DE602006021324D1 - Verfahren zur herstellung stabiler b-lymphozyten - Google Patents
Verfahren zur herstellung stabiler b-lymphozytenInfo
- Publication number
- DE602006021324D1 DE602006021324D1 DE602006021324T DE602006021324T DE602006021324D1 DE 602006021324 D1 DE602006021324 D1 DE 602006021324D1 DE 602006021324 T DE602006021324 T DE 602006021324T DE 602006021324 T DE602006021324 T DE 602006021324T DE 602006021324 D1 DE602006021324 D1 DE 602006021324D1
- Authority
- DE
- Germany
- Prior art keywords
- lymphocytes
- producing stable
- producing
- stable
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71062605P | 2005-08-23 | 2005-08-23 | |
PCT/IB2006/003670 WO2007063415A2 (en) | 2005-08-23 | 2006-08-23 | Methods of producing stable b-lymphocytes |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006021324D1 true DE602006021324D1 (de) | 2011-05-26 |
Family
ID=37968195
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006021324T Active DE602006021324D1 (de) | 2005-08-23 | 2006-08-23 | Verfahren zur herstellung stabiler b-lymphozyten |
Country Status (6)
Country | Link |
---|---|
US (2) | US7807415B2 (de) |
EP (1) | EP1928999B1 (de) |
AT (1) | ATE505535T1 (de) |
CA (1) | CA2619784A1 (de) |
DE (1) | DE602006021324D1 (de) |
WO (2) | WO2007063415A2 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1974020B1 (de) * | 2005-12-16 | 2011-06-15 | Ribovax Biotechnologies SA | Verfahren zur gewinnung immortalisierter antikörpersezernierender zellen |
EP2185718B1 (de) | 2007-08-03 | 2017-10-04 | MUSC Foundation For Research Development | Menschliche monoklonale antikörper und verfahren zu ihrer herstellung |
JP2011510654A (ja) * | 2008-01-28 | 2011-04-07 | トーマス・ジェファーソン・ユニバーシティ | 有用な抗体を発現する雑種細胞の作成方法 |
US8703486B2 (en) | 2008-09-23 | 2014-04-22 | UNIVERSITé LAVAL | Method for polyclonal immunoglobulin G production by human B cells |
US20110129460A1 (en) * | 2009-01-14 | 2011-06-02 | IQ Therapeutics B.V. | Combination Antibodies For The Treatment And Prevention Of Disease Caused By Bacillus Anthracis And Related Bacteria And Their Toxins |
EP3037435B1 (de) | 2009-11-17 | 2019-08-07 | MUSC Foundation for Research Development | Humane monoklonale antikörper gegen menschliches nukleolin |
EP4273232A3 (de) * | 2016-03-30 | 2024-01-03 | F. Hoffmann-La Roche AG | Verfahren zur kultivierung von b-zellen |
CA3031439A1 (en) | 2016-07-18 | 2018-01-25 | President And Fellows Of Harvard College | Human lymphoid tissue-on-chip |
WO2018122147A1 (en) | 2017-01-02 | 2018-07-05 | F. Hoffmann-La Roche Ag | B-cell cultivation method |
CN110621773B (zh) * | 2017-05-19 | 2023-06-09 | 豪夫迈·罗氏有限公司 | 用于产生胸腺细胞上清液的方法 |
EP3717632B1 (de) | 2017-11-30 | 2022-10-26 | F. Hoffmann-La Roche AG | Verfahren zur kultivierung von b-zellen |
WO2021027057A1 (zh) * | 2019-08-15 | 2021-02-18 | 成都冕康生物科技有限公司 | 一种针对ebv病毒抗原的b细胞疫苗及其制备方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5126259A (en) | 1987-12-24 | 1992-06-30 | Takeda Chemical Industries, Ltd. | Human b. lymphoblastoid cell, hybridoma, antibody and production of antibody |
JPH02131574A (ja) * | 1988-06-17 | 1990-05-21 | Biogenex Lab | ミニクローン |
AU3979389A (en) * | 1988-07-15 | 1990-02-05 | United Biotech, Inc. | Enrichment of antigen-specific polyclonal antibodies through selection of immortal hybrid cells |
DK0488470T3 (da) | 1990-11-26 | 1997-12-22 | Akzo Nobel Nv | Fremgangsmåde til fremstilling af antistoffer |
DE4134297A1 (de) * | 1991-10-17 | 1993-04-22 | Behringwerke Ag | Monoclonale antikoerper gegen mycoplasma pneumoniae, diese produzierende hybridome, verfahren zu deren herstellung sowie deren verwendung |
ATE197506T1 (de) | 1992-03-19 | 2000-11-11 | Jackson H M Found Military Med | Breitreaktive opsonische antikörper die mit gemeinsamen antigenen von staphylococcus reagieren |
MX9605088A (es) * | 1994-04-28 | 1997-08-30 | Boehringer Ingelheim Pharma | Metodos para proliferar y diferenciar celulas b y sus usos. |
FI98493C (fi) * | 1994-06-10 | 1997-07-10 | Olavi Kajander | Kasvutekijävalmiste, menetelmä sen valmistamiseksi ja käyttämiseksi ja sitä sisältävä elatusaine |
US7115264B2 (en) * | 2001-11-05 | 2006-10-03 | Inhibitex | Monoclonal antibodies to the fibronectin binding protein and method of use in treating or preventing infections |
US7169903B2 (en) * | 2001-12-21 | 2007-01-30 | Biosynexus Incorporated | Multifunctional monoclonal antibodies directed to peptidoglycan of gram-positive bacteria |
KR20080031001A (ko) * | 2005-06-02 | 2008-04-07 | 아스트라제네카 아베 | Cd20에 대한 항체 및 그의 용도 |
-
2006
- 2006-08-23 US US11/509,364 patent/US7807415B2/en not_active Expired - Fee Related
- 2006-08-23 WO PCT/IB2006/003670 patent/WO2007063415A2/en active Application Filing
- 2006-08-23 EP EP06842246A patent/EP1928999B1/de not_active Not-in-force
- 2006-08-23 US US11/509,365 patent/US20070065919A1/en not_active Abandoned
- 2006-08-23 DE DE602006021324T patent/DE602006021324D1/de active Active
- 2006-08-23 CA CA002619784A patent/CA2619784A1/en not_active Abandoned
- 2006-08-23 WO PCT/IB2006/003513 patent/WO2007049152A2/en active Application Filing
- 2006-08-23 AT AT06842246T patent/ATE505535T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US20070098711A1 (en) | 2007-05-03 |
EP1928999A2 (de) | 2008-06-11 |
WO2007063415A2 (en) | 2007-06-07 |
ATE505535T1 (de) | 2011-04-15 |
CA2619784A1 (en) | 2007-06-07 |
WO2007063415A3 (en) | 2007-11-01 |
WO2007049152A2 (en) | 2007-05-03 |
EP1928999B1 (de) | 2011-04-13 |
WO2007049152A3 (en) | 2007-10-04 |
US20070065919A1 (en) | 2007-03-22 |
US7807415B2 (en) | 2010-10-05 |
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