|
DK3725807T3
(da)
|
2012-12-03 |
2026-01-12 |
Novimmune Sa |
Anti-cd47 antistoffer og fremgangsmåder til anvendelse deraf
|
|
CN106661570B
(zh)
|
2014-04-10 |
2020-02-07 |
西雅图儿童医院（Dba西雅图儿童研究所） |
通过与氨甲蝶呤选择偶联的睡美人转座子制备工程化t细胞
|
|
BR112016024579A2
(pt)
|
2014-04-23 |
2017-10-10 |
Juno Therapeutics Inc |
métodos para isolamento, cultura e engenharia genética de populações de célula imune para terapia adotiva
|
|
AU2015259877B2
(en)
|
2014-05-15 |
2021-02-25 |
National University Of Singapore |
Modified natural killer cells and uses thereof
|
|
KR101628872B1
(ko)
|
2014-05-28 |
2016-06-09 |
주식회사 레고켐 바이오사이언스 |
자가-희생 기를 포함하는 화합물
|
|
TWI805109B
(zh)
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
|
US10507219B2
(en)
|
2014-10-20 |
2019-12-17 |
Juno Therapeutics, Inc. |
Methods and compositions for dosing in adoptive cell therapy
|
|
US10493139B2
(en)
|
2015-07-24 |
2019-12-03 |
Innovative Cellular Therapeutics CO., LTD. |
Humanized anti-CD19 antibody and use thereof with chimeric antigen receptor
|
|
EP3331920A4
(en)
|
2015-08-07 |
2019-04-03 |
Seattle Children's Hospital, dba Seattle Children's Research Institute |
BIS SPECIFIC CAR T CELLS FOR TARGETING OF SOLID TUMORS
|
|
AU2016359234B2
(en)
|
2015-11-25 |
2022-09-08 |
Ligachem Biosciences Inc. |
Conjugates comprising peptide groups and methods related thereto
|
|
CN117244076A
(zh)
|
2015-11-25 |
2023-12-19 |
乐高化学生物科学股份有限公司 |
包含自降解基团的缀合物及其相关方法
|
|
EP3380126A4
(en)
|
2015-11-25 |
2019-07-24 |
LegoChem Biosciences, Inc. |
ANTIBODY-ACTIVE CONJUGATES WITH BRANCHED LINKERS AND ASSOCIATED METHODS
|
|
SG10202012157QA
(en)
|
2016-06-07 |
2021-01-28 |
Max Delbrueck Centrum Fuer Molekulare Medizin Helmholtz Gemeinschaft |
Chimeric antigen receptor and car-t cells that bind bcma
|
|
CN107793479B
(zh)
*
|
2016-09-06 |
2024-02-06 |
上海吉倍生物技术有限公司 |
一种抗cd19抗体及其制备方法和用途
|
|
WO2018083535A1
(en)
*
|
2016-11-04 |
2018-05-11 |
Novimmune Sa |
Anti-cd19 antibodies and methods of use thereof
|
|
JP2020503015A
(ja)
*
|
2016-12-13 |
2020-01-30 |
カースゲン セラピューティクス リミテッドＣａｒｓｇｅｎ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｌｉｍｉｔｅｄ |
抗ｃｄ１９のヒト化抗体及びｃｄ１９を標的とする免疫エフェクター細胞
|
|
EP3609536B1
(en)
*
|
2017-01-05 |
2022-03-09 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Humanized anti-cd19 antibody and use thereof with chimeric antigen receptor
|
|
CN110462040A
(zh)
|
2017-01-10 |
2019-11-15 |
英特拉克森公司 |
通过新基因开关表达系统调节多肽的表达
|
|
WO2018152452A1
(en)
|
2017-02-17 |
2018-08-23 |
Mapp Biopharmaceutical, Inc. |
Monoclonal antibodies and cocktails for treatment of ebola infections
|
|
EP3585402B1
(en)
|
2017-02-27 |
2024-03-06 |
Juno Therapeutics, Inc. |
Compositions, articles of manufacture and methods related to dosing in cell therapy
|
|
WO2018170188A2
(en)
|
2017-03-14 |
2018-09-20 |
Juno Therapeutics, Inc. |
Methods for cryogenic storage
|
|
RU2019128544A
(ru)
|
2017-03-27 |
2021-04-28 |
Нэшнл Юниверсити Оф Сингапур |
Линии стимулирующих клеток для ex vivo размножения и активации клеток-натуральных киллеров
|
|
BR112019019917A2
(pt)
|
2017-03-27 |
2020-04-22 |
Nat Univ Singapore |
receptores quiméricos nkg2d truncados e seus usos em imunoterapia de células exterminadoras naturais
|
|
JP7664680B2
(ja)
|
2017-03-29 |
2025-04-18 |
リガケム バイオサイエンシズ， インク． |
ピロロベンゾジアゼピン二量体前駆体及びそのリガンド－リンカーコンジュゲート化合物
|
|
JOP20180040A1
(ar)
|
2017-04-20 |
2019-01-30 |
Gilead Sciences Inc |
مثبطات pd-1/pd-l1
|
|
JOP20180042A1
(ar)
*
|
2017-04-24 |
2019-01-30 |
Kite Pharma Inc |
