|
FR7461M
(https=)
|
1968-06-19 |
1970-01-05 |
|
|
|
GB1355961A
(en)
|
1970-02-27 |
1974-06-12 |
Wellcome Found |
Preparation of immunosuppressive antilymphocytic serum
|
|
CH594444A5
(https=)
|
1972-12-04 |
1978-01-13 |
Gerd Birrenbach |
|
|
US3996355A
(en)
|
1975-01-02 |
1976-12-07 |
American Home Products Corporation |
Permanent suspension pharmaceutical dosage form
|
|
DK143689C
(da)
|
1975-03-20 |
1982-03-15 |
J Kreuter |
Fremgangsmaade til fremstilling af en adsorberet vaccine
|
|
US4756907A
(en)
|
1978-10-17 |
1988-07-12 |
Stolle Research & Development Corp. |
Active/passive immunization of the internal female reproductive organs
|
|
US4946929A
(en)
|
1983-03-22 |
1990-08-07 |
Massachusetts Institute Of Technology |
Bioerodible articles useful as implants and prostheses having predictable degradation rates
|
|
US6309669B1
(en)
|
1984-03-16 |
2001-10-30 |
The United States Of America As Represented By The Secretary Of The Army |
Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix
|
|
US4638045A
(en)
|
1985-02-19 |
1987-01-20 |
Massachusetts Institute Of Technology |
Non-peptide polyamino acid bioerodible polymers
|
|
US4631211A
(en)
|
1985-03-25 |
1986-12-23 |
Scripps Clinic & Research Foundation |
Means for sequential solid phase organic synthesis and methods using the same
|
|
US4806621A
(en)
|
1986-01-21 |
1989-02-21 |
Massachusetts Institute Of Technology |
Biocompatible, bioerodible, hydrophobic, implantable polyimino carbonate article
|
|
JPS63122620A
(ja)
|
1986-11-12 |
1988-05-26 |
Sanraku Inc |
ポリ乳酸マイクロスフエア及びその製造方法
|
|
US5736372A
(en)
|
1986-11-20 |
1998-04-07 |
Massachusetts Institute Of Technology |
Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure
|
|
CA1340581C
(en)
|
1986-11-20 |
1999-06-08 |
Joseph P. Vacanti |
Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
|
|
US5759830A
(en)
|
1986-11-20 |
1998-06-02 |
Massachusetts Institute Of Technology |
Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo
|
|
FR2608988B1
(fr)
|
1986-12-31 |
1991-01-11 |
Centre Nat Rech Scient |
Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules
|
|
US5912017A
(en)
|
1987-05-01 |
1999-06-15 |
Massachusetts Institute Of Technology |
Multiwall polymeric microspheres
|
|
US5229490A
(en)
|
1987-05-06 |
1993-07-20 |
The Rockefeller University |
Multiple antigen peptide system
|
|
US5019379A
(en)
|
1987-07-31 |
1991-05-28 |
Massachusetts Institute Of Technology |
Unsaturated polyanhydrides
|
|
US4950432A
(en)
|
1987-10-16 |
1990-08-21 |
Board Of Regents, The University Of Texas System |
Polyene microlide pre-liposomal powders
|
|
US6130082A
(en)
|
1988-05-05 |
2000-10-10 |
American Cyanamid Company |
Recombinant flagellin vaccines
|
|
US4929624A
(en)
|
1989-03-23 |
1990-05-29 |
Minnesota Mining And Manufacturing Company |
Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
|
|
US5010167A
(en)
|
1989-03-31 |
1991-04-23 |
Massachusetts Institute Of Technology |
Poly(amide-and imide-co-anhydride) for biological application
|
|
US5114703A
(en)
|
1989-05-30 |
1992-05-19 |
Alliance Pharmaceutical Corp. |
Percutaneous lymphography using particulate fluorocarbon emulsions
|
|
US5733572A
(en)
|
1989-12-22 |
1998-03-31 |
Imarx Pharmaceutical Corp. |
Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
|
|
US6005087A
(en)
|
1995-06-06 |
1999-12-21 |
Isis Pharmaceuticals, Inc. |
2'-modified oligonucleotides
|
|
US6399754B1
(en)
|
1991-12-24 |
2002-06-04 |
Isis Pharmaceuticals, Inc. |
Sugar modified oligonucleotides
|
|
GB9016885D0
(en)
|
1990-08-01 |
1990-09-12 |
Scras |
Sustained release pharmaceutical compositions
|
|
US6699474B1
(en)
|
1990-08-20 |
2004-03-02 |
Erich Hugo Cerny |
Vaccine and immunserum against drugs of abuse
|
|
US5175296A
(en)
|
1991-03-01 |
1992-12-29 |
Minnesota Mining And Manufacturing Company |
Imidazo[4,5-c]quinolin-4-amines and processes for their preparation
|
|
US5389640A
(en)
|
1991-03-01 |
1995-02-14 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
CA2289219C
(en)
|
1991-03-01 |
2003-05-20 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1h-imidazo[4,5-c]quinolin-4-amines
|
|
CA2084194C
(en)
|
1991-04-02 |
2003-05-20 |
Gregory John Russell-Jones |
Oral delivery systems for microparticles
|
|
US5811447A
(en)
|
1993-01-28 |
1998-09-22 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
|
IL105325A
(en)
|
1992-04-16 |
1996-11-14 |
Minnesota Mining & Mfg |
Immunogen/vaccine adjuvant composition
|
|
US6235313B1
(en)
|
1992-04-24 |
2001-05-22 |
Brown University Research Foundation |
Bioadhesive microspheres and their use as drug delivery and imaging systems
|
|
DK0671948T3
(da)
|
1992-06-25 |
1997-09-01 |
Smithkline Beecham Biolog |
Vaccinepræparat indeholdende adjuvanser
|
|
AU4778893A
(en)
|
1992-07-21 |
1994-02-14 |
General Hospital Corporation, The |
System of drug delivery to the lymphatic tissues
|
|
GB9216082D0
(en)
|
1992-07-28 |
1992-09-09 |
Univ Nottingham |
Lymphatic delivery composition
|
|
US6608201B2
(en)
|
1992-08-28 |
2003-08-19 |
3M Innovative Properties Company |
Process for preparing 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
FR2695563B1
(fr)
|
1992-09-11 |
1994-12-02 |
Pasteur Institut |
Microparticules portant des antigènes et leur utilisation pour l'induction de réponses humorales ou cellulaires.
|
|
AU4932493A
(en)
|
1992-09-25 |
1994-04-26 |
Dynagen, Inc. |
An immunobooster for delayed release of immunogen
|
|
US5399665A
(en)
|
1992-11-05 |
1995-03-21 |
Massachusetts Institute Of Technology |
Biodegradable polymers for cell transplantation
|
|
EP0678034B1
(en)
|
1993-01-11 |
1999-05-26 |
Dana Farber Cancer Institute |
Inducing cytotoxic t lymphocyte responses
|
|
US5512600A
(en)
|
1993-01-15 |
1996-04-30 |
Massachusetts Institute Of Technology |
Preparation of bonded fiber structures for cell implantation
|
|
US5395937A
(en)
|
1993-01-29 |
1995-03-07 |
Minnesota Mining And Manufacturing Company |
Process for preparing quinoline amines
|
|
US5514378A
(en)
|
1993-02-01 |
1996-05-07 |
Massachusetts Institute Of Technology |
Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures
|
|
ATE167396T1
(de)
|
1993-02-22 |
1998-07-15 |
Alza Corp |
Mittel zur oralen gabe von wirkstoffen
|
|
DE59403734D1
(de)
|
1993-03-17 |
1997-09-18 |
Silica Gel Gmbh |
Superparamagnetische teilchen, verfahren zu ihrer herstellung und verwendung derselben
|
|
CH686761A5
(de)
|
1993-05-27 |
1996-06-28 |
Sandoz Ag |
Galenische Formulierungen.
