-08-11
PCT/US2005/035533 WO2006039668A2 (en) 2004-10-01 2005-09-30 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis c infection

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012106395A Division JP2012167113A (ja) 2004-10-01 2012-05-08 Ｃ型肝炎感染の治療及び予防のための３−エーテル及び３−チオエーテル置換シクロスポリン誘導体

Publications (3)

Publication Number Publication Date
JP2008514732A JP2008514732A (ja) 2008-05-08
JP2008514732A5 true JP2008514732A5 (enExample) 2008-11-13
JP5139065B2 JP5139065B2 (ja) 2013-02-06

Family

ID=36143148

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007534872A Expired - Fee Related JP5139065B2 (ja) 2004-10-01 2005-09-30 Ｃ型肝炎感染の治療及び予防のための３−エーテル及び３−チオエーテル置換シクロスポリン誘導体
JP2012106395A Pending JP2012167113A (ja) 2004-10-01 2012-05-08 Ｃ型肝炎感染の治療及び予防のための３−エーテル及び３−チオエーテル置換シクロスポリン誘導体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012106395A Pending JP2012167113A (ja) 2004-10-01 2012-05-08 Ｃ型肝炎感染の治療及び予防のための３−エーテル及び３−チオエーテル置換シクロスポリン誘導体

Country Status (19)

Country Link
US (2) US20100167996A1 (enExample)
EP (1) EP1802650B1 (enExample)
JP (2) JP5139065B2 (enExample)
KR (1) KR101309409B1 (enExample)
CN (1) CN101773661B (enExample)
AT (1) ATE530561T1 (enExample)
AU (1) AU2005292162B2 (enExample)
BR (1) BRPI0516737A (enExample)
CA (1) CA2583494C (enExample)
DK (1) DK1802650T3 (enExample)
ES (1) ES2373450T3 (enExample)
IL (1) IL182315A (enExample)
MX (1) MX2007003538A (enExample)
NZ (1) NZ554514A (enExample)
PL (1) PL1802650T3 (enExample)
PT (1) PT1802650E (enExample)
RU (1) RU2399628C2 (enExample)
SI (1) SI1802650T1 (enExample)
WO (1) WO2006039668A2 (enExample)