نطاقات ربط مولد ضد متوافقة مع البشر وطرق الاستخدام
|
|
CN111225675B
(zh)
|
2017-06-02 |
2024-05-03 |
朱诺治疗学股份有限公司 |
使用过继细胞疗法治疗的制品和方法
|
|
EP4681734A2
(en)
|
2017-06-07 |
2026-01-21 |
Precigen, Inc. |
Expression of novel cell tags
|
|
EP3441471A1
(en)
*
|
2017-08-08 |
2019-02-13 |
CEVEC Pharmaceuticals GmbH |
Use of constitutively active variants of growth factor receptors as selection makers for the generation of stable producer cell lines
|
|
BR112020001605A2
(pt)
|
2017-08-09 |
2020-08-11 |
Juno Therapeutics Inc |
métodos para produzir composições de células geneticamente modificadas e composições relacionadas
|
|
MA49981A
(fr)
|
2017-08-09 |
2020-06-17 |
Juno Therapeutics Inc |
Procédés et compositions de préparation de cellules génétiquement modifiées
|
|
EP3676403A1
(en)
|
2017-09-01 |
2020-07-08 |
Juno Therapeutics, Inc. |
Gene expression and assessment of risk of developing toxicity following cell therapy
|
|
EP3679370A1
(en)
|
2017-09-07 |
2020-07-15 |
Juno Therapeutics, Inc. |
Methods of identifying cellular attributes related to outcomes associated with cell therapy
|
|
WO2019055399A1
(en)
*
|
2017-09-12 |
2019-03-21 |
Igc Bio, Inc. |
ANTI-VEGF ANTIBODIES
|
|
ES2960419T3
(es)
|
2017-09-15 |
2024-03-04 |
Lentigen Tech Inc |
Composiciones y métodos de tratamiento de cáncer con inmunoterapia anti-CD19
|
|
US20200230221A1
(en)
|
2017-09-19 |
2020-07-23 |
Massachusetts Institute Of Technology |
Compositions for chimeric antigen receptor t cell therapy and uses thereof
|
|
BR112020005676A2
(pt)
|
2017-09-22 |
2020-10-20 |
WuXi Biologics Ireland Limited |
novos complexos polipeptídicos biespecíficos
|
|
US11365254B2
(en)
|
2017-09-22 |
2022-06-21 |
WuXi Biologics Ireland Limited |
Bispecific CD3/CD19 polypeptide complexes
|
|
JP7095078B2
(ja)
*
|
2017-09-22 |
2022-07-04 |
カイト ファーマ インコーポレイテッド |
キメラポリペプチド及びその使用
|
|
CN107759700A
(zh)
*
|
2017-10-18 |
2018-03-06 |
银丰生物工程集团有限公司 |
靶向cd19抗原的转基因t细胞及其制备方法与应用
|
|
CN107759699A
(zh)
*
|
2017-10-18 |
2018-03-06 |
银丰生物工程集团有限公司 |
靶向cd30抗原的转基因t细胞及其制备方法与应用
|
|
US12258580B2
(en)
|
2017-11-01 |
2025-03-25 |
Juno Therapeutics, Inc. |
Process for generating therapeutic compositions of engineered cells
|
|
US12031975B2
(en)
|
2017-11-01 |
2024-07-09 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
|
WO2019089848A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Methods associated with tumor burden for assessing response to a cell therapy
|
|
BR112020008565A2
(pt)
|
2017-11-01 |
2020-10-20 |
Juno Therapeutics Inc |
processo para a produção de uma composição de célula t
|
|
US11760806B2
(en)
|
2017-11-03 |
2023-09-19 |
Sorrento Therapeutics, Inc. |
CD-38 directed chimeric antigen receptor constructs
|
|
US11826385B2
(en)
*
|
2017-11-10 |
2023-11-28 |
Jura Bio, Inc. |
Major histocompatibility complex-based chimeric receptors and uses thereof for treating autoimmune diseases
|
|
EP3716980A1
(en)
|
2017-12-01 |
2020-10-07 |
Juno Therapeutics, Inc. |
Methods for dosing and for modulation of genetically engineered cells
|
|
CA3083936C
(en)
*
|
2017-12-06 |
2022-08-23 |
Abclon Inc. |
Anti-cd19 antibody or antigen-binding fragment and cd19-specific chimeric antigen receptor comprising the same
|
|
BR112020011223A2
(pt)
|
2017-12-08 |
2020-11-17 |
Juno Therapeutics Inc |
marcadores fenotípicos para terapia celular e mé-todos relacionados
|
|
MX2020005908A
(es)
|
2017-12-08 |
2020-10-07 |
Juno Therapeutics Inc |
Proceso para producir una composicion de celulas t modificadas.