|
|
WO1995003035A1
(en)
|
1993-07-23 |
1995-02-02 |
Massachusetts Institute Of Technology |
Polymerized liposomes with enhanced stability for oral delivery
|
|
US5565215A
(en)
|
1993-07-23 |
1996-10-15 |
Massachusettes Institute Of Technology |
Biodegradable injectable particles for imaging
|
|
US5543158A
(en)
|
1993-07-23 |
1996-08-06 |
Massachusetts Institute Of Technology |
Biodegradable injectable nanoparticles
|
|
AU698962B2
(en)
|
1993-09-14 |
1998-11-12 |
Epimmune, Inc. |
Alteration of immune response using pan DR-binding peptides
|
|
US5798340A
(en)
|
1993-09-17 |
1998-08-25 |
Gilead Sciences, Inc. |
Nucleotide analogs
|
|
US5500161A
(en)
|
1993-09-21 |
1996-03-19 |
Massachusetts Institute Of Technology And Virus Research Institute |
Method for making hydrophobic polymeric microparticles
|
|
DE69529054T2
(de)
|
1994-02-28 |
2003-08-21 |
Nanopharm Ag |
System zur gezielten wirkstoffzufuhr, verfahren zu seiner herstellung und verwendung
|
|
US5596091A
(en)
|
1994-03-18 |
1997-01-21 |
The Regents Of The University Of California |
Antisense oligonucleotides comprising 5-aminoalkyl pyrimidine nucleotides
|
|
WO1995026204A1
(en)
|
1994-03-25 |
1995-10-05 |
Isis Pharmaceuticals, Inc. |
Immune stimulation by phosphorothioate oligonucleotide analogs
|
|
GB9412273D0
(en)
|
1994-06-18 |
1994-08-10 |
Univ Nottingham |
Administration means
|
|
ATE509102T1
(de)
|
1994-07-15 |
2011-05-15 |
Univ Iowa Res Found |
Immunomodulatorische oligonukleotide
|
|
US6207646B1
(en)
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6007845A
(en)
|
1994-07-22 |
1999-12-28 |
Massachusetts Institute Of Technology |
Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
|
|
US5716404A
(en)
|
1994-12-16 |
1998-02-10 |
Massachusetts Institute Of Technology |
Breast tissue engineering
|
|
EP0805678B1
(en)
|
1995-01-05 |
2003-10-29 |
THE BOARD OF REGENTS acting for and on behalf of THE UNIVERSITY OF MICHIGAN |
Surface-modified nanoparticles and method of making and using same
|
|
US5876727A
(en)
|
1995-03-31 |
1999-03-02 |
Immulogic Pharmaceutical Corporation |
Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same
|
|
US6123727A
(en)
|
1995-05-01 |
2000-09-26 |
Massachusetts Institute Of Technology |
Tissue engineered tendons and ligaments
|
|
US5866132A
(en)
|
1995-06-07 |
1999-02-02 |
Alberta Research Council |
Immunogenic oligosaccharide compositions
|
|
WO1997004747A1
(en)
|
1995-07-27 |
1997-02-13 |
Dunn James M |
Drug delivery systems for macromolecular drugs
|
|
EP0850051A2
(en)
|
1995-08-31 |
1998-07-01 |
Alkermes Controlled Therapeutics, Inc. |
Composition for sustained release of an agent
|
|
US6095148A
(en)
|
1995-11-03 |
2000-08-01 |
Children's Medical Center Corporation |
Neuronal stimulation using electrically conducting polymers
|
|
US5902599A
(en)
|
1996-02-20 |
1999-05-11 |
Massachusetts Institute Of Technology |
Biodegradable polymer networks for use in orthopedic and dental applications
|
|
US5874064A
(en)
|
1996-05-24 |
1999-02-23 |
Massachusetts Institute Of Technology |
Aerodynamically light particles for pulmonary drug delivery
|
|
US5898031A
(en)
|
1996-06-06 |
1999-04-27 |
Isis Pharmaceuticals, Inc. |
Oligoribonucleotides for cleaving RNA
|
|
AU6173196A
(en)
|
1996-06-10 |
1998-01-07 |
Cytos Pharmaceuticals Llc |
Imidazole derivatives as protective agents in reperfusion injury and severe inflammatory responses
|
|
US5922695A
(en)
|
1996-07-26 |
1999-07-13 |
Gilead Sciences, Inc. |
Antiviral phosphonomethyoxy nucleotide analogs having increased oral bioavarilability
|
|
JP2001504448A
(ja)
|
1996-08-30 |
2001-04-03 |
フュルステ，イェンス，ペーター |
核酸の鏡面対称選択および進化
|
|
EP1006798A4
(en)
|
1996-09-05 |
2003-03-05 |
Massachusetts Inst Technology |
COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISORDERS AND NEURODEGENERATIVE DISEASES
|
|
KR100518903B1
(ko)
|
1996-10-25 |
2005-10-06 |
미네소타 마이닝 앤드 매뉴팩춰링 캄파니 |
Ｔｈ2 매개 질병 및 관련 질병의 치료용 면역 반응 조절 화합물
|
|
US6042820A
(en)
|
1996-12-20 |
2000-03-28 |
Connaught Laboratories Limited |
Biodegradable copolymer containing α-hydroxy acid and α-amino acid units
|
|
US6127533A
(en)
|
1997-02-14 |
2000-10-03 |
Isis Pharmaceuticals, Inc. |
2'-O-aminooxy-modified oligonucleotides
|
|
WO1998037919A1
(en)
|
1997-02-28 |
1998-09-03 |
University Of Iowa Research Foundation |
USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE IN THE TREATMENT OF LPS-ASSOCIATED DISORDERS
|
|
AU753688B2
(en)
|
1997-03-10 |
2002-10-24 |
Ottawa Civic Loeb Research Institute |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
|
US5989591A
(en)
|
1997-03-14 |
1999-11-23 |
American Home Products Corporation |
Rapamycin formulations for oral administration
|
|
US6211159B1
(en)
|
1997-04-11 |
2001-04-03 |
University Of Toronto |
Flagellin gene, FlaC of campylobacter
|
|
US6060082A
(en)
|
1997-04-18 |
2000-05-09 |
Massachusetts Institute Of Technology |
Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
|
|
AU7690898A
(en)
|
1997-05-20 |
1998-12-11 |
Ottawa Civic Hospital Loeb Research Institute |
Vectors and methods for immunization or therapeutic protocols
|
|
US5985325A
(en)
|
1997-06-13 |
1999-11-16 |
American Home Products Corporation |
Rapamycin formulations for oral administration
|
|
US5837752A
(en)
|
1997-07-17 |
1998-11-17 |
Massachusetts Institute Of Technology |
Semi-interpenetrating polymer networks
|
|
US6989435B2
(en)
|
1997-09-11 |
2006-01-24 |
Cambridge University Technical Services Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
|
DE19745950A1
(de)
|
1997-10-17 |
1999-04-22 |
Dds Drug Delivery Service Ges |
Arzneistoffträgerpartikel für die gewebespezifische Arzneistoffapplikation
|
|
NZ504800A
(en)
|
1997-11-28 |
2001-10-26 |
Sumitomo Pharma |
6-Amino-9-benzyl-8-hydroxy-purine derivatives and interferon inducers, antiviral agents, anticancer agents and therapeutic agents for immunologic diseases thereof
|
|
US6254890B1
(en)
|
1997-12-12 |
2001-07-03 |
Massachusetts Institute Of Technology |
Sub-100nm biodegradable polymer spheres capable of transporting and releasing nucleic acids
|
|
US6197229B1
(en)
|
1997-12-12 |
2001-03-06 |
Massachusetts Institute Of Technology |
Method for high supercoiled DNA content microspheres
