|
US4179337A
(en)
|
1973-07-20 |
1979-12-18 |
Davis Frank F |
Non-immunogenic polypeptides
|
|
US4230691A
(en)
|
1978-05-23 |
1980-10-28 |
The Massachusetts General Hospital |
Nerve growth factor antibody and process
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US6548640B1
(en)
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
|
GB8725529D0
(en)
|
1987-10-30 |
1987-12-02 |
Delta Biotechnology Ltd |
Polypeptides
|
|
US5683894A
(en)
|
1988-04-29 |
1997-11-04 |
University Of California |
Recombinant nerve growth factor
|
|
US6440928B1
(en)
|
1988-12-06 |
2002-08-27 |
Colorado State University Research Foundation |
Method for treating diabetic neuropathy with NGF
|
|
CA2006596C
(en)
|
1988-12-22 |
2000-09-05 |
Rika Ishikawa |
Chemically-modified g-csf
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5766883A
(en)
|
1989-04-29 |
1998-06-16 |
Delta Biotechnology Limited |
Polypeptides
|
|
US6262239B1
(en)
|
1989-05-18 |
2001-07-17 |
Yeda Research And Development Co., Ltd. |
TNF receptor-specific antibodies
|
|
FR2650598B1
(fr)
|
1989-08-03 |
1994-06-03 |
Rhone Poulenc Sante |
Derives de l'albumine a fonction therapeutique
|
|
US5656435A
(en)
|
1989-08-28 |
1997-08-12 |
Takeda Chemical Industries, Ltd. |
Antibodies to peptides having NGF-like activity, said antibodies having no substantial cross-reactivity with NGF, and use thereof
|
|
US5180820A
(en)
|
1989-08-30 |
1993-01-19 |
Barde Yves Alain |
Brain-derived neurotrophic factor
|
|
US5672683A
(en)
|
1989-09-07 |
1997-09-30 |
Alkermes, Inc. |
Transferrin neuropharmaceutical agent fusion protein
|
|
US5977307A
(en)
|
1989-09-07 |
1999-11-02 |
Alkermes, Inc. |
Transferrin receptor specific ligand-neuropharmaceutical agent fusion proteins
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
EP0542810A1
(en)
|
1990-08-02 |
1993-05-26 |
B.R. Centre Limited |
Methods for the production of proteins with a desired function
|
|
US6566091B1
(en)
|
1990-09-25 |
2003-05-20 |
Genentech, Inc. |
Neurotrophic factor
|
|
US6506728B2
(en)
|
1990-09-25 |
2003-01-14 |
Genentech, Inc. |
Methods using a novel neurotrophic factor, NT-4
|
|
US5604202A
(en)
|
1990-11-13 |
1997-02-18 |
Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University |
Use of NGF growth factors to treat drug-induced neuropathy
|
|
WO1992009690A2
(en)
|
1990-12-03 |
1992-06-11 |
Genentech, Inc. |
Enrichment method for variant proteins with altered binding properties
|
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
DE122004000008I1
(de)
|
1991-06-14 |
2005-06-09 |
Genentech Inc |
Humanisierter Heregulin Antikörper.
|
|
FR2686899B1
(fr)
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
|
US6063625A
(en)
|
1993-02-12 |
2000-05-16 |
Board Of Trustees Of Leland S, Stanford, Jr. University |
Regulated transcription of targeted genes and other biological events
|
|
US5869337A
(en)
|
1993-02-12 |
1999-02-09 |
President And Fellows Of Harvard College |
Regulated transcription of targeted genes and other biological events
|
|
US5830462A
(en)
|
1993-02-12 |
1998-11-03 |
President & Fellows Of Harvard College |
Regulated transcription of targeted genes and other biological events
|
|
AU6445894A
(en)
|
1993-03-19 |
1994-10-11 |
Duke University |
Method of treatment of tumors with an antibody binding to tenascin
|
|
DE69430824T2
(de)
|
1993-08-12 |
2003-01-23 |
Neurotech S.A., Evry |
Biokompatible immunoisolatorische Kapseln, die genetisch veränderte Zellen enthalten
|
|
US5908623A
(en)
|
1993-08-12 |
1999-06-01 |
Cytotherapeutics, Inc. |
Compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
|
|
US6562596B1
(en)
|
1993-10-06 |
2003-05-13 |
Amgen Inc. |
Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods
|
|
US5643575A
(en)
|
1993-10-27 |
1997-07-01 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
|
US5753225A
(en)
|
1993-12-03 |
1998-05-19 |
The Regents Of The University Of California |
Antibodies that mimic actions of neurotrophins
|
|
CA2179014C
(en)
|
1993-12-17 |
2003-07-29 |
Spinal Cord Society |
Method for inducing dna synthesis in neurons
|
|
GB9402331D0
(en)
|
1994-02-07 |
1994-03-30 |
Univ Mcgill |
Nerve growth factor structural analogs and their uses
|
|
US6551618B2
(en)
|
1994-03-15 |
2003-04-22 |
University Of Birmingham |
Compositions and methods for delivery of agents for neuronal regeneration and survival
|
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
|
US5844092A
(en)
|
1994-03-18 |
1998-12-01 |
Genentech, Inc. |
Human TRK receptors and neurotrophic factor inhibitors
|
|
US6024734A
(en)
|
1994-03-31 |
2000-02-15 |
Brewitt; Barbara A. |
Treatment methods using homeopathic preparations of growth factors
|
|
US6291247B1
(en)
|
1994-05-11 |
2001-09-18 |
Queen's University At Kingston |
Methods of screening for factors that disrupt neurotrophin conformation and reduce neurotrophin biological activity
|
|
US7144983B1
(en)
|
1997-02-03 |
2006-12-05 |
Genentech, Inc. |
Pantropic neurotrophic factors
|
|
US5728803A
(en)
|
1994-06-03 |
1998-03-17 |
Genentech, Inc. |
Pantropic neurotrophic factors
|
|
US5776747A
(en)
|
1994-07-20 |
1998-07-07 |
Cytotherapeutics, Inc. |
Method for controlling the distribution of cells within a bioartificial organ using polycthylene oxide-poly (dimethylsiloxane) copolymer
|
|
IL114909A
(en)
|
1994-08-12 |
1999-10-28 |
Immunomedics Inc |
Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
|
|
US6271205B1
(en)
|
1994-09-21 |
2001-08-07 |
University Of Massachusetts Medical Center |
Cancer treatment by expression of differentiation factor receptor
|
|
US5759775A
(en)
|
1994-10-27 |
1998-06-02 |
Genetech, Inc. |
Methods for detecting nucleic acids encoding AL--1 neurotrophic factor
