JP2010509356A5 - - Google Patents

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Publication number
JP2010509356A5
JP2010509356A5 JP2009536454A JP2009536454A JP2010509356A5 JP 2010509356 A5 JP2010509356 A5 JP 2010509356A5 JP 2009536454 A JP2009536454 A JP 2009536454A JP 2009536454 A JP2009536454 A JP 2009536454A JP 2010509356 A5 JP2010509356 A5 JP 2010509356A5
Authority
JP
Japan
Prior art keywords
pyrrolo
pyridin
substituted
phenyl
benzamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009536454A
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English (en)
Japanese (ja)
Other versions
JP2010509356A (ja
JP5244118B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/083850 external-priority patent/WO2008060907A2/en
Publication of JP2010509356A publication Critical patent/JP2010509356A/ja
Publication of JP2010509356A5 publication Critical patent/JP2010509356A5/ja
Application granted granted Critical
Publication of JP5244118B2 publication Critical patent/JP5244118B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009536454A 2006-11-10 2007-11-07 新規キナーゼ阻害剤 Expired - Fee Related JP5244118B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86518106P 2006-11-10 2006-11-10
US60/865,181 2006-11-10
PCT/US2007/083850 WO2008060907A2 (en) 2006-11-10 2007-11-07 Pyrrolo-pyridine kinase inhibitors

Publications (3)

Publication Number Publication Date
JP2010509356A JP2010509356A (ja) 2010-03-25
JP2010509356A5 true JP2010509356A5 (enExample) 2010-10-21
JP5244118B2 JP5244118B2 (ja) 2013-07-24

Family

ID=39261598

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009536454A Expired - Fee Related JP5244118B2 (ja) 2006-11-10 2007-11-07 新規キナーゼ阻害剤

Country Status (6)

Country Link
US (1) US8148361B2 (enExample)
EP (1) EP2081928B1 (enExample)
JP (1) JP5244118B2 (enExample)
CN (1) CN101600714B (enExample)
NO (1) NO20091708L (enExample)
WO (1) WO2008060907A2 (enExample)

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US9388185B2 (en) 2012-08-10 2016-07-12 Incyte Holdings Corporation Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
WO2014048878A1 (en) * 2012-09-26 2014-04-03 Evotec (Uk) Ltd. Phenyl- or pyridyl- pyrrolo[2,3b]pyrazine derivatives useful in the treatment or prevention of proliferative disorders or dysplasia
US8999632B2 (en) 2012-10-04 2015-04-07 Vertex Pharmaceuticals Incorporated Method for measuring ATR inhibition mediated increases in DNA damage
EP2909202A1 (en) 2012-10-16 2015-08-26 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of atr kinase
US9340546B2 (en) 2012-12-07 2016-05-17 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
US9266892B2 (en) 2012-12-19 2016-02-23 Incyte Holdings Corporation Fused pyrazoles as FGFR inhibitors
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US9663519B2 (en) 2013-03-15 2017-05-30 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
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WO2015085132A1 (en) 2013-12-06 2015-06-11 Vertex Pharmaceuticals Incorporated 2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]pyrazolo[1,5-a]pyrimidin-3-carboxamide compound useful as atr kinase inhibitor, its preparation, different solid forms and radiolabelled derivatives thereof
BR112016022062B1 (pt) 2014-03-26 2023-04-11 Astex Therapeutics Limited Combinação, composição farmacêutica, uso de uma combinação ou de uma composição farmacêutica, e, produto farmacêutico
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CN107074863B (zh) 2014-06-05 2019-12-03 沃泰克斯药物股份有限公司 Atr激酶抑制剂的制备方法及其不同的固体形式
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US10851105B2 (en) 2014-10-22 2020-12-01 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
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MX373169B (es) 2015-02-20 2020-04-24 Incyte Holdings Corp Heterociclos bicíclicos como inhibidores de receptores del factor de crecimiento fibroblástico (fgfr).
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CR20240498A (es) 2018-05-04 2025-01-08 Incyte Corp FORMAS SÓLIDAS DE UN INHIBIDOR DE FGFR Y PROCESOS PARA PREPARARLAS (Divisional EXP. 2020-0590)
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