JP2010504351A5 - - Google Patents
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- Publication number
- JP2010504351A5 JP2010504351A5 JP2009529369A JP2009529369A JP2010504351A5 JP 2010504351 A5 JP2010504351 A5 JP 2010504351A5 JP 2009529369 A JP2009529369 A JP 2009529369A JP 2009529369 A JP2009529369 A JP 2009529369A JP 2010504351 A5 JP2010504351 A5 JP 2010504351A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- benzazepine
- carbonyl
- spiro
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CC=C(C1OC1*(CCC1(**CC1)C1)c2c1cc(C)cc2)C=C(C(*C(c1c(*)ccc(O)c1)=O)=I)S* Chemical compound CC=C(C1OC1*(CCC1(**CC1)C1)c2c1cc(C)cc2)C=C(C(*C(c1c(*)ccc(O)c1)=O)=I)S* 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82665406P | 2006-09-22 | 2006-09-22 | |
| PCT/US2007/078917 WO2008036755A1 (en) | 2006-09-22 | 2007-09-19 | Spiro benzazepines used as vasopressin antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010504351A JP2010504351A (ja) | 2010-02-12 |
| JP2010504351A5 true JP2010504351A5 (enExample) | 2010-12-02 |
Family
ID=39030853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009529369A Pending JP2010504351A (ja) | 2006-09-22 | 2007-09-19 | バソプレッシン拮抗薬として使用されるスピロベンズアゼピン類 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7825110B2 (enExample) |
| EP (1) | EP2078022B1 (enExample) |
| JP (1) | JP2010504351A (enExample) |
| CN (1) | CN101541806A (enExample) |
| AT (1) | ATE532786T1 (enExample) |
| AU (1) | AU2007299818B2 (enExample) |
| CA (1) | CA2665849A1 (enExample) |
| CY (1) | CY1112270T1 (enExample) |
| DK (1) | DK2078022T3 (enExample) |
| ES (1) | ES2374582T3 (enExample) |
| PL (1) | PL2078022T3 (enExample) |
| PT (1) | PT2078022E (enExample) |
| SI (1) | SI2078022T1 (enExample) |
| WO (1) | WO2008036755A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013057944A1 (ja) * | 2011-10-19 | 2013-04-25 | 興和株式会社 | 新規なスピロインドリン化合物、及びそれを含有する医薬 |
| US10214520B2 (en) | 2014-07-15 | 2019-02-26 | Gruenenthal Gmbh | Substituted azaspiro(4.5)decane derivatives |
| TW201607923A (zh) | 2014-07-15 | 2016-03-01 | 歌林達有限公司 | 被取代之氮螺環(4.5)癸烷衍生物 |
| EP3321271B1 (en) | 2015-07-07 | 2024-05-29 | Japan Tobacco Inc. | Method for producing 7h-pyrrolo[2, 3-d]pyrimidine derivative and intermediate thereof |
| MX2019007542A (es) * | 2016-12-21 | 2019-11-18 | Japan Tobacco Inc | Proceso para la preparación de derivados de 7h-pirrolo [2, 3-d] pirimidina y sus intermedios sintéticos. |
| IL273228B2 (en) * | 2017-09-15 | 2025-04-01 | Azevan Pharmaceuticals Inc | Preparations and methods for treating brain injury |
| US20200337590A1 (en) | 2018-01-16 | 2020-10-29 | Bayer Aktiengesellschaft | Assistance in the treatment of cardiac insufficiency |
| TW202220958A (zh) * | 2020-08-07 | 2022-06-01 | 美商卡司馬療法公司 | Trpml調節劑 |
| JP7627343B2 (ja) * | 2020-11-26 | 2025-02-05 | シャンハイ ジェミンケア ファーマシューティカル カンパニー,リミティド | 新規ベンズアゼピンスピロ環式誘導体 |
| CN112939864B (zh) * | 2021-01-29 | 2022-05-06 | 中国医科大学 | 螺[苯并[c]氮杂-1,1’-环己基]-3-酮类化合物 |
| EP4491699A1 (de) | 2023-07-13 | 2025-01-15 | Klueber Lubrication München GmbH & Co. KG | Phthalimidverbindungen als basisöl für schmierstoffzusammensetzungen |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4617302A (en) * | 1984-10-15 | 1986-10-14 | Eli Lilly And Company | Inotropic agents |
| WO1991005549A1 (en) * | 1989-10-20 | 1991-05-02 | Otsuka Pharmaceutical Co., Ltd. | Benzoheterocyclic compounds |
| US5258510A (en) * | 1989-10-20 | 1993-11-02 | Otsuka Pharma Co Ltd | Benzoheterocyclic compounds |