|
|
MA51105A
(fr)
|
2017-12-08 |
2020-10-14 |
Juno Therapeutics Inc |
Formulation de milieux sans sérum pour la culture de cellules et ses procédés d'utilisation
|
|
AU2018392213B2
(en)
|
2017-12-20 |
2021-03-04 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3' cyclic dinucleotides with phosphonate bond activating the STING adaptor protein
|
|
AU2018392212B9
(en)
|
2017-12-20 |
2021-03-18 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3' cyclic dinucleotides with phosphonate bond activating the STING adaptor protein
|
|
EP3730519B1
(en)
*
|
2017-12-22 |
2023-09-13 |
AbClon Inc. |
Antibody or antigen-binding fragment thereof that specifically recognizes b cell malignancies, chimeric antigen receptor comprising same, and uses thereof
|
|
CN107903326B
(zh)
*
|
2018-01-02 |
2020-06-30 |
广东省人民医院(广东省医学科学院) |
包含C3aR胞内结构域的嵌合抗原受体、慢病毒载体、表达细胞及药物
|
|
CN108047332B
(zh)
*
|
2018-01-15 |
2021-08-24 |
阿思科力(苏州)生物科技有限公司 |
以cd19为靶点的特异性抗体、car-nk细胞及其制备和应用
|
|
JP7383620B2
(ja)
|
2018-01-31 |
2023-11-20 |
セルジーン コーポレイション |
養子細胞療法およびチェックポイント阻害剤を使用する併用療法
|
|
AU2019219454A1
(en)
|
2018-02-09 |
2020-08-27 |
National University Of Singapore |
Activating chimeric receptors and uses thereof in natural killer cell immunotherapy
|
|
KR102586510B1
(ko)
|
2018-02-13 |
2023-10-12 |
길리애드 사이언시즈, 인코포레이티드 |
Pd-1/pd-l1 억제제
|
|
MX2020009463A
(es)
*
|
2018-03-14 |
2021-03-09 |
Seattle Childrens Hospital Dba Seattle Childrens Res Inst |
Receptor de antígeno quimérico de receptor de il-13 alfa 2 (il13ra2) para inmunoterapia de células t específica para tumor.
|
|
US12258378B2
(en)
*
|
2018-03-14 |
2025-03-25 |
Dana-Farber Cancer Institute, Inc. |
Engineered cells, T cell immune modulating antibodies and methods for using the same
|
|
US12441787B2
(en)
|
2018-04-02 |
2025-10-14 |
National University Of Singapore |
Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells
|
|
TW202005654A
(zh)
|
2018-04-06 |
2020-02-01 |
捷克科學院有機化學與生物化學研究所 |
２，２，─環二核苷酸
|
|
TWI833744B
(zh)
|
2018-04-06 |
2024-03-01 |
捷克科學院有機化學與生物化學研究所 |
3'3'-環二核苷酸
|
|
TWI818007B
(zh)
|
2018-04-06 |
2023-10-11 |
捷克科學院有機化學與生物化學研究所 |
2'3'-環二核苷酸
|
|
US12215337B2
(en)
|
2018-04-12 |
2025-02-04 |
Umoja Biopharma, Inc. |
Viral vectors and packaging cell lines
|
|
AR114789A1
(es)
*
|
2018-04-18 |
2020-10-14 |
Hoffmann La Roche |
Anticuerpos anti-hla-g y uso de los mismos
|
|
AU2019255750B2
(en)
|
2018-04-19 |
2021-10-21 |
Gilead Sciences, Inc. |
PD-1/PD-L1 inhibitors
|
|
TW202014193A
(zh)
|
2018-05-03 |
2020-04-16 |
捷克科學院有機化學與生物化學研究所 |
包含碳環核苷酸之2’3’－環二核苷酸
|
|
BR112020022185A2
(pt)
|
2018-05-03 |
2021-02-02 |
Juno Therapeutics Inc |
terapia de combinação de uma terapia de células t do receptor de antígeno quimérico (car) e um inibidor de quinase
|
|
BR112020022299A2
(pt)
*
|
2018-05-09 |
2021-02-23 |
Legochem Biosciences, Inc. |
composições e métodos relacionados a conjugados de anticorpo-fármaco anti-cd19
|
|
EP3793565B1
(en)
|
2018-05-14 |
2022-01-05 |
Gilead Sciences, Inc. |
Mcl-1 inhibitors
|
|
AU2019301811B2
(en)
|
2018-07-13 |
2022-05-26 |
Gilead Sciences, Inc. |
PD-1/PD-L1 inhibitors
|
|
WO2020044239A1
(en)
|
2018-08-29 |
2020-03-05 |
National University Of Singapore |
A method to specifically stimulate survival and expansion of genetically-modified immune cells
|
|
JP7557882B2
(ja)
|
2018-09-28 |
2024-09-30 |
マサチューセッツ インスティテュート オブ テクノロジー |
コラーゲンに局在化される免疫調節分子およびその方法
|
|
WO2020072656A1
(en)
|
2018-10-03 |
2020-04-09 |
Gilead Sciences, Inc. |
Imidozopyrimidine derivatives
|
|
JP7158577B2
(ja)
|
2018-10-24 |
2022-10-21 |
ギリアード サイエンシーズ， インコーポレイテッド |
Ｐｄ－１／ｐｄ－ｌ１阻害剤
|
|
EP3874024A1
(en)
|
2018-10-31 |
2021-09-08 |
Juno Therapeutics GmbH |
Methods for selection and stimulation of cells and apparatus for same
|
|
SG11202103839UA
(en)
|
2018-10-31 |
2021-05-28 |
Gilead Sciences Inc |
Substituted 6-azabenzimidazole compounds as hpk1 inhibitors
|
|
KR102658602B1
(ko)
|
2018-10-31 |
2024-04-19 |
길리애드 사이언시즈, 인코포레이티드 |
Hpk1 억제 활성을 갖는 치환된 6-아자벤즈이미다졸 화합물
|
|
KR20210100624A
(ko)
|
2018-11-06 |
2021-08-17 |
주노 쎄러퓨티크스 인코퍼레이티드 |
유전적으로 조작된 ｔ 세포를 제조하는 방법
|
|
CA3118830A1
(en)
*
|
2018-11-07 |
2020-05-14 |
Crispr Therapeutics Ag |
Anti-ptk7 immune cell cancer therapy
|
|
EP3880238A1
(en)
|
2018-11-16 |
2021-09-22 |
Juno Therapeutics, Inc. |
Methods of dosing engineered t cells for the treatment of b cell malignancies
|
|
MX2021006238A
(es)
|
2018-11-30 |
2021-10-01 |
Juno Therapeutics Inc |
Metodos para tratamiento que usan terapia celular adoptiva.
