DE60230822D1 - Peptide mit homing für lymphgefässtumor und ihre verwendung - Google Patents

Peptide mit homing für lymphgefässtumor und ihre verwendung

Info

Publication number
DE60230822D1
DE60230822D1 DE60230822T DE60230822T DE60230822D1 DE 60230822 D1 DE60230822 D1 DE 60230822D1 DE 60230822 T DE60230822 T DE 60230822T DE 60230822 T DE60230822 T DE 60230822T DE 60230822 D1 DE60230822 D1 DE 60230822D1
Authority
DE
Germany
Prior art keywords
homing
tartor
lymphotic
peptides
lymphatic vasculature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60230822T
Other languages
English (en)
Inventor
Pirjo Laakkonen
Kimmo Porkka
Jason A Hoffman
Erkki Ruoslahti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanford Burnham Prebys Medical Discovery Institute
Original Assignee
Sanford Burnham Prebys Medical Discovery Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanford Burnham Prebys Medical Discovery Institute filed Critical Sanford Burnham Prebys Medical Discovery Institute
Application granted granted Critical
Publication of DE60230822D1 publication Critical patent/DE60230822D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DE60230822T 2001-11-08 2002-11-05 Peptide mit homing für lymphgefässtumor und ihre verwendung Expired - Lifetime DE60230822D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US779201A 2001-11-08 2001-11-08
PCT/US2002/035743 WO2003040693A2 (en) 2001-11-08 2002-11-05 Peptides that home to tumor lymphatic vasculature and methods of using same

Publications (1)

Publication Number Publication Date
DE60230822D1 true DE60230822D1 (de) 2009-02-26

Family

ID=21728162

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60230822T Expired - Lifetime DE60230822D1 (de) 2001-11-08 2002-11-05 Peptide mit homing für lymphgefässtumor und ihre verwendung

Country Status (7)

Country Link
EP (1) EP1581790B1 (de)
JP (1) JP2005514348A (de)
AT (1) ATE419861T1 (de)
AU (1) AU2002360350A1 (de)
DE (1) DE60230822D1 (de)
ES (1) ES2319624T3 (de)
WO (1) WO2003040693A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7501486B2 (en) 2004-09-07 2009-03-10 Burnham Institute For Medical Research Peptides that selectively home to heart vasculature and related conjugates and methods
EP1796707B1 (de) * 2004-09-07 2011-12-28 The Burnham Institute Peptide mit spezifischem sitz in herzgefässen und verwandte konjugate und verfahren
WO2007090194A2 (en) 2006-02-01 2007-08-09 The Burnham Institute For Medical Research Lymphatic zip codes in tumors and pre-malignant lesions
EP2043696B1 (de) 2006-07-13 2015-02-25 Burnham Institute for Medical Research Verfahren und zusammensetzungen zum gc1qr/p32-targeting
US8877889B2 (en) * 2009-09-02 2014-11-04 Industry-Academic Cooperation Foundation, Chosun University Tumor cell-killing peptides
US8906355B2 (en) * 2009-10-29 2014-12-09 Lucia Irene Gonzalez Synthetic stereoisomer peptides in the retro-inverso and inverso configuration, and with cyclic and linear structure, their polymer conjugates, their encapsulation in polymer particles, and uses thereof
JP2013525285A (ja) * 2010-04-08 2013-06-20 サンフォード−バーナム メディカル リサーチ インスティテュート 化合物の送達を増強するための方法および組成物
US9975933B2 (en) * 2013-05-23 2018-05-22 Ajou University Industry-Academic Cooperation Foundation Tumor tissue-penetrating peptide specific to neuropilin and fusion protein having same peptide fused therein
US10669311B2 (en) 2015-04-23 2020-06-02 Sanford Burnham Prebys Medical Discovery Institute Targeted delivery system and methods of use therefor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5789542A (en) 1994-04-22 1998-08-04 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Amphipathic peptides
EP0876611A1 (de) * 1995-09-11 1998-11-11 La Jolla Cancer Research Foundation Moleküle die sich in ausgewählten organen oder geweben in-vivo einfinden und verfahren zu ihrer identifizierung
JP2001501600A (ja) * 1996-09-10 2001-02-06 ザ バーナム インスティテュート 腫瘍ホーミング分子、それに由来する結合体、およびその使用方法
US6287756B1 (en) * 1997-05-05 2001-09-11 Ludwig Institute For Cancer Research Methods for determining presence of cancer in a sample by determining expression of an SSX gene
JP4531267B2 (ja) 1999-01-22 2010-08-25 ザ バーナム インスティチュート ホーミングプロアポトーシス結合体およびホーミングプロアポトーシス結合体を使用する方法

Also Published As

Publication number Publication date
EP1581790B1 (de) 2009-01-07
ATE419861T1 (de) 2009-01-15
AU2002360350A8 (en) 2006-11-02
ES2319624T3 (es) 2009-05-11
WO2003040693A2 (en) 2003-05-15
JP2005514348A (ja) 2005-05-19
EP1581790A4 (de) 2006-07-19
EP1581790A2 (de) 2005-10-05
AU2002360350A1 (en) 2003-05-19
WO2003040693A3 (en) 2006-02-09

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