UA87128C2 - ИММУНОГЛОБУЛИН АНТИ-EрCAM И СПОСОБ ЕГО ВВЕДЕНИЯ ДЛЯ ЛЕЧЕНИЯ ОНКОЛОГИЧЕСКИХ ЗАБОЛЕВАНИЙ - Google Patents
ИММУНОГЛОБУЛИН АНТИ-EрCAM И СПОСОБ ЕГО ВВЕДЕНИЯ ДЛЯ ЛЕЧЕНИЯ ОНКОЛОГИЧЕСКИХ ЗАБОЛЕВАНИЙInfo
- Publication number
- UA87128C2 UA87128C2 UAA200608985A UAA200608985A UA87128C2 UA 87128 C2 UA87128 C2 UA 87128C2 UA A200608985 A UAA200608985 A UA A200608985A UA A200608985 A UAA200608985 A UA A200608985A UA 87128 C2 UA87128 C2 UA 87128C2
- Authority
- UA
- Ukraine
- Prior art keywords
- administration
- treatment
- immunoglobulin
- eрcam
- oncological diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
Изобретение относится к области медицины и касается способа лечения опухолевых заболеваний человека путем введения пациентам человеческого иммуноглобулина, который состояит из тяжелой цепи с аминокислотной последовательностью SEQ ID NO: 1 и из легкой цепи с аминокислотной последовательностью SEQ ID NO: 2, специфично связывается с человеческим антигеном ЕрСАМ и имеет период полувыведения из сыворотки, как минимум, 15 дней.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/778,915 US20050180979A1 (en) | 2004-02-13 | 2004-02-13 | Anti-EpCAM immunoglobulins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA87128C2 true UA87128C2 (ru) | 2009-06-25 |
Family
ID=34838270
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200608985A UA87128C2 (ru) | 2004-02-13 | 2005-02-09 | ИММУНОГЛОБУЛИН АНТИ-EрCAM И СПОСОБ ЕГО ВВЕДЕНИЯ ДЛЯ ЛЕЧЕНИЯ ОНКОЛОГИЧЕСКИХ ЗАБОЛЕВАНИЙ |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US20050180979A1 (ru) |
| EP (2) | EP1713830B1 (ru) |
| JP (1) | JP5220315B2 (ru) |
| KR (1) | KR101236224B1 (ru) |
| CN (1) | CN1976951B (ru) |
| AT (1) | ATE437186T1 (ru) |
| AU (1) | AU2005215874B2 (ru) |
| BR (1) | BRPI0507660A (ru) |
| CA (1) | CA2555694C (ru) |
| DE (1) | DE602005015544D1 (ru) |
| DK (1) | DK1713830T3 (ru) |
| EA (1) | EA011951B1 (ru) |
| ES (1) | ES2328159T3 (ru) |
| HK (1) | HK1096103A1 (ru) |
| IL (1) | IL177069A (ru) |
| MX (1) | MXPA06008942A (ru) |
| NO (1) | NO339364B1 (ru) |
| NZ (1) | NZ549125A (ru) |
| PL (1) | PL1713830T3 (ru) |
| PT (1) | PT1713830E (ru) |
| SI (1) | SI1713830T1 (ru) |
| UA (1) | UA87128C2 (ru) |
| WO (1) | WO2005080428A2 (ru) |
| ZA (1) | ZA200606083B (ru) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9169516B2 (en) | 2003-01-24 | 2015-10-27 | University Of Utah Research Foundation | Methods of predicting mortality risk by determining telomere length |
| WO2007090670A1 (en) * | 2006-02-09 | 2007-08-16 | Micromet Ag | Treatment of metastatic breast cancer |
| EP1865001A1 (en) * | 2006-06-08 | 2007-12-12 | Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh | Specific protease inhibitors and their use in cancer therapy |
| EP2041181B1 (en) * | 2006-06-08 | 2011-05-18 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Specific protease inhibitors and their use in cancer therapy |
| ES2367675T3 (es) | 2007-04-04 | 2011-11-07 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Anticuerpo anti-epcam y usos del mismo. |
| JP5840950B2 (ja) | 2008-12-22 | 2016-01-06 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション | 単色マルチプレックス定量ｐｃｒ |
| AU2010295172B2 (en) * | 2009-09-21 | 2016-08-04 | Ranju Ralhan | Methods and compositions for the diagnosis and treatment of thyroid cancer |
| EP2819695B1 (en) * | 2012-03-02 | 2018-06-27 | Academia Sinica | ANTI-EPITHELIAL CELL ADHESION MOLECULE (EpCAM) ANTIBODIES AND METHODS OF USE THEREOF |
| CN103387988B (zh) * | 2012-09-24 | 2016-01-06 | 厦门大学 | 上皮细胞粘附分子的核酸适体EpCAM Ccut及其制备方法 |
| JP6546158B2 (ja) | 2013-05-22 | 2019-07-17 | テロメア ダイアグノスティクス インコーポレイテッド | 短いテロメアの存在量の測定 |