|
|
IL283298B2
(en)
|
2018-11-30 |
2025-03-01 |
Juno Therapeutics Inc |
Methods for dosing and treating B-cell malignancies with adoptive cell therapy
|
|
WO2020114358A1
(zh)
*
|
2018-12-03 |
2020-06-11 |
广东东阳光药业有限公司 |
Cd19抗体及其应用
|
|
IL316392A
(en)
|
2018-12-12 |
2024-12-01 |
Kite Pharma Inc |
Chimeric antigen receptors and CAR-T cells and methods of use
|
|
CN109734813B
(zh)
|
2019-01-28 |
2022-06-17 |
广东昭泰体内生物医药科技有限公司 |
一种嵌合抗原受体及其应用
|
|
US12241061B2
(en)
|
2019-02-04 |
2025-03-04 |
National University Corporation Ehime University |
CAR library and scFv manufacturing method
|
|
JP7593646B2
(ja)
|
2019-02-20 |
2024-12-03 |
シティ・オブ・ホープ |
Ｂａｆｆ－ｒ／ｃｄ１９を標的としたキメラ抗原受容体修飾ｔ細胞とその使用
|
|
WO2020180882A1
(en)
|
2019-03-05 |
2020-09-10 |
Nkarta, Inc. |
Cd19-directed chimeric antigen receptors and uses thereof in immunotherapy
|
|
CA3129022C
(en)
|
2019-03-07 |
2023-08-01 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3'-cyclic dinucleotides and prodrugs thereof
|
|
EP3935065A1
(en)
|
2019-03-07 |
2022-01-12 |
Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. |
3'3'-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator
|
|
CA3129011C
(en)
|
2019-03-07 |
2023-12-19 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3'-cyclic dinucleotides and prodrugs thereof
|
|
US20230065784A1
(en)
|
2019-03-21 |
2023-03-02 |
City Of Hope |
Composition and method for reducing expression of checkpoint inhibitors in t cells expressing a car or ctl
|
|
TW202210480A
(zh)
|
2019-04-17 |
2022-03-16 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TWI751517B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
SG11202111372VA
(en)
|
2019-05-01 |
2021-11-29 |
Juno Therapeutics Inc |
Cells expressing a chimeric receptor from a modified cd247 locus, related polynucleotides and methods
|
|
US11453681B2
(en)
|
2019-05-23 |
2022-09-27 |
Gilead Sciences, Inc. |
Substituted eneoxindoles and uses thereof
|
|
JP2022537700A
(ja)
|
2019-06-12 |
2022-08-29 |
ジュノー セラピューティクス インコーポレイテッド |
細胞媒介細胞傷害性療法と生存促進性ｂｃｌ２ファミリータンパク質の阻害剤との併用療法
|
|
WO2020253879A1
(zh)
*
|
2019-06-21 |
2020-12-24 |
甘李药业股份有限公司 |
一种双特异性嵌合抗原受体
|
|
CN114245807B
(zh)
|
2019-06-25 |
2025-05-02 |
吉利德科学公司 |
Flt3l-fc融合蛋白和使用方法
|
|
WO2020263399A1
(en)
|
2019-06-26 |
2020-12-30 |
Massachusetts Institute Of Technology |
Immunomodulatory fusion protein-metal hydroxide complexes and methods thereof
|
|
CN112210007B
(zh)
*
|
2019-07-11 |
2022-07-12 |
华夏英泰（北京）生物技术有限公司 |
一种cd19抗原高亲和力的抗体以及包含其cd19单链抗体区的嵌合抗原受体
|
|
WO2021016062A1
(en)
*
|
2019-07-19 |
2021-01-28 |
The Children's Hospital Of Philadelphia |
Chimeric antigen receptors containing glypican 2 binding domains
|
|
EP3769816A1
(en)
*
|
2019-07-25 |
2021-01-27 |
Ospedale Pediatrico Bambino Gesù |
Car-cd123 vector and uses thereof
|
|
US20220298222A1
(en)
|
2019-08-22 |
2022-09-22 |
Juno Therapeutics, Inc. |
Combination therapy of a t cell therapy and an enhancer of zeste homolog 2 (ezh2) inhibitor and related methods
|
|
KR20210028544A
(ko)
|
2019-09-04 |
2021-03-12 |
주식회사 레고켐 바이오사이언스 |
인간 ror1에 대한 항체를 포함하는 항체 약물 접합체 및 이의 용도
|
|
WO2021061648A1
(en)
|
2019-09-23 |
2021-04-01 |
Massachusetts Institute Of Technology |
Methods and compositions for stimulation of endogenous t cell responses
|
|
EP4038194A1
(en)
|
2019-10-04 |
2022-08-10 |
Ultragenyx Pharmaceutical Inc. |
Methods for improved therapeutic use of recombinant aav
