PL2078022T3 - Spirobenzoazepiny stosowane jako antagoniści wazopresyny - Google Patents
Spirobenzoazepiny stosowane jako antagoniści wazopresynyInfo
- Publication number
- PL2078022T3 PL2078022T3 PL07842799T PL07842799T PL2078022T3 PL 2078022 T3 PL2078022 T3 PL 2078022T3 PL 07842799 T PL07842799 T PL 07842799T PL 07842799 T PL07842799 T PL 07842799T PL 2078022 T3 PL2078022 T3 PL 2078022T3
- Authority
- PL
- Poland
- Prior art keywords
- renal
- hyponatremia
- hypertension
- insufficiency
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82665406P | 2006-09-22 | 2006-09-22 | |
EP07842799A EP2078022B1 (en) | 2006-09-22 | 2007-09-19 | Spiro benzazepines used as vasopressin antagonists |
PCT/US2007/078917 WO2008036755A1 (en) | 2006-09-22 | 2007-09-19 | Spiro benzazepines used as vasopressin antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2078022T3 true PL2078022T3 (pl) | 2012-04-30 |
Family
ID=39030853
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL07842799T PL2078022T3 (pl) | 2006-09-22 | 2007-09-19 | Spirobenzoazepiny stosowane jako antagoniści wazopresyny |
Country Status (14)
Country | Link |
---|---|
US (1) | US7825110B2 (pl) |
EP (1) | EP2078022B1 (pl) |
JP (1) | JP2010504351A (pl) |
CN (1) | CN101541806A (pl) |
AT (1) | ATE532786T1 (pl) |
AU (1) | AU2007299818B2 (pl) |
CA (1) | CA2665849A1 (pl) |
CY (1) | CY1112270T1 (pl) |
DK (1) | DK2078022T3 (pl) |
ES (1) | ES2374582T3 (pl) |
PL (1) | PL2078022T3 (pl) |
PT (1) | PT2078022E (pl) |
SI (1) | SI2078022T1 (pl) |
WO (1) | WO2008036755A1 (pl) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2781521A4 (en) | 2011-10-19 | 2015-03-04 | Kowa Co | NOVEL COMPOUND OF SPIROINDOLINE AND THERAPEUTIC AGENT CONTAINING THE SAME |
CA2955071A1 (en) | 2014-07-15 | 2016-01-21 | Grunenthal Gmbh | Substituted azaspiro(4.5)decane derivatives |
TW201607923A (zh) | 2014-07-15 | 2016-03-01 | 歌林達有限公司 | 被取代之氮螺環(4.5)癸烷衍生物 |
RU2755618C2 (ru) | 2015-07-07 | 2021-09-17 | Джапан Тобакко Инк. | Способ получения производного 7н-пирроло[2,3-d] пиримидина и его интермедиата |
CA3047891A1 (en) * | 2016-12-21 | 2018-06-28 | Japan Tobacco Inc. | Process for preparing 7h-pyrrolo[2,3-d]pyrimidine derivatives and synthetic intermediates thereof |
TW201919625A (zh) | 2017-09-15 | 2019-06-01 | 美商愛治凡製藥公司 | 用於治療腦損傷之組合物及方法 |
US20200337590A1 (en) | 2018-01-16 | 2020-10-29 | Bayer Aktiengesellschaft | Assistance in the treatment of cardiac insufficiency |
US20230416262A1 (en) * | 2020-08-07 | 2023-12-28 | Casma Therapeutics, Inc. | Trpml modulators |
WO2022111581A1 (zh) * | 2020-11-26 | 2022-06-02 | 上海济煜医药科技有限公司 | 新型苯并氮杂卓螺环衍生物 |
CN112939864B (zh) * | 2021-01-29 | 2022-05-06 | 中国医科大学 | 螺[苯并[c]氮杂-1,1’-环己基]-3-酮类化合物 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4617302A (en) | 1984-10-15 | 1986-10-14 | Eli Lilly And Company | Inotropic agents |
US5985869A (en) | 1989-10-20 | 1999-11-16 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds |
JP2905909B2 (ja) * | 1991-04-19 | 1999-06-14 | 大塚製薬株式会社 | バソプレシン拮抗剤 |
US5258510A (en) | 1989-10-20 | 1993-11-02 | Otsuka Pharma Co Ltd | Benzoheterocyclic compounds |
EP0450097B1 (en) | 1989-10-20 | 1996-04-24 | Otsuka Pharmaceutical Co., Ltd. | Benzoheterocyclic compounds |
US5663431A (en) | 1992-01-30 | 1997-09-02 | Sanofi | 1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present |
US5849780A (en) | 1992-01-30 | 1998-12-15 | Sanofi | 1-benzenesulfonyl-1-1,3-dihydroindol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present |
US5686624A (en) | 1992-01-30 | 1997-11-11 | Sanofi | 1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present |
FR2708605A1 (fr) * | 1993-07-30 | 1995-02-10 | Sanofi Sa | Dérivés du N-sulfonylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant. |
FR2686878B1 (fr) * | 1992-01-30 | 1995-06-30 | Sanofi Elf | Derives du n-sulfonyl oxo-2 indole, leur preparation, les compositions pharmaceutiques en contenant. |
AU5292393A (en) | 1992-10-07 | 1994-04-26 | Merck & Co., Inc. | Tocolytic oxytocin receptor antagonists |
US5512563A (en) | 1993-07-29 | 1996-04-30 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
FR2708606B1 (fr) * | 1993-07-30 | 1995-10-27 | Sanofi Sa | Dérivés du N-phénylalkylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant. |
US5464788A (en) | 1994-03-24 | 1995-11-07 | Merck & Co., Inc. | Tocolytic oxytocin receptor antagonists |
US5753648A (en) | 1995-01-17 | 1998-05-19 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
AUPP150098A0 (en) | 1998-01-27 | 1998-02-19 | Fujisawa Pharmaceutical Co., Ltd. | Benzamide derivatives |
MXPA03000135A (es) | 2000-07-05 | 2005-02-17 | Johnson & Johnson | Espirobenzoazepinas sustitudas no peptidicas como antagonistas de vasopresina. |
CA2432825A1 (en) * | 2000-12-15 | 2002-06-20 | Emory University | Nonpeptide agonists and antagonists of vasopressin receptors |
US7011898B2 (en) * | 2003-03-21 | 2006-03-14 | Air Products And Chemicals, Inc. | Method of joining ITM materials using a partially or fully-transient liquid phase |
CN1835926A (zh) * | 2003-06-17 | 2006-09-20 | 詹森药业有限公司 | 非肽类取代螺苯并氮杂䓬衍生物的制备方法 |
EA011089B1 (ru) * | 2003-06-17 | 2008-12-30 | Янссен Фармацевтика Н.В. | Замещённые спиробензазепины |
CA2637838A1 (en) * | 2006-01-20 | 2007-07-26 | Janssen Pharmaceutica N.V. | Novel solid forms of (4r)-1-¬4-(2-chloro-5-fluorobenzoyl)amino-3-methoxybenzoyl|-1,2,3,5-tetrahydro-spiro¬4h-1-benzazepine-4,1'-¬2|cyclopentene|-3'-carboxylic acid |
-
2007
- 2007-09-19 EP EP07842799A patent/EP2078022B1/en active Active
- 2007-09-19 US US11/857,891 patent/US7825110B2/en not_active Expired - Fee Related
- 2007-09-19 JP JP2009529369A patent/JP2010504351A/ja active Pending
- 2007-09-19 DK DK07842799.4T patent/DK2078022T3/da active
- 2007-09-19 AU AU2007299818A patent/AU2007299818B2/en not_active Expired - Fee Related
- 2007-09-19 AT AT07842799T patent/ATE532786T1/de active
- 2007-09-19 ES ES07842799T patent/ES2374582T3/es active Active
- 2007-09-19 PL PL07842799T patent/PL2078022T3/pl unknown
- 2007-09-19 PT PT07842799T patent/PT2078022E/pt unknown
- 2007-09-19 SI SI200730800T patent/SI2078022T1/sl unknown
- 2007-09-19 WO PCT/US2007/078917 patent/WO2008036755A1/en active Application Filing
- 2007-09-19 CN CNA2007800432003A patent/CN101541806A/zh active Pending
- 2007-09-19 CA CA002665849A patent/CA2665849A1/en not_active Abandoned
-
2012
- 2012-01-24 CY CY20121100081T patent/CY1112270T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
US20080076753A1 (en) | 2008-03-27 |
WO2008036755A1 (en) | 2008-03-27 |
US7825110B2 (en) | 2010-11-02 |
SI2078022T1 (sl) | 2012-01-31 |
EP2078022A1 (en) | 2009-07-15 |
AU2007299818A1 (en) | 2008-03-27 |
CN101541806A (zh) | 2009-09-23 |
ES2374582T3 (es) | 2012-02-20 |
AU2007299818B2 (en) | 2012-08-02 |
ATE532786T1 (de) | 2011-11-15 |
CA2665849A1 (en) | 2008-03-27 |
CY1112270T1 (el) | 2015-12-09 |
EP2078022B1 (en) | 2011-11-09 |
JP2010504351A (ja) | 2010-02-12 |
PT2078022E (pt) | 2012-01-11 |
DK2078022T3 (da) | 2012-02-13 |
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