|
|
US6506559B1
(en)
|
1997-12-23 |
2003-01-14 |
Carnegie Institute Of Washington |
Genetic inhibition by double-stranded RNA
|
|
FR2775435B1
(fr)
|
1998-02-27 |
2000-05-26 |
Bioalliance Pharma |
Nanoparticules comprenant au moins un polymere et au moins un compose apte a complexer un ou plusieurs principes actifs
|
|
WO1999045957A2
(en)
*
|
1998-03-09 |
1999-09-16 |
Smithkline Beecham Biologicals S.A. |
Combined vaccine compositions
|
|
US6232287B1
(en)
|
1998-03-13 |
2001-05-15 |
The Burnham Institute |
Molecules that home to various selected organs or tissues
|
|
US6506577B1
(en)
|
1998-03-19 |
2003-01-14 |
The Regents Of The University Of California |
Synthesis and crosslinking of catechol containing copolypeptides
|
|
US6686446B2
(en)
|
1998-03-19 |
2004-02-03 |
The Regents Of The University Of California |
Methods and compositions for controlled polypeptide synthesis
|
|
US6632922B1
(en)
|
1998-03-19 |
2003-10-14 |
The Regents Of The University Of California |
Methods and compositions for controlled polypeptide synthesis
|
|
ATE356630T1
(de)
|
1998-04-03 |
2007-04-15 |
Univ Iowa Res Found |
Verfahren und produkte zur stimulierung des immunsystems mittels immunotherapeutischer oligonukleotide und zytokine
|
|
EP1077708A1
(en)
|
1998-05-06 |
2001-02-28 |
University Of Iowa Research Foundation |
Methods for the prevention and treatment of parasitic infections and related diseases using cpg oligonucleotides
|
|
SE9801923D0
(sv)
|
1998-05-29 |
1998-05-29 |
Independent Pharmaceutical Ab |
Nicotine vaccine
|
|
US6693086B1
(en)
|
1998-06-25 |
2004-02-17 |
National Jewish Medical And Research Center |
Systemic immune activation method using nucleic acid-lipid complexes
|
|
US6242589B1
(en)
|
1998-07-14 |
2001-06-05 |
Isis Pharmaceuticals, Inc. |
Phosphorothioate oligonucleotides having modified internucleoside linkages
|
|
AU763975B2
(en)
|
1998-07-29 |
2003-08-07 |
Novartis Vaccines And Diagnostics, Inc. |
Microparticles with adsorbent surfaces, methods of making same, and uses thereof
|
|
DE19839214C1
(de)
|
1998-08-28 |
2000-05-25 |
Aventis Res & Tech Gmbh & Co |
Verfahren zur Herstellung von sphärischen Mikropartikeln mit glatter Oberfläche, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen, sowie mit diesem Verfahren erhältliche Mikropartikel und deren Verwendung
|
|
IL141868A0
(en)
|
1998-10-05 |
2002-03-10 |
M & E Biotech As |
Novel methods for therapeutic vaccination
|
|
US6306640B1
(en)
|
1998-10-05 |
2001-10-23 |
Genzyme Corporation |
Melanoma antigenic peptides
|
|
DE69935606T9
(de)
|
1998-10-16 |
2021-03-11 |
Glaxosmithkline Biologicals S.A. |
Adjuvanzsysteme und impfstoffe
|
|
EP1126826B3
(en)
|
1998-11-02 |
2019-05-15 |
Alkermes Pharma Ireland Limited |
Multiparticulate modified release composition of methylphenidate
|
|
US7521068B2
(en)
|
1998-11-12 |
2009-04-21 |
Elan Pharma International Ltd. |
Dry powder aerosols of nanoparticulate drugs
|
|
US6232082B1
(en)
|
1998-12-01 |
2001-05-15 |
Nabi |
Hapten-carrier conjugates for treating and preventing nicotine addiction
|
|
US6486168B1
(en)
|
1999-01-08 |
2002-11-26 |
3M Innovative Properties Company |
Formulations and methods for treatment of mucosal associated conditions with an immune response modifier
|
|
US6403779B1
(en)
|
1999-01-08 |
2002-06-11 |
Isis Pharmaceuticals, Inc. |
Regioselective synthesis of 2′-O-modified nucleosides
|
|
TR200101943T2
(tr)
|
1999-01-08 |
2002-04-22 |
3M Innovative Properties Company |
Bir immun cevap modifayeri ile mukoza ile ilgili durumların tedavisine yönelik formülasyonlar ve metodlar.
|
|
US7238711B1
(en)
|
1999-03-17 |
2007-07-03 |
Cambridge University Technical Services Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
|
DE19956568A1
(de)
|
1999-01-30 |
2000-08-17 |
Roland Kreutzer |
Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
|
|
US6444192B1
(en)
|
1999-02-05 |
2002-09-03 |
The Regents Of The University Of California |
Diagnostic imaging of lymph structures
|
|
US6558951B1
(en)
|
1999-02-11 |
2003-05-06 |
3M Innovative Properties Company |
Maturation of dendritic cells with immune response modifying compounds
|
|
US6248363B1
(en)
|
1999-11-23 |
2001-06-19 |
Lipocine, Inc. |
Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
|
|
JP4812942B2
(ja)
|
1999-02-26 |
2011-11-09 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル |
ＣＧモチーフを含むオリゴヌクレオチドを用いるＮｅｉｓｓｅｒｉａ抗原殺菌活性の増強
|
|
US6110462A
(en)
|
1999-03-03 |
2000-08-29 |
The Scripps Research Institute |
Enzymatic DNA molecules that contain modified nucleotides
|
|
DE60014076T2
(de)
|
1999-04-19 |
2005-10-13 |
Glaxosmithkline Biologicals S.A. |
Adjuvans-zusammensetzung, enthaltend saponin und ein immunstimulatorisches oligonukleotid
|
|
US7390780B2
(en)
|
1999-04-23 |
2008-06-24 |
Alza Corporation |
Gene delivery mediated by liposome-DNA complex with cleavable peg surface modification
|
|
US6800296B1
(en)
|
1999-05-19 |
2004-10-05 |
Massachusetts Institute Of Technology |
Modification of surfaces using biological recognition events
|
|
US6331539B1
(en)
|
1999-06-10 |
2001-12-18 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
|
US6815170B1
(en)
|
1999-06-30 |
2004-11-09 |
John Wayne Cancer Institute |
Methods for lymph node identification
|
|
AU6635900A
(en)
|
1999-08-13 |
2001-03-13 |
Point Biomedical Corporation |
Microparticles useful as ultrasonic contrast agents and for lymphatic system
|
|
SK287400B6
(sk)
|
1999-09-25 |
2010-08-09 |
University Of Iowa Research Foundation |
Prostriedok s obsahom imunostimulačnej nukleovej kyseliny a jeho použitie na stimuláciu imunitnej reakcie
|
|
JP2003511421A
(ja)
|
1999-10-12 |
2003-03-25 |
ナショナル リサーチ カウンシル オブ カナダ |
細胞毒性ｔリンパ球（ｃｔｌ）応答を誘発し、そして細胞内病原体及び癌に対してワクチン接種された宿主を保護するための無細胞ワクチンのための免疫調節キャリヤーとしてのアルキオソーム
|
|
CA2391534A1
(en)
|
1999-11-15 |
2001-05-25 |
Drug Innovation & Design, Inc. |
Selective cellular targeting: multifunctional delivery vehicles
|
|
US7223398B1
(en)
|
1999-11-15 |
2007-05-29 |
Dynavax Technologies Corporation |
Immunomodulatory compositions containing an immunostimulatory sequence linked to antigen and methods of use thereof
|
|
AU774593C
(en)
|
2000-01-13 |
2005-06-23 |
Nanosphere, Inc. |