|
|
PH12022550835A1
(en)
|
2019-10-18 |
2023-07-03 |
Forty Seven Inc |
Combination therapies for treating myelodysplastic syndromes and acute myeloid leukemia
|
|
BR112022008023A2
(pt)
|
2019-10-30 |
2022-07-12 |
Juno Therapeutics Gmbh |
Dispositivos de seleção e/ou estimulação de células e métodos de uso
|
|
AU2020375149A1
(en)
*
|
2019-10-31 |
2022-05-12 |
Incyte Corporation |
Sequential anti-CD19 therapy
|
|
MY209360A
(en)
|
2019-10-31 |
2025-07-03 |
Forty Seven Llc |
Anti-cd47 and anti-cd20 based treatment of blood cancer
|
|
EP4054623A1
(en)
|
2019-11-07 |
2022-09-14 |
Juno Therapeutics, Inc. |
Combination of a t cell therapy and (s)-3-[4-(4-morpholin-4 ylmethyl-benzyloxy)-l-oxo-l,3-dihydro-isoindol-2-yl]- piperidine-2,6-dione
|
|
TWI778443B
(zh)
|
2019-11-12 |
2022-09-21 |
美商基利科學股份有限公司 |
Mcl1抑制劑
|
|
KR20220132527A
(ko)
|
2019-12-06 |
2022-09-30 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Ｂ 세포 악성 종양을 치료하기 위한 세포 요법과 연관된 독성 및 반응과 관련된 방법
|
|
CN117736207A
(zh)
|
2019-12-24 |
2024-03-22 |
卡尔那生物科学株式会社 |
二酰基甘油激酶调节化合物
|
|
CA3165346A1
(en)
|
2020-01-23 |
2021-07-29 |
George Q. Daley |
Stroma-free t cell differentiation from human pluripotent stem cells
|
|
IL294724A
(en)
|
2020-01-24 |
2022-09-01 |
Juno Therapeutics Inc |
Methods for dosing and treatment of follicular lymphoma and marginal zone lymphoma in adoptive cell therapy
|
|
WO2021154887A1
(en)
|
2020-01-28 |
2021-08-05 |
Juno Therapeutics, Inc. |
Methods for t cell transduction
|
|
CN115768443A
(zh)
|
2020-02-12 |
2023-03-07 |
朱诺治疗学股份有限公司 |
Cd19定向嵌合抗原受体t细胞组合物和方法及其用途
|
|
AU2021219668B2
(en)
|
2020-02-14 |
2025-06-12 |
Gilead Sciences, Inc. |
Antibodies and fusion proteins that bind to CCR8 and uses thereof
|
|
EP4117716A2
(en)
|
2020-03-10 |
2023-01-18 |
Massachusetts Institute of Technology |
Methods for generating engineered memory-like nk cells and compositions thereof
|
|
US11896619B2
(en)
|
2020-03-10 |
2024-02-13 |
Massachusetts Institute Of Technology |
Compositions and methods for immunotherapy of NPM1c-positive cancer
|
|
CN113402612A
(zh)
|
2020-03-17 |
2021-09-17 |
西比曼生物科技（香港）有限公司 |
靶向cd19和cd20的联合嵌合抗原受体及其应用
|
|
WO2021221782A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Chimeric antigen receptor-targeting ligands and uses thereof
|
|
WO2021221783A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
|
CA3181922A1
(en)
|
2020-05-01 |
2021-11-04 |
Gilead Sciences, Inc. |
Cd73 inhibiting 2,4-dioxopyrimidine compounds
|
|
US20230178239A1
(en)
|
2020-05-13 |
2023-06-08 |
Juno Therapeutics, Inc. |
Methods of identifying features associated with clinical response and uses thereof
|
|
CN115835873A
(zh)
|
2020-05-13 |
2023-03-21 |
朱诺治疗学股份有限公司 |
用于产生表达重组受体的供体分批细胞的方法
|
|
JP2023531531A
(ja)
|
2020-06-26 |
2023-07-24 |
ジュノ セラピューティクス ゲーエムベーハー |
組換え受容体を条件付きで発現する操作されたｔ細胞、関連ポリヌクレオチド、および方法
|
|
EP4178678A1
(en)
|
2020-07-07 |
2023-05-17 |
Cancure, LLC |
Mic antibodies and binding agents and methods of using the same
|
|
JP2023549780A
(ja)
|
2020-11-04 |
2023-11-29 |
ジュノー セラピューティクス インコーポレイテッド |
改変されたインバリアントｃｄ３免疫グロブリンスーパーファミリー鎖遺伝子座からキメラ受容体を発現する細胞ならびに関連するポリヌクレオチドおよび方法
|
|
WO2022105811A1
(zh)
|
2020-11-20 |
2022-05-27 |
江苏先声药业有限公司 |
Cd19人源化抗体及其应用
|
|
EP4251742A4
(en)
|
2020-11-24 |
2025-01-08 |
Lyell Immunopharma, Inc. |
METHODS OF MAKING, COMPOSITIONS COMPRISING, AND METHODS OF USING REGENERATED T CELLS
|
|
WO2022133030A1
(en)