| CN103275226B (zh) * | 2013-06-09 | 2017-08-29 | 中国科学技术大学 | 特异性抗人上皮细胞粘附分子（EpCAM）的单克隆抗体的制备、鉴定及应用 |
| AU2015372584A1 (en) | 2014-12-30 | 2017-06-29 | Telomere Diagnostics, Inc. | Multiplex quantitative PCR |
| CA3003482A1 (en) * | 2015-11-19 | 2017-05-26 | Revitope Limited | Functional antibody fragment complementation for a two-components system for redirected killing of unwanted cells |
| AU2017301826A1 (en) | 2016-07-26 | 2019-03-14 | Tessa Therapeutics Ltd. | Chimeric antigen receptor |
| WO2020018964A1 (en) | 2018-07-20 | 2020-01-23 | Fred Hutchinson Cancer Research Center | Compositions and methods for controlled expression of antigen-specific receptors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5853697A (en) * | 1995-10-25 | 1998-12-29 | The United States Of America, As Represented By The Department Of Health & Human Services | Methods of treating established colitis using antibodies against IL-12 |
| CN100387621C (zh) * | 1997-04-14 | 2008-05-14 | 麦可麦脱股份公司 | 抗人抗原受体的新的生产方法及其用途 |
| US6855544B1 (en) * | 1999-04-15 | 2005-02-15 | Crucell Holland B.V. | Recombinant protein production in a human cell |
| US7605238B2 (en) * | 1999-08-24 | 2009-10-20 | Medarex, Inc. | Human CTLA-4 antibodies and their uses |
| BR0209177A (pt) * | 2001-05-03 | 2004-10-05 | Merck Patent Gmbh | Anticorpo especìfico a tumor recombinante e uso do mesmo |
| US20030175268A1 (en) * | 2002-01-11 | 2003-09-18 | Saint-Remy Jean-Marie R. | Method and pharmaceutical composition for preventing and/or treating systemic inflammatory response syndrome |
| JP2006508899A (ja) * | 2002-05-20 | 2006-03-16 | アブジエニツクス・インコーポレイテツド | ＥＧＦｒに対する抗体を使用する腎癌の治療方法 |
-
2004
- 2004-02-13 US US10/778,915 patent/US20050180979A1/en not_active Abandoned
-
2005
- 2005-02-09 WO PCT/EP2005/001307 patent/WO2005080428A2/en active Application Filing
- 2005-02-09 PL PL05707293T patent/PL1713830T3/pl unknown
- 2005-02-09 NZ NZ549125A patent/NZ549125A/en not_active IP Right Cessation
- 2005-02-09 SI SI200530759T patent/SI1713830T1/sl unknown
- 2005-02-09 EP EP05707293A patent/EP1713830B1/en active Active
- 2005-02-09 KR KR1020067016339A patent/KR101236224B1/ko not_active IP Right Cessation
- 2005-02-09 CN CN2005800099764A patent/CN1976951B/zh not_active Expired - Fee Related
- 2005-02-09 MX MXPA06008942A patent/MXPA06008942A/es active IP Right Grant
- 2005-02-09 AT AT05707293T patent/ATE437186T1/de active
- 2005-02-09 AU AU2005215874A patent/AU2005215874B2/en not_active Ceased
- 2005-02-09 UA UAA200608985A patent/UA87128C2/ru unknown
- 2005-02-09 EP EP09165284A patent/EP2107071A3/en not_active Withdrawn
- 2005-02-09 US US10/589,450 patent/US20070274982A1/en not_active Abandoned
- 2005-02-09 ES ES05707293T patent/ES2328159T3/es active Active
- 2005-02-09 JP JP2006552536A patent/JP5220315B2/ja not_active Expired - Fee Related
- 2005-02-09 DK DK05707293T patent/DK1713830T3/da active
- 2005-02-09 CA CA2555694A patent/CA2555694C/en not_active Expired - Fee Related
- 2005-02-09 EA EA200601386A patent/EA011951B1/ru not_active IP Right Cessation
- 2005-02-09 DE DE602005015544T patent/DE602005015544D1/de active Active
- 2005-02-09 BR BRPI0507660-9A patent/BRPI0507660A/pt not_active Application Discontinuation
- 2005-02-09 PT PT05707293T patent/PT1713830E/pt unknown
-
2006
- 2006-07-21 ZA ZA200606083A patent/ZA200606083B/en unknown
- 2006-07-25 IL IL177069A patent/IL177069A/en not_active IP Right Cessation
- 2006-09-13 NO NO20064136A patent/NO339364B1/no not_active IP Right Cessation
-
2007
- 2007-02-23 HK HK07102075.7A patent/HK1096103A1/xx not_active IP Right Cessation
-
2012
- 2012-06-01 US US13/486,749 patent/US20120294873A1/en not_active Abandoned
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