|
|
US6096716A
(en)
|
1994-12-12 |
2000-08-01 |
The Board Of Regents, The University Of Texas System |
Liposome-mediated transfection of central nervous system cells
|
|
US6211142B1
(en)
|
1995-03-10 |
2001-04-03 |
Genentech, Inc. |
Compositions comprising gas6 polypeptides and articles of manufacture comprising the same
|
|
US5688911A
(en)
|
1995-05-03 |
1997-11-18 |
Schneider; Rainer |
Trk neurotrophin binding motifs
|
|
US6717031B2
(en)
|
1995-06-07 |
2004-04-06 |
Kate Dora Games |
Method for selecting a transgenic mouse model of alzheimer's disease
|
|
US5731284A
(en)
|
1995-09-28 |
1998-03-24 |
Amgen Inc. |
Method for treating Alzheimer's disease using glial line-derived neurotrophic factor (GDNF) protein product
|
|
US20020090682A1
(en)
|
1995-10-23 |
2002-07-11 |
Tracy Willson |
Novel haemopoietin receptor and genetic sequences encoding same
|
|
US6610296B2
(en)
|
1995-10-26 |
2003-08-26 |
Genentech, Inc. |
Methods of enhancing cognitive function using an AL-1 neurotrophic factor immunoadhesin
|
|
GB9525180D0
(en)
|
1995-12-08 |
1996-02-07 |
Univ Mcgill |
Design of hormone-like antibodies with agonistic and antagonistic fuctions
|
|
US6406710B1
(en)
|
1996-01-16 |
2002-06-18 |
Nikos Panayotatos |
Protein occlusion for delivery of small molecules
|
|
WO1997026275A1
(en)
|
1996-01-16 |
1997-07-24 |
Nikos Panayotatos |
Protein occlusion for delivery of small molecules
|
|
US6299895B1
(en)
|
1997-03-24 |
2001-10-09 |
Neurotech S.A. |
Device and method for treating ophthalmic diseases
|
|
GB9608335D0
(en)
|
1996-04-23 |
1996-06-26 |
Univ Kingston |
Method of enhancing ngf-mediated neurite growth with low molecular weight analoues of p.75 ngfr 367-379
|
|
US6653104B2
(en)
|
1996-10-17 |
2003-11-25 |
Immunomedics, Inc. |
Immunotoxins, comprising an internalizing antibody, directed against malignant and normal cells
|
|
CA2277955A1
(en)
|
1997-01-23 |
1998-07-30 |
Michiko Kishino |
Remedies for diabetes
|
|
US6777196B2
(en)
|
1997-02-18 |
2004-08-17 |
Genentech, Inc. |
Neurturin receptor
|
|
US6365373B2
(en)
|
1997-04-25 |
2002-04-02 |
Genentech, Inc. |
Nucleic acids encoding NGF variants
|
|
US7452863B1
(en)
|
1997-04-29 |
2008-11-18 |
Genentech, Inc. |
NGF variants
|
|
DE69829287T2
(de)
|
1997-06-30 |
2006-04-13 |
Centre National De La Recherche Scientifique (Cnrs) |
Verbesserung der verabreichung der nukleinsäure in zellen der plurizellulären eukaryotischen organismen und kombination zur durchführung des verfahrens
|
|
JP2002507985A
(ja)
|
1997-06-30 |
2002-03-12 |
ローヌ−プーラン・ロレ・エス・アー |
横紋筋に核酸を導入する改良法およびその組合せ
|
|
US6063768A
(en)
|
1997-09-04 |
2000-05-16 |
First; Eric R. |
Application of botulinum toxin to the management of neurogenic inflammatory disorders
|
|
US5990129A
(en)
|
1997-09-23 |
1999-11-23 |
Eli Lilly And Company |
Methods for regulating trkA expression
|
|
US5968921A
(en)
|
1997-10-24 |
1999-10-19 |
Orgegon Health Sciences University |
Compositions and methods for promoting nerve regeneration
|
|
US5928174A
(en)
|
1997-11-14 |
1999-07-27 |
Acrymed |
Wound dressing device
|
|
US7282482B2
(en)
|
1998-04-08 |
2007-10-16 |
The Regents Of The University Of California |
NGF for the prevention of demyelination in the nervous system
|
|
US20030096753A1
(en)
|
1998-04-09 |
2003-05-22 |
Robertson Alan George Simpson |
Therapeutic agent
|
|
GB9807781D0
(en)
|
1998-04-09 |
1998-06-10 |
Univ Bristol |
Therapeutic agent
|
|
US6866842B1
(en)
|
1998-05-01 |
2005-03-15 |
University Of Pittsburgh |
Muscle-derived cells (MDCs) for treating muscle-or bone-related injury or dysfunction
|
|
US6428579B1
(en)
|
1998-07-01 |
2002-08-06 |
Brown University Research Foundation |
Implantable prosthetic devices coated with bioactive molecules
|
|
AU6151899A
(en)
|
1998-09-23 |
2000-04-10 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
Methods of treating chronic pain
|
|
US6506599B1
(en)
|
1999-10-15 |
2003-01-14 |
Tai-Wook Yoon |
Method for culturing langerhans islets and islet autotransplantation islet regeneration
|
|
US6680292B1
(en)
|
1998-11-20 |
2004-01-20 |
The Salk Institute For Biological Studies |
Pharmaceutical composition comprising ribavirin and growth factors and methods of use
|
|
US6927024B2
(en)
|
1998-11-30 |
2005-08-09 |
Genentech, Inc. |
PCR assay
|
|
US6652864B1
(en)
|
1998-12-21 |
2003-11-25 |
Asilomar Pharmaceuticals, Inc. |
Compounds for intracellular delivery of therapeutic moieties to nerve cells
|
|
US7115261B1
(en)
|
1999-02-12 |
2006-10-03 |
The Scripps Research Institute |
Methods for treatment of tumors and metastases using a combination of anti-angiogenic and immuno therapies
|
|
US6943153B1
(en)
|
1999-03-15 |
2005-09-13 |
The Regents Of The University Of California |
Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
|
|
US7527787B2
(en)
|
2005-10-19 |
2009-05-05 |
Ibc Pharmaceuticals, Inc. |
Multivalent immunoglobulin-based bioactive assemblies
|
|
US7534866B2
(en)
|
2005-10-19 |
2009-05-19 |
Ibc Pharmaceuticals, Inc. |
Methods and compositions for generating bioactive assemblies of increased complexity and uses
|
|
US8119101B2
(en)
|
1999-05-10 |
2012-02-21 |
The Ohio State University |
Anti-CD74 immunoconjugates and methods of use
|
|
US7550143B2
(en)
|
2005-04-06 |
2009-06-23 |
Ibc Pharmaceuticals, Inc. |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses
|
|
US8383081B2
(en)
|
1999-05-10 |
2013-02-26 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods of use
|
|
IT1306704B1
(it)
|
1999-05-26 |
2001-10-02 |
Sirs Societa Italiana Per La R |
Anticorpi monoclonali e suoi derivati sintetici o biotecnologici ingrado di agire come molecole antagoniste per il ngf.
