DE602005012812D1 - Heterodimere Peptide mit NGF Aktivität und deren Verwendung zur Behandlung von neurodegenerativen Krankheiten - Google Patents

Heterodimere Peptide mit NGF Aktivität und deren Verwendung zur Behandlung von neurodegenerativen Krankheiten

Info

Publication number
DE602005012812D1
DE602005012812D1 DE602005012812T DE602005012812T DE602005012812D1 DE 602005012812 D1 DE602005012812 D1 DE 602005012812D1 DE 602005012812 T DE602005012812 T DE 602005012812T DE 602005012812 T DE602005012812 T DE 602005012812T DE 602005012812 D1 DE602005012812 D1 DE 602005012812D1
Authority
DE
Germany
Prior art keywords
treatment
neurodegenerative diseases
loop
ngf
ngf activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005012812T
Other languages
English (en)
Inventor
Luigi Vitagliano
Laura Zaccaro
Giancarlo Morelli
Enzo Martegani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Primm Srl
Original Assignee
Primm Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Primm Srl filed Critical Primm Srl
Publication of DE602005012812D1 publication Critical patent/DE602005012812D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE602005012812T 2005-06-13 2005-06-13 Heterodimere Peptide mit NGF Aktivität und deren Verwendung zur Behandlung von neurodegenerativen Krankheiten Active DE602005012812D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05012643A EP1734052B1 (de) 2005-06-13 2005-06-13 Heterodimere Peptide mit NGF Aktivität und deren Verwendung zur Behandlung von neurodegenerativen Krankheiten

Publications (1)

Publication Number Publication Date
DE602005012812D1 true DE602005012812D1 (de) 2009-04-02

Family

ID=35276556

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005012812T Active DE602005012812D1 (de) 2005-06-13 2005-06-13 Heterodimere Peptide mit NGF Aktivität und deren Verwendung zur Behandlung von neurodegenerativen Krankheiten

Country Status (5)

Country Link
US (1) US8461110B2 (de)
EP (2) EP1734052B1 (de)
AT (1) ATE423135T1 (de)
DE (1) DE602005012812D1 (de)
WO (1) WO2006133853A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1957986B1 (de) * 2005-11-22 2017-05-24 McGill University Frühgene mit reguliertem zwischenaugendruck und verwendungen davon
EP1921087A1 (de) * 2006-11-10 2008-05-14 Primm S.R.L. Verfahren zur Herstellung von cyclischen Peptiden
WO2008070513A1 (en) * 2006-12-01 2008-06-12 Alcon Research, Ltd. Modulation of polysialylated neural adhesion molecules (psa-ncam) as a regulator of ocular disease
CN101657212B (zh) * 2006-12-05 2014-03-19 皇家学习促进会/麦吉尔大学 Trk受体调节剂的使用方法
ITRM20070119A1 (it) * 2007-03-08 2008-09-09 Inbios S R L Udo del ngf per la preparazione di mendicamenti per la cura della gliosi reattiva
AU2008339904A1 (en) * 2007-12-20 2009-07-02 Cytos Biotechnology Ag Nerve growth factor conjugates and uses thereof
KR101565185B1 (ko) * 2008-04-04 2015-11-02 미메토젠 파르마슈티칼스 인크. 건안증을 치료하기 위한 베타-턴 펩티도미메틱 환상 화합물
KR20110130402A (ko) 2009-02-27 2011-12-05 미메토젠 파르마슈티칼스 인크. 망막색소변성증의 치료를 위한 펩티도미메틱 고리화합물
US9783601B2 (en) 2010-12-01 2017-10-10 Alderbio Holdings Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
US9539324B2 (en) 2010-12-01 2017-01-10 Alderbio Holdings, Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
US9078878B2 (en) 2010-12-01 2015-07-14 Alderbio Holdings Llc Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
US9067988B2 (en) 2010-12-01 2015-06-30 Alderbio Holdings Llc Methods of preventing or treating pain using anti-NGF antibodies
US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
US9884909B2 (en) 2010-12-01 2018-02-06 Alderbio Holdings Llc Anti-NGF compositions and use thereof
KR102061382B1 (ko) * 2012-06-22 2019-12-31 미메토젠 파르마슈티칼스 인크. 베타-턴 펩티도미메틱 환상 화합물의 합성