Nanoparticles having oligonucleotides attached thereto and uses therefor
|
|
AT409085B
(de)
|
2000-01-28 |
2002-05-27 |
Cistem Biotechnologies Gmbh |
Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen
|
|
US20050032733A1
(en)
|
2001-05-18 |
2005-02-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SiNA)
|
|
US20050020525A1
(en)
|
2002-02-20 |
2005-01-27 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
US8202979B2
(en)
|
2002-02-20 |
2012-06-19 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
|
|
JP4751556B2
(ja)
|
2000-02-28 |
2011-08-17 |
ジーンシーグス， インコーポレイテッド |
ナノカプセルカプセル化システムおよび方法
|
|
US7129222B2
(en)
|
2000-03-10 |
2006-10-31 |
Dynavax Technologies Corporation |
Immunomodulatory formulations and methods for use thereof
|
|
US7157437B2
(en)
|
2000-03-10 |
2007-01-02 |
Dynavax Technologies Corporation |
Methods of ameliorating symptoms of herpes infection using immunomodulatory polynucleotide sequences
|
|
US20030129251A1
(en)
|
2000-03-10 |
2003-07-10 |
Gary Van Nest |
Biodegradable immunomodulatory formulations and methods for use thereof
|
|
SE0000933D0
(sv)
|
2000-03-21 |
2000-03-21 |
Independent Pharmaceutica Ab |
Method of producing 6-substituted (S)-nicotine derivatives and intermediate compounds
|
|
PT1309726E
(pt)
|
2000-03-30 |
2010-03-08 |
Whitehead Biomedical Inst |
Mediadores de interferência por rna específicos de sequência de rna
|
|
CA2407897A1
(en)
|
2000-05-05 |
2001-11-15 |
Cytos Biotechnology Ag |
Molecular antigen arrays and vaccines
|
|
US7192725B2
(en)
|
2000-05-19 |
2007-03-20 |
University Of Toronto |
Flagellin gene, flaC of Campylobacter
|
|
US6610713B2
(en)
|
2000-05-23 |
2003-08-26 |
North Shore - Long Island Jewish Research Institute |
Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
|
|
GB0108364D0
(en)
*
|
2001-04-03 |
2001-05-23 |
Glaxosmithkline Biolog Sa |
Vaccine composition
|
|
AU9475001A
(en)
|
2000-09-26 |
2002-04-08 |
Hybridon Inc |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
|
|
AU2001297913A1
(en)
*
|
2000-10-13 |
2002-12-23 |
Ligocyte Pharmaceuticals, Inc. |
Polyvalent nanoparticles
|
|
GB0025414D0
(en)
|
2000-10-16 |
2000-11-29 |
Consejo Superior Investigacion |
Nanoparticles
|
|
JP2004511527A
(ja)
|
2000-10-18 |
2004-04-15 |
グラクソスミスクライン バイオロジカルズ ソシエテ アノニム |
ワクチン
|
|
EP1355965B1
(en)
|
2000-10-19 |
2012-09-19 |
Ecole Polytechnique Fédérale de Lausanne (EPFL) |
Method of synthesizing block copolymers for multifunctional self-assembled systems
|
|
US7592008B2
(en)
|
2000-11-20 |
2009-09-22 |
The Board Of Trustees Of The University Of Illinois, A Body Corporate And Politic Of The State Of Illinois |
Membrane scaffold proteins
|
|
US20040259247A1
(en)
|
2000-12-01 |
2004-12-23 |
Thomas Tuschl |
Rna interference mediating small rna molecules
|
|
US20060142202A1
(en)
|
2000-12-08 |
2006-06-29 |
3M Innovative Properties Company |
Compositions and methods for targeted delivery of immune response modifiers
|
|
JP4188687B2
(ja)
|
2000-12-27 |
2008-11-26 |
ダイナバックス テクノロジーズ コーポレイション |
免疫変調ポリヌクレオチド及びその使用法
|
|
US7097837B2
(en)
|
2001-02-19 |
2006-08-29 |
Pharmexa A/S |
Synthetic vaccine agents
|
|
US20030175950A1
(en)
|
2001-05-29 |
2003-09-18 |
Mcswiggen James A. |
RNA interference mediated inhibition of HIV gene expression using short interfering RNA
|
|
WO2004030608A2
(en)
|
2001-06-05 |
2004-04-15 |
The Regents Of The University Of Michigan |
Nanoemulsion vaccines
|
|
DE60140863D1
(de)
|
2001-06-10 |
2010-02-04 |
Noxxon Pharma Ag |
Verwendung von L-Polynukleotiden zur diagnostischen Bilderzeugung
|
|
EP2241309A3
(en)
|
2001-07-10 |
2012-12-26 |
Corixa Corporation |
Methods for encapsulation of proteins and adjuants in microspheres
|
|
JP4607452B2
(ja)
|
2001-08-07 |
2011-01-05 |
ダイナバックス テクノロジーズ コーポレイション |
免疫調節性組成物、製剤およびその使用方法
|
|
US6818732B2
(en)
|
2001-08-30 |
2004-11-16 |
The Regents Of The University Of California |
Transition metal initiators for controlled poly (beta-peptide) synthesis from beta-lactam monomers
|
|
US20030054042A1
(en)
|
2001-09-14 |
2003-03-20 |
Elaine Liversidge |
Stabilization of chemical compounds using nanoparticulate formulations
|
|
US7276489B2
(en)
|
2002-10-24 |
2007-10-02 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends
|
|
CA2465405A1
(en)
|
2001-11-02 |
2003-05-08 |
Wockhardt Limited |
Controlled release compositions for macrolide antimicrobial agents
|
|
US8088388B2
(en)
|
2002-02-14 |
2012-01-03 |
United Biomedical, Inc. |
Stabilized synthetic immunogen delivery system
|
|
EP2572707A3
(en)
|
2002-02-20 |
2013-11-06 |
Novartis Vaccines and Diagnostics, Inc. |
Microparticles with adsorbed polypeptide-containing molecules
|
|
US20030232013A1
(en)
|
2002-02-22 |
2003-12-18 |
Gary Sieckman |
Therapeutic and diagnostic targeting of cancers cells with tumor homing peptides
|
|
US8153141B2
(en)
|
2002-04-04 |
2012-04-10 |
Coley Pharmaceutical Gmbh |
Immunostimulatory G, U-containing oligoribonucleotides
|
|
US20040038303A1
(en)
|
2002-04-08 |
2004-02-26 |
Unger Gretchen M. |
Biologic modulations with nanoparticles
|
|
US7285289B2
(en)
|
2002-04-12 |
2007-10-23 |
Nagy Jon O |
Nanoparticle vaccines
|
|
US20080233181A1
(en)
|
2002-04-12 |
2008-09-25 |
Nagy Jon O |
Nanoparticle adjuvants for sub-unit vaccines
|
|
US7524630B2
(en)
|
2002-04-22 |
2009-04-28 |
University Of Florida Research Foundation, Inc. |
Functionalized nanoparticles and methods of use
|
|
US6824338B2
(en)
*
|
2002-05-28 |
2004-11-30 |
Satco, Inc. |
Air transport modular container system
|
|
AU2003276131A1
(en)
|
2002-06-18 |
2003-12-31 |
Epigenesis Pharmaceuticals, Inc. |
A dry powder oligonucleotide formulation, preparation and its uses
|
|
AU2003269904A1
(en)
|
2002-07-10 |
2004-01-23 |
The Ohio State University Research Foundation |
Antigen-polymer compositions
|
|
NZ537003A
(en)
|
2002-07-18 |
2008-03-28 |
Cytos Biotechnology Ag |
Hapten-carrier conjugates comprising virus like particles and uses thereof
|
|
NZ538812A
(en)
|
2002-08-15 |
2009-02-28 |
3M Innovative Properties Co |
Immunostimulatory compositions and methods of stimulating an immune response
|
|
US20040091503A1
(en)
*
|
2002-08-20 |
2004-05-13 |
Genitrix, Llc |