|
|
US20020177120A1
(en)
|
1999-06-04 |
2002-11-28 |
Kathryn J. Elliott |
Assays for apotosis modulators
|
|
US20030152562A1
(en)
|
2001-10-23 |
2003-08-14 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Vitro micro-organs, and uses related thereto
|
|
US8106098B2
(en)
|
1999-08-09 |
2012-01-31 |
The General Hospital Corporation |
Protein conjugates with a water-soluble biocompatible, biodegradable polymer
|
|
US6503713B1
(en)
|
1999-10-04 |
2003-01-07 |
University Of Medicine And Dentistry Of New Jersey |
Methods for identifying RNA binding compounds
|
|
KR100416242B1
(ko)
|
1999-12-22 |
2004-01-31 |
주식회사 삼양사 |
약물전달체용 생분해성 블록 공중합체의 액체 조성물 및이의 제조방법
|
|
US6548062B2
(en)
|
2000-02-29 |
2003-04-15 |
Cephalon, Inc. |
Method of treating cancer with anti-neurotrophin agents
|
|
SI2857516T1
(sl)
|
2000-04-11 |
2017-09-29 |
Genentech, Inc. |
Multivalentna protitelesa in njihove uporabe
|
|
FR2807660A1
(fr)
|
2000-04-13 |
2001-10-19 |
Warner Lambert Co |
Utilisation d'antagonistes du ngf pour la prevention ou le traitement de douleurs viscerales chroniques
|
|
US20040058393A1
(en)
|
2000-04-17 |
2004-03-25 |
Naoshi Fukishima |
Agonist antibodies
|
|
US7473555B2
(en)
|
2000-04-27 |
2009-01-06 |
Geron Corporation |
Protocols for making hepatocytes from embryonic stem cells
|
|
US6686196B2
(en)
|
2000-05-03 |
2004-02-03 |
University Of Washington |
Recombinant, modified adenoviral vectors for tumor specific gene expression and uses thereof
|
|
IL153375A0
(en)
|
2000-06-22 |
2003-07-06 |
Genentech Inc |
Agonist anti-trk-c monoclonal antibodies
|
|
WO2002004448A2
(en)
|
2000-07-07 |
2002-01-17 |
Neotherapeutics, Inc. |
Methods for treatment of drug-induced peripheral neuropathy and related conditions
|
|
US20020164333A1
(en)
|
2000-07-10 |
2002-11-07 |
The Scripps Research Institute |
Bifunctional molecules and vectors complexed therewith for targeted gene delivery
|
|
US6719970B1
(en)
|
2000-07-10 |
2004-04-13 |
Alkermes Controlled Therapeutics, Inc. |
Method of generating cartilage
|
|
WO2002003922A2
(en)
|
2000-07-11 |
2002-01-17 |
Lipps Binie V |
Synthetic peptide for neurological disorders
|
|
US20070122904A1
(en)
|
2000-09-29 |
2007-05-31 |
Unisearch Limited |
Method and apparatus for culturing cells
|
|
KR100870123B1
(ko)
|
2000-10-20 |
2008-11-25 |
츄가이 세이야꾸 가부시키가이샤 |
저분자화 아고니스트 항체
|
|
US20020128179A1
(en)
|
2000-12-01 |
2002-09-12 |
Tacon William C. |
Shaped microparticles for pulmonary drug delivery
|
|
US20020115173A1
(en)
|
2000-12-11 |
2002-08-22 |
Children's Medical Center Corporation |
Short peptides from the 'A-region' of protein kinases which selectively modulate protein kinase activity
|
|
US7169568B2
(en)
|
2000-12-18 |
2007-01-30 |
New York University |
Method for screening molecules that exert a neurotrophic effect through activation of neurotrophin receptors
|
|
DE10101546B4
(de)
|
2001-01-15 |
2005-04-28 |
Man Technologie Gmbh |
Verfahren zur Herstellung einer hochtemperaturfesten Faserverbundkeramik und so hergestellte Bauteile
|
|
US6602241B2
(en)
|
2001-01-17 |
2003-08-05 |
Transvascular, Inc. |
Methods and apparatus for acute or chronic delivery of substances or apparatus to extravascular treatment sites
|
|
US20040115671A1
(en)
|
2001-01-18 |
2004-06-17 |
Zlokovic Berislav V |
Gene expression profiling of endothelium in alzheimer's disease
|
|
US6551578B2
(en)
|
2001-02-15 |
2003-04-22 |
Aeropharm Technology Incorporated |
Modulated release particles for aerosol delivery
|
|
US6749845B2
(en)
|
2001-02-15 |
2004-06-15 |
Aeropharm Technology, Inc. |
Modulated release particles for lung delivery
|
|
US6485707B2
(en)
|
2001-02-15 |
2002-11-26 |
Aeropharm Technology Incorporated |
Modulated release particles for aerosol delivery
|
|
US6475468B2
(en)
|
2001-02-15 |
2002-11-05 |
Aeropharm Technology Incorporated |
Modulated release particles for aerosol delivery
|
|
US6596262B2
(en)
|
2001-02-15 |
2003-07-22 |
Aeropharm Technology Incorporated |
Modulated release particles for aerosol delivery
|
|
US6544497B2
(en)
|
2001-02-15 |
2003-04-08 |
Aeropharm Technology Incorporated |
Modulated release particles for aerosol delivery
|
|
US7029916B2
(en)
|
2001-02-21 |
2006-04-18 |
Maxcyte, Inc. |
Apparatus and method for flow electroporation of biological samples
|
|
AU2002257703A1
(en)
|
2001-03-23 |
2002-10-08 |
Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh |
Use of cytokines of the tgf-beta superfamily for the treatment and diagnosis of skin related disorders
|
|
AU2002338348A1
(en)
|
2001-04-06 |
2002-10-21 |
Biovision Ag |
Method for detecting chronic dementia diseases, and corresponding peptides and detection reagents
|
|
CA2447986A1
(en)
|
2001-05-25 |
2002-12-05 |
Cornell Research Foundation, Inc. |
High affinity ligand for p75 neurotrophin receptor
|
|
JP2002348234A
(ja)
|
2001-05-28 |
2002-12-04 |
Purotekku:Kk |
薬物封入無機物微粒子、その製造法及び薬物封入無機物微粒子製剤
|
|
ATE522229T1
(de)
|
2001-05-30 |
2011-09-15 |
Genentech Inc |
Anti-ngf-antikörper zur behandlung verschiedener erkrankungen
|
|
WO2002102232A2
(en)
|
2001-06-14 |
2002-12-27 |
The Regents Of The University Of California |
A novel signaling pathway for the production of inflammatory pain and neuropathy
|
|
AU2002323151A1
(en)
|
2001-08-13 |
2003-03-03 |
University Of Pittsburgh |
Application of lipid vehicles and use for drug delivery
|
|
US7141425B2
(en)
|
2001-08-22 |
2006-11-28 |
Maxcyte, Inc. |
Apparatus and method for electroporation of biological samples
|
|
JP2005512592A
(ja)
|
2001-12-21 |
2005-05-12 |
マウント・シナイ・ホスピタル |
細胞性組成物ならびに細胞性組成物の作製法および細胞性組成物の使用法
|
|
US20050142539A1
(en)
|
2002-01-14 |
2005-06-30 |
William Herman |
Targeted ligands
|
|
EP2075256A2
(en)
|
2002-01-14 |
2009-07-01 |
William Herman |
Multispecific binding molecules
|
|
IL152904A0
(en)
|
2002-01-24 |
2003-06-24 |
Gamida Cell Ltd |
Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
|
|
CA2369810C
(en)
|
2002-01-30 |
2007-08-07 |
1474791 Ontario Limited |
Method of treating pain
|
|
WO2003066821A2
(en)
|
2002-02-04 |
2003-08-14 |
The Johns Hopkins University |
Molecules interacting with casl (mical) polynucleotides, polypeptides, and methods of using the same
|
|
US8491896B2
(en)
|
2002-06-14 |
2013-07-23 |
Immunomedics, Inc. |
Anti-pancreatic cancer antibodies
|
|
WO2003072753A2
(en)
|
2002-02-27 |
2003-09-04 |
Emory University |
Multimeric binding complexes
|
|
CA2479679A1
(en)
|
2002-03-18 |
2003-09-25 |
Gamida-Cell Ltd. |
Methods of inducing differentiation in ex vivo expanded stem cells
|
|
US20040009589A1
(en)
|
2002-03-26 |
2004-01-15 |
Shulamit Levenberg |
Endothelial cells derived from human embryonic stem cells
|
|
US20060093589A1
(en)
|
2004-02-19 |
2006-05-04 |
Warrington Kenneth H |
Vp2-modified raav vector compositions and uses therefor
|
|
NZ536274A
(en)
|
2002-05-01 |
2008-04-30 |
Univ Florida |
Improved rAAV expression systems for genetic modification of specific capsid proteins
|
|
US20030235580A1
(en)
|
2002-06-24 |
2003-12-25 |
Fen Zhang |
Amniotic membrane mediated delivery of bioactive molecules
|
|
EP2135879A3
(en)
|
2002-06-28 |
2010-06-23 |
Domantis Limited |
Ligand
|
|
JP2005537244A
(ja)
|
2002-06-28 |
2005-12-08 |
ナステック・ファーマシューティカル・カンパニー・インコーポレーテッド |
療法化合物の粘膜搬送を増進させるための、上皮接合部接着分子の生理機能を調節する組成物および方法
|
|
WO2004009774A2
(en)
|
2002-07-19 |
2004-01-29 |
Amgen Inc. |
Protein conjugates with a water-soluble biocompatible, biogradable polymer
|
|
US8263375B2
(en)
|
2002-12-20 |
2012-09-11 |
Acea Biosciences |
Dynamic monitoring of activation of G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK) in living cells using real-time microelectronic cell sensing technology
|
|
US7745151B2
(en)
|
2002-08-02 |
2010-06-29 |
Children's Medical Center Corporation |
Methods of determining binding between Nogo receptor and p75 neurotrophin receptor
|
|
US20050074865A1
(en)
|
2002-08-27 |
2005-04-07 |
Compound Therapeutics, Inc. |
Adzymes and uses thereof
|
|
US6919426B2
(en)
|
2002-09-19 |
2005-07-19 |
Amgen Inc. |
Peptides and related molecules that modulate nerve growth factor activity
|
|
CA2501068C
(en)
|
2002-10-04 |
2014-12-16 |
Kirin Beer Kabushiki Kaisha |
Human artificial chromosome (hac) vector
|
|
WO2004032852A2
(en)
|
2002-10-04 |
2004-04-22 |
Rinat Neuroscience Corp. |
Methods for treating cardiac arrhythmia and preventing death due to cardiac arrhythmia using ngf antagonists
|
|
UA80447C2
(en)
|
2002-10-08 |
2007-09-25 |
|
Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic
|
|
ES2357948T3
(es)
*
|
2002-10-08 |
2011-05-04 |
Rinat Neuroscience Corp. |
Procedimientos para tratar dolor postquirúrgico mediante la administración de un anticuerpo frente al factor de crecimiento nervioso y composiciones que contienen el mismo.
