MX2008014692A - Metodo de cultivo para obtener una poblacion clonal de celulas b especificas de antigeno. - Google Patents
Metodo de cultivo para obtener una poblacion clonal de celulas b especificas de antigeno.Info
- Publication number
- MX2008014692A MX2008014692A MX2008014692A MX2008014692A MX2008014692A MX 2008014692 A MX2008014692 A MX 2008014692A MX 2008014692 A MX2008014692 A MX 2008014692A MX 2008014692 A MX2008014692 A MX 2008014692A MX 2008014692 A MX2008014692 A MX 2008014692A
- Authority
- MX
- Mexico
- Prior art keywords
- antigen
- cells
- obtaining
- specific
- culture method
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 238000012136 culture method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/248—IL-6
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0635—B lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
Abstract
La presente invención se relaciona a métodos de aislamiento de células específicas de antígeno y producción de anticuerpos de las mismas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80141206P | 2006-05-19 | 2006-05-19 | |
PCT/US2007/011980 WO2008045140A1 (en) | 2006-05-19 | 2007-05-21 | Culture method for obtaining a clonal population of antigen-specific b cells |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2008014692A true MX2008014692A (es) | 2009-08-18 |
Family
ID=39283142
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2008014692A MX2008014692A (es) | 2006-05-19 | 2007-05-21 | Metodo de cultivo para obtener una poblacion clonal de celulas b especificas de antigeno. |
Country Status (12)
Country | Link |
---|---|
US (3) | US20070269868A1 (es) |
EP (1) | EP2021463B1 (es) |
JP (1) | JP5607357B2 (es) |
CN (1) | CN101600793B (es) |
AU (1) | AU2007307324B2 (es) |
CA (1) | CA2652392C (es) |
DK (1) | DK2021463T3 (es) |
IL (1) | IL195285A (es) |
MX (1) | MX2008014692A (es) |
NO (1) | NO20084835L (es) |
NZ (1) | NZ572807A (es) |
WO (1) | WO2008045140A1 (es) |
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US7906117B2 (en) | 2007-05-21 | 2011-03-15 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever |
JP5833823B2 (ja) | 2007-05-21 | 2015-12-16 | アルダーバイオ・ホールディングズ・エルエルシー | Il−6に対する抗体およびその使用 |
US8178101B2 (en) | 2007-05-21 | 2012-05-15 | Alderbio Holdings Inc. | Use of anti-IL-6 antibodies having specific binding properties to treat cachexia |
US8062864B2 (en) | 2007-05-21 | 2011-11-22 | Alderbio Holdings Llc | Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies |
US8252286B2 (en) | 2007-05-21 | 2012-08-28 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat thrombosis |
US8404235B2 (en) | 2007-05-21 | 2013-03-26 | Alderbio Holdings Llc | Antagonists of IL-6 to raise albumin and/or lower CRP |
US9452227B2 (en) | 2008-11-25 | 2016-09-27 | Alderbio Holdings Llc | Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments |
US8992920B2 (en) | 2008-11-25 | 2015-03-31 | Alderbio Holdings Llc | Anti-IL-6 antibodies for the treatment of arthritis |
EP2361095B1 (en) * | 2008-11-25 | 2017-12-20 | AlderBio Holdings LLC | Antagonists of il-6 to raise albumin and/or lower crp |
US8337847B2 (en) | 2008-11-25 | 2012-12-25 | Alderbio Holdings Llc | Methods of treating anemia using anti-IL-6 antibodies |
US8420089B2 (en) | 2008-11-25 | 2013-04-16 | Alderbio Holdings Llc | Antagonists of IL-6 to raise albumin and/or lower CRP |
US9212223B2 (en) | 2008-11-25 | 2015-12-15 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat thrombosis |
US8323649B2 (en) | 2008-11-25 | 2012-12-04 | Alderbio Holdings Llc | Antibodies to IL-6 and use thereof |
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CA2836799C (en) | 2011-05-20 | 2021-05-18 | Alderbio Holdings Llc | Use of anti-cgrp or anti-cgrp-r antibodies or antibody fragments to treat or prevent chronic and acute forms of diarrhea |
US9708393B2 (en) | 2011-05-20 | 2017-07-18 | Alderbio Holdings Llc | Use of anti-CGRP antibodies and antibody fragments to prevent or inhibit photophobia or light aversion in subjects in need thereof, especially migraine sufferers |
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CN106350485B (zh) * | 2016-08-24 | 2020-02-21 | 杭州百凌生物科技有限公司 | 一种快速高效分离单个抗原特异性b细胞的方法 |
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-
2007
- 2007-05-21 US US11/802,235 patent/US20070269868A1/en not_active Abandoned
- 2007-05-21 WO PCT/US2007/011980 patent/WO2008045140A1/en active Application Filing
- 2007-05-21 MX MX2008014692A patent/MX2008014692A/es active IP Right Grant
- 2007-05-21 CN CN200780027028.2A patent/CN101600793B/zh not_active Expired - Fee Related
- 2007-05-21 CA CA2652392A patent/CA2652392C/en not_active Expired - Fee Related
- 2007-05-21 EP EP07861311.4A patent/EP2021463B1/en not_active Revoked
- 2007-05-21 AU AU2007307324A patent/AU2007307324B2/en not_active Ceased
- 2007-05-21 DK DK07861311.4T patent/DK2021463T3/en active
- 2007-05-21 JP JP2009512060A patent/JP5607357B2/ja not_active Expired - Fee Related
- 2007-05-21 NZ NZ572807A patent/NZ572807A/en not_active IP Right Cessation
-
2008
- 2008-11-13 IL IL195285A patent/IL195285A/en active IP Right Grant
- 2008-11-18 NO NO20084835A patent/NO20084835L/no unknown
-
2011
- 2011-08-08 US US13/204,915 patent/US20120141982A1/en not_active Abandoned
-
2013
- 2013-04-12 US US13/861,518 patent/US20130316353A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2009537176A (ja) | 2009-10-29 |
WO2008045140A1 (en) | 2008-04-17 |
EP2021463A4 (en) | 2009-09-02 |
NZ572807A (en) | 2011-10-28 |
CN101600793B (zh) | 2013-06-26 |
DK2021463T3 (en) | 2017-01-16 |
US20130316353A1 (en) | 2013-11-28 |
CA2652392A1 (en) | 2008-04-17 |
IL195285A (en) | 2012-07-31 |
US20120141982A1 (en) | 2012-06-07 |
EP2021463A1 (en) | 2009-02-11 |
AU2007307324B2 (en) | 2013-08-15 |
US20070269868A1 (en) | 2007-11-22 |
IL195285A0 (en) | 2011-08-01 |
CA2652392C (en) | 2017-10-10 |
NO20084835L (no) | 2009-02-16 |
JP5607357B2 (ja) | 2014-10-15 |
AU2007307324A1 (en) | 2008-04-17 |
EP2021463B1 (en) | 2016-11-23 |
CN101600793A (zh) | 2009-12-09 |
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