|
2020-12-16 |
2022-06-23 |
Juno Therapeutics, Inc. |
Combination therapy of a cell therapy and a bcl2 inhibitor
|
|
WO2022133169A1
(en)
|
2020-12-18 |
2022-06-23 |
Century Therapeutics, Inc. |
Chimeric antigen receptor systems with adaptable receptor specificity
|
|
KR20230137340A
(ko)
|
2020-12-30 |
2023-10-04 |
알로노스 테라퓨틱스 인코포레이티드 |
폴리시스트로닉 발현 카세트를 포함하는 재조합 벡터및 이의 사용 방법
|
|
AU2022206324A1
(en)
|
2021-01-11 |
2023-07-20 |
Sana Biotechnology, Inc. |
Use of cd8-targeted viral vectors
|
|
JP2024509853A
(ja)
|
2021-03-03 |
2024-03-05 |
ジュノー セラピューティクス インコーポレイテッド |
Ｔ細胞療法およびｄｇｋ阻害剤の組合せ
|
|
KR20230158573A
(ko)
|
2021-03-22 |
2023-11-20 |
주노 쎄러퓨티크스 인코퍼레이티드 |
바이러스 벡터 입자의 효력을 평가하는 방법
|
|
AU2022241654A1
(en)
|
2021-03-22 |
2023-09-28 |
Juno Therapeutics, Inc. |
Methods of determining potency of a therapeutic cell composition
|
|
JP2024514245A
(ja)
|
2021-03-29 |
2024-03-29 |
ジュノー セラピューティクス インコーポレイテッド |
チェックポイント阻害剤療法とｃａｒ ｔ細胞療法との組合せを用いた投薬および処置のための方法
|
|
EP4313126A1
(en)
|
2021-03-29 |
2024-02-07 |
Juno Therapeutics, Inc. |
Combination of a car t cell therapy and an immunomodulatory compound for treatment of lymphoma
|
|
TW202302145A
(zh)
|
2021-04-14 |
2023-01-16 |
美商基利科學股份有限公司 |
ＣＤ４７／ＳＩＲＰα結合及ＮＥＤＤ８活化酶Ｅ１調節次單元之共抑制以用於治療癌症
|
|
US20250283037A1
(en)
|
2021-05-06 |
2025-09-11 |
Juno Therapeutics Gmbh |
Methods for stimulating and transducing t cells
|
|
US20220389394A1
(en)
|
2021-05-18 |
2022-12-08 |
Gilead Sciences, Inc. |
METHODS OF USING FLT3L-Fc FUSION PROTEINS
|
|
KR20240005901A
(ko)
|
2021-06-23 |
2024-01-12 |
길리애드 사이언시즈, 인코포레이티드 |
디아실글리세롤 키나제 조절 화합물
|
|
KR20240025616A
(ko)
|
2021-06-23 |
2024-02-27 |
길리애드 사이언시즈, 인코포레이티드 |
다이아실글리세롤 키나제 조절 화합물
|
|
JP7654118B2
(ja)
|
2021-06-23 |
2025-03-31 |
ギリアード サイエンシーズ， インコーポレイテッド |
ジアシルグリセロールキナーゼ調節化合物
|
|
AU2022298639C1
(en)
|
2021-06-23 |
2025-07-17 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
|
CN117616048A
(zh)
*
|
2021-07-09 |
2024-02-27 |
先声再明医药有限公司 |
Cd19抗体及其应用
|
|
US20240342215A1
(en)
|
2021-07-14 |
2024-10-17 |
Regeneron Pharmaceuticals, Inc. |
Engineered t cell receptors fused to binding domains from antibodies
|
|
JP2024528981A
(ja)
|
2021-08-04 |
2024-08-01 |
サナ バイオテクノロジー，インコーポレイテッド |
Ｃｄ４標的化ウイルスベクターの使用
|
|
EP4381050A4
(en)
*
|
2021-08-06 |
2025-10-08 |
Seattle Childrens Hospital D/B/A Seattle Childrens Res Institute |
T CELL MANUFACTURING PROCESSES
|
|
JP2024538116A
(ja)
*
|
2021-10-18 |
2024-10-18 |
カイト ファーマ インコーポレイテッド |
キメラ抗原受容体のシグナル伝達ドメイン
|
|
CN118139858A
(zh)
|
2021-10-28 |
2024-06-04 |
吉利德科学公司 |
吡地嗪-3(2h)-酮衍生物
|
|
WO2023077030A1
(en)
|
2021-10-29 |
2023-05-04 |
Gilead Sciences, Inc. |
Cd73 compounds
|
|
WO2023081715A1
(en)
|
2021-11-03 |
2023-05-11 |
Viracta Therapeutics, Inc. |
Combination of car t-cell therapy with btk inhibitors and methods of use thereof
|
|
EP4448775A1
(en)
|
2021-12-17 |
2024-10-23 |
Sana Biotechnology, Inc. |
Modified paramyxoviridae attachment glycoproteins
|
|
TW202342498A
(zh)
|
2021-12-17 |
2023-11-01 |
美商薩那生物科技公司 |
經修飾副黏液病毒科融合醣蛋白
|
|
EP4452414A2
(en)
|
2021-12-22 |
2024-10-30 |
Gilead Sciences, Inc. |
Ikaros zinc finger family degraders and uses thereof
|
|
WO2023122615A1
(en)
|
2021-12-22 |
2023-06-29 |
Gilead Sciences, Inc. |
Ikaros zinc finger family degraders and uses thereof
|
|
TW202340168A
(zh)
|
2022-01-28 |
2023-10-16 |
美商基利科學股份有限公司 |
Ｐａｒｐ７抑制劑
|
|
JP2025504002A
(ja)
|
2022-01-28 |
2025-02-06 |