|
|
AU2003304238A1
(en)
|
2002-10-08 |
2005-01-13 |
Rinat Neuroscience Corp. |
Methods for treating post-surgical pain by administering an anti-nerve growth factor antagonist antibody and compositions containing the same
|
|
PL376473A1
(en)
|
2002-10-22 |
2005-12-27 |
Waratah Pharmaceuticals, Inc. |
Treatment of diabetes
|
|
FR2846426B1
(fr)
|
2002-10-28 |
2004-12-10 |
Bio Merieux |
Procede de dosage du ngf pour le diagnostic in vitro du cancer du sein et utilisation en therapie
|
|
US20050054097A1
(en)
|
2002-11-17 |
2005-03-10 |
Tony Peled |
EX-VIVO expansion of hematopoietic system cell populations in mononuclear cell cultures
|
|
US8066997B2
(en)
|
2002-12-20 |
2011-11-29 |
Anders Nykjaer |
Modulation of activity of neurotrophins
|
|
CA2921578C
(en)
|
2002-12-24 |
2017-02-14 |
Rinat Neuroscience Corp. |
Anti-ngf antibodies and methods using same
|
|
US7569364B2
(en)
|
2002-12-24 |
2009-08-04 |
Pfizer Inc. |
Anti-NGF antibodies and methods using same
|
|
US9498530B2
(en)
|
2002-12-24 |
2016-11-22 |
Rinat Neuroscience Corp. |
Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
|
|
WO2004065560A2
(en)
|
2003-01-18 |
2004-08-05 |
Rinat Neuroscience Corp. |
Methods of screening for modulators of nerve growth factor
|
|
US7575893B2
(en)
|
2003-01-23 |
2009-08-18 |
Genentech, Inc. |
Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture
|
|
KR20050111598A
(ko)
|
2003-02-19 |
2005-11-25 |
리나트 뉴로사이언스 코퍼레이션 |
신경 성장 인자 길항제 및 nsaid를 투여함으로써통증을 치료하는 방법 및 그것을 함유하는 조성물
|
|
US8545830B2
(en)
|
2003-03-24 |
2013-10-01 |
University Of Tennessee Research Foundation |
Multi-functional polymeric materials and their uses
|
|
US20060193825A1
(en)
|
2003-04-29 |
2006-08-31 |
Praecis Phamaceuticals, Inc. |
Pharmaceutical formulations for sustained drug delivery
|
|
BRPI0410377A
(pt)
|
2003-05-16 |
2006-06-13 |
Blue Membranes Gmbh |
implantes medicinais revestidos bio-compatìveis
|
|
US20070041972A1
(en)
|
2003-05-30 |
2007-02-22 |
Alexion Pharmaceuticals, Inc. |
Antibodies and fusion proteins that include engineered constant regions
|
|
EP1646426A2
(en)
|
2003-07-10 |
2006-04-19 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Appl proteins as rab5 effectors
|
|
DK1648509T3
(da)
|
2003-07-15 |
2013-01-07 |
Amgen Inc |
Humane anti-NGF-neutraliserende antistoffer som selektive NGF-pathway-inhibitorer
|
|
US20050027110A1
(en)
|
2003-07-24 |
2005-02-03 |
Michael Russell |
Drug delivery in the nervous system
|
|
EP1500399A1
(en)
|
2003-07-24 |
2005-01-26 |
Institut Pasteur |
Active or passive immunization against proapoptotic neurotrophins for the treatment or prevention of neurodegenerative deseases
|
|
US7205387B2
(en)
|
2003-08-28 |
2007-04-17 |
Agency For Science, Technology And Research |
Recombinant polypeptide useful for neurotrophin receptor mediated gene delivery and as neurotrophin agonist
|
|
US20050085417A1
(en)
|
2003-10-16 |
2005-04-21 |
Thomas Jefferson University |
Compounds and methods for diagnostic imaging and therapy
|
|
US7846891B2
(en)
|
2003-10-17 |
2010-12-07 |
Massachusetts Institute Of Technology |
Self-assembling peptides for regeneration and repair of neural tissue
|
|
EP2330201B1
(en)
|
2003-10-22 |
2017-04-05 |
Keck Graduate Institute |
Methods of synthesizing heteromultimeric polypeptides in yeast using a haploid mating strategy
|
|
US8133733B2
(en)
|
2003-10-24 |
2012-03-13 |
Gencia Corporation |
Nonviral vectors for delivering polynucleotides to target tissues
|
|
US20090123468A1
(en)
|
2003-10-24 |
2009-05-14 |
Gencia Corporation |
Transducible polypeptides for modifying metabolism
|
|
WO2005051423A2
(en)
|
2003-11-30 |
2005-06-09 |
Yeda Research And Development Co. Ltd |
Methods and agents for immune modulation and methods for identifying immune modulators
|
|
US20050123526A1
(en)
|
2003-12-01 |
2005-06-09 |
Medtronic Inc. |
Administration of growth factors for neurogenesis and gliagenesis
|
|
US8093205B2
(en)
|
2003-12-01 |
2012-01-10 |
Medtronic, Inc. |
Method for treating a stroke by implanting a first therapy delivery element in the CNS and a second therapy delivery element in a damaged tissue of the CNS to promote neurogenesis
|
|
WO2005059515A2
(en)
|
2003-12-16 |
2005-06-30 |
Children's Medical Center Corporation |
Method for treating neurological disorders
|
|
ATE554107T1
(de)
|
2003-12-19 |
2012-05-15 |
Genentech Inc |
Als therapeutika geeignete monovalente antikörperfragmente
|
|
DE10360483B4
(de)
|
2003-12-22 |
2007-11-15 |
Scil Proteins Gmbh |
Expressionsvektor und dessen Verwendung
|
|
ITRM20030601A1
(it)
|
2003-12-24 |
2005-06-25 |
Lay Line Genomics Spa |
Metodo per l'umanizzazione di anticorpi e anticorpi umanizzati con esso ottenuti.
