ATE538806T1 - Peptide mit spezifischem sitz in herzgefässen und verwandte konjugate und verfahren - Google Patents

Peptide mit spezifischem sitz in herzgefässen und verwandte konjugate und verfahren

Info

Publication number
ATE538806T1
ATE538806T1 AT05795216T AT05795216T ATE538806T1 AT E538806 T1 ATE538806 T1 AT E538806T1 AT 05795216 T AT05795216 T AT 05795216T AT 05795216 T AT05795216 T AT 05795216T AT E538806 T1 ATE538806 T1 AT E538806T1
Authority
AT
Austria
Prior art keywords
peptidomimetic
methods
seq
amino acid
acid sequence
Prior art date
Application number
AT05795216T
Other languages
English (en)
Inventor
Lianglin Zhang
Jason Hoffman
Erkki Ruoslahti
Original Assignee
Burnham Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Burnham Inst filed Critical Burnham Inst
Application granted granted Critical
Publication of ATE538806T1 publication Critical patent/ATE538806T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT05795216T 2004-09-07 2005-09-07 Peptide mit spezifischem sitz in herzgefässen und verwandte konjugate und verfahren ATE538806T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93602704A 2004-09-07 2004-09-07
PCT/US2005/032205 WO2006029343A2 (en) 2004-09-07 2005-09-07 Peptides that selectively home to heart vasculature and related conjugates and methods

Publications (1)

Publication Number Publication Date
ATE538806T1 true ATE538806T1 (de) 2012-01-15

Family

ID=36037029

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05795216T ATE538806T1 (de) 2004-09-07 2005-09-07 Peptide mit spezifischem sitz in herzgefässen und verwandte konjugate und verfahren

Country Status (5)

Country Link
EP (1) EP1796707B1 (de)
JP (4) JP2008512391A (de)
CN (2) CN102558334B (de)
AT (1) ATE538806T1 (de)
WO (1) WO2006029343A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2099821B1 (de) 2006-12-01 2013-07-03 Georgetown University Medical School Gen und protein die nach entwicklungsmikrogefässen wandert
US9173890B2 (en) * 2007-09-20 2015-11-03 Abbott Cardiovascular Systems Inc. Sustained release of Apo A-I mimetic peptides and methods of treatment
CN110938128B (zh) * 2019-11-08 2021-07-13 上海交通大学 一种生物活性多肽pkcpkcdkevyfaervtsl及其制备方法和应用
CN112646022B (zh) * 2020-12-16 2022-03-29 熊猫乳品集团股份有限公司 一种生物活性肽pkcpkcdkevyfaerv及其制备方法和应用
CN113278591B (zh) * 2021-05-13 2023-07-25 厦门大学附属心血管病医院 一种心脏靶向性基因工程外泌体及其制备方法和应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8911333D0 (en) * 1989-05-17 1989-07-05 Plant Genetic Systems Nv New bacterial and/or bacteriostatic peptides,isolated from coleopteran insects
CA2139517A1 (en) * 1992-07-20 1994-02-03 Paul M. Keller Immunological conjugates of ompc and hiv-specific selected principal neutralization epitopes
JPH06211898A (ja) * 1992-12-25 1994-08-02 Takara Shuzo Co Ltd 神経α−カテニン
WO1996041172A1 (en) * 1995-06-07 1996-12-19 Cytogen Corporation Functional surrogates of analytes of interest and methods of obtaining and using same
JP2001501600A (ja) * 1996-09-10 2001-02-06 ザ バーナム インスティテュート 腫瘍ホーミング分子、それに由来する結合体、およびその使用方法
JP2001516055A (ja) * 1997-09-10 2001-09-25 ザ バーナム インスティチュート 腫瘍中の血管形成血管系にホーミングする分子を同定する方法
AU762991B2 (en) * 1998-03-13 2003-07-10 Burnham Institute, The Molecules that home to various selected organs or tissues
NO315238B1 (no) * 1998-05-08 2003-08-04 Gemvax As Peptider som stammer fra leserammeforskyvingsmutasjoner i TBF<beta>II- eller BAX-genet, og farmasöytiske sammensetninger inneholdende disse,nukleinsyresekvenser som koder for slike peptider, plasmider og virusvektoreromfattende slikenukleinsy
AU770381B2 (en) * 1999-01-22 2004-02-19 Burnham Institute, The Homing pro-apoptotic conjugates and methods of using same
US6528481B1 (en) * 1999-02-16 2003-03-04 The Burnam Institute NG2/HM proteoglycan-binding peptides that home to angiogenic vasculature and related methods
US20040031072A1 (en) * 1999-05-06 2004-02-12 La Rosa Thomas J. Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
US6303573B1 (en) * 1999-06-07 2001-10-16 The Burnham Institute Heart homing peptides and methods of using same
AU2903701A (en) * 1999-10-08 2001-04-23 Digiscents Olfactory receptor sequences
WO2001053342A1 (en) * 2000-01-21 2001-07-26 The Burnham Institute Chimeric prostate-homing peptides with pro-apoptotic activity
US20110131679A2 (en) * 2000-04-19 2011-06-02 Thomas La Rosa Rice Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement
EP1278854A2 (de) * 2000-04-21 2003-01-29 Corixa Corporation Zusammensetzungen und verfahren in der therapie und diagnostik von akne vulgaris
US7834146B2 (en) * 2000-05-08 2010-11-16 Monsanto Technology Llc Recombinant polypeptides associated with plants
CA2312646A1 (en) * 2000-06-28 2001-12-28 Institut National D'optique Hybrid micropackaging of microdevices
CN1575299A (zh) * 2001-09-05 2005-02-02 伦敦王室学院 导向多肽
ES2319624T3 (es) * 2001-11-08 2009-05-11 The Burnham Institute Peptidos que se dirigen al conjunto de vasos linfaticos del tumor y procedimientos de utilizacion de los mismos.

Also Published As

Publication number Publication date
EP1796707A4 (de) 2009-09-09
JP2016128505A (ja) 2016-07-14
WO2006029343A2 (en) 2006-03-16
CN101052408B (zh) 2013-03-27
JP6417347B2 (ja) 2018-11-07
JP2012051934A (ja) 2012-03-15
WO2006029343A3 (en) 2007-03-01
JP2015038064A (ja) 2015-02-26
CN102558334A (zh) 2012-07-11
EP1796707A2 (de) 2007-06-20
CN101052408A (zh) 2007-10-10
JP5993413B2 (ja) 2016-09-14
EP1796707B1 (de) 2011-12-28
CN102558334B (zh) 2016-08-03
JP2008512391A (ja) 2008-04-24

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