| JP2905909B2 (ja) * | 1991-04-19 | 1999-06-14 | 大塚製薬株式会社 | バソプレシン拮抗剤 |
| US5985869A (en) * | 1989-10-20 | 1999-11-16 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds |
| FR2686878B1 (fr) * | 1992-01-30 | 1995-06-30 | Sanofi Elf | Derives du n-sulfonyl oxo-2 indole, leur preparation, les compositions pharmaceutiques en contenant. |
| US5686624A (en) * | 1992-01-30 | 1997-11-11 | Sanofi | 1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present |
| US5663431A (en) * | 1992-01-30 | 1997-09-02 | Sanofi | 1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present |
| FR2708605A1 (fr) | 1993-07-30 | 1995-02-10 | Sanofi Sa | Dérivés du N-sulfonylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant. |
| US5849780A (en) * | 1992-01-30 | 1998-12-15 | Sanofi | 1-benzenesulfonyl-1-1,3-dihydroindol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present |
| CA2143117A1 (en) | 1992-10-07 | 1994-04-14 | Ben E. Evans | Tocolytic oxytocin receptor antagonists |
| US5512563A (en) | 1993-07-29 | 1996-04-30 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
| FR2708606B1 (fr) * | 1993-07-30 | 1995-10-27 | Sanofi Sa | Dérivés du N-phénylalkylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant. |
| US5464788A (en) | 1994-03-24 | 1995-11-07 | Merck & Co., Inc. | Tocolytic oxytocin receptor antagonists |
| US5753648A (en) | 1995-01-17 | 1998-05-19 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
| AUPP150098A0 (en) | 1998-01-27 | 1998-02-19 | Fujisawa Pharmaceutical Co., Ltd. | Benzamide derivatives |
| JP4916639B2 (ja) | 2000-07-05 | 2012-04-18 | オーソーマクニール ファーマシューティカル, インコーポレイテッド | バソプレシン拮抗質としての非ペプチド系置換スピロベンゾアゼピン |
| CA2432825A1 (en) * | 2000-12-15 | 2002-06-20 | Emory University | Nonpeptide agonists and antagonists of vasopressin receptors |
| US7011898B2 (en) * | 2003-03-21 | 2006-03-14 | Air Products And Chemicals, Inc. | Method of joining ITM materials using a partially or fully-transient liquid phase |
| DK1633719T3 (da) | 2003-06-17 | 2010-01-04 | Janssen Pharmaceutica Nv | Substituerede spirobenzazepiner |
| HRP20051005A2 (en) | 2003-06-17 | 2006-09-30 | Janssen Pharmaceutica N.V. | Process for the preparation of nonpeptide substituted spirobenzoazepine derivatives |
| CA2637838A1 (en) | 2006-01-20 | 2007-07-26 | Janssen Pharmaceutica N.V. | Novel solid forms of (4r)-1-¬4-(2-chloro-5-fluorobenzoyl)amino-3-methoxybenzoyl|-1,2,3,5-tetrahydro-spiro¬4h-1-benzazepine-4,1'-¬2|cyclopentene|-3'-carboxylic acid |
-
2007
- 2007-09-19 SI SI200730800T patent/SI2078022T1/sl unknown
- 2007-09-19 PT PT07842799T patent/PT2078022E/pt unknown
- 2007-09-19 ES ES07842799T patent/ES2374582T3/es active Active
- 2007-09-19 WO PCT/US2007/078917 patent/WO2008036755A1/en not_active Ceased
- 2007-09-19 CN CNA2007800432003A patent/CN101541806A/zh active Pending
- 2007-09-19 JP JP2009529369A patent/JP2010504351A/ja active Pending
- 2007-09-19 EP EP07842799A patent/EP2078022B1/en active Active
- 2007-09-19 AU AU2007299818A patent/AU2007299818B2/en not_active Expired - Fee Related
- 2007-09-19 DK DK07842799.4T patent/DK2078022T3/da active
- 2007-09-19 CA CA002665849A patent/CA2665849A1/en not_active Abandoned
- 2007-09-19 US US11/857,891 patent/US7825110B2/en not_active Expired - Fee Related
- 2007-09-19 PL PL07842799T patent/PL2078022T3/pl unknown
- 2007-09-19 AT AT07842799T patent/ATE532786T1/de active
-
2012
- 2012-01-24 CY CY20121100081T patent/CY1112270T1/el unknown
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