|
|
WO2005065721A2
(en)
|
2003-12-30 |
2005-07-21 |
Board Of Regents, The University Of Texas System |
Use of an anti-inflammatory compound for the reduction of inflammation secondary to the administration of a lipid-nucleic acid complex
|
|
US8883160B2
(en)
|
2004-02-13 |
2014-11-11 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
|
US8562988B2
(en)
|
2005-10-19 |
2013-10-22 |
Ibc Pharmaceuticals, Inc. |
Strategies for improved cancer vaccines
|
|
US20050260711A1
(en)
|
2004-03-30 |
2005-11-24 |
Deepshikha Datta |
Modulating pH-sensitive binding using non-natural amino acids
|
|
JP5301152B2
(ja)
|
2004-04-07 |
2013-09-25 |
ライナット ニューロサイエンス コーポレイション |
神経成長因子アンタゴニストを投与することによって骨癌の疼痛を処置するための方法
|
|
WO2005100589A2
(en)
|
2004-04-19 |
2005-10-27 |
Hankins William D |
Kinetic process for the detection, diagnosis, processing, and monitoring of clonal cell populations
|
|
ITRM20040212A1
(it)
|
2004-04-30 |
2004-07-30 |
Lay Line Genomics Spa |
Animale transgenico non umano come modello per malattie neurodegenerative e per la loro diagnosi precoce.
|
|
CN1997382A
(zh)
|
2004-05-05 |
2007-07-11 |
梅里麦克制药股份有限公司 |
调节生物活性的双特异性结合剂
|
|
EA012622B1
(ru)
|
2004-06-01 |
2009-10-30 |
Домэнтис Лимитед |
Биспецифичные гибридные антитела с увеличенным периодом полувыведения из сыворотки
|
|
JP2008501725A
(ja)
|
2004-06-10 |
2008-01-24 |
ザ ウォルター アンド エリザ ホール インスティテュート オブ メディカル リサーチ |
グリカンに特異的な受容体として機能するインテグリンを介したグリコシルホスファチジルイノシトールグリカンシグナル伝達
|
|
US7740861B2
(en)
|
2004-06-16 |
2010-06-22 |
University Of Massachusetts |
Drug delivery product and methods
|
|
WO2006001023A2
(en)
|
2004-06-28 |
2006-01-05 |
Yeda Research And Development Co. Ltd |
Chimeric proteins and uses thereof
|
|
US7514088B2
(en)
|
2005-03-15 |
2009-04-07 |
Allergan, Inc. |
Multivalent Clostridial toxin derivatives and methods of their use
|
|
ME00226B
(me)
|
2004-07-15 |
2011-02-10 |
Medarex Llc |
Humana anti-ngf neutrališuća antitijela kao selektivni inhibitori ngf signalne kaskade
|
|
AU2005278136A1
(en)
|
2004-08-02 |
2006-03-02 |
Children's Medical Center Corporation |
Platelet biomarkers for cancer
|
|
RU2398777C2
(ru)
|
2004-08-05 |
2010-09-10 |
Дженентек, Инк. |
ГУМАНИЗИРОВАННЫЕ АНТАГОНИСТЫ, НАПРАВЛЕННЫЕ ПРОТИВ c-met
|
|
US20060068469A1
(en)
|
2004-08-17 |
2006-03-30 |
Research Development Foundation |
Bacterial vector systems
|
|
KR100876771B1
(ko)
|
2004-08-17 |
2009-01-07 |
삼성전자주식회사 |
무선 통신 시스템에서 제어 정보 압축 방법과 스캐닝 정보 송수신 방법 및 장치
|
|
WO2006026780A1
(en)
|
2004-09-01 |
2006-03-09 |
Allergan, Inc. |
Degradable clostridial toxins
|
|
AU2005284835A1
(en)
|
2004-09-14 |
2006-03-23 |
Novartis Vaccines And Diagnostics Inc. |
Imidazoquinoline compounds
|
|
MX2007003320A
(es)
|
2004-09-24 |
2007-05-18 |
Amgen Inc |
Moleculas fc modificadas.
|
|
US7629325B2
(en)
|
2004-10-11 |
2009-12-08 |
Technion Research & Development Foundation Ltd. |
Human Sef isoforms and methods of using same for cancer diagnosis and gene therapy
|
|
WO2006047593A2
(en)
|
2004-10-22 |
2006-05-04 |
University Of South Florida |
Method of potentiating inflammatory and immune modulation for cell and drug therapy
|
|
EP1815865A4
(en)
|
2004-11-08 |
2010-08-25 |
Ono Pharmaceutical Co |
THERAPEUTIC AGENT AGAINST DIABETES WITH A PROTEASE-INHIBITING COMPOUND
|
|
US8257696B2
(en)
|
2004-11-19 |
2012-09-04 |
University Of Florida Research Foundation, Inc. |
Indefinite culture of human adult glia without immortalization and therapeutic uses thereof
|
|
WO2006074399A2
(en)
|
2005-01-05 |
2006-07-13 |
Biogen Idec Ma Inc. |
Multispecific binding molecules comprising connecting peptides
|
|
PL1844337T3
(pl)
|
2005-01-24 |
2013-12-31 |
Pepscan Systems Bv |
Związki wiążące, związki immunogenne i peptydomimetyki
|
|
BRPI0606933B8
(pt)
|
2005-01-24 |
2021-05-25 |
Cambridge Antibody Tech Limited |
membro de ligação específico isolado para fator de crescimento de nervos, molécula de anticorpo isolado, composição e uso de um membro de ligação específico
|
|
JP5735194B2
(ja)
|
2005-01-25 |
2015-06-17 |
セル セラピューティクス インコーポレーテッド |
改善された生体内半減期を有する生物学的に活性なタンパク質
|
|
WO2006084173A1
(en)
|
2005-02-04 |
2006-08-10 |
The Johns Hopkins University |
Electroporation gene therapy gun system
|
|
US20060182724A1
(en)
|
2005-02-15 |
2006-08-17 |
Riordan Neil H |
Method for expansion of stem cells
|
|
WO2006101634A1
(en)
|
2005-02-17 |
2006-09-28 |
The Regents Of The University Of California |
Müller cell specific gene therapy
|
|
US20090136505A1
(en)
|
2005-02-23 |
2009-05-28 |
Johanna Bentz |
Intranasal Administration of Active Agents to the Central Nervous System
|
|
BRPI0607486B8
(pt)
|
2005-03-03 |
2021-05-25 |
Immunomedics Inc |
anticorpo humanizado l243 contra hla-dr presente nas células hladr+,composição farmacêutica, kit e uso dos referidos anticorpos.
|
|
US8658778B2
(en)
|
2005-03-09 |
2014-02-25 |
Board Of Regents, The University Of Texas System |
hTMC promoter and vectors for the tumor-selective and high-efficient expression of cancer therapeutic genes
|
|
WO2006102542A2
(en)
|
2005-03-23 |
2006-09-28 |
Bio-Rad Laboratories, Inc. |
Diverse chemical libraries bound to small particles with paramagnetic properties
|
|
US8349332B2
(en)
|
2005-04-06 |
2013-01-08 |
Ibc Pharmaceuticals, Inc. |
Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases
|
|
RU2007143302A
(ru)
|
2005-04-22 |
2009-05-27 |
Дженентек, Инк. (Us) |
Способ лечения деменции или болезни альцгеймера антителами к cd20
|
|
KR20080026562A
(ko)
|
2005-06-02 |
2008-03-25 |
갤럭시 바이오테크, 엘엘씨 |
항체를 이용한 뇌종양 치료 방법
|
|
KR20080032070A
(ko)
|
2005-06-06 |
2008-04-14 |
와이어쓰 |
항-TrkB 모노클로날 항체 및 이의 용도
|
|
ITRM20050290A1
(it)
|
2005-06-07 |
2006-12-08 |
Lay Line Genomics Spa |
Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato.