Lectin compositions and methods for modulating an immune response to an antigen
|
|
US7488792B2
(en)
|
2002-08-28 |
2009-02-10 |
Burnham Institute For Medical Research |
Collagen-binding molecules that selectively home to tumor vasculature and methods of using same
|
|
WO2004022594A2
(en)
|
2002-09-06 |
2004-03-18 |
Cytos Biotechnology Ag |
Immune modulatory compounds and methods
|
|
AU2003302226A1
(en)
|
2002-09-24 |
2004-06-30 |
University Of Kentucky Research Foundation |
Nanoparticle-based vaccine delivery system containing adjuvant
|
|
US7008411B1
(en)
|
2002-09-30 |
2006-03-07 |
Advanced Cardiovascular Systems, Inc. |
Method and apparatus for treating vulnerable plaque
|
|
NO20024755D0
(no)
|
2002-10-03 |
2002-10-03 |
Amersham Health As |
Metode
|
|
US7670627B2
(en)
|
2002-12-09 |
2010-03-02 |
Salvona Ip Llc |
pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients
|
|
EP1578954A4
(en)
|
2002-12-11 |
2010-08-11 |
Coley Pharm Group Inc |
5'-CPG NUCLEIC ACIDS AND USE METHOD
|
|
SE0203687D0
(sv)
|
2002-12-13 |
2002-12-13 |
Ian Harwigsson Med Adagit Fa |
Pharmaceutical Porous Particles
|
|
PT1992635E
(pt)
|
2002-12-23 |
2012-03-20 |
Dynavax Tech Corp |
Oligonucleótidos de sequência imunoestimuladora e métodos de utilização dos mesmos
|
|
AU2003300184B8
(en)
|
2002-12-30 |
2009-12-03 |
3M Innovative Properties Company |
Immunostimulatory combinations
|
|
US20040156846A1
(en)
|
2003-02-06 |
2004-08-12 |
Triton Biosystems, Inc. |
Therapy via targeted delivery of nanoscale particles using L6 antibodies
|
|
JP2006517974A
(ja)
|
2003-02-13 |
2006-08-03 |
スリーエム イノベイティブ プロパティズ カンパニー |
Ｉｒｍ化合物およびトル様受容体８に関する方法および組成物
|
|
WO2004071493A1
(en)
|
2003-02-17 |
2004-08-26 |
Peter Burkhard |
Peptidic nanoparticles as drug delivery and antigen display systems
|
|
KR20060015482A
(ko)
*
|
2003-03-21 |
2006-02-17 |
와이어쓰 |
인터루킨-21/인터루킨-21 수용체의 작용제를 이용한면역장애의 치료
|
|
US20040191215A1
(en)
|
2003-03-25 |
2004-09-30 |
Michael Froix |
Compositions for induction of a therapeutic response
|
|
EP1605972A2
(en)
|
2003-03-26 |
2005-12-21 |
Cytos Biotechnology AG |
Hiv-peptide-carrier-conjugates
|
|
EP1594482A1
(en)
|
2003-03-26 |
2005-11-16 |
LTT Bio-Pharma Co., Ltd. |
Intravenous nanoparticles for targeting drug delivery and sustained drug release
|
|
AU2004244962A1
(en)
|
2003-04-10 |
2004-12-16 |
3M Innovative Properties Company |
Delivery of immune response modifier compounds using metal-containing particulate support materials
|
|
US7731967B2
(en)
*
|
2003-04-30 |
2010-06-08 |
Novartis Vaccines And Diagnostics, Inc. |
Compositions for inducing immune responses
|
|
EP1631264B8
(en)
*
|
2003-06-02 |
2017-05-24 |
GlaxoSmithKline Biologicals SA |
Immunogenic compositions based on microparticles comprising adsorbed toxoid and a polysaccharide-containing antigen
|
|
US7727969B2
(en)
|
2003-06-06 |
2010-06-01 |
Massachusetts Institute Of Technology |
Controlled release nanoparticle having bound oligonucleotide for targeted delivery
|
|
US7149574B2
(en)
|
2003-06-09 |
2006-12-12 |
Palo Alto Investors |
Treatment of conditions through electrical modulation of the autonomic nervous system
|
|
CA2544240A1
(en)
|
2003-07-22 |
2005-02-17 |
Cytos Biotechnology Ag |
Cpg-packaged liposomes
|
|
US20050042298A1
(en)
|
2003-08-20 |
2005-02-24 |
Pardridge William M. |
Immunonanoparticles
|
|
AU2004281634B2
(en)
*
|
2003-09-03 |
2011-01-27 |
Dendritherapeutics, Inc. |
Multiplex vaccines
|
|
US7943179B2
(en)
|
2003-09-23 |
2011-05-17 |
Massachusetts Institute Of Technology |
pH triggerable polymeric particles
|
|
US7771726B2
(en)
|
2003-10-08 |
2010-08-10 |
New York University |
Use of synthetic glycolipids as universal adjuvants for vaccines against cancer and infectious diseases
|
|
US20080160089A1
(en)
*
|
2003-10-14 |
2008-07-03 |
Medivas, Llc |
Vaccine delivery compositions and methods of use
|
|
US7829119B2
(en)
|
2003-10-20 |
2010-11-09 |
William Marsh Rice University |
Method to fabricate microcapsules from polymers and charged nanoparticles
|
|
CN1608675A
(zh)
*
|
2003-10-22 |
2005-04-27 |
四川大学 |
一种新型高分子材料载药纳米粒及制法和用途
|
|
GEP20094767B
(en)
|
2003-10-30 |
2009-09-10 |
Coley Pharm Group Inc |
C-class oligonucleotide analogs with enhanced immunostimulatory potency
|
|
CN1544638A
(zh)
*
|
2003-11-28 |
2004-11-10 |
中国药科大学 |
可载荷多肽的病毒样颗粒
|
|
WO2005055949A2
(en)
|
2003-12-09 |
2005-06-23 |
The Children's Hospital Of Philadelphia |
Sustained release preparations composed of biocompatible complex microparticles
|
|
KR100581967B1
(ko)
|
2003-12-18 |
2006-05-22 |
한국유나이티드제약 주식회사 |
소화성 궤양 치료를 위한 프로톤펌프 저해제와클래리스로마이신을 함유하는 이중 펠렛 제제 및 그의제조방법
|
|
FR2863890B1
(fr)
*
|
2003-12-19 |
2006-03-24 |
Aventis Pasteur |
Composition immunostimulante
|
|
DK1704585T3
(en)
|
2003-12-19 |
2017-05-22 |
Univ North Carolina Chapel Hill |
Methods for preparing isolated micro- and nanostructures using soft lithography or printing lithography
|
|
US9040090B2
(en)
|
2003-12-19 |
2015-05-26 |
The University Of North Carolina At Chapel Hill |
Isolated and fixed micro and nano structures and methods thereof
|
|
EP1550458A1
(en)
*
|
2003-12-23 |
2005-07-06 |
Vectron Therapeutics AG |
Synergistic liposomal adjuvants
|
|
WO2005065418A2
(en)
|
2003-12-31 |
2005-07-21 |
Board Of Regents, The University Of Texas System |
Compositions and methods of use of targeting peptides for diagnosis and therapy
|
|
US20070087986A1
(en)
|
2004-01-26 |
2007-04-19 |
Brett Premack |
Compositions and methods for enhancing immunity by chemoattractant adjuvants
|
|
WO2005097993A2
(en)
|
2004-02-19 |
2005-10-20 |
Coley Pharmaceutical Group, Inc. |
Immunostimulatory viral rna oligonucleotides
|
|
EP1735010A4
(en)
|
2004-04-09 |
2008-08-27 |
3M Innovative Properties Co |
METHODS, COMPOSITIONS AND PREPARATIONS FOR ADMINISTRATION OF IMMUNE RESPONSE MODIFIERS (MRI)
|
|
AU2005325262B2
(en)
|
2004-04-27 |
2011-08-11 |
Alnylam Pharmaceuticals, Inc. |
Single-stranded and double-stranded oligonucleotides comprising a 2-arylpropyl moiety
|
|
ES2246695B1
(es)
|
2004-04-29 |
2007-05-01 |
Instituto Cientifico Y Tecnologico De Navarra, S.A. |
Composicion estimuladora de la respuesta inmunitaria que comprende nanoparticulas a base de un copolimero de metil vinil eter y anhidrido maleico.
|
|
ES2389080T3
(es)
|
2004-06-11 |
2012-10-23 |
Riken |
Fármaco que presenta un ligando de células reguladoras contenido en el liposoma
|
|
GB0413868D0
(en)
*
|
2004-06-21 |
2004-07-21 |
Chiron Srl |
Dimensional anlaysis of saccharide conjugates
|
|
JP2008512350A
(ja)
|
2004-07-01 |
2008-04-24 |
イェール ユニバーシティ |
標的化され、そして高密度で薬物が負荷されるポリマー性物質
|
|
US20080206270A1
(en)
|
2004-07-08 |
2008-08-28 |
Minev Boris R |
Enhancing Class I Antigen Presentation With Synthetic Sequences
|
|
US8017151B2
(en)
|
2004-09-07 |
2011-09-13 |
Board Of Regents Of The University Of Nebraska By And Behalf Of The University Of Nebraska Medical Center |
Amphiphilic polymer-protein conjugates and methods of use thereof
|
|
US20080213308A1
(en)
|
2004-09-14 |
2008-09-04 |
Nicholas Valiante |
Imidazoquinoline Compounds
|
|
CN1692943A
(zh)
|
2004-09-17 |
2005-11-09 |
四川大学 |
CpG DNA分子抗感染免疫制剂的制备和应用
|
|
US9079765B2
(en)
|
2004-10-01 |
2015-07-14 |
Midatech Ltd. |
Nanoparticles comprising antigens and adjuvants, and immunogenic structures
|
|
AU2005294214A1
(en)
|
2004-10-07 |
2006-04-20 |
Emory University |
Multifunctional nanoparticles conjugates and their use
|
|
MY159370A
(en)
|
2004-10-20 |
2016-12-30 |
Coley Pharm Group Inc |
Semi-soft-class immunostimulatory oligonucleotides
|
|
US9492400B2
(en)
|
2004-11-04 |
2016-11-15 |
Massachusetts Institute Of Technology |
Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
|
|
US9789171B2
(en)
|
2004-11-05 |
2017-10-17 |
The General Hospital Corporation |
Anti-fugetactic agents for the treatment of ovarian cancer
|
|
ES2434029T3
(es)
|
2004-11-15 |
2013-12-13 |
Novartis Vaccines And Diagnostics, Inc. |
Composiciones inmunogénicas que contiene antígeno de antrax, micropartículas de polímero biodegradable, y adyuvante inmunológico que contiene polinucleótido
|
|
US20060111271A1
(en)
|
2004-11-24 |
2006-05-25 |
Cerny Erich H |
Active and passive immunization against pharmacologically active hapten molecules using a synthetic carrier compound composed of similar elements
|
|
US20070292386A9
(en)
*
|
2004-12-02 |
2007-12-20 |
Campbell Robert L |
Vaccine formulations for intradermal delivery comprising adjuvants and antigenic agents
|
|
WO2006066158A2
(en)
|
2004-12-14 |
2006-06-22 |
Alnylam Pharmaceuticals, Inc. |
Rnai modulation of mll-af4 and uses thereof
|
|
US20060257359A1
(en)
|
2005-02-28 |
2006-11-16 |
Cedric Francois |
Modifying macrophage phenotype for treatment of disease
|
|
CA2602946A1
(en)
|
2005-03-22 |
2006-09-28 |
Medstar Health, Inc. |
Delivery systems and methods for diagnosing and treating cardiovascular diseases
|
|
US7709001B2
(en)
|
2005-04-08 |
2010-05-04 |
Wyeth Llc |
Multivalent pneumococcal polysaccharide-protein conjugate composition
|
|
US20080305161A1
(en)
|
2005-04-13 |
2008-12-11 |
Pfizer Inc |
Injectable depot formulations and methods for providing sustained release of nanoparticle compositions
|
|
WO2006116458A2
(en)
|
2005-04-26 |
2006-11-02 |
Coley Pharmaceutical Gmbh |
Modified oligoribonucleotide analogs with enhances immunostimulatory activity
|
|
EP1877069A2
(de)
|
2005-05-04 |
2008-01-16 |
Noxxon Pharma AG |
Neue verwendung von spiegelmeren
|
|
WO2006122223A2
(en)
|
2005-05-10 |
2006-11-16 |
Emory University |
Strategies for delivery of active agents using micelles and particles
|
|
EP1904553A4
(en)
|
2005-07-06 |
2013-04-24 |
Molly S Shoichet |
METHOD OF IMMOBILIZING BIOMOLECULE ON POLYMERS INVOLVING FAST TYPE CHEMICAL REACTIONS
|
|
CA2618807C
(en)
|
2005-08-12 |
2015-01-06 |
University Health Network |
Methods and devices for lymphatic targeting
|
|
TWI382019B
(zh)
|
2005-08-19 |
2013-01-11 |
Array Biopharma Inc |
作為類鐸受體（ｔｏｌｌ-ｌｉｋｅ ｒｅｃｅｐｔｏｒ）調節劑之胺基二氮雜呯
|
|
TWI404537B
(zh)
|
2005-08-19 |
2013-08-11 |
Array Biopharma Inc |
作為類鐸受體（ｔｏｌｌ-ｌｉｋｅ ｒｅｃｅｐｔｏｒ）調節劑之８-經取代苯并氮雜呯
|
|
ES2577514T3
(es)
|
2005-08-22 |
2016-07-15 |
The Regents Of The University Of California |
Antagonistas de TLR
|
|
JP2009507049A
(ja)
|
2005-09-09 |
2009-02-19 |
北京徳科瑞医薬科技有限公司 |
リン脂質のポリエチレングリコール誘導体に包み込まれたビンカアルカロイド系制癌剤のナノミセル製剤
|
|
PL1957647T3
(pl)
|
2005-11-25 |
2015-07-31 |
Zoetis Belgium S A |
Oligorybonukleotydy immunostymulujące
|
|
EP1963308A4
(en)
|
2005-11-28 |
2010-12-15 |
Nabi Biopharmaceuticals |
METHOD FOR PRODUCING A NICOTINE HAPTEN
|
|
WO2008051245A2
(en)
|
2005-12-02 |
2008-05-02 |
Novartis Ag |
Nanoparticles for use in immunogenic compositions
|
|
EP1973608A1
(en)
|
2005-12-14 |
2008-10-01 |
Cytos Biotechnology AG |
Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity
|
|
US9267937B2
(en)
|
2005-12-15 |
2016-02-23 |
Massachusetts Institute Of Technology |
System for screening particles
|
|
US7842312B2
(en)
|
2005-12-29 |
2010-11-30 |
Cordis Corporation |
Polymeric compositions comprising therapeutic agents in crystalline phases, and methods of forming the same
|
|
CN101410098B
(zh)
|
2006-01-23 |
2012-01-18 |
耶路撒冷希伯来大学伊森姆研究发展公司 |
包括含亲脂性药物的纳米胶囊的微球
|
|
JP2009525341A
(ja)
|
2006-01-31 |
2009-07-09 |
メディバス エルエルシー |
ワクチン送達組成物および使用法
|
|
US8007831B2
(en)
|
2006-02-10 |
2011-08-30 |
Biocompatibles Uk Limited |
Loading of hydrophobic drugs into hydrophilic polymer delivery systems
|
|
US8021689B2
(en)
|
2006-02-21 |
2011-09-20 |
Ecole Polytechnique Federale de Lausanne (“EPFL”) |
Nanoparticles for immunotherapy
|
|
WO2007100699A2
(en)
|
2006-02-24 |
2007-09-07 |
Novartis Ag |
Microparticles containing biodegradable polymer and cationic polysaccharide for use in immunogenic compositions
|
|
WO2007109810A2
(en)
|
2006-03-23 |
2007-09-27 |
Novartis Ag |
Methods for the preparation of imidazole-containing compounds
|
|
ES2776100T3
(es)
|
2006-03-31 |
2020-07-29 |
Massachusetts Inst Technology |
Sistema para el suministro dirigido de agentes terapéuticos
|
|
US20100247653A1
(en)
|
2006-04-11 |
2010-09-30 |
Hans Lautenschlager |
Nanoparticles containing nicotine and/or cotinine, dispersions, and use thereof
|
|
US8367113B2
(en)
|
2006-05-15 |
2013-02-05 |
Massachusetts Institute Of Technology |
Polymers for functional particles
|
|
US20110052697A1
(en)
|
2006-05-17 |
2011-03-03 |
Gwangju Institute Of Science & Technology |
Aptamer-Directed Drug Delivery
|
|
MX2008015529A
(es)
|
2006-06-12 |
2009-01-13 |
Cytos Biotechnology Ag |
Procesos para empacar oligonucleotidos en particulas similares a virus de bacteriofagos de arn.
|
|
JP2010502766A
(ja)
|
2006-06-16 |
2010-01-28 |
フロリダ アトランティック ユニヴァーシティ |
アジュバントとしてのキチン微粒子
|
|
US20100028381A1
(en)
|
2006-06-19 |
2010-02-04 |
3M Innovative Properties Company |
Formulation for delivery of immune response modifiers
|
|
WO2007150030A2
(en)
|
2006-06-23 |
2007-12-27 |
Massachusetts Institute Of Technology |
Microfluidic synthesis of organic nanoparticles
|
|
WO2008002568A2
(en)
|
2006-06-26 |
2008-01-03 |
Mutual Pharmaceutical Company, Inc. |
Active agent formulations, methods of making, and methods of use
|
|
US20100144845A1
(en)
|
2006-08-04 |
2010-06-10 |
Massachusetts Institute Of Technology |
Oligonucleotide systems for targeted intracellular delivery
|
|
US20080171059A1
(en)
|
2006-08-07 |
2008-07-17 |
Shanshan Wu Howland |
Methods and compositions for increased priming of t-cells through cross-presentation of exogenous antigens
|
|
MX2009001533A
(es)
|
2006-08-11 |
2009-02-18 |
Panacea Biotec Ltd |
Particulas para el suministro de ingredientes activos, procedimiento de elaboracion y sus composiciones.
|
|
US8945582B2
(en)
*
|
2006-09-07 |
2015-02-03 |
Glaxosmithkline Biologicals S.A. |
Vaccine
|
|
WO2008033432A2
(en)
|
2006-09-12 |
2008-03-20 |
Coley Pharmaceutical Group, Inc. |
Immune modulation by chemically modified ribonucleosides and oligoribonucleotides
|
|
CA2665090A1
(en)
|
2006-09-22 |
2008-03-27 |
Dana-Farber Cancer Institute, Inc. |
Methods for treating mica-related disorders
|
|
JP2010505883A
(ja)
|
2006-10-12 |
2010-02-25 |
ザ ユニバーシティー オブ クイーンズランド |
免疫応答を調節するための組成物および方法
|
|
WO2008147456A2
(en)
|
2006-11-20 |
2008-12-04 |
Massachusetts Institute Of Technology |
Drug delivery systems using fc fragments
|
|
SG177141A1
(en)
*
|
2006-12-06 |
2012-01-30 |
Novartis Ag |
Vaccines including antigen from four strains of influenza virus
|
|
EP2099496A2
(en)
|
2006-12-08 |
2009-09-16 |
Massachusetts Institute of Technology |
Delivery of nanoparticles and/or agents to cells
|
|
EP1932516A1
(en)
|
2006-12-11 |
2008-06-18 |
Universiteit Utrecht Holding B.V. |
Anti-inflammatory compounds containing compositions for treatment of cancer
|
|
WO2008071774A1
(en)
|
2006-12-14 |
2008-06-19 |
Cytos Biotechnology Ag |
Purification process for coat protein of rna bacteriophages
|
|
US20080149123A1
(en)
|
2006-12-22 |
2008-06-26 |
Mckay William D |
Particulate material dispensing hairbrush with combination bristles
|
|
ES2607901T3
(es)
|
2007-01-31 |
2017-04-04 |
Chongxi Yu |
Profármacos hidrosolubles cargados positivamente de 1H-imidazo[4,5-c]quinolin-4-aminas y compuestos relacionados con ratas de penetración de piel muy altas
|
|
ES2552471T3
(es)
|
2007-02-07 |
2015-11-30 |
The Regents Of The University Of California |
Conjugados de agonistas de TLR sintéticos y usos de los mismos
|
|
US9217129B2
(en)
|
2007-02-09 |
2015-12-22 |
Massachusetts Institute Of Technology |
Oscillating cell culture bioreactor
|
|
US8889117B2
(en)
|
2007-02-15 |
2014-11-18 |
Yale University |
Modular nanoparticles for adaptable vaccines
|
|
AU2008222678B2
(en)
|
2007-03-07 |
2013-01-17 |
The General Hospital Corporation |
Compositions and methods for the prevention and treatment of autoimmune conditions
|
|
US20100151031A1
(en)
|
2007-03-23 |
2010-06-17 |
Desimone Joseph M |
Discrete size and shape specific organic nanoparticles designed to elicit an immune response
|
|
US11246831B2
(en)
|
2007-03-30 |
2022-02-15 |
Particle Sciences, Inc. |
Particle formulations and uses thereof
|
|
WO2008124632A1
(en)
|
2007-04-04 |
2008-10-16 |
Massachusetts Institute Of Technology |
Amphiphilic compound assisted nanoparticles for targeted delivery
|
|
WO2008124634A1
(en)
|
2007-04-04 |
2008-10-16 |
Massachusetts Institute Of Technology |
Polymer-encapsulated reverse micelles
|
|
CA2683063A1
(en)
|
2007-04-09 |
2008-10-16 |
Chimeros, Inc. |
Self-assembling nanoparticle drug delivery system
|
|
JP2010523656A
(ja)
|
2007-04-12 |
2010-07-15 |
エモリー・ユニバーシティ |
ミセルおよび粒子を用いた、活性物質の送達のための新規の戦略
|
|
EP1982729A1
(en)
|
2007-04-20 |
2008-10-22 |
Cytos Biotechnology AG |
Vaccination Regimen for B-Cell Vaccines
|
|
US20080294089A1
(en)
*
|
2007-06-06 |
2008-11-27 |
Biovaluation & Analysis, Inc. |
Dendritic Polymers for Use in Acoustically Mediated Intracellular Drug Delivery in vivo
|
|
US20090047318A1
(en)
|
2007-08-16 |
2009-02-19 |
Abbott Cardiovascular Systems Inc. |
Nanoparticle-coated medical devices and formulations for treating vascular disease
|
|
US8394914B2
(en)
|
2007-08-24 |
2013-03-12 |
Board Of Trustees Of Michigan State University |
Functional polyglycolide nanoparticles derived from unimolecular micelles
|
|
WO2009027971A2
(en)
|
2007-08-27 |
2009-03-05 |
H2Q Water Industries Ltd. |
Antimicrobial polymers
|
|
US20090130210A1
(en)
|
2007-09-11 |
2009-05-21 |
Raheja Praveen |
Pharmaceutical compositions of sirolimus
|
|
WO2009079066A2
(en)
*
|
2007-09-26 |
2009-06-25 |
Aparna Biosciences |
Therapeutic and vaccine polyelectrolyte nanoparticle compositions
|
|
EP2630966B1
(en)
|
2007-10-12 |
2017-04-19 |
Massachusetts Institute of Technology |
Vaccine nanotechnology
|
|
WO2009069448A1
(ja)
|
2007-11-28 |
2009-06-04 |
Toray Industries, Inc. |
日本脳炎ワクチン用のアジュバント及び日本脳炎ワクチン
|
|
EP3067048B1
(en)
|
2007-12-07 |
2018-02-14 |
GlaxoSmithKline Biologicals SA |
Compositions for inducing immune responses
|
|
WO2009078754A1
(en)
|
2007-12-19 |
2009-06-25 |
Ardenia Investments, Ltd. |
Drug delivery system for administration of poorly water soluble pharmaceutically active substances
|
|
RU2540871C2
(ru)
*
|
2008-02-01 |
2015-02-10 |
Альфа-О Пептидес Аг |
Самоорганизующиеся пептидные наночастицы, полезные в качестве вакцин
|
|
EP2262489A2
(en)
|
2008-02-28 |
2010-12-22 |
Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts |
Hollow nanoparticles and uses thereof
|
|
WO2009111588A1
(en)
|
2008-03-04 |
2009-09-11 |
Liquidia Technologies, Inc. |
Immunomodulator particles and methods of treating
|
|
WO2009123480A1
(en)
|
2008-04-01 |
2009-10-08 |
Virionyx Corporation Ltd |
Anti-infective agents and uses thereof
|
|
US20090297621A1
(en)
|
2008-06-03 |
2009-12-03 |
Abbott Cardiovascular Systems Inc. |
Microparticles For The Treatment Of Disease
|
|
JP2012501965A
(ja)
|
2008-06-16 |
2012-01-26 |
バインド バイオサイエンシズ インコーポレイテッド |
薬剤を装填したポリマーナノ粒子及びその製造方法と使用方法
|
|
US8613951B2
(en)
|
2008-06-16 |
2013-12-24 |
Bind Therapeutics, Inc. |
Therapeutic polymeric nanoparticles with mTor inhibitors and methods of making and using same
|
|
MX379265B
(es)
|
2008-06-26 |
2025-03-11 |
Anterios Inc |
Aplicacion dérmica de toxina botulínica en nanoemulsiones para usarse en el tratamiento de trastornos de la piel.
|
|
WO2010003009A2
(en)
|
2008-07-01 |
2010-01-07 |
Emory University |
Synergistic induction of humoral and cellular immunity by combinatorial activation of toll-like receptors
|
|
CA2733147A1
(en)
|
2008-08-06 |
2010-02-11 |
Novartis Ag |
Microparticles for use in immunogenic compositions
|
|
EP2326646B1
(en)
|
2008-08-11 |
2013-07-31 |
GlaxoSmithKline LLC |
Purine derivatives for use in the treatment of allergic, inflammatory and infectious diseases
|
|
WO2010018132A1
(en)
|
2008-08-11 |
2010-02-18 |
Smithkline Beecham Corporation |
Compounds
|
|
UA103195C2
(uk)
|
2008-08-11 |
2013-09-25 |
Глаксосмитклайн Ллк |
Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань
|
|
JP2011530562A
(ja)
|
2008-08-11 |
2011-12-22 |
グラクソスミスクライン エルエルシー |
アレルギー性、炎症性及び感染性疾患治療用のプリン誘導体
|
|
US8323696B2
(en)
|
2008-08-29 |
2012-12-04 |
Ecole Polytechnique Federale De Lausanne |
Nanoparticles for immunotherapy
|
|
US8889635B2
(en)
|
2008-09-30 |
2014-11-18 |
The Regents Of The University Of Michigan |
Dendrimer conjugates
|
|
EP2172193A1
(en)
|
2008-10-02 |
2010-04-07 |
Capsulution Nanoscience AG |
Improved nanoparticulate compositions of poorly soluble compounds
|
|
WO2010037402A1
(en)
|
2008-10-02 |
2010-04-08 |
Dako Denmark A/S |
Molecular vaccines for infectious disease
|
|
US8343498B2
(en)
|
2008-10-12 |
2013-01-01 |
Massachusetts Institute Of Technology |
Adjuvant incorporation in immunonanotherapeutics
|
|
US8277812B2
(en)
*
|
2008-10-12 |
2012-10-02 |
Massachusetts Institute Of Technology |
Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
|
|
US8343497B2
(en)
*
|
2008-10-12 |
2013-01-01 |
The Brigham And Women's Hospital, Inc. |
Targeting of antigen presenting cells with immunonanotherapeutics
|
|
US8591905B2
(en)
*
|
2008-10-12 |
2013-11-26 |
The Brigham And Women's Hospital, Inc. |
Nicotine immunonanotherapeutics
|
|
US20100098770A1
(en)
|
2008-10-16 |
2010-04-22 |
Manikandan Ramalingam |
Sirolimus pharmaceutical formulations
|
|
WO2010047839A1
(en)
|
2008-10-25 |
2010-04-29 |
Aura Biosciences |
Modified plant virus particles and uses therefor
|
|
AU2009313392B2
(en)
|
2008-11-06 |
2016-05-05 |
Array Biopharma, Inc. |
Methods of synthesis of benzazepine derivatives
|
|
CN101822838B
(zh)
*
|
2009-03-05 |
2012-06-27 |
无锡纳奥生物医药有限公司 |
靶向识别肿瘤细胞的纳米药物载体材料及其制备和应用
|
|
US20100233231A1
(en)
|
2009-03-10 |
2010-09-16 |
Roger Labrecque |
Use of cryogenic processing to obtain a substantially-thickened formulation
|
|
US9764012B2
(en)
|
2009-04-01 |
2017-09-19 |
University Of Miami |
Vaccine compositions and methods of use thereof
|
|
KR20120022984A
(ko)
|
2009-04-21 |
2012-03-12 |
셀렉타 바이오사이언시즈, 인크. |
Ｔｈ１ 편향 반응을 제공하는 면역나노치료법
|
|
GB0908129D0
(en)
|
2009-05-12 |
2009-06-24 |
Innovata Ltd |
Composition
|
|
CA2762653A1
(en)
|
2009-05-27 |
2010-12-02 |
Selecta Biosciences, Inc. |
Immunomodulatory agent-polymeric compounds
|
|
CN102802624A
(zh)
|
2009-06-19 |
2012-11-28 |
太阳医药高级研发有限公司 |
药物的纳米分散体以及它的制备方法
|
|
EP2451485B1
(en)
|
2009-07-07 |
2016-03-02 |
The Research Foundation Of State University Of New York |
Lipidic compositions for induction of immune tolerance
|
|
CN107617110A
(zh)
|
2009-08-26 |
2018-01-23 |
西莱克塔生物科技公司 |
诱导t细胞辅助的组合物
|
|
EP2504311B1
(en)
*
|
2009-11-25 |
2015-08-12 |
Cytometix, Inc. |
Arachidonic acid analogs and methods for analgesic treatment using same
|
|
ES2780156T3
(es)
|
2009-12-15 |
2020-08-24 |
Pfizer |
Composiciones terapéuticas de nanopartículas poliméricas con alta temperatura de transición vítrea o copolímeros de alto peso molecular
|
|
WO2011085231A2
(en)
|
2010-01-08 |
2011-07-14 |
Selecta Biosciences, Inc. |
Synthetic virus-like particles conjugated to human papillomavirus capsid peptides for use as vaccines
|
|
US20110229556A1
(en)
|
2010-03-19 |
2011-09-22 |
Massachusetts Institute Of Technology |
Lipid-coated polymer particles for immune stimulation
|
|
US20110272836A1
(en)
|
2010-04-12 |
2011-11-10 |
Selecta Biosciences, Inc. |
Eccentric vessels
|
|
US20110262491A1
(en)
|
2010-04-12 |
2011-10-27 |
Selecta Biosciences, Inc. |
Emulsions and methods of making nanocarriers
|
|
AU2011258165B2
(en)
|
2010-05-26 |
2016-11-17 |
Selecta Biosciences, Inc. |
Dose selection of adjuvanted synthetic nanocarriers
|
|
US20120058153A1
(en)
|
2010-08-20 |
2012-03-08 |
Selecta Biosciences, Inc. |
Synthetic nanocarrier vaccines comprising proteins obtained or derived from human influenza a virus hemagglutinin
|
|
BR112013004288A2
(pt)
|
2010-08-23 |
2016-05-31 |
Selecta Biosciences Inc |
formas galênicas de múltiplos epítopos direcionados para indução de uma resposta imunológica a antigênios.
|
|
WO2012061717A1
(en)
|
2010-11-05 |
2012-05-10 |
Selecta Biosciences, Inc. |
Modified nicotinic compounds and related methods
|
|
WO2012092552A1
(en)
|
2010-12-30 |
2012-07-05 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers with reactive groups that release biologically active agents
|
|
CA2830948A1
(en)
|
2011-03-25 |
2012-10-04 |
Selecta Biosciences, Inc. |
Osmotic mediated release synthetic nanocarriers
|
|
KR20140041505A
(ko)
|
2011-04-29 |
2014-04-04 |
셀렉타 바이오사이언시즈, 인크. |
조절 b 세포 유도를 위한 관용원성 합성 나노운반체
|
|
JP2014521687A
(ja)
|
2011-07-29 |
2014-08-28 |
セレクタ バイオサイエンシーズ インコーポレーテッド |
体液性および細胞傷害性ｔリンパ球（ｃｔｌ）免疫応答を生成する合成ナノキャリア
|
|
US20130058901A1
(en)
|
2011-09-06 |
2013-03-07 |
Selecta Biosciences, Inc. |
Transplantable graft-specific induced tolerogenic dendritic cells and methods of use
|
|
HUE052599T2
(hu)
|
2013-05-03 |
2021-05-28 |
Selecta Biosciences Inc |
CD4+ szabályozó T-sejtek fokozására szolgáló eljárások és készítmények
|
|
IL295392A
(en)
|
2013-06-04 |
2022-10-01 |
Selecta Biosciences Inc |
Repeated administration of non-immunosupressive antigen specific immunotherapeutics
|
|
US20150359865A1
(en)
|
2014-06-17 |
2015-12-17 |
Selecta Biosciences, Inc. |
Tolerogenic synthetic nanocarriers for t-cell-mediated autoimmune disease
|
|
US20160220501A1
(en)
|
2015-02-03 |
2016-08-04 |
Selecta Biosciences, Inc. |
Tolerogenic synthetic nanocarriers to reduce immune responses to therapeutic proteins
|
|
AU2015279738A1
(en)
|
2014-06-25 |
2016-12-22 |
Selecta Biosciences, Inc. |
Methods and compositions for treatment with synthetic nanocarriers and immune checkpoint inhibitors
|
|
AU2015311704B2
(en)
|
2014-09-07 |
2021-12-09 |
Selecta Biosciences, Inc. |
Methods and compositions for attenuating gene editing anti-viral transfer vector immune responses
|
|
ES2977259T3
(es)
|
2014-11-05 |
2024-08-21 |
Cartesian Therapeutics Inc |
Métodos y composiciones relacionadas con nanovehículos sintéticos con rapamicina en un estado sobresaturado estable
|