CY1108691T1 - Πολυπεπτιδια - Google Patents

Πολυπεπτιδια

Info

Publication number
CY1108691T1
CY1108691T1 CY20091100035T CY091100035T CY1108691T1 CY 1108691 T1 CY1108691 T1 CY 1108691T1 CY 20091100035 T CY20091100035 T CY 20091100035T CY 091100035 T CY091100035 T CY 091100035T CY 1108691 T1 CY1108691 T1 CY 1108691T1
Authority
CY
Cyprus
Prior art keywords
variable domain
polypeptide
antibody
peg
linked
Prior art date
Application number
CY20091100035T
Other languages
English (en)
Inventor
Amrik Basran
Original Assignee
Domantis Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35811376&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1108691(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/GB2003/002804 external-priority patent/WO2004003019A2/en
Application filed by Domantis Limited filed Critical Domantis Limited
Publication of CY1108691T1 publication Critical patent/CY1108691T1/el

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Classifications

    • C—CHEMISTRY; METALLURGY
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    • C07K16/005—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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    • C07—ORGANIC CHEMISTRY
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K—PEPTIDES
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K—PEPTIDES
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    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Hematology (AREA)
  • Virology (AREA)
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Abstract

Η παρούσα εφεύρεση περιλαμβάνει ένα φυσικώς απαντώμενο ή συνθετικό πολυπεπτίδιο που συνδέεται με πολυμερές που περιέχει μια ή περισσότερες περιοχές αντισώματος.
CY20091100035T 2003-06-30 2009-01-14 Πολυπεπτιδια CY1108691T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/GB2003/002804 WO2004003019A2 (en) 2002-06-28 2003-06-30 Immunoglobin single variant antigen-binding domains and dual-specific constructs
US50961303P 2003-10-08 2003-10-08
US53507604P 2004-01-08 2004-01-08
EP04737302A EP1639011B1 (en) 2003-06-30 2004-06-30 Pegylated single domain antibodies (dAb)

Publications (1)

Publication Number Publication Date
CY1108691T1 true CY1108691T1 (el) 2014-04-09

Family

ID=35811376

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100035T CY1108691T1 (el) 2003-06-30 2009-01-14 Πολυπεπτιδια

Country Status (16)

Country Link
US (4) US20060286066A1 (el)
EP (3) EP1639011B1 (el)
JP (2) JP5087274B2 (el)
CN (1) CN1845938B (el)
AT (1) ATE414106T1 (el)
AU (3) AU2004220325B2 (el)
CA (2) CA2529819A1 (el)
CY (1) CY1108691T1 (el)
DE (1) DE602004017726D1 (el)
DK (1) DK1639011T3 (el)
ES (1) ES2315664T3 (el)
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JP2008500268A (ja) 2008-01-10
AU2004220325B2 (en) 2011-05-12
DE602004017726D1 (de) 2008-12-24
EP2221317A2 (en) 2010-08-25
AU2004280288B2 (en) 2007-02-01
ZA200702879B (en) 2008-08-27
CN1845938A (zh) 2006-10-11
US20090148434A1 (en) 2009-06-11
ES2315664T3 (es) 2009-04-01
WO2005035572A3 (en) 2007-01-04
ATE414106T1 (de) 2008-11-15
EP2221317A3 (en) 2011-07-27
JP5087274B2 (ja) 2012-12-05
US20070065440A1 (en) 2007-03-22
EP1720906A2 (en) 2006-11-15
WO2004081026A2 (en) 2004-09-23
AU2004220325A1 (en) 2004-09-23
AU2004280288A2 (en) 2005-04-21
JP2007516195A (ja) 2007-06-21
PT1639011E (pt) 2009-01-20
EP1639011A2 (en) 2006-03-29
CA2539999A1 (en) 2005-04-21
CN1845938B (zh) 2010-05-26
AU2011200930A1 (en) 2011-03-24
PL1639011T3 (pl) 2009-05-29
WO2005035572A2 (en) 2005-04-21
US20090082550A1 (en) 2009-03-26
EP1639011B1 (en) 2008-11-12
AU2004280288A1 (en) 2005-04-21
WO2004081026A3 (en) 2005-01-27
AU2011200930B2 (en) 2013-10-24
SI1639011T1 (sl) 2009-04-30
DK1639011T3 (da) 2009-02-16
CA2529819A1 (en) 2004-09-23
US20060286066A1 (en) 2006-12-21

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