|
|
DE602005012812D1
(de)
|
2005-06-13 |
2009-04-02 |
Primm Srl |
Heterodimere Peptide mit NGF Aktivität und deren Verwendung zur Behandlung von neurodegenerativen Krankheiten
|
|
ES2776657T3
(es)
|
2005-06-14 |
2020-07-31 |
Amgen Inc |
Formulaciones de proteínas autotamponantes
|
|
WO2006138343A2
(en)
|
2005-06-14 |
2006-12-28 |
Raptor Pharmaceutical Inc. |
Compositions comprising receptor - associated protein (rap) variants specific for lrp2 and uses thereof
|
|
ITRM20050332A1
(it)
|
2005-06-24 |
2006-12-25 |
Lay Line Genomics Spa |
Uso di molecole in grado di bloccare l'attivita' di trka per potenziare gli effetti di analgesici oppiacei sul dolore.
|
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
|
EP1945668A4
(en)
|
2005-08-15 |
2009-07-22 |
Arana Therapeutics Ltd |
SYNTHETIC ANTIBODIES WITH FRAMEWORK REGIONS OF NEUWELTPRIMATEN
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
EP2267030A1
(en)
|
2005-08-25 |
2010-12-29 |
Repair Technologies, Inc. |
Devices, compositions and methods for the protection and repair of cells and tissues
|
|
WO2007035906A2
(en)
|
2005-09-21 |
2007-03-29 |
The Regents Of The University Of California |
Systems and methods for imaging-treatment of pain
|
|
US8142781B2
(en)
|
2005-10-07 |
2012-03-27 |
Armagen Technologies, Inc. |
Fusion proteins for blood-brain barrier delivery
|
|
CA2628843A1
(en)
|
2005-11-07 |
2007-05-10 |
Copenhagen University |
Neurotrophin-derived peptide sequences
|
|
CN101573441A
(zh)
|
2005-12-08 |
2009-11-04 |
路易斯维尔大学研究基金会有限公司 |
非常小的胚胎样(vsel)干细胞及分离和利用其的方法
|
|
US20070243132A1
(en)
|
2005-12-22 |
2007-10-18 |
Apollo Life Sciences Limited |
Transdermal delivery of pharmaceutical agents
|
|
US9265814B2
(en)
|
2005-12-30 |
2016-02-23 |
Neurotech Usa, Inc. |
Micronized device for the delivery of biologically active molecules and methods of use thereof
|
|
US7342146B2
(en)
|
2006-01-11 |
2008-03-11 |
Industrial Technology Research Institute |
Neurodegenerative non-human transgenic mammal expressing TrkA fusion protein
|
|
KR100784485B1
(ko)
|
2006-01-18 |
2007-12-11 |
한국과학기술연구원 |
생분해성 온도 감응성 폴리포스파젠계 하이드로젤, 그의제조방법 및 그의 용도
|
|
US7520888B2
(en)
|
2006-02-14 |
2009-04-21 |
Warsaw Orthopedic, Inc. |
Treatment of the vertebral column
|
|
DK1988910T3
(en)
|
2006-02-28 |
2018-01-22 |
Kodiak Sciences Inc |
ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE-CONTAINING POLYMER CONJUGATES AND PREPARATION thereof
|
|
CA2647632C
(en)
|
2006-03-27 |
2017-06-27 |
University Of Maryland Biotechnology Institute |
Glycoprotein synthesis and remodeling by enzymatic transglycosylation
|
|
KR100746962B1
(ko)
|
2006-04-04 |
2007-08-07 |
한국과학기술연구원 |
온도 감응성 포스파젠계 고분자-생리 활성 물질 복합체,그의 제조방법 및 그의 용도
|
|
ES2618787T5
(es)
|
2006-04-25 |
2022-10-21 |
Univ California |
Administración de factores de crecimiento para el tratamiento de trastornos del SNC
|
|
CA2651285C
(en)
|
2006-05-15 |
2014-08-19 |
Immunomedics, Inc. |
Methods and compositions for treatment of human immunodeficiency virus infection with conjugated antibodies or antibody fragments
|
|
MX2008014692A
(es)
|
2006-05-19 |
2009-08-18 |
Alder Biopharmaceuticals Inc |
Metodo de cultivo para obtener una poblacion clonal de celulas b especificas de antigeno.
|
|
US8623610B2
(en)
|
2006-05-22 |
2014-01-07 |
California Institute Of Technology |
Chondroitin sulfate binding proteins and modulators thereof
|
|
EP2029726A4
(en)
|
2006-06-09 |
2010-07-28 |
Univ Miami |
ASSESSMENT OF CELL COMPOSITION AND FRACTIVITY AND USES THEREOF
|
|
US8475788B2
(en)
|
2006-06-14 |
2013-07-02 |
Stemnion, Inc. |
Methods of treating spinal cord injury and minimizing scarring
|
|
TW200817512A
(en)
|
2006-07-07 |
2008-04-16 |
Kirin Pharma Kk |
Human artificial chromosome (hac) vector, and human cell pharmaceutical comprising human artificial chromosome (hac) vector
|
|
US20080132427A1
(en)
|
2006-07-21 |
2008-06-05 |
Yao Zhuang |
Cell systems and methods for detecting proliferation acitvity
|
|
DE602006013809D1
(de)
|
2006-07-24 |
2010-06-02 |
Facultad De Medicina Universid |
Antikörper, Antikörperfragmente und scFv die an posttranslational modifizierte Neurotrophine binden
|
|
EP2068866A4
(en)
|
2006-07-24 |
2010-04-07 |
Biogen Idec Inc |
METHODS FOR PROMOTING MYELINIZATION, NEURONAL SURVIVAL AND DIFFERENTIATION OF OLIGODENDROCYTES BY ADMINISTERING SP35 OR TRKA ANTAGONISTS
|
|
US8168169B2
(en)
|
2006-08-09 |
2012-05-01 |
Mclean Hospital Corporation |
Methods and compositions for the treatment of medical disorders
|
|
WO2008024499A2
(en)
|
2006-08-25 |
2008-02-28 |
Duke University |
Methods for in vivo identification of endogenous mrna targets of micrornas
|
|
US20090004742A1
(en)
|
2006-11-01 |
2009-01-01 |
Duke University |
Selection of antigen-specific t cells
|
|
GB0622688D0
(en)
|
2006-11-14 |
2006-12-27 |
Diosamine Dev Corp |
Novel compounds
|
|
CN101657212B
(zh)
|
2006-12-05 |
2014-03-19 |
皇家学习促进会/麦吉尔大学 |
Trk受体调节剂的使用方法
|
|
US20080139790A1
(en)
|
2006-12-08 |
2008-06-12 |
Jennings Philip A |
Chimeric antibodies
|
|
HUE048781T2
(hu)
|
2006-12-21 |
2020-08-28 |
H Lundbeck As |
Proneurotrofinok aktivitásának modulációja
|
|
JP2010514700A
(ja)
|
2006-12-22 |
2010-05-06 |
ジェネンテック, インコーポレイテッド |
Dr6アンタゴニスト及び神経障害の治療におけるその使用法
|
|
US8183219B2
(en)
|
2007-01-03 |
2012-05-22 |
Medtronic, Inc. |
Therapeuting compositions comprising an RNAi agent and a neurotrophic factor and methods of use thereof
|
|
US20100009997A1
(en)
|
2007-01-12 |
2010-01-14 |
Biomarin Pharmaceutical Inc. |
Method of treating a metabolic or neuropsychiarty disorder with a bh4 derivative prodrug
|
|
WO2008097817A2
(en)
|
2007-02-02 |
2008-08-14 |
Baylor Research Institute |
Multivariable antigens complexed with targeting humanized monoclonal antibody
|
|
KR20090114430A
(ko)
|
2007-02-02 |
2009-11-03 |
베일러 리서치 인스티튜트 |
항원-제시 세포 상에서 발현된 dcir에 대한 항원 표적화에 기초한 백신
|
|
US20080233088A1
(en)
|
2007-02-16 |
2008-09-25 |
Varian Medical Systems Technologies, Inc. |
Preparative regimen for engraftment, growth and differentiation of non-hematopoeitic cells in vivo after transplantation
