ATE419861T1 - Peptide mit homing für lymphgefässtumor und ihre verwendung - Google Patents

Peptide mit homing für lymphgefässtumor und ihre verwendung

Info

Publication number
ATE419861T1
ATE419861T1 AT02795599T AT02795599T ATE419861T1 AT E419861 T1 ATE419861 T1 AT E419861T1 AT 02795599 T AT02795599 T AT 02795599T AT 02795599 T AT02795599 T AT 02795599T AT E419861 T1 ATE419861 T1 AT E419861T1
Authority
AT
Austria
Prior art keywords
homing peptides
lymph vessel
vessel tumor
tumor
lymphatic vasculature
Prior art date
Application number
AT02795599T
Other languages
English (en)
Inventor
Pirjo Laakkonen
Kimmo Porkka
Jason Hoffman
Erkki Ruoslahti
Original Assignee
Burnham Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Burnham Inst filed Critical Burnham Inst
Application granted granted Critical
Publication of ATE419861T1 publication Critical patent/ATE419861T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AT02795599T 2001-11-08 2002-11-05 Peptide mit homing für lymphgefässtumor und ihre verwendung ATE419861T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US779201A 2001-11-08 2001-11-08

Publications (1)

Publication Number Publication Date
ATE419861T1 true ATE419861T1 (de) 2009-01-15

Family

ID=21728162

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02795599T ATE419861T1 (de) 2001-11-08 2002-11-05 Peptide mit homing für lymphgefässtumor und ihre verwendung

Country Status (7)

Country Link
EP (1) EP1581790B1 (de)
JP (1) JP2005514348A (de)
AT (1) ATE419861T1 (de)
AU (1) AU2002360350A1 (de)
DE (1) DE60230822D1 (de)
ES (1) ES2319624T3 (de)
WO (1) WO2003040693A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101052408B (zh) * 2004-09-07 2013-03-27 伯纳姆研究院 选择性锚定到心脏脉管系统上的肽和相关结合物和方法
US7501486B2 (en) 2004-09-07 2009-03-10 Burnham Institute For Medical Research Peptides that selectively home to heart vasculature and related conjugates and methods
WO2007090194A2 (en) 2006-02-01 2007-08-09 The Burnham Institute For Medical Research Lymphatic zip codes in tumors and pre-malignant lesions
JP2009543806A (ja) * 2006-07-13 2009-12-10 バーナム インスティテュート フォー メディカル リサーチ ｇＣ１ｑＲ／ｐ３２を標的化するための方法および組成物
WO2011027980A2 (en) * 2009-09-02 2011-03-10 Industry-Academic Cooperation Foundation, Chosun University Tumor cell-killing peptides
US8906355B2 (en) * 2009-10-29 2014-12-09 Lucia Irene Gonzalez Synthetic stereoisomer peptides in the retro-inverso and inverso configuration, and with cyclic and linear structure, their polymer conjugates, their encapsulation in polymer particles, and uses thereof
US20110262347A1 (en) * 2010-04-08 2011-10-27 The Salk Institute For Biological Studies Methods and compositions for enhanced delivery of compounds
EP3000825A4 (de) * 2013-05-23 2017-02-08 Ajou University Industry-Academic Cooperation Foundation Transtumorales peptid spezifisch für neuropilin und fusionsprotein mit kondensiertem peptid
US10669311B2 (en) 2015-04-23 2020-06-02 Sanford Burnham Prebys Medical Discovery Institute Targeted delivery system and methods of use therefor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5789542A (en) 1994-04-22 1998-08-04 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Amphipathic peptides
WO1997010507A1 (en) * 1995-09-11 1997-03-20 La Jolla Cancer Research Foundation Molecules that home to a selected organ or tissue in vivo and methods of identifying same
WO1998010795A2 (en) * 1996-09-10 1998-03-19 The Burnham Institute Tumor homing molecules, conjugates derived therefrom, and methods of using same
US6287756B1 (en) * 1997-05-05 2001-09-11 Ludwig Institute For Cancer Research Methods for determining presence of cancer in a sample by determining expression of an SSX gene
JP4531267B2 (ja) 1999-01-22 2010-08-25 ザ バーナム インスティチュート ホーミングプロアポトーシス結合体およびホーミングプロアポトーシス結合体を使用する方法

Also Published As

Publication number Publication date
JP2005514348A (ja) 2005-05-19
WO2003040693A3 (en) 2006-02-09
WO2003040693A2 (en) 2003-05-15
ES2319624T3 (es) 2009-05-11
DE60230822D1 (de) 2009-02-26
AU2002360350A1 (en) 2003-05-19
EP1581790B1 (de) 2009-01-07
AU2002360350A8 (en) 2006-11-02
EP1581790A4 (de) 2006-07-19
EP1581790A2 (de) 2005-10-05

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties