JP2015531773A5 - - Google Patents
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- JP2015531773A5 JP2015531773A5 JP2015529005A JP2015529005A JP2015531773A5 JP 2015531773 A5 JP2015531773 A5 JP 2015531773A5 JP 2015529005 A JP2015529005 A JP 2015529005A JP 2015529005 A JP2015529005 A JP 2015529005A JP 2015531773 A5 JP2015531773 A5 JP 2015531773A5
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- 229910052739 hydrogen Inorganic materials 0.000 claims description 54
- 125000000217 alkyl group Chemical group 0.000 claims description 31
- 150000001875 compounds Chemical class 0.000 claims description 31
- 125000001424 substituent group Chemical group 0.000 claims description 24
- 229910052757 nitrogen Inorganic materials 0.000 claims description 23
- 125000005842 heteroatom Chemical group 0.000 claims description 22
- 239000001257 hydrogen Substances 0.000 claims description 21
- 150000003839 salts Chemical class 0.000 claims description 19
- 125000005843 halogen group Chemical group 0.000 claims description 18
- 229910052760 oxygen Inorganic materials 0.000 claims description 18
- 229910052717 sulfur Inorganic materials 0.000 claims description 17
- 239000012453 solvate Substances 0.000 claims description 16
- 125000003545 alkoxy group Chemical group 0.000 claims description 12
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical group C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 claims description 10
- 125000003118 aryl group Chemical group 0.000 claims description 5
- 208000015181 infectious disease Diseases 0.000 claims description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 5
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims description 5
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 5
- 229930192474 thiophene Chemical group 0.000 claims description 5
- 229910052736 halogen Inorganic materials 0.000 claims description 4
- 150000002367 halogens Chemical class 0.000 claims description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 3
- 241000124008 Mammalia Species 0.000 claims description 3
- 229910052799 carbon Inorganic materials 0.000 claims description 3
- 125000002950 monocyclic group Chemical group 0.000 claims description 3
- 239000008194 pharmaceutical composition Substances 0.000 claims description 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 2
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- 239000003112 inhibitor Substances 0.000 claims description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 2
- 125000004430 oxygen atom Chemical group O* 0.000 claims description 2
- 230000002265 prevention Effects 0.000 claims description 2
- 125000002837 carbocyclic group Chemical group 0.000 claims 19
- 150000002431 hydrogen Chemical class 0.000 claims 5
- 125000001153 fluoro group Chemical group F* 0.000 claims 2
- 230000001548 androgenic effect Effects 0.000 claims 1
- 150000001721 carbon Chemical group 0.000 claims 1
- 125000001309 chloro group Chemical group Cl* 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 125000003003 spiro group Chemical group 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 description 18
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 14
- 125000004432 carbon atom Chemical group C* 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018207904A JP6895938B2 (ja) | 2012-08-28 | 2018-11-05 | スルファモイル−アリールアミド及びｂ型肝炎の治療のための薬剤としてのその使用 |
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12182076 | 2012-08-28 | ||
| EP12185055.6 | 2012-09-19 | ||
| EP12185055 | 2012-09-19 | ||
| EP12190837.0 | 2012-10-31 | ||
| EP12190837 | 2012-10-31 | ||
| EP13157230 | 2013-02-28 | ||
| EP13157230.7 | 2013-02-28 | ||
| EP13169574.4 | 2013-05-28 | ||
| EP13169574 | 2013-05-28 | ||
| EP12182076.5 | 2013-08-23 | ||
| PCT/EP2013/067821 WO2014033170A1 (en) | 2012-08-28 | 2013-08-28 | Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis b |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018207904A Division JP6895938B2 (ja) | 2012-08-28 | 2018-11-05 | スルファモイル−アリールアミド及びｂ型肝炎の治療のための薬剤としてのその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015531773A JP2015531773A (ja) | 2015-11-05 |
| JP2015531773A5 true JP2015531773A5 (OSRAM) | 2018-03-01 |
| JP6505013B2 JP6505013B2 (ja) | 2019-04-24 |
Family
ID=49085019
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015529007A Withdrawn JP2015533782A (ja) | 2012-08-28 | 2013-08-28 | スルファモイル−アリールアミド及びｂ型肝炎の治療のための薬剤としてのその使用 |
| JP2015529005A Expired - Fee Related JP6505013B2 (ja) | 2012-08-28 | 2013-08-28 | スルファモイル−アリールアミド及びｂ型肝炎の治療のための薬剤としてのその使用 |
| JP2018207904A Expired - Fee Related JP6895938B2 (ja) | 2012-08-28 | 2018-11-05 | スルファモイル−アリールアミド及びｂ型肝炎の治療のための薬剤としてのその使用 |
| JP2018208063A Expired - Fee Related JP6907173B2 (ja) | 2012-08-28 | 2018-11-05 | スルファモイル−アリールアミド及びｂ型肝炎の治療のための薬剤としてのその使用 |
| JP2021095380A Withdrawn JP2021176846A (ja) | 2012-08-28 | 2021-06-07 | スルファモイル−アリールアミド及びｂ型肝炎の治療のための薬剤としてのその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015529007A Withdrawn JP2015533782A (ja) | 2012-08-28 | 2013-08-28 | スルファモイル−アリールアミド及びｂ型肝炎の治療のための薬剤としてのその使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018207904A Expired - Fee Related JP6895938B2 (ja) | 2012-08-28 | 2018-11-05 | スルファモイル−アリールアミド及びｂ型肝炎の治療のための薬剤としてのその使用 |
| JP2018208063A Expired - Fee Related JP6907173B2 (ja) | 2012-08-28 | 2018-11-05 | スルファモイル−アリールアミド及びｂ型肝炎の治療のための薬剤としてのその使用 |
| JP2021095380A Withdrawn JP2021176846A (ja) | 2012-08-28 | 2021-06-07 | スルファモイル−アリールアミド及びｂ型肝炎の治療のための薬剤としてのその使用 |
Country Status (27)
| Country | Link |
|---|---|
| US (5) | US10676429B2 (OSRAM) |
| EP (2) | EP2890375B1 (OSRAM) |
| JP (5) | JP2015533782A (OSRAM) |
| KR (4) | KR20210081451A (OSRAM) |
| CN (4) | CN113321632A (OSRAM) |
| AP (2) | AP2015008248A0 (OSRAM) |
| AR (2) | AR092270A1 (OSRAM) |
| AU (5) | AU2013307331A1 (OSRAM) |
| BR (2) | BR112015004192B1 (OSRAM) |
| CA (2) | CA2880699A1 (OSRAM) |
| CL (2) | CL2015000488A1 (OSRAM) |
| CR (2) | CR20200276A (OSRAM) |
| EA (2) | EA027280B1 (OSRAM) |
| EC (2) | ECSP15007335A (OSRAM) |
| GT (2) | GT201500020A (OSRAM) |
| HK (2) | HK1210030A1 (OSRAM) |
| IL (3) | IL236967A0 (OSRAM) |
| JO (1) | JOP20130256B1 (OSRAM) |
| MX (2) | MX375789B (OSRAM) |
| NI (2) | NI201500029A (OSRAM) |
| NZ (4) | NZ743499A (OSRAM) |
| PH (3) | PH12015500317A1 (OSRAM) |
| SG (4) | SG10201709133QA (OSRAM) |
| TW (4) | TW201920090A (OSRAM) |
| UA (2) | UA122385C2 (OSRAM) |
| UY (2) | UY34992A (OSRAM) |
| WO (2) | WO2014033176A1 (OSRAM) |
Families Citing this family (162)
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| SG11201504740UA (en) | 2012-12-27 | 2015-07-30 | Univ Drexel | Novel antiviral agents against hbv infection |
| ES2628953T3 (es) | 2013-02-28 | 2017-08-04 | Janssen Sciences Ireland Uc | Sulfamoilarilamidas y el uso de las mismas como medicamentos para el tratamiento de la hepatitis B |
| WO2014165128A2 (en) | 2013-03-12 | 2014-10-09 | Novira Therapeutics, Inc. | Hepatitis b antiviral agents |
| MX353412B (es) | 2013-04-03 | 2018-01-10 | Janssen Sciences Ireland Uc | Derivados de n-fenil-carboxamida y su uso como medicamentos para el tratamiento de la hepatitis b. |
| JP6441315B2 (ja) | 2013-05-17 | 2018-12-19 | ヤンセン・サイエンシズ・アイルランド・ユーシー | スルファモイルチオフェンアミド誘導体およびｂ型肝炎を治療するための医薬品としてのその使用 |
| JO3603B1 (ar) | 2013-05-17 | 2020-07-05 | Janssen Sciences Ireland Uc | مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي |
| PL3024819T3 (pl) | 2013-07-25 | 2018-08-31 | Janssen Sciences Ireland Uc | Pochodne piroloamidowe podstawione glioksamidem i ich zastosowanie jako leków do leczenia wirusowego zapalenia wątroby typu B |
| SG11201602748XA (en) | 2013-10-23 | 2016-05-30 | Janssen Sciences Ireland Uc | Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b |
| US10392349B2 (en) | 2014-01-16 | 2019-08-27 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
| US9169212B2 (en) | 2014-01-16 | 2015-10-27 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
| US9181288B2 (en) | 2014-01-16 | 2015-11-10 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
| KR20160128305A (ko) | 2014-02-05 | 2016-11-07 | 노비라 테라퓨틱스, 인코포레이티드 | Hbv 감염의 치료를 위한 병용 요법 |
| ES2705401T3 (es) | 2014-02-06 | 2019-03-25 | Janssen Sciences Ireland Uc | Derivados de sulfamoilpirrolamida y su uso como medicamentos para el tratamiento de la Hepatitis B |
| PT3116316T (pt) | 2014-03-13 | 2019-09-30 | Assembly Biosciences Inc | Moduladores alostéricos da proteína do núcleo da hepatite b |
| US9400280B2 (en) | 2014-03-27 | 2016-07-26 | Novira Therapeutics, Inc. | Piperidine derivatives and methods of treating hepatitis B infections |
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