|
|
EP2126087A4
(en)
|
2007-02-20 |
2010-10-27 |
Anaptysbio Inc |
METHODS FOR PRODUCING PHARMACOTHEQUES, AND USES THEREOF
|
|
EP2129773B1
(en)
|
2007-02-23 |
2013-02-13 |
Baylor Research Institute |
Therapeutic applications of activation of human antigen-presenting cells through dectin-1
|
|
KR20090118981A
(ko)
|
2007-02-23 |
2009-11-18 |
베일러 리서치 인스티튜트 |
Clec-6을 통한 사람 항원제시세포의 활성화
|
|
US20110268776A1
(en)
|
2007-04-25 |
2011-11-03 |
Schapira Jay N |
Programmed-release, nanostructured biological construct for stimulating cellular engraftment for tissue regeneration
|
|
WO2008144753A2
(en)
|
2007-05-21 |
2008-11-27 |
Alder Biopharmaceuticals, Inc. |
Antibodies to tnf alpha and use thereof
|
|
KR20100028571A
(ko)
|
2007-05-21 |
2010-03-12 |
앨더 바이오파마슈티컬즈, 인코포레이티드 |
신규한 래빗 항체 인간화 방법 및 인간화된 래빗 항체
|
|
CN105001332B
(zh)
|
2007-05-21 |
2018-12-04 |
奥尔德生物控股有限责任公司 |
针对il-6的抗体及其用途
|
|
JP5591691B2
(ja)
|
2007-05-22 |
2014-09-17 |
アムジエン・インコーポレーテツド |
生物活性を有する融合タンパク質を作製するための組成物及び方法
|
|
PE20090329A1
(es)
|
2007-05-30 |
2009-03-27 |
Abbott Lab |
Anticuerpos humanizados contra el globulomero ab(20-42) y sus usos
|
|
US20090232801A1
(en)
|
2007-05-30 |
2009-09-17 |
Abbot Laboratories |
Humanized Antibodies Which Bind To AB (1-42) Globulomer And Uses Thereof
|
|
EP2666787B1
(en)
|
2007-05-31 |
2022-02-09 |
Genmab A/S |
STABLE IgG4 ANTIBODIES
|
|
KR100968591B1
(ko)
|
2007-06-14 |
2010-07-08 |
한국과학기술연구원 |
약물전달용 폴리포스파젠계 하이드로젤, 그의 제조방법 및그의 용도
|
|
US20080318314A1
(en)
|
2007-06-20 |
2008-12-25 |
Valentin Fulga |
Production from blood of cells of neural lineage
|
|
WO2009003145A1
(en)
|
2007-06-26 |
2008-12-31 |
University Of Miami |
Antibody-endostatin fusion protein and its variants
|
|
PL2188302T3
(pl)
|
2007-07-09 |
2018-04-30 |
Genentech, Inc. |
Zapobieganie redukcji wiązań disiarczkowych podczas rekombinacyjnego wytwarzania polipeptydów
|
|
US8309088B2
(en)
|
2007-08-10 |
2012-11-13 |
Regeneron Pharmaceuticals, Inc. |
Method of treating osteoarthritis with an antibody to NGF
|
|
BRPI0815370B8
(pt)
|
2007-08-10 |
2021-05-25 |
Regeneron Pharma |
anticorpos humanos de alta afinidade contra o fator de crescimento neural humano e seu uso, molécula de ácido nucleico, vetor de expressão, método para produção de um anticorpo anti-ngf humano e composiçao farmacêutica
|
|
WO2009032148A1
(en)
|
2007-08-29 |
2009-03-12 |
Tufts University |
Methods of making and using a cell penetrating peptide for enhanced delivery of nucleic acids, proteins, drugs, and adenovirus to tissues and cells, and compositions and kits
|
|
CA2700701C
(en)
|
2007-09-26 |
2020-12-29 |
Chugai Seiyaku Kabushiki Kaisha |
Method of modifying isoelectric point of antibody via amino acid substitution in cdr
|
|
US20110034383A1
(en)
|
2007-10-15 |
2011-02-10 |
Institut Pasteur |
Cxcl12 gamma a chemokine and uses thereof
|
|
EP2219458B1
(en)
|
2007-11-08 |
2015-07-15 |
Cytimmune Sciences, Inc. |
Compositions and methods for generating antibodies
|
|
EP2220125A4
(en)
|
2007-11-13 |
2010-12-29 |
Sapphire Energy Inc |
PRODUCTION OF FC HYBRID POLYPEPTIDES IN EUKARYOTIC ALGAE
|
|
EA201000785A1
(ru)
|
2007-12-13 |
2011-02-28 |
Глаксо Груп Лимитед |
Композиции для доставки в легкие
|
|
CN106977601A
(zh)
|
2007-12-17 |
2017-07-25 |
辉瑞有限公司 |
间质性膀胱炎的治疗
|
|
WO2009088805A2
(en)
|
2008-01-03 |
2009-07-16 |
The Scripps Research Institute |
Antibody targeting through a modular recognition domain
|
|
EP2292089A1
(en)
|
2008-01-11 |
2011-03-09 |
Astellas Pharma Inc. |
Model animal having both pain in testis or testis-related discomfort actions and frequent urination
|
|
EP2249856B1
(en)
|
2008-01-30 |
2013-11-06 |
Baylor College Of Medicine |
Peptides that target dorsal root ganglion neurons
|
|
PL2252633T3
(pl)
|
2008-02-04 |
2014-02-28 |
Lay Line Genomics Spa |
Przeciwciała anty-TrkA i ich pochodne
|
|
CN102027123B
(zh)
|
2008-03-14 |
2016-03-16 |
人体酶有限公司 |
使用人细胞表达系统重组产生可靠的人蛋白质
|
|
EP2254886B1
(en)
|
2008-03-28 |
2016-05-25 |
Nerviano Medical Sciences S.r.l. |
3,4-dihydro-2h-pyrazino[1,2-a]indol-1-one derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
|
|
KR101614558B1
(ko)
|
2008-04-27 |
2016-04-22 |
하. 룬드벡 아크티에셀스카브 |
인간 소르틸린의 결정 구조 및 소르틸린에 대한 리간드를 확인하기 위한 이의 용도
|
|
SG191639A1
(en)
|
2008-06-03 |
2013-07-31 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
EP2297208A4
(en)
|
2008-06-03 |
2012-07-11 |
Abbott Lab |
DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND ITS USES
|
|
WO2009150623A1
(en)
|
2008-06-13 |
2009-12-17 |
Pfizer Inc |
Treatment of chronic prostatitis
|
|
EP2307042B1
(en)
|
2008-06-25 |
2014-03-26 |
H. Lundbeck A/S |
Modulation of the trpv : vps10p-domain receptor system for the treatment of pain
|
|
KR20110031369A
(ko)
|
2008-07-08 |
2011-03-25 |
아보트 러보러터리즈 |
프로스타글란딘 e2 이원 가변 도메인 면역글로불린 및 이의 용도
|
|
CN101633694B
(zh)
|
2008-07-24 |
2012-08-29 |
厦门北大之路生物工程有限公司 |
抗鼠神经生长因子(ngf)的多克隆抗体的制备方法及其应用
|
|
CA2734265C
(en)
|
2008-08-20 |
2017-12-19 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (dnl) vaccines for cancer therapy
|
|
JP5642683B2
(ja)
|
2008-09-19 |
2014-12-17 |
ファイザー・インク |
安定な液体抗体配合物
|
|
US8025879B2
(en)
|
2008-09-26 |
2011-09-27 |
Eureka Therapeutics, Inc. |
Modified glycoproteins and uses thereof
|
|
WO2010040271A1
(en)
|
2008-10-07 |
2010-04-15 |
Tuo Jin |
Phase-transition polymeric microneedles
|
|
US9101645B2
(en)
|
2008-10-22 |
2015-08-11 |
Genentech, Inc. |
Modulation of axon degeneration
|
|
US20100104652A1
(en)
|
2008-10-27 |
2010-04-29 |
University Of Arkansas |
Use of advanced nanomaterials for increasing sepecific cell functions
|
|
CN104357381A
(zh)
|
2008-10-31 |
2015-02-18 |
辛西斯有限责任公司 |
用于活化干细胞的方法和装置
|
|
EP3153524B1
(en)
|
2008-12-03 |
2025-04-23 |
Genmab A/S |
Antibody variants having modifications in the constant region
|
|
FR2944448B1
(fr)
|
2008-12-23 |
2012-01-13 |
Adocia |
Composition pharmaceutique stable comprenant au moins un anticorps monodonal et au moins un polysacharide amphiphile comprenant des substituants derives d'alcools hydrofobes ou d'amines hydrophobes.