ジュノー セラピューティクス インコーポレイテッド |
細胞組成物を製造する方法
|
|
EP4472646A1
(en)
|
2022-02-01 |
2024-12-11 |
Sana Biotechnology, Inc. |
Cd3-targeted lentiviral vectors and uses thereof
|
|
ES2999273T3
(en)
|
2022-03-17 |
2025-02-25 |
Gilead Sciences Inc |
Ikaros zinc finger family degraders and uses thereof
|
|
CN119031937A
(zh)
|
2022-03-24 |
2024-11-26 |
吉利德科学公司 |
用于治疗表达Trop-2的癌症的联合疗法
|
|
JP2025510415A
(ja)
*
|
2022-03-28 |
2025-04-14 |
ヴァイジェン－バイオ，インコーポレイテッド |
養子細胞療法用の遺伝的に操作された抗体抵抗性（ｇｅａｒ）細胞
|
|
US20250222027A1
(en)
|
2022-04-01 |
2025-07-10 |
Sana Biotechnology, Inc. |
Cytokine receptor agonist and viral vector combination therapies
|
|
TWI876305B
(zh)
|
2022-04-05 |
2025-03-11 |
美商基利科學股份有限公司 |
用於治療結腸直腸癌之組合療法
|
|
AU2023251117A1
(en)
|
2022-04-08 |
2024-11-21 |
Regeneron Pharmaceuticals, Inc. |
Multipartite receptor and signaling complexes
|
|
CN114716558B
(zh)
*
|
2022-04-12 |
2023-05-05 |
骏蓦(北京)生物科技有限公司 |
一种双特异性抗体及其治疗癌症的应用
|
|
KR20250004824A
(ko)
|
2022-04-21 |
2025-01-08 |
길리애드 사이언시즈, 인코포레이티드 |
Kras g12d 조절 화합물
|
|
US20250297282A1
(en)
|
2022-05-05 |
2025-09-25 |
Juno Therapeutics Gmbh |
Viral-binding protein and related reagents, articles, and methods of use
|
|
WO2023220655A1
(en)
|
2022-05-11 |
2023-11-16 |
Celgene Corporation |
Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy
|
|
IL316839A
(en)
|
2022-05-17 |
2025-01-01 |
Umoja Biopharma Inc |
Production of viral particles
|
|
WO2023230581A1
(en)
|
2022-05-25 |
2023-11-30 |
Celgene Corporation |
Methods of manufacturing t cell therapies
|
|
WO2023250400A1
(en)
|
2022-06-22 |
2023-12-28 |
Juno Therapeutics, Inc. |
Treatment methods for second line therapy of cd19-targeted car t cells
|
|
EP4547230A1
(en)
|
2022-06-29 |
2025-05-07 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids
|
|
IL317958A
(en)
|
2022-07-01 |
2025-02-01 |
Gilead Sciences Inc |
CD73 compounds
|
|
CN120152717A
(zh)
|
2022-09-08 |
2025-06-13 |
朱诺治疗学股份有限公司 |
T细胞疗法和连续或间歇dgk抑制剂给药的组合
|
|
US20240091351A1
(en)
|
2022-09-21 |
2024-03-21 |
Gilead Sciences, Inc. |
FOCAL IONIZING RADIATION AND CD47/SIRPa DISRUPTION ANTICANCER COMBINATION THERAPY
|
|
EP4602174A1
(en)
|
2022-10-13 |
2025-08-20 |
Sana Biotechnology, Inc. |
Viral particles targeting hematopoietic stem cells
|
|
JP2026500897A
(ja)
|
2022-11-04 |
2026-01-09 |
ウモジャ バイオファーマ インコーポレイテッド |
融合分子を呈示するレンチウイルス粒子およびその使用
|
|
WO2024097992A2
(en)
|
2022-11-04 |
2024-05-10 |
Umoja Biopharma, Inc. |
Particles displaying adhesion-molecule fusions
|
|
EP4615960A1
(en)
|
2022-11-09 |
2025-09-17 |
C3S2 GmbH |
Methods for manufacturing engineered immune cells
|
|
KR20250135354A
(ko)
|
2022-12-13 |
2025-09-12 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Baff-r 및 cd19에 특이적인 키메라 항원 수용체 및 그의 방법 및 용도
|
|
US20240254118A1
(en)
|
2022-12-22 |
2024-08-01 |
Gilead Sciences, Inc. |
Prmt5 inhibitors and uses thereof
|
|
JP2026504491A
(ja)
|
2023-02-03 |
2026-02-05 |
ツェー３エス２ ゲーエムベーハー |
操作された免疫細胞の非ウイルス的製造のための方法
|
|
TW202502363A
(zh)
|
2023-02-28 |
2025-01-16 |
美商奇諾治療有限公司 |
用於治療全身性自體免疫疾病之細胞療法
|
|
EP4626447A4
(en)
|
2023-03-31 |
2026-02-18 |
Abelzeta Inc |
BISPECIFIC CHIMERIC ANTIGENIC RECEPTORS TARGETING CD20 AND BCMA
|
|
EP4695260A1
(en)
|
2023-04-11 |
2026-02-18 |
Gilead Sciences, Inc. |
Kras modulating compounds
|
|
WO2024220560A1
(en)
|
2023-04-18 |
2024-10-24 |
Sana Biotechnology, Inc. |
Engineered protein g fusogens and related lipid particles and methods thereof