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9402331D0 (en) * 1994-02-07 1994-03-30 Univ Mcgill Nerve growth factor structural analogs and their uses
US5958875A (en) * 1996-03-29 1999-09-28 The Regents Of The University Of California Synthetic peptides derivatives with nerve growth factor-like neurotrophic activity

Also Published As

Publication number Publication date
EP1891099A1 (de) 2008-02-27
US20090318335A1 (en) 2009-12-24
WO2006133853A1 (en) 2006-12-21
EP1734052A1 (de) 2006-12-20
EP1734052B1 (de) 2009-02-18
US8461110B2 (en) 2013-06-11
ATE423135T1 (de) 2009-03-15

Similar Documents

Publication Publication Date Title
ATE423135T1 (de) Heterodimere peptide mit ngf aktivität und deren verwendung zur behandlung von neurodegenerativen krankheiten
BRPI0514115A (pt) terapia de combinação empregando-se proteìnas de fusão de transferrina compreendendo glp-1
ATE517119T1 (de) Einzelketteninsulin
DE602005010246D1 (de) Oligopeptide zur verringerung erhöhter blutharnstoffkonzentration
AR021448A1 (es) Metodo para producir un polipeptido quimerico
DK1877435T4 (da) Glucagon-lignende-peptid-2 (glp-2)-analoger
NZ562436A (en) Toll-like receptor 14 (TLR14) and use thereof
RS51544B (en) POBOLJŠANI SGP 130FC DIMERI
WO2007047829A3 (en) Novel heterodimeric proteins and uses thereof
ATE481978T1 (de) Zusammensetzungen und verfahren zur behandlung von herzkrankheiten
ATE375999T1 (de) Zusammensetzungen und verfahren zur behandlung von diabetes
ATE540980T1 (de) Proteinkomplex mit immunglobulinfragment und verfahren zu dessen herstellung
ATE525082T1 (de) Compstatin-analoga mit verbesserter wirkung
ATE495739T1 (de) Pharmazeutische zusammensetzungen und verfahren zur verwendung von levodopa und carbidopa
UA87128C2 (ru) ИММУНОГЛОБУЛИН АНТИ-EрCAM И СПОСОБ ЕГО ВВЕДЕНИЯ ДЛЯ ЛЕЧЕНИЯ ОНКОЛОГИЧЕСКИХ ЗАБОЛЕВАНИЙ
AR076977A1 (es) Proteinas precursoras repetitivas autoensambladas
CY1106070T1 (el) Πολυμορφισμοι στο γονιδιο c μεταφορας οργανικου ανιοντος ανθρωπου (oatp-c) - (organic anion transporter c gene)
EP2628746A3 (de) Verfahren zur Konzentration eines Polypeptids
DE60309865D1 (de) Glycoprotein vi - fc fusions protein zur behandlung von gefässerkrankungen
CY1114619T1 (el) Συνθετικα αναλογα πεπτιδιων νευρικης αναγεννησης
IS6072A (is) Æðasamloðunar sameindir og mótun á starfsemi þeirra
ATE557092T1 (de) Bv8-nukleinsäuren und polypeptide mit mitogener aktivität
ATE495193T1 (de) Bag3-antikörper zur nutzung in forschung, diagnose und der behandlung von krankheiten, an denen zelltod beteiligt ist
DE602005014990D1 (de) Morbus-crohn-antikörperepitoppeptid und reagens zum testen auf morbus crohn
ATE538806T1 (de) Peptide mit spezifischem sitz in herzgefässen und verwandte konjugate und verfahren

Legal Events

Date Code Title Description
8364 No opposition during term of opposition