|
|
CA2745462C
(en)
|
2008-12-31 |
2014-07-15 |
Kci Licensing, Inc. |
Tissue roll scaffolds
|
|
CN102361971A
(zh)
|
2009-01-23 |
2012-02-22 |
Ns基因公司 |
改善的细胞系以及在胶囊化细胞生物递送中的用途
|
|
AR076650A1
(es)
|
2009-05-04 |
2011-06-29 |
Pangenetics 110 B V |
Anticuerpos contra el factor de crecimiento nervioso (ngf) con una estabilidad in vivo mejorada
|
|
BR112012000025A2
(pt)
|
2009-07-02 |
2015-09-08 |
Glaxo Group Ltd |
polipeptídos e processo de tratamento.
|
|
US20110033463A1
(en)
|
2009-08-06 |
2011-02-10 |
Medtronic, Inc. |
Apheresis, administration of agent, or combination thereof
|
|
ES2793348T5
(en)
|
2009-08-11 |
2025-04-11 |
Hoffmann La Roche |
Production of proteins in glutamine-free cell culture media
|
|
JO3246B1
(ar)
|
2009-09-09 |
2018-03-08 |
Regeneron Pharma |
اجسام مضادة بشرية ذات ألفة تفاعل عالية مع مستقبل 2 المفعل بالبروتين البشري
|
|
CN102482701B
(zh)
|
2009-09-16 |
2015-05-13 |
免疫医疗公司 |
I类抗-cea抗体及其使用
|
|
US9155722B2
(en)
|
2009-09-18 |
2015-10-13 |
Protherics Salt Lake City, Inc. |
Reconstitutable reverse thermal gelling polymers
|
|
US8753621B2
(en)
|
2009-09-18 |
2014-06-17 |
Protherics Salt Lake City, Inc. |
BAB triblock polymers having improved release characteristics
|
|
TW201119676A
(en)
|
2009-10-15 |
2011-06-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
WO2011085354A1
(en)
|
2010-01-11 |
2011-07-14 |
Center For Molecular Medicine And Immunology |
Enhanced cytotoxicity of anti-cd74 and anti-hla-dr antibodies with interferon-gamma
|
|
US8975233B2
(en)
|
2010-01-26 |
2015-03-10 |
Northwind Medical, Inc. |
Methods for renal denervation
|
|
US20110250206A1
(en)
|
2010-02-11 |
2011-10-13 |
Axtell Robert C |
Markers for determination of patient responsiveness
|
|
CA2790699A1
(en)
|
2010-03-17 |
2011-09-22 |
Abbott Research B.V. |
Anti-nerve growth factor (ngf) antibody compositions
|
|
AU2011235328A1
(en)
|
2010-04-01 |
2012-09-27 |
Immunomedics, Inc. |
Antibody-based depletion of antigen-presenting cells and dendritic cells
|
|
JP2013523153A
(ja)
|
2010-04-07 |
2013-06-17 |
アッヴィ・インコーポレイテッド |
TNF−α結合タンパク質
|
|
AU2011240677B2
(en)
|
2010-04-12 |
2015-05-14 |
Somalogic Operating Co., Inc. |
5-position modified pyrimidines and their use
|
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
JOP20190250A1
(ar)
|
2010-07-14 |
2017-06-16 |
Regeneron Pharma |
صيغ مستقرة تحتوي على الأجسام المضادة لمضاد عامل نمو الأعصاب
|
|
JP6121903B2
(ja)
|
2010-08-19 |
2017-04-26 |
ゾエティス・ベルジャム・エス・アー |
抗ngf抗体およびその使用
|
|
BR112013004581A2
(pt)
|
2010-08-26 |
2017-06-27 |
Abbvie Inc |
imunoglobulinas de domínio variável dual e seus usos
|
|
US9539324B2
(en)
|
2010-12-01 |
2017-01-10 |
Alderbio Holdings, Llc |
Methods of preventing inflammation and treating pain using anti-NGF compositions
|
|
US9067988B2
(en)
|
2010-12-01 |
2015-06-30 |
Alderbio Holdings Llc |
Methods of preventing or treating pain using anti-NGF antibodies
|
|
MX359070B
(es)
|
2010-12-01 |
2018-09-13 |
Alderbio Holdings Llc |
Composiciones anti-ngf y uso de las mismas.
|
|
US9078878B2
(en)
|
2010-12-01 |
2015-07-14 |
Alderbio Holdings Llc |
Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
|
|
US9884909B2
(en)
|
2010-12-01 |
2018-02-06 |
Alderbio Holdings Llc |
Anti-NGF compositions and use thereof
|
|
US20120195900A1
(en)
|
2010-12-22 |
2012-08-02 |
Abbott Laboratories |
Tri-variable domain binding proteins and uses thereof
|
|
US20120201746A1
(en)
|
2010-12-22 |
2012-08-09 |
Abbott Laboratories |
Half immunoglobulin binding proteins and uses thereof
|
|
US8668886B2
(en)
|
2011-04-24 |
2014-03-11 |
Therapeutic Proteins International, LLC |
Separative bioreactor
|
|
WO2012153123A1
(en)
|
2011-05-06 |
2012-11-15 |
Nvip Pty Ltd |
Anti-nerve growth factor antibodies and methods of preparing and using the same
|
|
KR101783929B1
(ko)
|
2011-05-06 |
2017-10-11 |
넥스베트 오스트레일리아 피티와이 리미티드 |
항신경성 성장 인자 항체 및 그의 제조방법과 이용방법
|
|
CA2842492A1
(en)
|
2011-08-05 |
2013-02-14 |
Bioasis Technologies, Inc. |
P97 fragments with transfer activity
|
|
WO2013022083A1
(ja)
|
2011-08-11 |
2013-02-14 |
アステラス製薬株式会社 |
新規抗ヒトngf抗体
|
|
US8926978B2
(en)
|
2011-10-25 |
2015-01-06 |
Anaptysbio, Inc. |
Antibodies directed against nerve growth factor (NGF)
|
|
US20130344064A1
(en)
|
2012-06-08 |
2013-12-26 |
Glenmark Pharmaceuticals S.A. |
Anti-trka antibodies with enhanced inhibitory properties and derivatives thereof
|
|
EP2674439B1
(en)
|
2012-06-13 |
2017-02-01 |
Rottapharm Biotech S.r.l. |
Anti-TrkA antibodies, derivatives and uses thereof
|
|
US9682143B2
(en)
|
2012-08-14 |
2017-06-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|