|
|
WO2024220598A2
(en)
|
2023-04-18 |
2024-10-24 |
Sana Biotechnology, Inc. |
Lentiviral vectors with two or more genomes
|
|
KR20250169631A
(ko)
|
2023-04-18 |
2025-12-03 |
주노 쎄러퓨티크스 인코퍼레이티드 |
치료 세포 조성물의 효력을 평가하기 위한 세포독성 검정
|
|
WO2024220574A1
(en)
|
2023-04-18 |
2024-10-24 |
Sana Biotechnology, Inc. |
Universal protein g fusogens and adapter systems thereof and related lipid particles and uses
|
|
KR20250175331A
(ko)
|
2023-04-21 |
2025-12-16 |
길리애드 사이언시즈, 인코포레이티드 |
Prmt5 억제제 및 이의 용도
|
|
WO2024226858A1
(en)
|
2023-04-26 |
2024-10-31 |
Juno Therapeutics, Inc. |
Methods for viral vector manufacturing
|
|
WO2024243365A2
(en)
|
2023-05-23 |
2024-11-28 |
Juno Therapeutics, Inc. |
Activation markers of t cells and method for assessing t cell activation
|
|
US20250042922A1
(en)
|
2023-06-30 |
2025-02-06 |
Gilead Sciences, Inc. |
Kras modulating compounds
|
|
US20250066328A1
(en)
|
2023-07-26 |
2025-02-27 |
Gilead Sciences, Inc. |
Parp7 inhibitors
|
|
AU2024297978A1
(en)
|
2023-07-26 |
2026-02-05 |
Gilead Sciences, Inc. |
Parp7 inhibitors
|
|
WO2025054202A1
(en)
|
2023-09-05 |
2025-03-13 |
Sana Biotechnology, Inc. |
Method of screening a sample comprising a transgene with a unique barcode
|
|
US20250101042A1
(en)
|
2023-09-08 |
2025-03-27 |
Gilead Sciences, Inc. |
Kras g12d modulating compounds
|
|
US20250109147A1
(en)
|
2023-09-08 |
2025-04-03 |
Gilead Sciences, Inc. |
Kras g12d modulating compounds
|
|
WO2025059162A1
(en)
|
2023-09-11 |
2025-03-20 |
Dana-Farber Cancer Institute, Inc. |
Car-engager containing il-2 variants to enhance the functionality of car t cells
|
|
WO2025096589A1
(en)
|
2023-11-03 |
2025-05-08 |
Gilead Sciences, Inc. |
Prmt5 inhibitors and uses thereof
|
|
WO2025137640A1
(en)
|
2023-12-22 |
2025-06-26 |
Gilead Sciences, Inc. |
Azaspiro wrn inhibitors
|
|
WO2025147545A1
(en)
|
2024-01-03 |
2025-07-10 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids and related methods and uses
|
|
WO2025151838A1
(en)
|
2024-01-12 |
2025-07-17 |
Sana Biotechnology, Inc. |
Safety switches to control in vitro and in vivo proliferation of cell therapy products
|
|
WO2025171383A2
(en)
|
2024-02-09 |
2025-08-14 |
Dispatch Biotherapeutics, Inc. |
Engineered cancer antigens and related methods and uses
|
|
WO2025171388A1
(en)
|
2024-02-09 |
2025-08-14 |
Dispatch Biotherapeutics, Inc. |
Engineered cancer antigens with modified domains and related methods and uses
|
|
WO2025231174A1
(en)
|
2024-04-30 |
2025-11-06 |
Umoja Biopharma, Inc. |
Manufacturing viral particles
|
|
WO2025235604A1
(en)
|
2024-05-08 |
2025-11-13 |
Umoja Biopharma, Inc. |
Fusion protein for use as immune cell engager
|
|
WO2025235851A1
(en)
|
2024-05-10 |
2025-11-13 |
Juno Therapeutics, Inc. |
Genetically engineered t cells expressing a cd19 chimeric antigen receptor (car) and uses thereof for allogeneic cell therapy
|
|
WO2025245003A1
(en)
|
2024-05-21 |
2025-11-27 |
Gilead Sciences, Inc. |
Prmt5 inhibitors and uses thereof
|
|
WO2026020055A2
(en)
|
2024-07-18 |
2026-01-22 |
Juno Therapeutics, Inc. |
Methods for assessing exosomes in a cell composition and related uses
|
|
WO2026020171A2
(en)
|
2024-07-19 |
2026-01-22 |
Aera Therapeutics, Inc. |
Chimeric antigen receptor constructs
|
|
WO2026025092A1
(en)
|
2024-07-26 |
2026-01-29 |
Juno Therapeutics, Inc. |
Synthetic promoters for t cell expression
|