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KR101273681B1 (ko) 2005-10-26 2013-06-25 아스텔라스세이야쿠 가부시키가이샤 신규 시클릭 펩티드 화합물
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US8536114B2 (en) 2008-12-31 2013-09-17 Scynexis, Inc. Macrocycles
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US20110182850A1 (en) 2009-04-10 2011-07-28 Trixi Brandl Organic compounds and their uses
US8349312B2 (en) 2009-07-09 2013-01-08 Enanta Pharmaceuticals, Inc. Proline substituted cyclosporin analogues
US8685917B2 (en) 2009-07-09 2014-04-01 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
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KR20120106942A (ko) 2009-10-30 2012-09-27 베링거 인겔하임 인터내셔날 게엠베하 Ｂｉ２０１３３５, 인터페론 알파 및 리바비린을 포함하는 ｈｃｖ 병용 치료요법을 위한 투여 용법
CN102869367A (zh) 2009-12-09 2013-01-09 西尼克斯公司 新颖的环肽
MX2012007076A (es) * 2009-12-18 2012-07-20 Boehringer Ingelheim Int Terapia combinada de hcv.
CA2785978A1 (en) 2009-12-30 2011-07-07 Scynexis, Inc. Cyclosporine analogues
US8623814B2 (en) 2010-02-23 2014-01-07 Enanta Pharmaceuticals, Inc. Antiviral agents
US9217015B2 (en) 2010-07-16 2015-12-22 S&T Global Inc. Cyclosporin derivatives for the treatment and prevention of a viral infection
CN103153330B (zh) 2010-08-12 2017-08-18 美国科技环球有限公司 新的环孢霉素衍生物在病毒感染的治疗和预防中的应用
CN103179966B (zh) 2010-10-08 2017-03-15 诺瓦提斯公司 磺酰胺ns3抑制剂的维生素e制剂
MX350746B (es) * 2010-12-03 2017-09-14 Hebei Kunxiangjishi Pharmaceutical Tech Co Ltd Derivados de ciclosporina novedosos para el tratamiento y la prevención de una infección viral.
US9890198B2 (en) 2010-12-03 2018-02-13 S&T Global Inc. Cyclosporin derivatives and uses thereof
AU2011342284C1 (en) 2010-12-15 2017-07-13 Contravir Pharmaceuticals, Inc. Cyclosporine analogue molecules modified at amino acid 1 and 3
RU2448690C1 (ru) * 2011-03-15 2012-04-27 Открытое акционерное общество "Биосинтез" Твердая лекарственная форма пролонгированного действия нестероидного противовоспалительного средства кетопрофен, способ получения
CN103987399A (zh) * 2011-08-19 2014-08-13 美国科技环球有限公司 用于治疗和预防病毒感染的新型环孢菌素衍生物
WO2013181339A2 (en) 2012-06-01 2013-12-05 Allergan, Inc. Cyclosporin a analogs
US8906853B2 (en) 2012-11-28 2014-12-09 Enanta Pharmaceuticals, Inc. [N-Me-4-hydroxyleucine]-9-cyclosporin analogues for treatment and prevention of hepatitis C infection
US20140205566A1 (en) 2012-11-30 2014-07-24 Novartis Ag Cyclic nucleuoside derivatives and uses thereof
HK1223843A1 (zh) * 2013-08-26 2017-08-11 Enanta Pharmaceuticals, Inc. 用於預防或治療丙型肝炎的環孢菌素類似物
US9669095B2 (en) 2014-11-03 2017-06-06 Enanta Pharmaceuticals, Inc. Cyclosporin analogues for preventing or treating hepatitis C infection
TW201639873A (zh) 2015-01-08 2016-11-16 歐樂根公司 Ｍｅｂｍｔ側鏈已環化之環孢菌素衍生物
EP3277704A1 (en) 2015-03-31 2018-02-07 Allergan, Inc. Cyclosporins modified on the mebmt sidechain by heterocyclic rings
CN108025039B (zh) * 2015-06-30 2022-07-29 西普拉里斯有限公司 新颖的大环化合物
GB201711749D0 (en) * 2017-07-21 2017-09-06 Cypralis Ltd Cyclosporin analogues and uses thereof
WO2020037530A1 (en) 2018-08-22 2020-02-27 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Crystalline form of compound and uses thereof in medicine
CN116870135A (zh) 2019-10-12 2023-10-13 睿诺医疗科技（上海）有限公司 肾毒素诱发的肾损伤的治疗和预防
CA3172535A1 (en) * 2020-03-26 2021-09-30 Ching-Pong Mak Cyclophilin inhibitors and uses thereof
AU2021256222A1 (en) * 2020-04-15 2022-10-06 Farsight Medical Technology (Shanghai) Co., Ltd. Prevention and treatment of organ injuries
WO2026119137A1 (en) * 2024-12-03 2026-06-11 Farsight Medical Technology (Shanghai) Co., Ltd. Cyclosporin analogues and uses in hepatitis b therapies

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WO2007041632A2 (en) * 2005-09-30 2007-04-12 Scynexis, Inc. Methods and pharmaceutical compositions for the treatment and prevention of hepatitis c infection
CA2652662C (en) * 2006-05-19 2015-11-03 Scynexis, Inc. Methods for the treatment and prevention of ocular disorders
WO2008069917A2 (en) * 2006-11-20 2008-06-12 Scynexis, Inc. Novel cyclic peptides
WO2008127613A1 (en) * 2007-04-11 2008-10-23 Scynexis, Inc. New pharmaceutical compositions
JP5820722B2 (ja) * 2008-06-06 2015-11-24 スシネキス インク シクロスポリン類似体及びｈｃｖ感染の治療におけるその使用
US20090306033A1 (en) * 2008-06-06 2009-12-10 Keqiang Li Novel cyclic peptides
US8536114B2 (en) * 2008-12-31 2013-09-17 Scynexis, Inc. Macrocycles
CN102271688A (zh) * 2009-01-07 2011-12-07 西尼克斯公司 用于治疗hcv的环孢菌素衍生物和核苷的组合
KR20110116136A (ko) * 2009-01-07 2011-10-25 싸이넥시스, 인크. Ｈｃｖ 및 ｈｉｖ 감염의 치료에 사용하기 위한 사이클로스포린 유도체
CN102869367A (zh) * 2009-12-09 2013-01-09 西尼克斯公司 新颖的环肽

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